History

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GlyGen History

  • William (Will) York (CCRC, University of Georgia, Athens) and Raja Mazumder (The George Washington University), along with their team members, founded GlyGen.
  • Raja and Will each wrote separate NIH R34 grants in 2015 for planning a glycoinformatics resource. Both were independently funded. They collaborated and jointly submitted the GlyGen proposal as Principal Investigators (PIs).
  • Raja's planning grant was titled GlycoCentral: Glycobiology Data and Tool Integration with Genes, Proteins, and Lipids (grant # 1R34GM116252), while Will's grant was named GlySpace: An Integrated Infrastructure for Glycoinformatics (grant # 1R34GM116258).
  • In 2016, during the planning phase, Will and Raja organized a use case gathering workshop at George Washington University (GW), bringing together worldwide experts from the glyco, genomics, and biocuration communities. They gathered over 100 use cases to guide the project.
  • Working with Rene Ranzinger and Nathan Edwards, they came up with the name "GlyGen" and developed the content for the first GlyGen U01 proposal, incorporating insights from collected use cases.
  • The GlyGen NIH U01 proposal was submitted by Will and Raja as joint Principal Investigators (PIs) and was funded under the grant under grant #1U01GM125267.
  • Following Will’s retirement, Michael (Mike) Tiemeyer assumed his role. In the current GlyGen Phase 2 (NIH R24, 1R24GM146616-01), Raja and Mike serve as Principal Investigators (PIs), with Rene Ranzinger (CCRC, University of Georgia, Athens) and Robel Kahsay (The George Washington University) as Co-Investigators.
  • Nathan Edwards (Georgetown University), Maria Martin (EBI), and Vijay Shanker (University of Delaware) contribute as sub-award investigators.