Protein details/Glycation: Difference between revisions

Latest revision as of 15:17, 9 December 2021

The Glycation section of the Protein details page in GlyGen provides a detailed list of sites with non-enzymatic, covalently linked glucose residues, including the type of attachment and the location on the amino acid sequence.

Glycation

This section provides the following information:

Source - GlyGen evidence linking to the databases and papers that provided the glycation information
Type - Type of glycation. Eg. N-linked
Relation - Relationship to the amino acid residue. Eg. attached
Residue - Amino acid residue of the given protein along with its position. Eg. Asn294
Note - Additional information about the entry such as curation notes, N-linked (Glc) (glycation) lysine, remarks, etc.

Source of information

The Glycation data is collected and integrated from UniProtKB databases.

UniProtKB - only annotated as glycation in UniProtKB when there is experimental evidence

Data access

The collected data is processed and stored at data.glygen.org in the following datasets:

Homo Sapiens (Human) Datasets

Human Glycation Sites (UniProtKB; GLY_000522)

Mus musculus (Mouse) Datasets

Mouse Glycation Sites (UniProtKB; GLY_000523)

Rattus norvegicus (Rat) Datasets

Rat Glycation Sites (UniProtKB; GLY_000524)

Data harmonization

Data filtering

@@ Line 1: / Line 1: @@
-The glycation section of the [[Protein information]] page in GlyGen provides a detailed list of sites with non-enzymatic, covalently linked glucose residues, including the type of attachment and the location on the amino acid sequence.
+The Glycation section of the [[Protein details]] page in GlyGen provides a detailed list of sites with non-enzymatic, covalently linked glucose residues, including the type of attachment and the location on the amino acid sequence.
 ==Glycation==
@@ Line 5: / Line 5: @@
 This section provides the following information:
-*'''Source''' -
+*'''Source''' - GlyGen evidence linking to the databases and papers that provided the glycation information
-*'''Type''' -
+*'''Type''' - Type of glycation. Eg. N-linked
-*'''Relation''' -
+*'''Relation''' - Relationship to the amino acid residue. Eg. attached
-*'''Residue''' -
+*'''Residue''' - Amino acid residue of the given protein along with its position. Eg. Asn294
-*'''Note''' -
+*'''Note''' - Additional information about the entry such as curation notes, N-linked (Glc) (glycation) lysine, remarks, etc.
 ==Source of information==
-The Glycation data is collected and integrated from '''[https://uniprot.org UniProtKB]''' and '''[https://pubmed.ncbi.nlm.nih.gov/ PubMed]''' databases.
+The Glycation data is collected and integrated from '''[https://uniprot.org UniProtKB]''' databases.
-{{Expand section|small=no}}
+'''[https://uniprot.org UniProtKB]''' - only annotated as glycation in UniProtKB when there is experimental evidence
 ==Data access==
@@ Line 21: / Line 21: @@
 Homo Sapiens (Human) Datasets
-*
+*Human Glycation Sites (UniProtKB; [https://data.glygen.org/GLY_000522 GLY_000522])
+Mus musculus (Mouse) Datasets
+*Mouse Glycation Sites (UniProtKB; [https://data.glygen.org/GLY_000523 GLY_000523])
+Rattus norvegicus (Rat) Datasets
+*Rat Glycation Sites (UniProtKB; [https://data.glygen.org/GLY_000524 GLY_000524])
+*
 ==Data harmonization==