Protein details/Phosphorylation

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The Phosphorylation section of the Protein details page in GlyGen provides the detailed list of phosphorylation sites and kinase proteins responsible for phosphorylation.

Phosphorylation

Screenshot of the Phosphorylation section on the Protein details page in GlyGen.

This section provides the following information:

  • Source - Evidence linking to the databases and papers that provided the phosphorylation information.
  • Kinase Protein - GlyGen ID of the enzyme responsible for catalyzing the covalent addition of a phosphate group to the protein. Eg. Q6P1J9-1
  • Kinase Gene - Name of the gene that encodes the kinase protein. Eg. CDC73
  • Residue - Residue on which phosphorylation occurs by kinase protein; commonly occurs on amino acids serine and threonine, and occasionally tyrosine. Eg. Ser322
  • Notes - Additional information about the entry such as curation notes, phosphorylation subtype, remarks, etc.

Source of information

The Phosphorylation data is collected and integrated from UniProtKB, PubMed, and iPTMnet databases.

  • UniProtKB - only reported sites information and predicted information is downloaded from UniProtKB.
  • iPTMnet - only reported sites information and predicted information is downloaded from iPTMnet

Data access

The collected data is processed and stored in data.glygen.org in following datasets.

Homo Sapiens (Human) Datasets

  • Human Phosphorylation Sites (UniProtKB; GLY_000274)
  • Human Phosphorylation Sites (iPTMNet; GLY_000519)

Hepatitis C Virus Datasets

  • HCV1a Phosphorylation Sites (UniProtKB; GLY_000384)
  • HCV1b Phosphorylation Sites (UniProtKB; GLY_000385)

SARS Coronavirus Datasets

  • SARS-CoV1 Phosphorylation Sites (UniProtKB; GLY_000474)
  • SARS-CoV2 Phosphorylation Sites (UniProtKB; GLY_000475)

Mus musculus (Mouse) Datasets

  • Mouse Phosphorylation Sites (UniProtKB; GLY_000254)
  • Mouse Phosphorylation Sites (iPTMNet; GLY_000520)

Rattus norvegicus (Rat) Datasets

Data harmonization

Data filtering