Glycan structure dictionary

This is work in progress.

Glycan Structure Dictionary. Terms represent commonly used words to describe glycan structures in publications. If you feel that a term is missing, please contact us at https://www.glygen.org/contact-us/ with the following information: Term name | at least two PMIDs where the term is used.

List of terms

core fucosylated

trimannosyl core

triantennary complex

biantennary complex

high-mannose

N-linked glycans

complex-type N-glycans

paucimannose

hybrid

biantennary

asialo-biantennary

bisialo-biantennary

bisialo-biantennary complex-type

sialylated biantennary

Fully sialylated biantennary N-glycan

triantennary

Tri-antennary N-glycans

triantennary complex type

tetraantennary complex-type

tetraantennary

tetrasialylated diantennary

triantennary sialylated

triantennary trisialylated fucosylated

bisecting GlcNAc

fucose-containing tetraantennary

fucosylated asialo-biantennary

fucosylated biantennary

fucosylated bisialo-biantennary

fucosylated N-glycans

fucosylated triantennary

core-fucosylated biantennary

core fucosylated biantennary complex-type

di-fucosylated tetra-antennary N-glycans

nonfucosylated

non-fucosylated biantennary

nonfucosylated biantennary N-linked structures

non-fucosylated triantennary

sialylated complex-type

sialylated diantennary

sialylated tetraantennary

monosialylated

monosialyl-biantennary

disialylated biantennary

disialylated biantennary complex type

Disialylated fucosylated

trisialylated

trisialylated complex-type oligosaccharide-alditols

trisialylated diantennary

trisialylated triantennary

nonsialylated

desialylated

desialylated tetrasaccharide

O-linked glycans

O-mannosyl glycan

O-Linked mannose

O-GlcNAc

O-fucose glycans

Tn antigen

sialyl-Tn antigen

T antigen

Sialyl T antigen

Di-sialyl T antigen

core 2

core 3

core 4

HNK-1

Lewis X

sialyl Lewis A

3'-sulfo-Lewis a

sialyl Lewis X

3'-sulfo-Lewis x

Lewis y

VIM-2

disialyl Lewis a

sialyl Lewis X-i

Forssman antigen

SSEA-1

SSEA-3

SSEA-4

Glucosylceramide

lactosylceramide

Lactotriaosylceramide

fucosyl GM1

N-acetyl GM2

N-glycolyl GM2

9-O-acetyl GD3

9-O-acetyl sialic acid

globotriaosylceramide

globotetraosylceramide

Galactosylceramide

alpha-galactosylceramide

asialo-GM1

GD1

GT1a

GQ1b

Mono-sulfated globopentaosylceramide

Gb5

GM4

Isoglobotetraosylceramide

Sialosyl paragloboside

para-Forssman glycolipid

B-GD1b

Forssman glycolipid

GP1c

Disialosyl globopentaosylceramide

Paragloboside

LcGg4

Sialopentaosylceramide

GM3

GM2

GM1

B-GM1

monosialyl-Gb5

Disialyl Gb5

cisGM1

GD1a

GT1a alpha

GD3

GD2

GD1b

GT3

GT2

GT1b

GT1c

GQ1c

Galabiosylceramide

cytolipin R

chitin

chondroitin sulfate

dermatan sulfate

heparan sulfate

heparin

keratan sulfate

N-acetyllactosamine

LacdiNAc

H type 2

alpha-gal antigen

Polysialic acid

Lewis A

Lewis B

blood group H type 1

i antigen

Sd(a)/Cad

H type 3

A type 2

6'-Sulfo Sialyl Lewis x

A2

Cyclic sialyl 6-sulfo Lewis x

Blood group B type 1

Blood group H (type 4)

Blood group B (type 4)

Blood group A (type 4)

C2-O-sLex

LewisX-LewisX

SDLex

Blood group B (type 2)

Fucosylated LDN

blood group A(1)

Blood group B (type 1)

Blood group A (type 1)

P1 antigen

Trifucosyl-Lewis b Antigen

Dimeric Lewis x

Trifucosyl-Lewis y

Disialyl I

GalNAc Disialyl Lc4 (Hexasaccharide)

I Antigen

6-Sulfo LacNAc

Blood Group A Trisaccharide

core fucosylated

term (main_entry) : core fucosylated term_in_sentence : The approach was validated for selective capture and analysis of core fucosylated N-glycans present in complex glycan mixtures derived from mammalian serum IgG.[PMID:27678371] publication : 27678371|26514868|15538974|24914453|17049014|32078267|31268672|28674882|29956878|27798819|32044029|30962950|31548313|30907281|29090617|29571940|28800497|27629418|29733746|31623829|28768188|26897254|31451706|26514868|29427759|28982386|26587313|30940702|15538974|31249452|27282921|31229844|30445455|31325506|24732908|29209018|26965517|28609658|24914453|25573275|17049014|19218400|27012207|27139574|32078267|25861849|32561391|21374780|31669139|25732060|29408166|31268672|30472795|30614075|19003000|25664929 definition : Modification of the N-glycan core structure with fucose moiety attached at the innermost GlcNAc by FUT8 enzyme. Core Fuc is found on paucimannose, hybrid and complex type N-glycans. [MT, RN, https://doi.org/10.1016/bs.acr.2014.11.006]. term_xref : synonymns : Core Fuc|6-linked Fuc|Fuca6 to chitobiose core|a6-linked Fuc|a1-6 Fuc|Fuca6 to chitobiose core|Fuc a1-6 to chitobiose core|Fuca6 to internal GlcNAc|Fuc a1-6 to internal GlcNAc function : Required for signaling through TCR [PMID: 29434598]|VGF, PDGFr, and EGFr and TGFbeta receptor dysregulation in Fut8 KO mice [PMID:17132494]|IgG-Fcg receptor interactions destabilized by core Fuc [PMID:29062024] disease_associations : Emphysema[MT]|systemic lupus erythematosus[MT]lung cancer[MT]|autoimmunity[MT]|tumor metastasis[MT] wikipedia : high mannose essentials_of_glycobiology : hierarchy : notes :

trimannosyl core

term (main_entry) : trimannosyl core term_in_sentence : This glycoengineered H. polymorpha strain produced glycoproteins mainly containing trimannosyl core N-glycan (Man(3)GlcNAc(2)), which is the common core backbone of various human-type N-glycans.[PMID:18320567] publication : 18320567|27629418|26514868|26821880|2477227|6213618|31747570|29273674|31064325|1291063|28353332|1421754|29666272|11421342|15648688|28179475|28903882|27189951|9455915|22768188|9254048|8721739|2249985|22933239|25629585|24489949|2981047|11067815|1729985|1710649|16672288|2719668|19003000|23025485|22500028|10409642|1325461|23136055|23085445|21656680|22448293|22132163|1425696|20696712|18056652|15084511|18633282|15814299 definition : A glycan that constitutes the core structure common to all high-mannose, complex, or hybrid N-glycans. The trimannosyl core composition is Man3 GlcNAc2 and includes a chitobiose at the reducing terminal which is extended by a single b-linked Man residue. The b-linked Man is branched by two additional a-linked Man residues, one at the 3 position and one at the 6 position.[MT] term_xref : synonymns : function : disease_associations : wikipedia : essentials_of_glycobiology : hierarchy : notes :

Test

term (main_entry) : trimannosyl core

term_in_sentence : This glycoengineered H. polymorpha strain produced glycoproteins mainly containing trimannosyl core N-glycan (Man(3)GlcNAc(2)), which is the common core backbone of various human-type N-glycans.[PMID:18320567]

publication : 18320567|27629418|26514868|26821880|2477227|6213618|31747570|29273674|31064325|1291063|28353332|1421754|29666272|11421342|15648688|28179475|28903882|27189951|9455915|22768188|9254048|8721739|2249985|22933239|25629585|24489949|2981047|11067815|1729985|1710649|16672288|2719668|19003000|23025485|22500028|10409642|1325461|23136055|23085445|21656680|22448293|22132163|1425696|20696712|18056652|15084511|18633282|15814299

definition : A glycan that constitutes the core structure common to all high-mannose, complex, or hybrid N-glycans.  The trimannosyl core composition is Man3 GlcNAc2 and includes a chitobiose at the reducing terminal which is extended by a single b-linked Man residue.  The b-linked Man is branched by two additional a-linked Man residues, one at the 3 position and one at the 6 position.[MT]

term_xref :

synonymns :

function :

disease_associations :

wikipedia :

essentials_of_glycobiology :

hierarchy :

notes :