Glycan structure dictionary
This is work in progress.
Glycan Structure Dictionary. Terms represent commonly used words to describe glycan structures in publications. If you feel that a term is missing, please contact us at https://www.glygen.org/contact-us/ with the following information: Term name | at least two PMIDs where the term is used.
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List of terms
bisialo-biantennary complex-type
Fully sialylated biantennary N-glycan
triantennary trisialylated fucosylated
fucose-containing tetraantennary
fucosylated asialo-biantennary
fucosylated bisialo-biantennary
core fucosylated biantennary complex-type
di-fucosylated tetra-antennary N-glycans
nonfucosylated biantennary N-linked structures
disialylated biantennary complex type
trisialylated complex-type oligosaccharide-alditols
Mono-sulfated globopentaosylceramide
Disialosyl globopentaosylceramide
GalNAc Disialyl Lc4 (Hexasaccharide)
Details
term (main_entry) : core fucosylated
term_in_sentence : The approach was validated for selective capture and analysis of core fucosylated N-glycans present in complex glycan mixtures derived from mammalian serum IgG.[PMID:27678371]
publication : 27678371|26514868|15538974|24914453|17049014|32078267|31268672|28674882|29956878|27798819|32044029|30962950|31548313|30907281|29090617|29571940|28800497|27629418|29733746|31623829|28768188|26897254|31451706|26514868|29427759|28982386|26587313|30940702|15538974|31249452|27282921|31229844|30445455|31325506|24732908|29209018|26965517|28609658|24914453|25573275|17049014|19218400|27012207|27139574|32078267|25861849|32561391|21374780|31669139|25732060|29408166|31268672|30472795|30614075|19003000|25664929
definition : Modification of the N-glycan core structure with fucose moiety attached at the innermost GlcNAc by FUT8 enzyme. Core Fuc is found on paucimannose, hybrid and complex type N-glycans. [MT, RN, https://doi.org/10.1016/bs.acr.2014.11.006].
term_xref :
synonymns : Core Fuc|6-linked Fuc|Fuca6 to chitobiose core|a6-linked Fuc|a1-6 Fuc|Fuca6 to chitobiose core|Fuc a1-6 to chitobiose core|Fuca6 to internal GlcNAc|Fuc a1-6 to internal GlcNAc
function : Required for signaling through TCR [PMID: 29434598]|VGF, PDGFr, and EGFr and TGFbeta receptor dysregulation in Fut8 KO mice [PMID:17132494]|IgG-Fcg receptor interactions destabilized by core Fuc [PMID:29062024]
disease_associations : Emphysema[MT]|systemic lupus erythematosus[MT]lung cancer[MT]|autoimmunity[MT]|tumor metastasis[MT]
wikipedia :
essentials_of_glycobiology :
hierarchy :
notes :