GlyGen and Foundation for Advanced Education in the Sciences (FAES) 2024 Workshop

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BIOF-GLYC 031 - Unraveling the Interplay of Genes, Proteins, and Glycans through Bioinformatics

Course Description Academic Programs at the NIH (FAES) and the GlyGen team is pleased to offer a one day, in-person, workshop at the National Institutes of Health, Bethesda campus on June 10, 2024.

Overview

The workshop will introduce participants to “GlycoBioInformatics Tools” and provide hands on exercises on GlyGen: Computational and Informatics Resources for Glycoscience.

The workshop is comprised of two sessions. In the morning, the instructors will share an overview of glycobiology and glycomics and will explore common bioinformatics tools that are used to analyze genes, proteins and glycans. In the afternoon, you will be guided by the instructors on how to use GlyGen and explore a variety of functions through hands-on exercises.

This workshop will be team taught by the GlyGen Team.

Agenda

Morning Session (Lecture)

A bioinformatics approach to studying genes, proteins and glycans. Glycobiology - What are glycans? Importance of glycans in health and disease Common bioinformatic tools to analyze genes, proteins and glycans How to find them Overview of glycomics tools (predication, mass spec, cartoon, etc.) Structure and use of common knowledgebases and tools that can be used to explore protein and glycan function Where to find them Overview about Glycomics and GlycoProteomics databases/knowledge bases Teaser: What is GlyGen

Lunch break

Afternoon Session (Hands-On)

  • GlyGen: Find glycans and proteins

Search glycan →List page → Details page Search protein → List page → Details page

  • GlyGen: Understanding subsumption
  • GlyGen: Glycosylation

Search protein by glycosylation Filtering on list pages Browsing glycosylation

  • GlyGen: Exploring sites

Sequence viewer Protvista Site search

  • GlyGen: Super search and other searches
  • Sandbox: Enzymes and pathways
  • GlyGen: Tools

Mapper Blast Sequence Lookup Motif Wiki

  • Open Question Session
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