Glycan Structure Dictionary
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Glycan Structure Dictionary (GSD) contains terms commonly used to describe glycan structural features in publications. The glycan structure terms are primarily sourced via automatic and manual literature mining as well as from other bioinformatics databases. The Glycan Structure Dictionary is a work in progress and the terms are updated regularly to include the new term(s) and annotations. On this Wiki page the Glycan Structure Dictionary terms are listed by term name (alphabetically) and also by glycan dictionary accessions. To submit new terms go to section Glycan Structure Dictionary#Submit new terms. Contact https://www.glygen.org/contact-us/ to report any issues.
Please cite use of Glycan Structure Dictionary with: Vora J, Navelkar R, Vijay-Shanker K, Edwards N, Martinez K, Ding X, Wang T, Su P, Ross K, Lisacek F, Hayes C, Kahsay R, Ranzinger R, Tiemeyer M, Mazumder R. The glycan structure dictionary-a dictionary describing commonly used glycan structure terms. Glycobiology. 2023 Feb 17:cwad014. doi: 10.1093/glycob/cwad014. PMID: 36799723.
Terms (by Term Name)
2,6-Branched O-mannose
term (main_entry) : 2,6-Branched O-mannose
glycan_dictionary_accession : GSD000001
glytoucan_accession : G06953DR
term_in_sentence : Collectively, these results strongly suggest that GnT-IX may be a novel beta1,6-N-acetylglucosaminyltransferase that is responsible for the formation of the 2,6-branched structure in the brain O-mannosyl glycan.[PMID:14617637]
publication : 14617637|10469154
definition : (2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-5-acetamido-6-[[(2R,3S,4S,5S,6S)-5-[(2S,3R,4R,5S,6R)-3-acetamido-5-[(2S,3R,4S,5S,6R)-4-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,6-trihydroxyoxan-2-yl]methoxy]-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:157265]
term_xref : CHEBI:157265|GlycoMotif:GGM.000056|GTC:G06953DR
synonyms : 5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2→3)-beta-D-galacto-hexopyranosyl-(1→4)-2-acetamido-2-deoxy-beta-D-gluco-hexopyranosyl-(1→2)-[5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2→3)-beta-D-galacto-hexopyranosyl-(1→4)-2-acetamido-2-deoxy-beta-D-gluco-hexopyranosyl-(1→6)]-alpha-D-manno-hexopyranose|NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)]a-Man
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
2,6-sialyl-Sulfo-LN
term (main_entry) : 2,6-sialyl-Sulfo-LN
glycan_dictionary_accession : GSD000002
glytoucan_accession : G41145LF
term_in_sentence : The alpha2-6-sialylated 6-sulfo-LacNAc determinant defined by the antibody was significantly expressed on a majority of normal human peripheral B-lymphocytes as well as follicular B-lymphocytes in peripheral lymph nodes.[PMID:17728258]
publication : 17728258
definition :
term_xref : GlycoMotif:GGM.000026|GTC:G41145LF
synonyms : 6-sialyl-6-sulfo LN
function : B-cell interaction with blood vessels and trafficking[PMID: 17728258]
disease_associations :
wikipedia :
essentials_of_glycobiology :
2-Fucosyl-GD1b
term (main_entry) : 2-Fucosyl-GD1b
glycan_dictionary_accession : GSD000003
glytoucan_accession : G67383AR
term_in_sentence : They were fucosyl-Gv., fucoSyl-GDlb, and two uni que fucogangliosides having GMl or GOlb bas ic structure containing a substituent with the blood group B determinant. [PMID:3654655]
publication : 3654655
definition : (2S,4S,5R,6R)-5-Acetamido-6-[(1S,2R)-2-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-1,3-dihydroxypropyl]-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxyoxane-2-carboxylic acid.[CHEBI:156680]
term_xref : CHEBI:156680|GlycoMotif:GGM.000103|GTC:G67383AR
synonyms : 6-deoxy-alpha-L-galacto-hexopyranosyl-(1→2)-beta-D-galacto-hexopyranosyl-(1→3)-2-acetamido-2-deoxy-beta-D-galacto-hexopyranosyl-(1→4)-[5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2→8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2→3)]-beta-D-galacto-hexopyranosyl-(1→4)-D-gluco-hexopyranose|Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
2-Fucosyl-GM1
term (main_entry) : 2-Fucosyl-GM1
glycan_dictionary_accession : GSD000004
glytoucan_accession : G56526JU
term_in_sentence : These glycolipid products were identified as asialo-Gs.., GM h and fucosyl-Gq, by comparison with authentic glycolipid samples.[PMID:3654655]
publication : 3654655
definition : (2S,4S,5R,6R)-5-Acetamido-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:151476]
term_xref : KEGG:G12241|CHEBI:151476|CID:91849786|GlycoMotif:GGM.000101|GTC:G56526JU
synonyms : Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc|6-deoxy-alpha-L-galacto-hexopyranosyl-(1→2)-beta-D-galacto-hexopyranosyl-(1→3)-2-acetamido-2-deoxy-beta-D-galacto-hexopyranosyl-(1→4)-[5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid-(2→3)]-beta-D-galacto-hexopyranosyl-(1→4)-D-gluco-hexopyranose
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
3-Sialyl-LN (type 2)
term (main_entry) : 3-Sialyl-LN (type 2)
glycan_dictionary_accession : GSD000005
glytoucan_accession : G10203DW
term_in_sentence : Using new crystal structures, we also provide the atomic resolution basis for the differential recognition of 3′ and 6′SiaLacNAc1–4 (with the Galβ1–4 linkage known as Type 2 backbone16; Scheme 1) by TgMIC1-MARR, and make comparisons with the Type 1 chain isomer of 3′SiaLacNAc1–4 (designated 3′SiaLacNAc1–3).[PMID:19593815]
publication : 19593815|15659615|2414279|8586620|2111348|23747419
definition : A linear amino trisaccharide consisting of α-neuraminyl, β-D-galactosyl and N-acetyl-D-glucosamine residues linked in a (2→3) and (1→4) sequence.[CHEBI:52472]
term_xref : GTC:G10203DW|KEGG:G00253|SugarBind_Ligand:109|GlycoEpitope:EP0314|CHEBI:52472|GlycoMotif:GGM.000034
synonyms :
function :
disease_associations : Chronic gastritis[SugarBind_Ligand:109]|Toxoplasmosis[SugarBind_Ligand:109]|Peptic ulcers[SugarBind_Ligand:109]|Gastric cancer[SugarBind_Ligand:109]
wikipedia :
essentials_of_glycobiology :
3'-Sulfo-Lewis a
term (main_entry) : 3'-Sulfo-Lewis a
glycan_dictionary_accession : GSD000006
glytoucan_accession : G78706CK
term_in_sentence : A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes.[PMID:11504739]
publication : 11504739|17499486|17691854|12944557|19394320|7534477|11604107|28025252|9061363|9878545|11918697|24239607|28628803|25339106|21400496|17998215|12626387|11425799|12219077|10955596|9453593
definition : A branched amino trisaccharide consisting of N-acetylglucosamine having a fucosyl residue attached at the 4-position via an α-linkage and a 3-sulfated galactosyl residue attached at the 3-position via a β-linkage.[CHEBI:65149]
term_xref : GTC:G78706CK|GlycoEpitope:EP0009|CID:5289352|GlycoMotif:GGM.000030
synonyms : 3'-Sulfo-Lea|SuLe(a)|3'-sulpho-Le(a)|3-O-sulfo-Le(A)|3'-Sulfo Le^a|3'-Sulfo Lea|3'-Sulfo Lewis a
function : SO3-3-Gal and the SO3-3-Lea blood group antigen bound to H.pylori.[GlycoEpitope:EP0009]
disease_associations :
wikipedia :
essentials_of_glycobiology :
3'-Sulfo-Lewis x
term (main_entry) : 3'-Sulfo-Lewis x
glycan_dictionary_accession : GSD000007
glytoucan_accession : G12295TB
term_in_sentence : A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes.[PMID:11504739]
publication : 11504739|20695481|8688428|10536036|12770775|11352731|9784103|9022803
definition : An amino trisaccharide that consists of N-acetyl-β-D-glucosamine having an α-L-fucosyl residue attached at position 3 and a 3-sulfated β-D-galactosyl residue attached at position 4; β-D-Galp3S-(1→4)-[α-L-Fucp-(1→3)]-D-GlcpNAc in which the configuration at the anomeric centre of the reducing-end residue is β. [CHEBI:65171]
term_xref : GTC:G12295TB|GlycoEpitope:EP0013|CID:5289353|CHEBI:65171|GlycoMotif:GGM.000029
synonyms : 3'-sulfo-Le(x)|3'-Sulfo Lewis x|3'-sulfo Le^x|3'-sulfo Lex
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
6,6'-bisSulfo-Lewis x
term (main_entry) : 6,6'-bisSulfo-Lewis x
glycan_dictionary_accession : GSD000008
glytoucan_accession : G00659GQ
term_in_sentence : Comparison of the reactivity pattern of HEV with the reactivity of the pure 6-sulfo, 6'-sulfo, or 6,6'-bissulfo sialyl Lewis X determinant with hitherto known anti-sialyl Lewis X antibodies strongly suggested 6-sulfo sialyl Lewis X to be the best candidate for the major sulfated sialyl Lewis X determinant on HEV, followed by 6,6'-bissulfo sialyl Lewis X, whereas 6'-sulfo sialyl Lewis X was unlikely. [PMID:9556613]
publication : 19756298|14593101|15175329|14568956|12163379|11919403|11520459|10728707|10200296|10528213|9712885|9556613|9456330|9556613|9257857|9164959|9015359|8958810|7560094|7485559|7538131|8161542|7684905
definition : (2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-5-acetamido-6-hydroxy-2-(sulfooxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(sulfooxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:146095]
term_xref : GlycoEpitope:EP0016|CHEBI:146095|GlycoMotif:GGM.000028|GTC:G00659GQ
synonyms : 6,6'-DiSulfo Sialyl Lewis x|6,6-bisSulfo-Lewis x (6,60-bissulfo Lewis x )|6,6'- Disulfo Sialyl Lewis x|6,6'-bisSulfo-Lewis x|6,6'-bissulfo Lex|6,6'-Disulfo Sialyl Lewis x|6,6'-bissulfo Le^x
function : lymphocyte homing[GlycoEpitope:EP0016]
disease_associations :
wikipedia :
essentials_of_glycobiology :
6-Sialyl-GalNAc
term (main_entry) : 6-Sialyl-GalNAc
glycan_dictionary_accession : GSD000009
glytoucan_accession : G08371CD
term_in_sentence : mmunohistochemical distributions of carbohydrate antigens based on the type 2 chain in normal as well as fetal and neoplastic tissues of human gastrointestinal tract were investigated with a monoclonal antibody (MAb) H11 (specific for type 2 chain) alone and in combination with the two MAbs MSG15 (for alpha 2----6 sialylated type 2 chain) and IB9 (for the alpha 2----6 sialylated type 2 chain and glycoproteins having NeuAc alpha 2----6Gal-NAc), and 188C1 (for short- and long-chain Lex antigens) and FH2 (for the long-chain Lex antigen). [PMID: 1618643]
publication : 1618643|6194157
definition : An amino disaccharide composed of N-acetylneuraminic acid and 2-(acetylamino)-2-deoxy-D-galactopyranose residues joined by an (α-2→6) glycosidic bond.[CHEBI:146820]
term_xref : GlycoEpitope:EP0352|KEGG:G00455|KEGG:G10625|CHEBI:146820|CID:11409652|GlycoMotif:GGM.000035|GTC:G08371CD
synonyms : Sialyl Tn antigen|6-Sialyl-GalNAc|6-Sialyl LN|6-Sialyl LN (type 1)|6-Sialyl LN (type 2)
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
6-Sulfo LacNac
term (main_entry) : 6-Sulfo LacNac
glycan_dictionary_accession : GSD000010
glytoucan_accession : G13157WZ
term_in_sentence : In the search for an additional marker to better dissect the two subsets we have explored the marker 6-sulfo LacNAc (slan).[PMID:31572354]
publication : 31572354|31191513|29977237|29900053|30984181|28732748|26510404|28769928|31154896|27541644|25262889|26155414|28499587|27086951|27315572|26162403|26391152|31730025|12354382|27318477|23879812|25340085|24682513|21377044|21098395|18942710|23559493|23890755|22643330|23460612|23402811|22890025|19589615|32939325|20210806|17616642|22907335|16782032|22188261|21283706|29875315|32413173|19546436|19384158|1429720|30519676
definition : An oligosaccharide sulfate that is N-acetyllactosamine in which the hydroxy group at position 6 of the N-acetylglucosamine ring has been converted into its hydrogen sulfate derivative.[CHEBI:148005]
term_xref : GlycoEpitope:EP0141|GTC:G13157WZ|CID:10322152|CHEBI:148005
synonyms : 6-Sulfo LacNAc
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
6-Sulfo Sialyl Lewis x
term (main_entry) : 6-Sulfo Sialyl Lewis x
glycan_dictionary_accession : GSD000188
glytoucan_accession : G80722US
term_in_sentence : The cognate ligands for L-selectin possess the unusual sulfated tetrasaccharide epitope 6-sulfo sialyl Lewis x (Siaalpha2-->3Galbeta1-->4[Fucalpha1-->3][SO(3)-->6]GlcNAc).[PMID:11331001]
publication : 11331001|2288521|26137907|9400621|9556613|15972893|9015359|22691873|18652681|9722682|10435581|19359410|15228275|18250165|10536036|17944600|10460836|27993973|19149511|19150806|17172261|17142960|27956273|7578028|22260995|24519996|21596021|21982762|21775439|17334369|9710564|14593101|16227985|11895802|22750968|15157883|19067429
definition :
term_xref : GlycoMotif:GGM.000027|GlycoEpitope:EP0015|CID:70698321|CHEBI:71628
synonyms : 6-sulfo SLex|6-Sulfo-sialyl Lewis x|6-sulfo SLe^x
function : lymphocyte homing[GlycoEpitope:EP0015]
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 34|Chapter 35
6'-Sulfo Sialyl Lewis x
term (main_entry) : 6'-Sulfo Sialyl Lewis x
glycan_dictionary_accession : GSD000011
glytoucan_accession : G00672PE
term_in_sentence : Studies using sulfotransferase-deficient mice showed that 6-sulfo sialyl Lewis X (6-sulfo sLe(x)), a major ligand for L-selectin that is expressed on the high endothelial venules (HEVs), plays critical roles in lymphocyte homing to the peripheral lymph nodes.[PMID:2288521]
publication : 2288521|26137907|9400621|32744401|9556613|15972893|9015359|22691873|18652681|9722682|10435581|19458105|19359410|15228275|18250165|10536036|17944600|10460836|27993973|19149511|19150806|17172261|17142960|27956273|7578028|22260995|24519996|21596021|21982762|21775439|17334369|9710564|14593101|16227985|11895802|22750968|15157883|19067429
definition : A branched amino tetrasaccharide comprised of a trisaccharide chain of N-acetyl-α-neuraminic acid, 6-O-sulfo-β-D-glactose and N-acetyl-β-D-glucosamine residues linked sequentially (2→3) and (1→4), to the GlcNAC residue of which is also linked (1→3) an α-L-fucose residue.[CHEBI:71558]
term_xref : GlycoMotif:GGM.000025|GTC:G00672PE|CID:70698387|GlycoEpitope:EP0014|CHEBI:71558|SugarBind_Ligand:128
synonyms : 6'-sulfated sialyl Lewis x-|6'-sulfo-sLe(x)|Su-SaiLex|Su-Slex|6'-Sulfo-sialyl Lewis x
function : lymphocyte homing[GlycoEpitope:EP0014]
disease_associations : Influenza[SugarBind_Ligand:128]
wikipedia :
essentials_of_glycobiology : Chapter 14
9-O-Acetyl GD3
term (main_entry) : 9-O-Acetyl GD3
glycan_dictionary_accession : GSD000012
glytoucan_accession : G74121RX
term_in_sentence : To determine whether 9-O-acetyl GD3 (acGD3) has a general antiapoptotic potential, the apoptosis-sensitive Jurkat cell line and an apoptosis-sensitive variant of the cell line Molt-4 were preincubated with micromolar concentrations of acGD3 and then treated with inducers of apoptosis.[PMID:16432837]
publication : 16432837|21507905|17512674|21930212|18194438|20739294|3216430|14724245|31373393|7558412|11273644|17385751|30694652|22894715|12973826|7859075|9749956|9874495|12486096|1989525|25330147|23478187|21807667|8486686|11465673|9511990|29270199|9268945|25045067|21618115|16434401|12493756|2302705|2198284|2685488|9328574|4055789|10096568|1644805|2582447
definition :
term_xref : GTC:G74121RX|GlycoEpitope:EP0064|CID:91852520|GlycoMotif:GGM.000093
synonyms : acGD3|9-O-Acetylated GD3|9-O-Acetyl-GD3|9-O-Ac-GD3|CD60b
function :
disease_associations : pancreas cancer[GlycoEpitope:EP0064]
wikipedia :
essentials_of_glycobiology :
9-O-Acetyl sialic acid
term (main_entry) : 9-O-Acetyl sialic acid
glycan_dictionary_accession : GSD000013
glytoucan_accession : G47325QT
term_in_sentence : Levels of 9-O-acetyl sialic acid provide a distinct way to define progenitors and thus facilitate the study of hematopoietic differentiation.[PMID:31411667]
publication : 31411667|27936566|2509478|10049046|1826463
definition : N-acetyl-9-O-acetyl-alpha-neuraminic acid is a member of the class of N-acetylneuraminic acids that is alpha-neuraminic acid which has acetylated on N-5 and O-9. It has functional parent alpha-neuraminic acid.[CHEBI:84941]
term_xref : GTC:G47325QT|GlycoEpitope:EP0065|CID:13991612|CHEBI:84941
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 15
Alpha-gal antigen
term (main_entry) : Alpha-gal antigen
glycan_dictionary_accession : GSD000016
glytoucan_accession : G24432YB
term_in_sentence : Therefore, alpha-gal antigen might be eliminated after a prolonged culture, when using human cells.[PMID:31267683]
publication : 31267683|29319188|29481481|26140655|30337555|29235434|22909134|28280265|7532618|23390540|22808845|29898796|22262104|31267683|25430953|22993330|23578170|21043478|28294277|27696820|15814276|17991149|25577211|30578545|19895316|28068870|18546155|32907757|26485996|9771839|12042247|27567275|12131678|23114154|19184002|29577591|29806570|15638815|21118731
definition : A glycosylgalactose that consists of β-D-galactose having an α-D-galactosyl residue at the 3-position.[CHEBI:62330]
term_xref : GTC:G24432YB|GlycoMotif:GGM.000015|CID:52939789|CHEBI:62330
synonyms : a-Gal antigen
function : Has role as a carbohydrate allergen, epitope or an antigen.[CHEBI:62330]
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 14
Alpha-galactosylceramide
term (main_entry) : Alpha-galactosylceramide
glycan_dictionary_accession : GSD000017
glytoucan_accession :
term_in_sentence : From 24 weeks of age, NZB/NZW F1 mice were injected with alpha-galactosylceramide (α-GalCer) or vehicle once a week for four weeks.[PMID:29844470]
publication : 29844470|30421497|31575643|30745361|30953000|30556652|29617191|31689579|28872688|30195979|29940370|27004737|27198610|28743554|31649670|31484693|25752588|21383248|25527277|30821985|28947140|31244823|29311431|30803854|29576533|26101952|31213291|22412194|28067024|31199716|27354638|24465013|25445911|28120096|15630427|27803187|21392534|31075434|22683545|26191196|26811064|23935988|28623127|24913977|25434827|23420533|21839133|25314062|27325450|23874157
definition :
term_xref :
synonyms : alpha-GalCer|alpha-GalCers|α-GalCer
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Asialo-biantennary
term (main_entry) : Asialo-biantennary
glycan_dictionary_accession : GSD000018
glytoucan_accession :
term_in_sentence : Typical crystallizable fragment (Fc) glycans attached to the CH2 domain in therapeutic monoclonal antibodies (mAbs) are core-fucosylated and asialo-biantennary complex-type glycans, e.g., G2F (full galactosylation), G1aF (terminal galactosylation on the Man α1-6 arm), G1bF (terminal galactosylation on the Man α1-3 arm), and G0F (non-galactosylation).[PMID:30990348]
publication : 30990348|17645671|20959391|18615430|16945378|2065054|3084472|2386787|22911097|24692304|17013932|7513972|6626573|10835250|9684342
definition :
term_xref :
synonyms : asialo diantennary
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Asialo-GM1
term (main_entry) : Asialo-GM1
glycan_dictionary_accession : GSD000019
glytoucan_accession : G21856LC
term_in_sentence : We compared the lateral structure of giant unilamellar vesicles (GUVs) composed of three pseudo binary mixtures of different glycosphingolipid (GSL), i.e. sulfatide, asialo-GM1 or GM1, with POPC.[PMID:29106974]
publication : 29106974|3418980|26975993|8613364|9288228|26710925|24922516|6839313|1828259|2581667|8210226|25062498|9671150|10377092|6171919|3093429|6652964|3124753|8905612|18788941|1467432|8225593|2083955|6171918|7806377|1802483|7927723|9209156|21174147|2584393|12137200|6175621|2936802|8610366|21490162|1548508|3486908|26453755|7910939|3756909|1639356|3259967|2443562|3112077|2572647|25137483|2168971|6950172
definition :
term_xref : GlycoMotif:GGM.000099|GTC:G21856LC|CID:10169040|GlycoEpitope:EP0047|CHEBI:59216
synonyms : as-GM1|GA-1|Gangliotetraosylceramide|GgO4|Gg4|Asialo-GM1a|ganglio-N-tetraosylceramide
function :
disease_associations : Pleuropneumonia[SugarBind_Ligand:2]|Porcine fibrinohemorrhagic necrotizing pleuropneumonia[SugarBind_Ligand:2]|Actinomycosis[SugarBind_Ligand:2]|Lazy leukocyte syndrome[SugarBind_Ligand:2]|Pertussis[SugarBind_Ligand:2]|Cutaneous lesions[SugarBind_Ligand:2]|Melioidosis[SugarBind_Ligand:2]|Candidiasis[SugarBind_Ligand:2]|Taiwan acute respiratory agent[SugarBind_Ligand:2]|Trachoma[SugarBind_Ligand:2]|Cystitis[SugarBind_Ligand:2]|Chronic gastritis[SugarBind_Ligand:2]|Peptic ulcers[SugarBind_Ligand:2]|Gastric cancer[SugarBind_Ligand:2]|Klebsiella pneumonia infection[SugarBind_Ligand:2]|Pneumonia[SugarBind_Ligand:2]|Legionnaires' disease[SugarBind_Ligand:2]|Gonorrhea[SugarBind_Ligand:2]|Gastroenteritis[SugarBind_Ligand:2]|Toxoplasmosis[SugarBind_Ligand:2]|Plague[SugarBind_Ligand:2]|Diarrhea[SugarBind_Ligand:2]
wikipedia :
essentials_of_glycobiology :
B-GD1B
term (main_entry) : B-GD1B
glycan_dictionary_accession : GSD000020
glytoucan_accession : G72557NR
term_in_sentence : The Molecular Modelling and 10 ns MD simulation of Botulinum Neuro Toxin/B-GD1A and BoNT/B-GD1B complex revealed that this toxin can interact with GD1A in the single binding mode and with GD1B in two binding modes.[PMID:22929125]
publication : 27956354|22929125
definition :
term_xref : GlycoMotif:GGM.000104|GTC:G72557NR|CID:91847819|KEGG:G01803|CHEBI:153361
synonyms : B-GD1b
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
B-GM1
term (main_entry) : B-GM1
glycan_dictionary_accession : GSD000021
glytoucan_accession : G11485ID
term_in_sentence : The contribution of GM3 and GD3, which accounted for 95% of the ganglioside sialic acid at birth, decreased during the first 3 weeks of life. GM1, fucosyl-GM1, and B-GM1 were not detected at birth. [PMID: 3680254]
publication : 3680254
definition : (2S,4S,5R,6R)-5-Acetamido-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-acetamido-5-hydroxy-4-[(2R,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-4-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.[CHEBI:147588]
term_xref : GlycoMotif:GGM.000102|GTC:G11485ID|CID:91853157|CHEBI:147588|SugarBind_Ligand:181
synonyms :
function :
disease_associations : Cholera[SugarBind_Ligand:181]
wikipedia :
essentials_of_glycobiology : Chapter 37
Biantennary
term (main_entry) : Biantennary
glycan_dictionary_accession : GSD000022
glytoucan_accession :
term_in_sentence : We found an efficient isopropylidenation reaction that selectively protects the terminal Gal-3,4-OH of a biantennary complex-type nonasaccharide isolated from a natural source.[PMID:29249147]
publication : 29249147|24991291|29409839|30325416|18083109|26926155|16715395|12634321|24211369|23115267|31907993|23360551|20861009|33142198|11442281|18687680|15680603|31888963|14686925|15819890|22530754|22098756|9346821|19341309|18529007|20580347|11784152|7773775|10913832|8547276|10463590|9404657|30525457|15316280|8068637|3881425|6425277|8576139|29956878|1576211|11129583|30421263|8069634|30973186|16704415|21612260|29806066|29443078
definition : Type of N-linked glycan in which two antenna are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). Each antenna can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:Glossary]
term_xref :
synonyms : diantennary
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 9
Biantennary complex
term (main_entry) : Biantennary complex
glycan_dictionary_accession : GSD000023
glytoucan_accession :
term_in_sentence : The crystal structure of Pterocarpus angolensis lectin is determined in its ligand-free state, in complex with the fucosylated biantennary complex type decasaccharide NA2F, and in complex with a series of smaller oligosaccharide constituents of NA2F.[PMID:16704415]
publication : 16704415|3731182|26747427|32597008|6626573|29249147|28597152|25045879|30325416|12634321|31888963|26926155|23360551|33142198|9404657|29956878|14686925|18687680|11784152|7773775|22530754|20580347|22098756|21612260|6425277|7691595|26780731|16285669|15819890|3924097|30448401|8547276|17049014|29408873
definition : A complex N-glycan that has two branches attached to the non-reducing terminal Man residues of the trimannosyl core. . Each branch is initiated with a GlcNAc and can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [CHEBI:156251]
term_xref : CHEBI:156251
synonyms : diantennary complex type
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Bisecting GlcNac
term (main_entry) : Bisecting GlcNac
glycan_dictionary_accession : GSD000024
glytoucan_accession :
term_in_sentence : The presence of a bisecting GlcNAc and the occurrence of alpha 2-6-linked Neu5Ac in the most abundant N-glycans, are new features for hCG-beta.[PMID:1374031]
publication : 1374031|29909448|29274553|32719771|22476631|31375533|26467158|27429195|20816221|26109616|30542567|30144245|25727145|29593568|32612952|9006930|19508951|16000695|32597008|19053837|22530754|30405631|19940114|32719549|9560299|29655002|10589784|29959030|20661133|9061364|31065629|20395209|29549127|30305426|29632412|24108122|24282611|27821068|14686925|10816579|25032906|30025558|9661906|8542600|31585439|29699572|27443163|30315103|23808883|18812317|19776078
definition : The bisecting GlcNAc is a modification of hybrid or complex N-linked glycans in which a single GlcNAc is added to the 3 position of the b-linked Man found in the trimannosyl core structure. The modification is catalyzed by beta 1,4-N-acetylglucosaminyltransferase III (GlcNAcT-III) or MGAT3 (E.C. 2.4.1.144). The addition of a bisecting GlcNAc on a hybrid or trimmed hybrid glycan prevents the subsequent action of N-glycan branching glycosyltransferases GlcNAcT-IV and GlcNAcT-V, but GlcNAcT3 can add a bisecting GlcNAc to the products of these enzymes. [PMID: 22476631]
term_xref : SID:163312364|KEGG:G13066
synonyms :
function : The bisecting GlcNAc of N-glycans regulates cellular signaling and tumor progression through modulating N-glycan/galectin interactions.[PMID: 22476631]Inhibits growth factor signaling and retards mammary tumor progression[PMID: 20395209]Integrin-mediated cell adhesion [PMID: 20816221]Important in fertilization and fetal development, neuritogenesis, immune tolerance, immunoglobulin G (IgG)[PMID: 32719771]
disease_associations : mammary tumor.[PMID: 20395209]
wikipedia :
essentials_of_glycobiology : Chapter 9
Bisialo-biantennary
term (main_entry) : Bisialo-biantennary
glycan_dictionary_accession : GSD000025
glytoucan_accession :
term_in_sentence : Using anion-exchange liquid chromatography mapping of the oligosaccharide units cleaved from the proteins by glycopeptidase F, compared with elution positions of standard oligosaccharide structures, coupled with monosaccharide compositional analysis, we find that the human plasma protein contained only bisialo-biantennary complex-type carbohydrate and asialo-biantennary complex carbohydrate, confirming earlier work published by this laboratory.
publication : 2386787|2065054
definition : A binantennary glycan with sialic acid residues as non-reducing terminal residues on both antennae.
term_xref :
synonyms : disialo biantennary|disialo diantennary|disialylated biantennary|disialylated diantennary
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Bisialo-biantennary complex-type
term (main_entry) : Bisialo-biantennary complex-type
glycan_dictionary_accession : GSD000026
glytoucan_accession :
term_in_sentence : Using anion-exchange liquid chromatography mapping of the oligosaccharide units cleaved from the proteins by glycopeptidase F , compared with elution positions of standard oligosaccharide structures , coupled with monosaccharide compositional analysis, we find that the human plasma protein contained only bisialo-biantennary complex-type carbohydrate and asialo-biantennary complex carbohydrate , confirming earlier work published by this laboratory.[PMID:2386787]
publication : 2386787|26966183
definition : A binantennary glycan with sialic acid residues as non-reducing terminal residues on both antennae.
term_xref :
synonyms : Fully sialylated biantennary N-glycan
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 25
Blood group A trisaccharide
term (main_entry) : Blood group A trisaccharide
glycan_dictionary_accession : GSD000029
glytoucan_accession : G00066MO
term_in_sentence : A readily detectable carbohydrate in the urine of two siblings with neuronal ceroid lipofuscinosis was found to be the blood group A trisaccharide.[PMID:7249368]
publication : 19582848|7249368|8774717|2749874|28771597|30619340|2122121|11886841|2991755|12588002|3149698|7048329|7015594|10359132|8724140|1418679|1446307
definition : A branched amino trisaccharide consisting of β-D-galactose having an α-L-fucosyl residue at the 2-position and an N-acetyl-α-D-galactosaminyl residue at the 3-position.[CHEBI:61012]
term_xref : GlycoEpitope:EP0255|GTC:G00066MO|CID:49852448|KEGG:G10638|CHEBI:61012
synonyms : blood group A trisaccharide|blood group A type 1 trisaccharide
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group A (Type 1)
term (main_entry) : Blood group A (Type 1)
glycan_dictionary_accession : GSD000030
glytoucan_accession : G66163TI
term_in_sentence : he basis of blood group A(1) and A(2) phenotypes has been debated for many decades, and still the chemical basis is unresolved. [PMID:19121199]
publication : 10942408|19121199
definition : An α-D-GalpNAc-(1→3)-[α-L-Fucp-(1→2)]-β-D-Galp-(1→3)-D-GlcpNAc having β-configuration at the reducing end anomeric centre.[CHEBI:62485]
term_xref : GlycoMotif:GGM.000044|GTC:G66163TI|GlycoEpitope:EP0256|CID:53262359|CHEBI:62485
synonyms : Blood group A(1)|blood group A antigen type 1
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group A (Type 1) - Lewis b
term (main_entry) : Blood group A (Type 1) - Lewis b
glycan_dictionary_accession : GSD000190
glytoucan_accession : G97501MA
term_in_sentence : Ten monoclonal antibodies and one lectin were used to study the localization and distribution of Blood Group ABH, type 1 chain (Lewis a, Lewis b) and type 2 chain (H-2, Y) antigens in 22 cases of normal uterine cervix, with known ABO and Lewis phenotype and secretor status.[PMID:2247887]
publication : 2247887|19756298|4041428|5686860
definition : A branched amino pentasaccharide consisting of the linear trisaccharide N-acetyl-α-D-galactosaminyl-(1→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosamine having α-L-fucosyl residues attached at position 2 of the galactose and position 4 of the glucosamine. Corresponds to a partial structure of blood group A type 1 oligosaccharide.[CHEBI:62988]
term_xref : GlycoMotif:GGM.000047|CID:53477630|CHEBI:62988|GlycoEpitope:EP0260
synonyms : Blood Group A Type 1 (difucosyl)|ALe^b|A-Leb|A-Le^b|A Lewis b
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group A (Type 2)
term (main_entry) : Blood group A (Type 2)
glycan_dictionary_accession : GSD000014
glytoucan_accession : G74353FF
term_in_sentence : One hybridoma antibody (AH16), obtained on immunization with human gastric cancer cell MKN45, was directed to the blood group A determinant carried by both type 1 and type 2 chains. [PMID:6583282]
publication : 27196314|6583282|8340255|18701592|21901093|2413709|8036794|1615929|3285099
definition : A branched amino tetrasaccharide comprising N-acetyl-β-D-glucosamine at the reducing end with a N-acetyl-α-D-galactosaminyl-(1→3)-[α-L-fucosyl-(1→2)]-β-D-galactosyl moiety attached at the 4-position.[CHEBI:62486]
term_xref : GTC:G74353FF|CID:53262376|GlycoEpitope:EP0257|CHEBI:62486|GlycoMotif:GGM.000038
synonyms : A Type 2|Blood group A type 2 chain
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 14
Blood group A (Type 2) - Lewis y
term (main_entry) : Blood group A (Type 2) - Lewis y
glycan_dictionary_accession : GSD000027
glytoucan_accession : G54826OZ
term_in_sentence : Monoclonal antibodies defining blood group A variants with difucosyl type 1 chain (ALeb) and difucosyl type 2 chain (ALey).[PMID:2417620]
publication : 2417620
definition : A branched amino pentasaccharide consisting of the linear trisaccharide N-acetyl-α-D-galactosaminyl-(1→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine having α-L-fucosyl residues attached at position 2 of the galactose and position 3 of the glucosamine. Corresponds to a partial structure of blood group A type 2 oligosaccharide.[CHEBI:62990]
term_xref : GlycoEpitope:EP0261|GTC:G54826OZ|CHEBI:62990|CID:5289011|GlycoMotif:GGM.000039
synonyms : Blood group A (type 2) (A-Ley)|Blood Group A Type 2 (difucosyl)|Blood group A (type 2) (A-Lewis Y)|A-Ley|A-Le^y
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group A (Type 3)
term (main_entry) : Blood group A (Type 3)
glycan_dictionary_accession : GSD000187
glytoucan_accession : G99315PE
term_in_sentence :
publication : 7800218|17998569|19756298|3191504
definition :
term_xref : GlycoMotif:GGM.000011|GTC:G99315PE
synonyms : A type 3 antigen|blood group A type 3|A antigen (type 3)
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 14
Blood group A (Type 4)
term (main_entry) : Blood group A (Type 4)
glycan_dictionary_accession : GSD000028
glytoucan_accession : G37830TX
term_in_sentence : Moreover, we have found that αGal, but not αGalNAc, is a weak binder itself for DC-SIGN, which could endow an additional binding mode for the blood group B antigen, but not for blood group A.[PMID:31283166]
publication : 7800218|7521740|2458640|31283166
definition :
term_xref : GlycoMotif:GGM.000088|GTC:G37830TX|CID:91852258|KEGG:G00474|CHEBI:150159|SugarBind_Ligand:48
synonyms :
function :
disease_associations : Pyelonephritis[SugarBind_Ligand:48]|Acute cystitis[SugarBind_Ligand:48]
wikipedia :
essentials_of_glycobiology :
Blood group A1 (Type 3)
term (main_entry) : Blood group A1 (Type 3)
glycan_dictionary_accession : GSD000031
glytoucan_accession : G44060QH
term_in_sentence : The structure is essentially a repetitive A epitope attached to type 2 chain and is hereby called type 3 chain A. [PMID:2579390]
publication : 2579390|19756298
definition : A branched amino heptasaccharide made up from two repeating (1→3)-linked N-acetyl-α-D-galactosaminyl-(1→3)-[α-L-fucosyl-(1→2)]-β-D-galactosyl units that are in turn joined to an N-acetyl-β-D-glucosamine residue via a (1→4)-linkage.[CHEBI:85665]
term_xref : GTC:G44060QH|CHEBI:85665|CID:91825676|GlycoMotif:GGM.000040
synonyms : Blood group A1 (type 3)|Blood Group A1
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group A2 (A-associated H type 3)
term (main_entry) : Blood group A2 (A-associated H type 3)
glycan_dictionary_accession : GSD000032
glytoucan_accession : G62735WZ
term_in_sentence : The H NMR spectrum of the associated H antigen (type 3 chain H) was characterized by the unusual presence of three n-anomeric resonances ('CJ'.~ = 3-4 Hz) in addition to five resonances from @-anomeric protons ("J1:2 = 7-9 Hz).[PMID: 3944091]
publication : 3944091|29000000|28658771
definition : A branched amino hexasaccharide in which an α-L-fucosyl-(1→2)-β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-(1→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine linear pentasaccharide carries at the galactose residue proximal to the reducing end a second α-L-fucosyl residue via a (1→2) linkage.[CHEBI:152543]
term_xref : CHEBI:152543|CID:91852328|GlycoMotif:GGM.000041|GTC:G62735WZ
synonyms : Blood Group A2|Fuca1-2Galb1-3GalNAca1-3(Fuca1-2)Galb1-4GlcNAcb|Fuc(a1-2)Gal(b1-3)GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)b-GlcNAc|Fucalpha1-2Galbeta1-3GalNAcalpha1-3(Fucalpha1-2)Galbeta1-4GlcNAcbeta|6-deoxy-alpha-L-galacto-hexopyranosyl-(1→2)-beta-D-galacto-hexopyranosyl-(1→3)-2-acetamido-2-deoxy-alpha-D-galacto-hexopyranosyl-(1→3)-[6-deoxy-alpha-L-galacto-hexopyranosyl-(1→2)]-beta-D-galacto-hexopyranosyl-(1→4)-2-acetamido-2-deoxy-beta-D-gluco-hexopyranose|6-deoxy-alpha-L-galactopyranosyl-(1→2)-[6-deoxy-alpha-L-galactopyranosyl-(1→2)-beta-D-galactopyranosyl-(1→3)-2-acetamido-2-deoxy-alpha-D-galactopyranosyl-(1→3)]-beta-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-beta-D-glucopyranose
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group B (Type 1)
term (main_entry) : Blood group B (Type 1)
glycan_dictionary_accession : GSD000033
glytoucan_accession : G31734OS
term_in_sentence : The minimal binding epitope was identified as the blood group H type 1 determinant (Fucα2Galβ3GlcNAc), while an optimal binding epitope was created by addition of the terminal α3-linked galactose or N-acetylgalactosamine of the blood group B type 1 determinant (Galα3(Fucα2)Galβ3GlcNAc) and the blood group A type 1 determinant (GalNAcα3(Fucα2)-Galβ3GlcNAc). [PMID: 19208633]
publication : 18701592|24749871|19387828|19208633|29562255
definition : α-D-Galp-(1→3)-[α-L-Fucp-(1→2)]-β-D-Galp-(1→3)-β-D-GlcpNAc with β configuration at the anomeric carbon of the GlcNAc residue at the reducing end.[CHEBI:63242]
term_xref : GlycoMotif:GGM.000043|GTC:G31734OS|CID:56927779|CHEBI:63242
synonyms : blood group B type 1 tetrasaccharide
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group B (Type 1) - Lewis b
term (main_entry) : Blood group B (Type 1) - Lewis b
glycan_dictionary_accession : GSD000189
glytoucan_accession : G89208KM
term_in_sentence : Ten monoclonal antibodies and one lectin were used to study the localization and distribution of Blood Group ABH, type 1 chain (Lewis a, Lewis b) and type 2 chain (H-2, Y) antigens in 22 cases of normal uterine cervix, with known ABO and Lewis phenotype and secretor status. [PMID:2247887]
publication : 2247887|19756298|30831115
definition :
term_xref : GlycoMotif:GGM.000046
synonyms : Blood Group B, type 1 chain (Lewis b)|B-Leb|B-Le^b
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group B (Type 2)
term (main_entry) : Blood group B (Type 2)
glycan_dictionary_accession : GSD000034
glytoucan_accession : G34881WK
term_in_sentence : The detection of a B type 2 determinant is the first chemical evidence for the presence of an autologous difucosyl blood group B type 2 antigen in human adenocarcinoma cells.[PMID:2432062]
publication : 2432062|27196314|18701592
definition :
term_xref : GlycoMotif:GGM.000037|GTC:G34881WK|GlycoEpitope:EP0262
synonyms : blood group B type 2
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group B (Type 4)
term (main_entry) : Blood group B (Type 4)
glycan_dictionary_accession : GSD000035
glytoucan_accession : G25216QA
term_in_sentence : The blood group B type-4 heptaglycosylceramide is a minor blood group B structure in human B kidneys in contrast to the corresponding A type-4 compound in A kidneys.[PMID:1390942]
publication : 1390942|1841684
definition :
term_xref : GlycoMotif:GGM.000087|GTC:G25216QA
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group H (Type 1)
term (main_entry) : Blood group H (Type 1)
glycan_dictionary_accession : GSD000036
glytoucan_accession : G00294TN
term_in_sentence : Blood group H type 1 [Fuc alpha (1,2)Gal beta (1,3)GlcNAc beta-->] is known as the precursor structure of the blood group determinant, Lewis b [Fuc alpha (1,2)Gal beta (1,3)(Fuc alpha (1,4))GlcNAc beta-->].[PMID:7718581]
publication : 7718581|6309836|19208633|27431816|2432062|24219248|6352465|8499478|3348768|3718924
definition :
term_xref : GTC:G00294TN|GlycoMotif:GGM.000042|SugarBind_Ligand:153
synonyms : H type 1
function :
disease_associations : Gastroenteritis[SugarBind_Ligand:153]
wikipedia :
essentials_of_glycobiology :
Blood group H (Type 2)
term (main_entry) : Blood group H (Type 2)
glycan_dictionary_accession : GSD000037
glytoucan_accession : G70519XK
term_in_sentence : We have examined the immunohistochemical distribution of H Type 1 and of H Type 2 substances of the ABO blood group system in human submandibular gland using either of the two anti-H monoclonal antibodies MAb 1E3 and MAb 3A5. MAb 3A5 was specific for H Type 2, and MAb 1E3 reacted with each of H Type 1-H Type 4 artificial antigens.[PMID:9405495]
publication : 9405495|8082855|6177241|3944092|21406562|2410664|8731502|6203846|2238560|
definition :
term_xref : GTC:G70519XK|GlycoMotif:GGM.000036
synonyms : Blood group H (type 2)|H type 2|H type 2 chain|H type 2 antigen|type 2 chain H|blood group H type II
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Blood group H (Type 2) - Lewis y
term (main_entry) : Blood group H (Type 2) - Lewis y
glycan_dictionary_accession : GSD000038
glytoucan_accession : G00052MO
term_in_sentence : The fucosylated histo-blood group antigens H type 2 (blood group O, CD173) and Lewis Y (CD174) are expressed on CD34+ hematopoietic progenitors but absent on mature lymphocytes.[PMID: 11479278]
publication : 11479278
definition : A branched amino tetrasaccharide consisting of N-acetyl-β-D-glucosamine at the reducing end having an α-L-fucosyl residue attached at the 3-position and an α-L-fucosyl-(1→2)-β-D-galactosyl moiety attached at the 4-position. A cancer-associated tetrasaccharide antigen which constitutes the core structure recognised by therapeutic antibody BR96. Conformational restriction around the GlcNAc residue is a key feature of its structure.[CHEBI:59045]
term_xref : GTC:G00052MO|GlycoEpitope:EP0018|CID:45266908|CHEBI:59045|GlycoMotif:GGM.000045
synonyms : Lewis y|Blood group H (type 2) (Ley)|Lewis b (Leb)|Lewis a|Lewis b (Lewis b)|Blood group H (type 2) - Lewis y|H-Ley|H-Le^y|Lewis Y|H-Ley|H-Le^y|Lewis Y
function : The expression of the fucosylated histo-blood group antigen CD174 in CD34+ hematopoietic progenitor cells and down-regulation of FUT1 in mature lymphocytes may be important factors influencing the homing process of hematopoietic stem cells to the bone marrow.[GlycoEpitope:EP0018]
disease_associations : AIDS/acquired immune deficiency syndrome[GlycoEpitope:EP0018]|cholangiocarcinoma[GlycoEpitope:EP0018]|hepatocellular carcinoma[GlycoEpitope:EP0018]|Inappropriate tissue distribution of Ley blood-group antigens was observed in CCs(cholangiocarcinomas) and, much less frequently, in HCCs(hepatocellular carcinomas).[GlycoEpitope:EP0018]|Ley determinant is highly expressed in human immunodeficiency virus (HIV)-infected T cell lines and in CD3+ peripheral mature T cells of patients with acquired immune deficiency syndrome (AIDS) or with AIDS-related complex (ARC).[GlycoEpitope:EP0018]
wikipedia :
essentials_of_glycobiology : Chapter 14
Blood group H (Type 3)
term (main_entry) : Blood group H (Type 3)
glycan_dictionary_accession : GSD000105
glytoucan_accession : G94435QH
term_in_sentence : One particular lambody, VLRB.aGPA.23, was shown by glycan array analysis to be selective for the blood group H type 3 trisaccharide (BG-H3, Fucα1-2Galβ1-3GalNAcα), aGPA, and TFα (Galβ1-3GalNAcα), with affinity constants of 0.2, 1, and 8 nM, respectively.[PMID:23030719]
publication : 23030719|20466654|1563908|3944092|11218748|11101633|18842005|27550195|2469783|2433836|23118206|8445257|2664192|3063304
definition :
term_xref : GlycoMotif:GGM.000010|GTC:G94435QH
synonyms : H type 3|H antigen (type 3)|Type 3 chain H
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 11
Blood group H (Type 4)
term (main_entry) : Blood group H (Type 4)
glycan_dictionary_accession : GSD000039
glytoucan_accession : G98465JN
term_in_sentence : In addition, the blood group H type 4 chain structure was present together with Le(a) and Le(b) compounds.[PMID:1841684]
publication : 11261842|1841684|11101633|9405495
definition : An amino hexasaccharide consisting of α-L-fucose, β-D-galactose, N-acetyl-α-D-galactosamine, α-D-galactose, β-D-galactose and β-D-glucose residues joined in sequence with (1→2)-, (1→3)-, (1→3)-, (1→4)- and (1→4)-linkages, respectively.[CHEBI:65245]
term_xref : GlycoMotif:GGM.000086|GTC:G98465JN|CID:10260428|SugarBind_Ligand:61|CHEBI:65245
synonyms :
function :
disease_associations : Pyelonephritis[SugarBind_Ligand:61]
wikipedia :
essentials_of_glycobiology :
C2-O-sLex
term (main_entry) : C2-O-sLex
glycan_dictionary_accession : GSD000040
glytoucan_accession : G97345NY
term_in_sentence : PSGL-1 lacks 6-sulfo-sLex but contains sulfated tyrosine residues (Tyr-SO3)at positions 46, 48, and 51 and sLex in a core 2-based O-glycan (C2-O-sLex) on Thr at position 57.[PMID:12736247]
publication : 12736247|19267921|21283832|15596301|17072011
definition : A seven-membered branched galactosamine oligosaccharide that consists of a branched tetrasaccharide unit α-Neu5Ac-(2→3)-β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc, attached by a glycosidic linkage to position 6 of the GalNAc residue of the trisaccharide α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-D-GalNAc.[CHEBI:65192]
term_xref : GlycoMotif:GGM.000053|GTC:G97345NY|CID:91860725|KEGG:G10899|CHEBI:155160
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Ceramide dihexosyl sulfate
term (main_entry) : Ceramide dihexosyl sulfate
glycan_dictionary_accession : GSD000041
glytoucan_accession : G04416BG
term_in_sentence : Although it has been reported that ceramide dihexosyl sulfate is present in human kidney, it is unlikely that it is present in equine kidney.[PMID:818074]
publication : 818074
definition : A sulfatide with two hexose moieties (glucose and galactose) has been isolated from human kidney (Martensson E, Acta Chem Scand 1963, 17, 1174). Equimolar amounts of ceramide, glucose, galactose, and sulfate are found in the molecule. The sulfate group is esterified, as in sulfatides, with carbon 3 of the galactose moiety. The linkage between galactose and glucose is identical to lactose (b-1-4). Its fatty acid composition is similar to that of sulfatides. [http://cyberlipid.gerli.com/description/complex-lipids/glycolipids/glycosphingolipids/sulfosphingolipids/]
term_xref : GTC:G04416BG|GlycoMotif:GGM.000065
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Chondroitin sulfate
term (main_entry) : Chondroitin sulfate
glycan_dictionary_accession : GSD000043
glytoucan_accession :
term_in_sentence : The industrial production of chondroitin sulfate (CS) uses animal tissue sources as raw material derived from different terrestrial or marine species of animals.[PMID: 31013685]
publication : 31013685|27526113|27194526|26980567|28847361|24413804|29891297|29600622|25129732|31317901|29181550|31250530|22265655|25756648|29402610|17928217|20236040|28091940|30824935|26572336|31207331|21110089|30599999|20399897|27226567|19388612|23186102|31494830|28982096|30241863|30295666|25366475|20521042|29456007|31304829|18661362|28576008|29494632|30016441|26906924|24861964|23774590|31887904|31339761|12512856|26957048|29625000
definition : Any of a class of 10—60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues.[CHEBI:37397]
term_xref : CHEBI:37397|CID:24766
synonyms : chondroitin polysulfate|chondroitin sulfate|chondroitin sulfates|chondroitin sulfuric acid|chondroitin sulphate|Chondroitinsulfate
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Chondroitin sulfate/dermatan sulfate
term (main_entry) : Chondroitin sulfate/dermatan sulfate
glycan_dictionary_accession : GSD000184
glytoucan_accession :
term_in_sentence : Heparan sulfate (HS) and chondroitin sulfate/dermatan sulfate (CS/DS) proteoglycans are heavily glycosylated proteins, crucial for animal development and homeostasis. [PMID:35192612]
publication : 35192612|35425970
definition :
term_xref :
synonyms : CS/DS|chondroitin/dermatan sulfate
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
cisGM1
term (main_entry) : cisGM1
glycan_dictionary_accession : GSD000044
glytoucan_accession : G03277YI
term_in_sentence : Macrophage ganglioside patterns dramatically increase in complexity when murine peritoneal macrophages are stimulated in vivo with the appearance of the sialidase-sensitive monosialoganglioside GM1b (cisGM1) as a major component.[PMID: 9455923]
publication : 9455923
definition : A member of the class of neuraminic acids that is neuraminic acid attached in sequence to β-D-galactopyranosyl, 2-acetamido-2-deoxy-β-D-galactopyranosyl, β-D-galactopyranosyl, and β-D-gucoopyranose units by (2→3), (1→3), (1→4), and (1→4) glycosidic linkages, respectively. It corresponds to the carbohydrate portion of ganglioside GM1b.[CHEBI:145580]
term_xref : GlycoMotif:GGM.000100|GTC:G03277YI|CID:91850212|CHEBI:145580|GlycoEpitope:EP0048|SugarBind_Ligand:92|KEGG:G00125
synonyms : GM1b
function :
disease_associations : Influenza[SugarBind_Ligand:92]
wikipedia :
essentials_of_glycobiology : Chapter 23
Complex-type N-glycans
term (main_entry) : Complex-type N-glycans
glycan_dictionary_accession : GSD000045
glytoucan_accession :
term_in_sentence : In this study, 32 new complex-type glycans are characterized containing the Le(x), Le(Y), and sialyl-Le(x) determinants, the bloodgroup A and H antigens, as well as the ALe(Y) determinant.[PMID:10988252]
publication : 29902282|29212795|29343819|27705835|26745022|18399796|16825488|21964725|15864431|22890903|12417032|28039392|19426135|30253927|16794314|19806620|22975979|25931033|15201278|1912963419129628|24032650|22530754|31021709|30973186|28091941|23115339|20829342|27304954|29090617|21802690|29725121|30471292|16581187|26098720|31080188|1930135|31888963|30844485|24014058|11129583
definition : Type of N-linked glycan in which at least two antenna are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). Each antenna can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues.
term_xref :
synonyms :
function : Involved in protein stability.[PMID:12417032]
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 17
Core 1
term (main_entry) : Core 1
glycan_dictionary_accession : GSD000186
glytoucan_accession : G00031MO
term_in_sentence : O-glycans are initiated by the addition of GalNAc to serine or threonine (via the ppGalNAcT family of glycosyltransferases), forming the Tn antigen (GalNAcα-O-Ser/Thr), which is used to generate the core 1 structure (Galβ1,3GalNAcα-O-Ser/Thr) on which most complex and branched O-glycans are derived. [PMID:31645367]
publication : 31645367|32297877
definition :
term_xref : GTC:G00031MO|GlycoMotif:GGM.001005
synonyms : C1G
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Core 2
term (main_entry) : Core 2
glycan_dictionary_accession : GSD000046
glytoucan_accession : G00033MO
term_in_sentence : To investigate the biological roles of core 2 O-glycans, we produced and characterized mice deficient in one or more of the three known glycosyltransferases that generate core 2 O-glycans (C2GnT1, C2GnT2, and C2GnT3).[PMID: 19349303]
publication : 19349303|30315106|23640779|26677400
definition : The trisaccharide β-D-Gal-(1→3)-[β-D-GlcNAc-(1→6)]-D-GalNAc with α configuration at the anomeric centre of the N-acetylglucosamine residue at the reducing end.[CHEBI:62158]
term_xref : GTC:G00033MO|CID:52921656|CHEBI:62158
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Core 3
term (main_entry) : Core 3
glycan_dictionary_accession : GSD000047
glytoucan_accession : G00035MO
term_in_sentence : Mechanically, we revealed that mucin-type core 3 O-glycan was synthesized at the membrane-tethered MUC1 N terminus because of core 3 synthase expression in colon cancer cells.[PMID: 28745318]
publication : 28745318|27259834|27143302|
definition : An amino disaccharide comprising an N-acetyl-β-D-glucosamine residue linked (1→3) to an N-acetyl-β-D-galactosamine residue at the reducing end.[CHEBI:71344]
term_xref : GTC:G00035MO|CID:25061208|CHEBI:71344
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 9
Core 4
term (main_entry) : Core 4
glycan_dictionary_accession : GSD000048
glytoucan_accession : G00037MO
term_in_sentence : The results confirm the predicted existence of a beta1,6GlcNAc-transferase that functions in both core 2 and core 4 O-glycan branch formation.[PMID: 9988682]
publication : 9988682|10747980|
definition : A branched amino trisaccharide comprising an N -acetyl-α-D-galactosamine residue at the reducing end, to which are (1→3)- and (1→6)-linked two N -acetyl-α-D-glucosamine residues.[CHEBI:71341]
term_xref : GTC:G00037MO| CID:25229562|CHEBI:71341
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 8
Core-fucosylated
term (main_entry) : Core-fucosylated
glycan_dictionary_accession : GSD000049
glytoucan_accession : G78059CC
term_in_sentence : The approach was validated for selective capture and analysis of core fucosylated N-glycans present in complex glycan mixtures derived from mammalian serum IgG.[PMID:27678371]
publication : 27678371|26514868|15538974|24914453|17049014|32078267|31268672|28674882|29956878|27798819|32044029|30962950|31548313|30907281|29090617|29571940|28800497|27629418|29733746|31623829|28768188|26897254|31451706|26514868|29427759|28982386|26587313|30940702|15538974|31249452|27282921|31229844|30445455|31325506|24732908|29209018|26965517|28609658|24914453|25573275|17049014|19218400|27012207|27139574|32078267|25861849|32561391|21374780|31669139|25732060|29408166|31268672|30472795|30614075|19003000|25664929
definition : Modification of the N-glycan core structure with fucose moiety attached at the innermost GlcNAc by FUT8 enzyme. Core Fuc is found on paucimannose, hybrid and complex type N-glycans. [https://doi.org/10.1016/bs.acr.2014.11.006].
term_xref : GTC:G78059CC|CID:70679232|CHEBI:70967|CHEBI:156499
synonyms : Core Fuc|6-linked Fuc|Fuca6 to chitobiose core|a6-linked Fuc|a1-6 Fuc|Fuca6 to chitobiose core|Fuc a1-6 to chitobiose core|Fuca6 to internal GlcNAc|Fuc a1-6 to internal GlcNAc
function : Required for signaling through TCR [PMID: 29434598]|VGF, PDGFr, and EGFr and TGFbeta receptor dysregulation in Fut8 KO mice [PMID:17132494]|IgG-Fcg receptor interactions destabilized by core Fuc [PMID:29062024]
disease_associations : Emphysema|systemic lupus erythematosuslung cancer|autoimmunity|tumor metastasis
wikipedia :
essentials_of_glycobiology : Chapter 8
Core-fucosylated biantennary
term (main_entry) : Core-fucosylated biantennary
glycan_dictionary_accession : GSD000050
glytoucan_accession : G78059CC
term_in_sentence : The IFN-alpha14c N-glycans were shown to exhibit core-fucosylated biantennary glycans , with about 10% carrying an additional alpha1,3-linked fucose unit at the antennae.[PMID:9654101]
publication : 9654101|15819890|28263871|26763099|22256781|23681398|25855029|10529240|26544759|8206921|33149259|8547276
definition : A biantennary glycan with two GlcNAc branches linked to the core and fucosylation on the core GlcNAc.
term_xref : GTC:G78059CC|CID:70679232|CHEBI:70967|CHEBI:156499
synonyms : core-fucosylated diantennary
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 8
Core-fucosylated biantennary complex-type
term (main_entry) : Core-fucosylated biantennary complex-type
glycan_dictionary_accession : GSD000051
glytoucan_accession : G78059CC
term_in_sentence : The oligosaccharide structure at Asn(32 ) is a mixture of the monosialo and asialo forms of a core fucosylated biantennary complex-type oligosaccharide.[PMID:10731668]
publication : 10731668
definition : A biantennary complex glycan with two GlcNAc branches linked to the core and fucosylation on the core GlcNAc.
term_xref : GTC:G78059CC|CID:70679232|CHEBI:70967|CHEBI:156499
synonyms : core fucosylated diantennary complex-type
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Cyclic sialyl 6-sulfo Lewis x
term (main_entry) : Cyclic sialyl 6-sulfo Lewis x
glycan_dictionary_accession : GSD000052
glytoucan_accession : G11148DZ
term_in_sentence : Stimulation of the sialyl 6-sulfo Lewis X-positive colon cancer cell line with a calcium ionophore ionomycin markedly reduced sialyl 6-sulfo Lewis X and induced cyclic sialyl 6-sulfo Lewis X expression.[PMID:10728707]
publication : 10728707|31222115|9990070|23088960
definition :
term_xref : GlycoEpitope:EP0017|CID:91858084|CHEBI:147484
synonyms :
function : The accumulated intracellular cyclic sialyl 6-sulfo Lex determinant may function as a dormant pool of selectin ligands.[GlycoEpitope:EP0017]
disease_associations :
wikipedia :
essentials_of_glycobiology :
Cytolipin R
term (main_entry) : Cytolipin R
glycan_dictionary_accession : GSD000053
glytoucan_accession : G57710SU
term_in_sentence : The reaction can be inhibited completely by pure cytolipin R showing that (a) immune hemolysis can be mediated through lipid determinants in the membrane, and (b) that cytolipin R determinants are present in the intact erythrocyte membrane and exposed on the surface.[PMID:4110375]
publication : 893368|4375678|51702|186204|4110375|5068000|24174198|6072378|389925|7054174
definition : A ceramide tetrahexoside isolated from rat lymphosarcoma. The structure of cytolipin R to be N-acetylgalactosaminyl(beta1-->3)galactosyl(alpha1-->3) galactosyl(beta1-->4)glucosyl ceramide.[PMID:5068000]
term_xref : GlycoMotif:GGM.000083|GTC:G57710SU|CID:91855936|KEGG:G00392|CHEBI:152175|SugarBind_Ligand:17
synonyms :
function :
disease_associations : Actinomycosis[SugarBind_Ligand:17]
wikipedia :
essentials_of_glycobiology :
Dermatan sulfate
term (main_entry) : Dermatan sulfate
glycan_dictionary_accession : GSD000054
glytoucan_accession :
term_in_sentence : By utilizing sophisticated separation methods followed by compositional analysis, domain mapping, and tandem mass spectrometry coupled with analysis by a modified genetic algorithm approach, the structural motif for the decorin dermatan sulfate chain was determined.[PMID:29111696]
publication : 27526113|29111696|29891297|26164146|30869126|7789716|8597249|12512856|31250530|17928217|12213784|27226567|31455633|28091940|19075609|31071403|15078125|18661328|20581662|17239765|15749837|2777747|20632047|8930750|7762784|31006321|26876822|1522290|131009|26986023|8161353|15315969|12543559|30637950|2525357|18156656|9692613|9200333|19661164|2299256|16075147|1126924|9774430|8537360|15563459|21077227|23275130|17137817|6447930|6209270
definition : Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated β1→4-linked L-iduronyl-(α1→3)-N-acetyl-D-galactosamine units.[CHEBI:18376]
term_xref : CHEBI:18376|CID:32756
synonyms : beta-Heparin|Chondroitin sulfate B|Dermatan L-iduronate
function : Wound healing[Essentials of Glycobiology:Chapter 7]|maintain the structure of the dermis.[Essentials of Glycobiology:Chapter 41]
disease_associations :
wikipedia :
essentials_of_glycobiology :
Desialylated
term (main_entry) : Desialylated
glycan_dictionary_accession : GSD000055
glytoucan_accession :
term_in_sentence : Furthermore, we found no evidence for "desialylated" apoB100 glycans in any of the samples analyzed.[PMID:11588155]
publication : 30015642|26168491|29492899|31774586|32321401|23780974|7600681|18045697|1450583|4137057|28911304|27562992|29950245|31978220|2408573|8612720|10910970|27195066|1434544|22175031|24517196|29794068|30101537|18972200|1478792|4440781|21229239|30844664|31351722|31330845|1872910
definition : A glycan from which sialyl groups have been removed. [https://en.wiktionary.org/wiki/desialylated]
term_xref :
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Desialylated tetrasaccharide
term (main_entry) : Desialylated tetrasaccharide
glycan_dictionary_accession : GSD000056
glytoucan_accession :
term_in_sentence : The structures of a desialylated tetrasaccharide , two monosialylated trisaccharides , and five other minor products were defined.[PMID:8384526]
publication : 8384526
definition : A tetrasachharide (four branches) glycan from which sialyl groups have been removed.
term_xref :
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 17
Difucosylated tetra-antennary N-glycans
term (main_entry) : Difucosylated tetra-antennary N-glycans
glycan_dictionary_accession : GSD000057
glytoucan_accession :
term_in_sentence : While fucosylated N-glycans derived from serum haptoglobin of patients with CP slightly increased, di-fucosylated tetra-antennary N-glycans were observed only at this site in PC patients, and were absent in the haptoglobin of normal controls and individuals with CP.[PMID:18214858]
publication : 18214858
definition : The tetra-antennary N-linked glycans that have four GlcNAc branches linked to the core and two fucose added.
term_xref :
synonyms :
function :
disease_associations : pancreatic cancer[PMID:18214858]
wikipedia :
essentials_of_glycobiology :
Dimeric Lewis x
term (main_entry) : Dimeric Lewis x
glycan_dictionary_accession : GSD000058
glytoucan_accession : G79535HZ
term_in_sentence : The carbohydrate antigen dimeric Lewis X (DimLex), which accumulates in colonic and liver adenocarcinomas, is a valuable target to develop anti-cancer therapeutics.[PMID:32957489]
publication : 32957489|31276881|12062524|15488731|1979361|8737237|17939723|7683631|11384108|11133015|17388629|15483381|12662048|3233598|18618154|21892456
definition : A six-membered glucosamine oligosaccharide consisting of two repeating units of β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc joined by a (1→3)-linkage.[CHEBI:61325]
term_xref : GTC:G79535HZ|GlycoEpitope:EP0093|CID:50909845|CHEBI:61325|GlycoMotif:GGM.000031
synonyms : DimLex^x|dimeric Le(x)|Lex-Lex|diLe(x)|Lewisx-Lewisx
function : cancer-associated antigen[GlycoEpitope:EP0093]
disease_associations : colonic cancer[GlycoEpitope:EP0093]|liver cancer[GlycoEpitope:EP0093]
wikipedia :
essentials_of_glycobiology : Chapter 14
Diphosphorylated Man6
term (main_entry) : Diphosphorylated Man6
glycan_dictionary_accession : GSD000059
glytoucan_accession : G54792LL
term_in_sentence : Here we report that the single-chain variable domain (scFv) M6P-1 is a unique antibody fragment with specificity for Man6P monosaccharide that, through an array-screening approach against a number of phosphorylated N-glycans, is shown to bind mono- and diphosphorylated Man6 and Man7 glycans that contain terminal αMan6P(1 → 2)αMan(1 → 3)αMan.[PMID:26503547]
publication : 26503547
definition :
term_xref : GTC:G54792LL|GlycoMotif:GGM.000054
synonyms : Diphosphorylated Man_6
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Disialosyl globopentaosylceramide
term (main_entry) : Disialosyl globopentaosylceramide
glycan_dictionary_accession : GSD000060
glytoucan_accession : G97932OH
term_in_sentence : Disialosyl globopentaosylceramide (DSGb5) is often expressed by renal cell carcinomas.[PMID:31339142]
publication : 31339142|24637536|25864532|27344728|12084983|32567311|28205070|20663960|18214042
definition : Disialosyl globopentaosylceramide (DSGb5) is a ganglioside originally isolated from tissue extracts of renal cell carcinoma (RCC) with metastasis.[PMID:28205070]
term_xref : GlycoMotif:GGM.000082|GTC:G97932OH|GlycoEpitope:EP0098|CID:91860287|KEGG:G00181|SugarBind_Ligand:57
synonyms : DSGb5|Disialosyl Gb5|V3NeuAcIV6NeuAc-Gb5Cer|Disialosylgalactosylgloboside
function : promotes metastasis[PMID:28205070]
disease_associations : prostate cancer[PMID:24637536]|renal cell carcinoma/RCC[GlycoEpitope:EP0098]|Pyelonephritis[SugarBind_Ligand:57]
wikipedia :
essentials_of_glycobiology :
Disialyl Gb5
term (main_entry) : Disialyl Gb5
glycan_dictionary_accession : GSD000061
glytoucan_accession : G97932OH
term_in_sentence : The major disialoganglioside antigen isolated from ACHN cells, showing specific reactivity with 5F3, was characterized unequivocally as disialosyl Gb5 (V(3)NeuAcIV(6)NeuAcGb5) by identification of the core structure as globopentaosylceramide (Gb5) after enzymatic and acid hydrolysis, and by 2-dimensional (1)H-NMR spectroscopy.[PMID: 12084983]
publication : 12084983
definition :
term_xref : GlycoEpitope:EP0098|GTC:G97932OH|CID:91860287|SugarBind_Ligand:57|KEGG:G00181
synonyms :
function :
disease_associations : renal cell carcinoma/RCC[GlycoEpitope:EP0098]|Pyelonephritis[SugarBind_Ligand:57]
wikipedia :
essentials_of_glycobiology :
Disialyl I
term (main_entry) : Disialyl I
glycan_dictionary_accession : GSD000062
glytoucan_accession : G54937EM
term_in_sentence : Here we present an example of promotion of binding of soluble-form FN from placenta or from hepatoma cells, having a specific carbohydrate epitope termed "disialyl-I," to K562 or VA13 cell surface in the presence of glycosphingolipid Gg3, which interacts specifically with disialyl-I[PMID:10640401]
publication : 10640401
definition :
term_xref : GlycoEpitope:EP0095|GTC:G54937EM|CID:91849523
synonyms : disialyl-I
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Disialyl Lewis a
term (main_entry) : Disialyl Lewis a
glycan_dictionary_accession : GSD000063
glytoucan_accession : G93400AK
term_in_sentence : Biosynthesis of disialyl Lewis a (Lea) was analyzed using previously cloned ST6GalNAc V and ST6GalNAc VI, which were responsible for the synthesis of alpha-series gangliosides.[PMID:12668675]
publication : 12668675|17760270|15231659|12668106|30716533|32050430|22467657
definition : Disialyl Lewis is a sialyl Lewis a with an additional sialic acid attached at the C-6 position of penultimate GlcNAc. [PMID:15231659]
term_xref : GTC:G93400AK |GlycoEpitope:EP0040|CID:91854138|CHEBI:155549
synonyms : disialyl Lea
function : The 2-3,2-6 disialyl Lea determinant on epithelial cells may play a role in protecting normal epithelial cells.[GlycoEpitope:EP0040]
disease_associations : Mucin antigen carrying 2-3 sialylated Le a antigen or 2-3, 2-6 disialylated Lc4 antigen in cancer patients had the lowest carbohydrate/protein ratio. Thus, the carbohydrate/protein ratio in the type 1 chain mucin antigens in sera of normal subjects is higher than that in sera of cancer patients.[GlycoEpitope:EP0040]
wikipedia :
essentials_of_glycobiology :
Disialyl T antigen
term (main_entry) : Disialyl T antigen
glycan_dictionary_accession : GSD000064
glytoucan_accession : G01614ZM
term_in_sentence : The most potent glycoside was disialyl T antigen (NeuAcalpha2-3Galbeta1-3[NeuAcalpha2-6]GalNAc-R), followed by 3-sialyl T antigen (NeuAcalpha2-3Galbeta1-3GalNAc-R), structures expressed on O-linked glycoproteins as well as on gangliosides.[PMID: 15701648]
publication : 29113555|17974963|33242079|12645620|15701648|26598643
definition : α-Neup5Ac-(2→6)-[α-Neup5Ac-(2→3)-β-D-Galp-(1→3)]-α-D-GalpNAc in which the anomeric configuration of the reducing-end N-acetyl-D-glucosamine residue is α.[CHEBI:71602]
term_xref : GlycoMotif:GGM.000014|GTC:G01614ZM|CID:70698317|CHEBI:71602|GlycoEpitope:EP0023|KEGG:G00027
synonyms : di-sialyl T antigen|disialyl-T antigen|disialylated T-antigen
function : associated with von Willebrand factor(VWF) plasma levels[GlycoEpitope:EP0023]
disease_associations :
wikipedia :
essentials_of_glycobiology :
Disialylated biantennary
term (main_entry) : Disialylated biantennary
glycan_dictionary_accession : GSD000065
glytoucan_accession :
term_in_sentence : FAB-MS, electrospray-mass spectrometry, and linkage analysis demonstrated that each monomer of rat CRP contained one oligosaccharide chain , predominantly a disialylated biantennary structure , attached to Asn-128.[PMID:8486673]
publication : 22426998|17171781|25022802|24812685|24780636|26582205|9499382|22978794|22594947|8486673|20356825|1634621|9244386|12966096|1472054|24243045|19579232|27943633
definition : A biantennary glycan with two GlcNAc branches linked to the core and the addition of two sialic acid residues.
term_xref :
synonyms : disialylated diantennary
function : appears in human transferrin[PMID: 24243045]|Appears in human apolipoprotein (apo) B-100.[PMID:2344297]
disease_associations : galactosemia.[PMID:9499382]
wikipedia :
essentials_of_glycobiology :
Disialylated biantennary complex-type
term (main_entry) : Disialylated biantennary complex-type
glycan_dictionary_accession : GSD000066
glytoucan_accession :
term_in_sentence : The glycan was shown to be a disialylated biantennary complex type oligosaccharide N-linked to 318 Asn.[PMID:11738084]
publication : 11738084|9499382|9244386|24243045|12966096|25124522|19371135
definition : A biantennary complex glycan with two GlcNAc branches linked to the core and the addition of two sialic acid residues.
term_xref :
synonyms :
function : appears in human transferrin[PMID:24243045]|Appears in human apolipoprotein (apo) B-100.[PMID:2344297]
disease_associations : galactosemia.[PMID:9499382]
wikipedia :
essentials_of_glycobiology :
Disialylated fucosylated
term (main_entry) : Disialylated fucosylated
glycan_dictionary_accession : GSD000067
glytoucan_accession :
term_in_sentence : Disialylated fucosylated and monosialylated non-fucosylated oligosaccharides were also identified.[PMID:17591618]
publication : 17591618
definition : A fucosylated glycan with two sialic acid components.
term_xref :
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 45
Forssman antigen
term (main_entry) : Forssman antigen
glycan_dictionary_accession : GSD000068
glytoucan_accession : G80062GG
term_in_sentence : Here we report the crystal structure of the complex between SLL-2 and Forssman antigen tetrasaccharide (GalNAcα1-3GalNAcβ1-3 Galα1-4 Galβ at 3.4 √Ö resolution.[PMID:28510705]
publication : 28510705|31933576|28134301|7021748|1802714|7512587|7747818|23325748|268649|31816281|22015168|4147161|2857159|6267170|7293775|13367419|20636540|10460829|23255552|2675268|18955372|7020692|31784953|4114942|31273262|6257673|7696847|1916901|11169215|48262|26022515|6175621|31404475|6983878|8381954|10431785|3257757|6792413|25039359
definition : A linear amino pentasaccharide comprising N-acetyl-α-D-galactosamine, N-acetyl-β-D-galactosamine, α-D-galactose, β-D-galactose and β-D-glucose residues linked sequentially (1→3), (1→3), (1→4) and (1→4).CHEBI:85789]
term_xref : GTC:G80062GG |GlycoEpitope:EP0037|CID91825690|CHEBI:85789
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 45
Forssman glycolipid
term (main_entry) : Forssman glycolipid
glycan_dictionary_accession : GSD000069
glytoucan_accession : G80062GG
term_in_sentence : Analysis of metabolically labeled glycolipids released into the apical and basal culture medium, either as shed membrane vesicles or in budding viruses, also demonstrated the presence of the Forssman glycolipid on both apical and basolateral membranes of polarized cells.[PMID:3040119]
publication : 3040119|268649|23240079|28134301|3495590|1138893|10460829|10506200|8855242|1955453|1933935|3355161|6773959|14573676|29898878|10431785|1747956|11214737|7423202|389939|3871816|6187373|16133832|469271|3753492|2695680|7037611|25703376|23798992|414913|1868069|7960243
definition : A linear amino pentasaccharide comprising N-acetyl-α-D-galactosamine, N-acetyl-β-D-galactosamine, α-D-galactose, β-D-galactose and β-D-glucose residues linked sequentially (1→3), (1→3), (1→4) and (1→4).[CHEBI:85789]
term_xref : GlycoMotif:GGM.000084|GTC:G80062GG|CID:91825690|KEGG:G00095|CHEBI:85789|GlycoEpitope:EP0037|SugarBind_Ligand:86
synonyms : Forssman antigen|Globopentosylceramide
function : an antigenic marker for a major subpopulation of macrophages from murine spleen and peripheral lymph nodes[PMID:3495590]
disease_associations : Pyelonephritis[SugarBind_Ligand:86]|Acute cystitis[SugarBind_Ligand:86]
wikipedia :
essentials_of_glycobiology : Chapter 45
Fucose-containing tetraantennary
term (main_entry) : Fucose-containing tetraantennary
glycan_dictionary_accession : GSD000070
glytoucan_accession :
term_in_sentence : The two major N-linked oligosaccharides of Namalwa EPO were fucose-containing tetraantennary and fucose-containing triantennary structures.[PMID:2550193]
publication : 2550193
definition : A tetraantennary glycan with four GlcNAc branches linked to the core and the addition of fucose.
term_xref :
synonyms :
function :
disease_associations :
wikipedia : https://en.wikipedia.org/wiki/Forssman_antigen
essentials_of_glycobiology : Chapter 14
Fucosyl GM1
term (main_entry) : Fucosyl GM1
glycan_dictionary_accession : GSD000071
glytoucan_accession : G91532KA
term_in_sentence : Unique localization of fucosyl GM1 implicates its possible role in cell adhesion and recognition in the nervous system.[PMID:8068725]
publication : 6619101|16880505|9089399|29789847|8068725|19556222|1660040|2420639|9076515|15926079|19555091|2541996|16211870|1336587|21174147|14967068|18923900|30021910|16941490|27070150|8305235|10602885|2645049|7993838|10537341|3002616|8336147|15447995|8905401|11714535|9260862|32228455|3315641|8076384|2317201|3680254|6403518
definition : A branched amino hexasaccharide consisting of the linear sequence α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-D-Glc having a Neu5Ac residue attached to the inner galactose via an α-(2→3) linkage.[CHEBI:62686]
term_xref : GTC:G91532KA |GlycoEpitope:EP0049|CID:53356699|CHEBI:62686
synonyms :
function :
disease_associations : small-cell lung cancer(SCLC)[GlycoEpitope:EP0049]|hepatoma[GlycoEpitope:EP0049]
wikipedia :
essentials_of_glycobiology :
Fucosylated asialo-biantennary
term (main_entry) : Fucosylated asialo-biantennary
glycan_dictionary_accession : GSD000072
glytoucan_accession :
term_in_sentence : We found that approximately 63% of the total N-linked oligosaccharides were of the complex type, with bisialo-biantennary (28%), asialo-biantennary (7%), fucosylated bisialo-biantennary (25%), and fucosylated asialo-biantennary (3%) oligosaccharides representing the major complex-type carbohydrate species.[PMID:2065054]
publication : 2065054|17013932
definition : Describing a biantennary oligosaccharide that has no sialic acid component but has fucose.
term_xref :
synonyms : fucosylated asialo-diantennary
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Fucosylated biantennary
term (main_entry) : Fucosylated biantennary
glycan_dictionary_accession : GSD000073
glytoucan_accession :
term_in_sentence : The profiles of the PSA N-glycans from the free and complexed molecules were quite similar to each other and consisted of fucosylated biantennary oligosaccharides as the major class.[PMID:17956937]
publication : 17956937|30525457|1933856
definition : a biantennary glycan with two GlcNAc branches linked to the core and the addition of fucose.
term_xref :
synonyms : fucosylated bisialo-diantennary
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Fucosylated bisialo-biantennary
term (main_entry) : Fucosylated bisialo-biantennary
glycan_dictionary_accession : GSD000074
glytoucan_accession :
term_in_sentence : We found that approximately 63% of the total N-linked oligosaccharides were of the complex type, with bisialo-biantennary (28%), asialo-biantennary (7%), fucosylated bisialo-biantennary (25%), and fucosylated asialo-biantennary (3%) oligosaccharides representing the major complex-type carbohydrate species.[PMID:2065054]
publication : 2065054
definition : Describing a biantennary oligosaccharide that has two sialic acid component and fucose added.
term_xref :
synonyms : Fucosylated biantennary
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Fucosylated LDN
term (main_entry) : Fucosylated LDN
glycan_dictionary_accession : GSD000075
glytoucan_accession : G02240AO
term_in_sentence : To date, oligomeric LDN and oligomeric fucosylated LDN (LDNF) have been found only on N-glycans from mammalian cells engineered to express Caenorhabditis elegansbeta4-GalNAc transferase and human alpha3-fucosyltransferase IX [Z. S. Kawar et al. (2005) J Biol Chem280, 12810-12819]. [PMID:16403022]
publication : 16403022|28151933|19545571|22448293
definition : An amino trisaccharide comprising an acetamido-β-D-galactose and an α-L-fucose attached to an acetamidoglucose by 1→4 and 1→3 linkages, respectively.[CHEBI:61864]
term_xref : GlycoMotif:GGM.000017|GTC:G02240AO|GlycoEpitope:EP0151|CID:52921591|CHEBI:61864|MeSH:C488538|KEGG:G01594
synonyms : LDNF|Fucosylated lacdiNAc|LDN-F|(GalNAc)1 (GlcNAc)1 (LFuc)1
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
Fucosylated N-glycans
term (main_entry) : Fucosylated N-glycans
glycan_dictionary_accession : GSD000076
glytoucan_accession :
term_in_sentence : Haptoglobin , an acute phase protein , has four potential N-glycosylation sites , although it remains unknown which site is responsible for the change in fucosylated N-glycans.[PMID:18214858]
publication : 18214858|31141660|26869352|29790113|31931062
definition : The fucose from GDP-fucose is transferred to N-linked glycans.
term_xref :
synonyms :
function :
disease_associations : pancreatic cancer.[PMID: 26869352]
wikipedia :
essentials_of_glycobiology :
Fucosylated triantennary
term (main_entry) : Fucosylated triantennary
glycan_dictionary_accession : GSD000077
glytoucan_accession :
term_in_sentence : Asn184 is only partially glycosylated and substituted by fucosylated triantennary and small amounts of diantennary N-acetyllactosaminic glycans.[PMID:2513186]
publication : 2513186|29642865|7679920|31110965|2551687|15051952|12943224
definition : A triantennary glycan with three GlcNAc branches linked to the core and the addition of fucose.
term_xref :
synonyms :
function : appears in human alpha-fetoprotein (AFP).[PMID: 7679920]
disease_associations : neoplastic diseases of the liver[PMID: 7679920 ]|hepatocellular carcinoma[PMID: 7679920].
wikipedia :
essentials_of_glycobiology : Chapter 43
Galabiosylceramide
term (main_entry) : Galabiosylceramide
glycan_dictionary_accession : GSD000078
glytoucan_accession : G67988RO
term_in_sentence : LacCer and its structural isomer, galabiosylceramide (Gb2, Galβ(1,4)Galβ-ceramide), are classified as ceramide dihexosides (CDH).[PMID:33360824]
publication : 33360824|29099167|25582508|2824515|4027258|32854306|32868283|31319156|29530250|27367163|2564247|27727434|10216186|10460829|24992926|23590301|15702404|1854798|14761135|3600200|8603914|8601603|1965141|17400502|3840690|15959771|7930586|7721812|17095952|2500499|3815386|8842706|10746023|3928791|3782065|6440894
definition : A disaccharide consisting of β-D-galactopyranose having a D-galactopyranosyl residue attached at the 4-position via an α-linkage.[CHEBI:59314]
term_xref : GlycoEpitope:EP0113|GTC:G67988RO|CID:5288350|KEGG:G00497|KEGG:G10645|CHEBI:59314
synonyms :
function :
disease_associations : tumor/lung[GlycoEpitope:EP0113]|tumor/gallbladder[GlycoEpitope:EP0113]|tumor/kidney[GlycoEpitope:EP0113]|tumor/pancreas[GlycoEpitope:EP0113]
wikipedia :
essentials_of_glycobiology :
Galactosylceramide
term (main_entry) : Galactosylceramide
glycan_dictionary_accession : GSD000079
glytoucan_accession : G65889KE
term_in_sentence : Galactosylceramide improved behavioral, neuropathological, and biochemical parameters in Cln3 Cln3 Δex7/8 mice, paving the way for effective therapy for CLN3 disease and use of serum ceramide as a potential biomarker to track impact of therapies.[PMID:31393621]
publication : 31393621|19941861|9883654|33006978|26735924|22032265|18035062|25129050|2802541|1761517|28660574|475780|2302222
definition :
term_xref : GTC:G65889KE|GlycoEpitope:EP0074|SugarBind_Ligand:1|GlycoMotif:GGM.000061
synonyms : GalCer|Galactocerebroside|LC
function :
disease_associations : Pleuropneumonia[SugarBind_Ligand:1]|Porcine fibrinohemorrhagic necrotizing pleuropneumonia[SugarBind_Ligand:1]|Lyme disease[SugarBind_Ligand:1]|Plague[SugarBind_Ligand:1]|Acquired immune deficiency syndrome[SugarBind_Ligand:1]
wikipedia :
essentials_of_glycobiology :
Galnac disialyl Lc4 (Hexasaccharide)
term (main_entry) : Galnac disialyl Lc4 (Hexasaccharide)
glycan_dictionary_accession : GSD000080
glytoucan_accession : G33532XU
term_in_sentence : Therefore, a new marker for prostate cancer is urgently required. We examined expression of a novel carbohydrate antigen, beta1,4-GalNAc-disialyl-Lc(4), defined by the monoclonal antibody RM2, in prostate cancer using 75 cases of radical prostatectomy specimens.[PMID: 12084983]
publication : 15704108|11278988|12084983|7509790
definition : (2R,4S,5R,6R)-5-Acetamido-2-[[(2R,3S,4R,5R,6S)-5-acetamido-4-[(2R,3R,4R,5S,6R)-4-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-5-[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-6-[(3R,4S,5S,6R)-2,3,5-trihydroxy-6-(hydroxymethyl)oxan-4-yl]oxyoxan-2-yl]methoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.[CID:91857945]
term_xref : GlycoEpitope:EP0097|GTC:G33532XU|CID:91857945|CHEBI:149360
synonyms :
function :
disease_associations : prostate cancer[GlycoEpitope:EP0097]|renal cell carcinoma/RCC[GlycoEpitope:EP0097]
wikipedia :
essentials_of_glycobiology :
Gb5
term (main_entry) : Gb5
glycan_dictionary_accession : GSD000081
glytoucan_accession : G99053DY
term_in_sentence : LnbB, a member of the glycoside hydrolase family 20 isolated from Bifidobacterium bifidum, was shown to release GNB from Gb5 and GA1 oligosaccharides.[PMID:25839135]
publication : 12401210|25839135|31540393|31140679|3028540|3674263|31339142|30026902|10721708|30671362|26176557|25039255|24044869|32567311|27857717|21491978|24910250|29077212|8014006|27107335|32679486|1747956|8679447|28352526|11341836|10837462|7960243|16158941|3297853|2431136|21734356|8625206|30732055|12716912|20128040|2582447|14659673
definition : A linear amino pentasaccharide comprising D-glucose at the reducing end with a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-α-D-galactosyl-(1→4)-β-D-galactosyl moiety at the 4-position.[CHEBI:141842]
term_xref : GlycoMotif:GGM.000076|GTC:G99053DY|CID:53239691|KEGG:G00097|CHEBI:62311|SugarBind_Ligand:12
synonyms : Globopentaosylceramide
function :
disease_associations : Pyelonephritis[SugarBind_Ligand:12]|Actinomycosis[SugarBind_Ligand:12|Influenza[SugarBind_Ligand:12]
wikipedia :
essentials_of_glycobiology : Chapter 11
GD1
term (main_entry) : GD1
glycan_dictionary_accession : GSD000082
glytoucan_accession : G81983KG
term_in_sentence : Hormonal and metabolic disturbances observed in both adult and paediatric patients with Gaucher disease type 1 (GD1) are discussed in this review. The PubMed database was used to identify articles on endocrine and metabolic disorders in GD1.[PMID:31791361]
publication : 5652802|25345088|31791361|29361370|31234327|30264864|25250137|7528216|31669751|20684311|16306603|10420586|7766692|31614613|26384672|31613991|19210136|8926633|29696051|32300455|7513313|26674302|20336376|24259734|31704237|21067946|30516933|27979707|26345314|30516941|31849452|27789132|30218706|29388611|20177787
definition :
term_xref : GlycoMotif:GGM.000105|GTC:G81983KG|CID:91859783|KEGG:G00126
synonyms : GD1c
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
GD1a
term (main_entry) : GD1a
glycan_dictionary_accession : GSD000083
glytoucan_accession : G46677TE | G45714BQ
term_in_sentence : Exclusive exposure of rat oligodendrocytes to GD1a, but not other gangliosides, overcomes aggregated fibronectin-induced inhibition of myelin membrane formation, in vitro, and OPC differentiation in fibronectin aggregate containing cuprizone-induced demyelinated lesions in male mice. [PMID: 28899916]
publication : 28899916|26860251|21930390|32906699|26054879|29951721|11745410|17653976|26119566|21554929|18435913|15342262|26865725|21151139|15716397|21492147|16942752|26973195|24449473|14999485|22735313|20589721|10521808|22929125|7827024|16897174|25062498|17227759
definition : A branched amino hexasaccharide consisting of the linear sequence α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to a galactose via an α-(2→3) linkage. The oligosaccharide of ganglioside GD1a.[CHEBI:59209]
term_xref : GlycoMotif:GGM.000106|GlycoMotif:GGM.000107|GTC:G46677TE|GTC:G45714BQ|CID:45266861|CHEBI:59209|GlycoEpitope:EP0056|SugarBind_Ligand:22|KEGG:G00111
synonyms : GD1alpha
function :
disease_associations : Gastroenteritis[SugarBind_Ligand:22]|Actinomycosis[SugarBind_Ligand:22]|Lazy leukocyte syndrome[SugarBind_Ligand:22]|Toxoplasmosis[SugarBind_Ligand:22]|Lyme disease[SugarBind_Ligand:22]|Botulism[SugarBind_Ligand:22]|Keratoconjunctivitis[SugarBind_Ligand:22]|Influenza[SugarBind_Ligand:22]
wikipedia :
essentials_of_glycobiology :
GD1b
term (main_entry) : GD1b
glycan_dictionary_accession : GSD000084
glytoucan_accession : G37184KW
term_in_sentence : Gangliosides have been known to play a role in the regulation of apoptosis in cancer cells. This study has employed disialyl-ganglioside GD1b to apoptosis in human breast cancer MCF-7 cells using exogenous treatment of the cells with GD1b and endogenous expression of GD1b in MCF-7 cells.[PMID: 27144558]
publication : 27144558|24859332|18625966|7945223|32518172|26710925|31837178|20594196|30985655|11511306|1742806|11123278|7685064|2709011|33279873|22929125|9179156|17964572|8821498|32726962|26560950|2611779|10072058|20030259|16415013|10797556|11342695|8619520|21519903|16199892|23777091|30246056|10481046
definition : A branched amino hexasaccharide comprising a β-D-galactosyl-(1→4)-β-D-glucose disaccharide, the galactosyl residue of which carries β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl and N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl disaccharide units through (2→4) and (2→3) linkages respectively. It is the carbohydrate portion of ganglioside GD1b.[CHEBI:59222]
term_xref : GlycoMotif:GGM.000108|GTC:G37184KW|CID:45266846|CHEBI:59222|GlycoEpitope:EP0059|SugarBind_Ligand:14
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 47
GD2
term (main_entry) : GD2
glycan_dictionary_accession : GSD000085
glytoucan_accession : G02657AK
term_in_sentence : Ganglioside GD2 is a tumor-associated surface antigen found in a broad spectrum of human cancers and stem cells. [PMID: 25440605]
publication : 28154831|32002293|32733795|28145567|31500597|31903906|29180536|28415563|25440605|30617136|25604432|30198960|31075227|31721713|30955398|32195035|27304202|31015228|31653037|31016728|30670592|30613134|29221154|30027525|29442009|31762628|30485077|25642322|29436609|29151270|24773917|30612272|27654028|26298772
definition : A branched amino pentasaccharide consisting of a linear sequence of two α-sialyl residues, a β-D-galactosyl residue and an N-acetyl-β-D-glucosamine residue linked respectively (2→8), (2→8) and (1→4), to the galactosyl residue of which is also linked (1→4) an N-acetyl-β-D-glucosaminyl residue. It is the carbohydrate portion of ganglioside GD2.[CHEBI:59218]
term_xref : GlycoMotif:GGM.000094|GTC:G02657AK|CID:45266844|CHEBI:59218|GlycoEpitope:EP0061|SugarBind_Ligand:88
synonyms :
function :
disease_associations : breast cancer[PMID:28415563]
wikipedia :
essentials_of_glycobiology : Chapter 11|Chatper 35
GD3
term (main_entry) : GD3
glycan_dictionary_accession : GSD000086
glytoucan_accession : G98544DH
term_in_sentence : In mammalian cells, the intracellular accumulation of ganglioside GD3, an acidic glycosphingolipid, contributes to mitochondrial damage, a crucial event during the apoptopic program. [PMID: 12531552]
publication : 30245960|27591028|12531552|29069780|12470841|29436609|28295752|27304202|31138648|27288875|30446565|8721669|3903474|16081368|32743804|24372645|26792897|20890432|25330147|20581115|11174200|16040804|23783008|17368571|11023989|12901230|21807667|7061953|2231782|19423750|22632091|18202973|6392333|15896784|8261439|20052288|12847141|12486096|12118012|19912988|22795094|18655184|17043769|21395555|2472199|19776077
definition : A linear amino tetrasaccharide consisting of two sialyl, one galactose and one glucose residue (at the reducing end) connected by sequential α-(2→8)-, α-(2→3)- and β-(1→4)-linkages. The oligosaccharide of ganglioside GD3.[CHEBI:59210]
term_xref : GlycoMotif:GGM.000091|GTC:G98544DH|CID:45266862|CHEBI:59210|GlycoEpitope:EP0062|SugarBind_Ligand:89|MeSH:C509062
synonyms :
function :
disease_associations : Cholera[SugarBind_Ligand:89]|Influenza[SugarBind_Ligand:89]
wikipedia :
essentials_of_glycobiology : Chapter 11
Globoside
term (main_entry) : Globoside
glycan_dictionary_accession : GSD000087
glytoucan_accession : G00061MO
term_in_sentence : Results of TLC immunostaining of neutral glycolipids from the cDNA-transfected cells also supported the identity of the newly synthesized component as globoside. [PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10993897 10993897 10993897] [https://pubmed.ncbi.nlm.nih.gov/10993897 10993897 10993897]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10993897 10993897 10993897] [https://pubmed.ncbi.nlm.nih.gov/10993897 10993897 10993897]]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10993897 10993897 10993897] [https://pubmed.ncbi.nlm.nih.gov/10993897 10993897 10993897]]
definition :
term_xref : GlycoMotif:GGM.000070|GTC:G00061MO
synonyms : Cytolipin K|Gb4|Globoside I|Globotetraosylceramide|P antigen
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 47
Globotetraosylceramide
term (main_entry) : Globotetraosylceramide
glycan_dictionary_accession : GSD000088
glytoucan_accession : G00061MO
term_in_sentence : Here we report that PUGNAc treatment provokes globotetraosylceramide (Gb4Cer) accumulation in human umbilical vein endothelial cells (HUVEC).[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28392398 28392398 28392398] [https://pubmed.ncbi.nlm.nih.gov/28392398 28392398 28392398]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28392398 28392398 28392398] [https://pubmed.ncbi.nlm.nih.gov/28392398 28392398 28392398]]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28392398 28392398 28392398] [https://pubmed.ncbi.nlm.nih.gov/28392398 28392398 28392398]]|25787850|23471986|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2559078 2559078 2559078] [https://pubmed.ncbi.nlm.nih.gov/2559078 2559078 2559078]]|32455599|2663859|32796033|3517161|20082214|30853699|15279935|[https://pubmed.ncbi.nlm.nih.gov/26104834 26104834 26104834]|20732996|30224239|31142708|30338271|25033755|[https://pubmed.ncbi.nlm.nih.gov/30413389 30413389 30413389]|7104376|29866658|24983355|6794884|31361021|21740983|33168837|31752441|28123520|29068380|24841197|27932383|28535204|31691795|27916888|27558838|10227680|26464281|22348006|22279060|25156739|32314902|22718629|23701631|23906628|8613382|23555772|20059899|7868240
definition : An amino tetrasaccharide consisting of 2-acetamido-2-deoxy-β-D-galactopyranosyl, α-D-galactopyranosyl, β-D-galactopyranosyl, and β-D-glucopyranose units joined together in sequence by (1→3), (1→4), and (1→4) glycosidic linkages, respectively.[CHEBI:145578]
term_xref : GlycoMotif:GGM.000070|GlycoEpitope:EP0073|CID:5288889|CHEBI:145578|SugarBind_Ligand:18|MeSH:C024032
synonyms : Gb4Cer|Gb4|Globoside|P antigen|Cytolipin K
function :
disease_associations : Actinomycosis[SugarBind_Ligand:18]|Pyelonephritis[SugarBind_Ligand:18]|Acute cystitis[SugarBind_Ligand:18]|Shigellosis[SugarBind_Ligand:18]|Lazy leukocyte syndrome[SugarBind_Ligand:18]|Influenza[SugarBind_Ligand:18]
wikipedia :
essentials_of_glycobiology : Chapter 11
Globotriaosylceramide
term (main_entry) : Globotriaosylceramide
glycan_dictionary_accession : GSD000089
glytoucan_accession : G00059MO
term_in_sentence : Defects in the gene encoding α-galactosidase A lead to accumulation of globotriaosylceramide (GL3) in various cell types.[PMID:[https://pubmed.ncbi.nlm.nih.gov/32127409 32127409 32127409]]
publication : [https://pubmed.ncbi.nlm.nih.gov/32127409 32127409 32127409]|28674962|30875019|[https://pubmed.ncbi.nlm.nih.gov/30413389 30413389 30413389]|31778662|31101366|24335674|31241709|24158513|28947349|31566927|28672034|31939530|29530250|27851774|26426881|25031264|29982630|24496231|29983334|28756410|27190352|29274327|[https://pubmed.ncbi.nlm.nih.gov/29099167 29099167 29099167]|28402705|23680766|28625968|26960552|26797827|22742555|27756537|31630715|3827883|28384397|29523338|31010832|27195818|26661087|23093409|30879639|27081853|17409683|29921669|25575293|26291612|23146289|25857295|26070511
definition : Globotriaosylceramide is a type of globoside(glycosphingolipid) which is formed by alpha linkage of galactose to lactosylceramide. The reaction is catalyzed by enzyme A4GALT.[Wiki:Globotriaosylceramide]
term_xref : GlycoMotif:GGM.000068|GTC:G00059MO|GlycoEpitope:EP0071|CID:5279515|CHEBI:68485|MeSH:C018549|SugarBind_Ligand:27
synonyms : Gb3|GL3|Pk antigen|P^K antigen|Gb(3)|Gb_3|CD77|globotriaosylceramide|ceramide trihexoside|CTH|Trihexosylceramide
function :
disease_associations : Pyelonephritis[SugarBind_Ligand:27]|Acute cystitis[SugarBind_Ligand:27]|Shigellosis[SugarBind_Ligand:27]|Lyme disease[SugarBind_Ligand:27]|Cutaneous lesions[SugarBind_Ligand:27]|Diarrhea[SugarBind_Ligand:27]
wikipedia :
essentials_of_glycobiology :
Glucosylceramide
term (main_entry) : Glucosylceramide
glycan_dictionary_accession : GSD000090
glytoucan_accession : G71142DF
term_in_sentence : Glucosylceramide (GlcCer), the initial GSL synthesized from ceramide by GCS (GlcCer synthase), is required for embryonic survival, but its role in the lung is unknown.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31265321 31265321 31265321] [https://pubmed.ncbi.nlm.nih.gov/31265321 31265321 31265321]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31265321 31265321 31265321] [https://pubmed.ncbi.nlm.nih.gov/31265321 31265321 31265321]]|29290548|29627573|20919653|28427052|30550553|24415933|31914593|31051284|23073611|30146946|31619618|26840726|29750412|8065509|27412675|27840079|[https://pubmed.ncbi.nlm.nih.gov/30611744 30611744 30611744]|31353719|25661072|28686011|25803043|28865794|28154347|31466334|30242129|12531551|30639288|30864417|[https://pubmed.ncbi.nlm.nih.gov/27711049 27711049 27711049]|22764777|27905603|29077010|28744000|23555901|24115322|12803919|29204666|23628459|28851512|26136173|23563543|30110701|26572681|2193825|29926415|31727994|27479571
definition : Cerebrosides which contain as their polar head group a glucose moiety bound in glycosidic linkage to the hydroxyl group of ceramides. Their accumulation in tissue, due to a defect in beta-glucosidase, is the cause of Gaucher's disease.[MeSH:D005963]
term_xref : MeSH:D005963|GlycoMotif:GGM.000060|CHEBI:83264|GTC:G71142DF
synonyms : GlcCer|Glucocerebroside|Ceramide monohexoside|CMH
function : The structural characterization of mixed membranes made of cationic lipids and glucosylceramides may be important for developing novel immunotherapeutic tools such as vaccine adjuvants.[PMID:[https://pubmed.ncbi.nlm.nih.gov/30611744 30611744 30611744]]|Glucosylceramide (GlcCer), the initial GSL synthesized from ceramide by GCS (GlcCer synthase), is required for embryonic survival, but its role in the lung is unknown.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31265321 31265321 31265321] [https://pubmed.ncbi.nlm.nih.gov/31265321 31265321 31265321]]]
disease_associations : Gaucher's Disease|Pharyngitis[SugarBind_Ligand:3]|Tracheobronchitis[SugarBind_Ligand:3]|Pleuropneumonia[SugarBind_Ligand:3]|Porcine fibrinohemorrhagic necrotizing pleuropneumonia[SugarBind_Ligand:3]|Diarrhea[SugarBind_Ligand:3]
wikipedia :
essentials_of_glycobiology : Chapter 31
GM1
term (main_entry) : GM1
glycan_dictionary_accession : GSD000091
glytoucan_accession : G48558GR
term_in_sentence : GM1-induced fluidization of the phospholipid membranes and probable physical contact between bulky sugar head group of GM1 and spectrin, may explain the modulatory role of GM1 on aminophospholipid interactions with nonerythroid brain spectrin.[PMID: [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29920238 29920238 29920238] [https://pubmed.ncbi.nlm.nih.gov/29920238 29920238 29920238]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18524657 18524657 18524657] [https://pubmed.ncbi.nlm.nih.gov/18524657 18524657 18524657]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31761138 31761138 31761138] [https://pubmed.ncbi.nlm.nih.gov/31761138 31761138 31761138]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/36180805 36180805 36180805] [https://pubmed.ncbi.nlm.nih.gov/36180805 36180805 36180805]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29920238 29920238 29920238] [https://pubmed.ncbi.nlm.nih.gov/29920238 29920238 29920238]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29920238 29920238 29920238] [https://pubmed.ncbi.nlm.nih.gov/29920238 29920238 29920238]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490] [https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490] [https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490] [https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490] [https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31937438 31937438 31937438] [https://pubmed.ncbi.nlm.nih.gov/31937438 31937438 31937438]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25762012 25762012 25762012] [https://pubmed.ncbi.nlm.nih.gov/25762012 25762012 25762012]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25931034 25931034 25931034] [https://pubmed.ncbi.nlm.nih.gov/25931034 25931034 25931034]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31776384 31776384 31776384] [https://pubmed.ncbi.nlm.nih.gov/31776384 31776384 31776384]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32013258 32013258 32013258] [https://pubmed.ncbi.nlm.nih.gov/32013258 32013258 32013258]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30776097 30776097 30776097] [https://pubmed.ncbi.nlm.nih.gov/30776097 30776097 30776097]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31048748 31048748 31048748] [https://pubmed.ncbi.nlm.nih.gov/31048748 31048748 31048748]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31447771 31447771 31447771] [https://pubmed.ncbi.nlm.nih.gov/31447771 31447771 31447771]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30292198 30292198 30292198] [https://pubmed.ncbi.nlm.nih.gov/30292198 30292198 30292198]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28796418 28796418 28796418] [https://pubmed.ncbi.nlm.nih.gov/28796418 28796418 28796418]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27806275 27806275 27806275] [https://pubmed.ncbi.nlm.nih.gov/27806275 27806275 27806275]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21076871 21076871 21076871] [https://pubmed.ncbi.nlm.nih.gov/21076871 21076871 21076871]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27552916 27552916 27552916] [https://pubmed.ncbi.nlm.nih.gov/27552916 27552916 27552916]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17986147 17986147 17986147] [https://pubmed.ncbi.nlm.nih.gov/17986147 17986147 17986147]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26960162 26960162 26960162] [https://pubmed.ncbi.nlm.nih.gov/26960162 26960162 26960162]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27815022 27815022 27815022] [https://pubmed.ncbi.nlm.nih.gov/27815022 27815022 27815022]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25851126 25851126 25851126] [https://pubmed.ncbi.nlm.nih.gov/25851126 25851126 25851126]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32916822 32916822 32916822] [https://pubmed.ncbi.nlm.nih.gov/32916822 32916822 32916822]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11462671 11462671 11462671] [https://pubmed.ncbi.nlm.nih.gov/11462671 11462671 11462671]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28236574 28236574 28236574] [https://pubmed.ncbi.nlm.nih.gov/28236574 28236574 28236574]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15911874 15911874 15911874] [https://pubmed.ncbi.nlm.nih.gov/15911874 15911874 15911874]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28577204 28577204 28577204] [https://pubmed.ncbi.nlm.nih.gov/28577204 28577204 28577204]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28497346 28497346 28497346] [https://pubmed.ncbi.nlm.nih.gov/28497346 28497346 28497346]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1794005 1794005 1794005] [https://pubmed.ncbi.nlm.nih.gov/1794005 1794005 1794005]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31934908 31934908 31934908] [https://pubmed.ncbi.nlm.nih.gov/31934908 31934908 31934908]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30267299 30267299 30267299] [https://pubmed.ncbi.nlm.nih.gov/30267299 30267299 30267299]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/16902585 16902585 16902585] [https://pubmed.ncbi.nlm.nih.gov/16902585 16902585 16902585]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29439846 29439846 29439846] [https://pubmed.ncbi.nlm.nih.gov/29439846 29439846 29439846]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32325905 32325905 32325905] [https://pubmed.ncbi.nlm.nih.gov/32325905 32325905 32325905]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29747823 29747823 29747823] [https://pubmed.ncbi.nlm.nih.gov/29747823 29747823 29747823]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27576485 27576485 27576485] [https://pubmed.ncbi.nlm.nih.gov/27576485 27576485 27576485]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26338710 26338710 26338710] [https://pubmed.ncbi.nlm.nih.gov/26338710 26338710 26338710]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27858734 27858734 27858734] [https://pubmed.ncbi.nlm.nih.gov/27858734 27858734 27858734]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24501414 24501414 24501414] [https://pubmed.ncbi.nlm.nih.gov/24501414 24501414 24501414]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26818965 26818965 26818965] [https://pubmed.ncbi.nlm.nih.gov/26818965 26818965 26818965]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26629687 26629687 26629687] [https://pubmed.ncbi.nlm.nih.gov/26629687 26629687 26629687]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26958633 26958633 26958633] [https://pubmed.ncbi.nlm.nih.gov/26958633 26958633 26958633]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1854596 1854596 1854596] [https://pubmed.ncbi.nlm.nih.gov/1854596 1854596 1854596]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32134593 32134593 32134593] [https://pubmed.ncbi.nlm.nih.gov/32134593 32134593 32134593]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32198666 32198666 32198666] [https://pubmed.ncbi.nlm.nih.gov/32198666 32198666 32198666]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6619101 6619101 6619101] [https://pubmed.ncbi.nlm.nih.gov/6619101 6619101 6619101]]
definition : A branched amino pentasaccharide consisting of the linear sequence β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to the inner galactose via an α-(2→3) linkage. The oligosaccharide of ganglioside GM1a.[CHEBI:59208]
term_xref : GlycoMotif:GGM.000098|GTC:G48558GR|CID:196569|CHEBI:59208|GlycoEpitope:EP0050|SugarBind_Ligand:13|KEGG:G00110
synonyms : GM1 ganglioside|GM1-ganglioside
function : The branched pentasaccharide chain of ganglioside GM1 is a prominent cell surface ligand, for example, for cholera toxin or tumor growth-regulatory homodimeric galectins.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/16267866 16267866 16267866]/ [https://pubmed.ncbi.nlm.nih.gov/16267866 16267866 16267866]]]
disease_associations : GM1 gangliosidosis (GM1) [PMID: [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490] [https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490] [https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490]]]/ [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490] [https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490] [https://pubmed.ncbi.nlm.nih.gov/33859490 33859490 33859490]]]]]|Gastroenteritis[SugarBind_Ligand:13]|Actinomycosis[SugarBind_Ligand:13]|Lazy leukocyte syndrome[SugarBind_Ligand:13]|Toxoplasmosis[SugarBind_Ligand:13]|Cholera[SugarBind_Ligand:13]|Botulism[SugarBind_Ligand:13]
wikipedia : https://en.wikipedia.org/wiki/GM1
essentials_of_glycobiology : Chapter 11| Chapter 14
GM2
term (main_entry) : GM2
glycan_dictionary_accession : GSD000092
glytoucan_accession : G79389NT
term_in_sentence : GM1 gangliosidosis has both central nervous system and systemic findings; while, GM2 gangliosidosis is restricted primarily to the central nervous system.[PMID: [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27491214 27491214 27491214] [https://pubmed.ncbi.nlm.nih.gov/27491214 27491214 27491214]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29618308 29618308 29618308] [https://pubmed.ncbi.nlm.nih.gov/29618308 29618308 29618308]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27491214 27491214 27491214] [https://pubmed.ncbi.nlm.nih.gov/27491214 27491214 27491214]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27491214 27491214 27491214] [https://pubmed.ncbi.nlm.nih.gov/27491214 27491214 27491214]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32867370 32867370 32867370] [https://pubmed.ncbi.nlm.nih.gov/32867370 32867370 32867370]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30030044 30030044 30030044] [https://pubmed.ncbi.nlm.nih.gov/30030044 30030044 30030044]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27499644 27499644 27499644] [https://pubmed.ncbi.nlm.nih.gov/27499644 27499644 27499644]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31097363 31097363 31097363] [https://pubmed.ncbi.nlm.nih.gov/31097363 31097363 31097363]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29100724 29100724 29100724] [https://pubmed.ncbi.nlm.nih.gov/29100724 29100724 29100724]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27402091 27402091 27402091] [https://pubmed.ncbi.nlm.nih.gov/27402091 27402091 27402091]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31852956 31852956 31852956] [https://pubmed.ncbi.nlm.nih.gov/31852956 31852956 31852956]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30389374 30389374 30389374] [https://pubmed.ncbi.nlm.nih.gov/30389374 30389374 30389374]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30988135 30988135 30988135] [https://pubmed.ncbi.nlm.nih.gov/30988135 30988135 30988135]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8786814 8786814 8786814] [https://pubmed.ncbi.nlm.nih.gov/8786814 8786814 8786814]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/14533808 14533808 14533808] [https://pubmed.ncbi.nlm.nih.gov/14533808 14533808 14533808]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23370522 23370522 23370522] [https://pubmed.ncbi.nlm.nih.gov/23370522 23370522 23370522]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28192816 28192816 28192816] [https://pubmed.ncbi.nlm.nih.gov/28192816 28192816 28192816]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32692591 32692591 32692591] [https://pubmed.ncbi.nlm.nih.gov/32692591 32692591 32692591]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29106755 29106755 29106755] [https://pubmed.ncbi.nlm.nih.gov/29106755 29106755 29106755]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28833537 28833537 28833537] [https://pubmed.ncbi.nlm.nih.gov/28833537 28833537 28833537]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11339652 11339652 11339652] [https://pubmed.ncbi.nlm.nih.gov/11339652 11339652 11339652]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9728335 9728335 9728335] [https://pubmed.ncbi.nlm.nih.gov/9728335 9728335 9728335]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27270764 27270764 27270764] [https://pubmed.ncbi.nlm.nih.gov/27270764 27270764 27270764]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9714704 9714704 9714704] [https://pubmed.ncbi.nlm.nih.gov/9714704 9714704 9714704]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26175473 26175473 26175473] [https://pubmed.ncbi.nlm.nih.gov/26175473 26175473 26175473]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27018595 27018595 27018595] [https://pubmed.ncbi.nlm.nih.gov/27018595 27018595 27018595]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28615102 28615102 28615102] [https://pubmed.ncbi.nlm.nih.gov/28615102 28615102 28615102]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28974375 28974375 28974375] [https://pubmed.ncbi.nlm.nih.gov/28974375 28974375 28974375]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32951593 32951593 32951593] [https://pubmed.ncbi.nlm.nih.gov/32951593 32951593 32951593]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11462672 11462672 11462672] [https://pubmed.ncbi.nlm.nih.gov/11462672 11462672 11462672]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28955902 28955902 28955902] [https://pubmed.ncbi.nlm.nih.gov/28955902 28955902 28955902]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17192692 17192692 17192692] [https://pubmed.ncbi.nlm.nih.gov/17192692 17192692 17192692]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26538065 26538065 26538065] [https://pubmed.ncbi.nlm.nih.gov/26538065 26538065 26538065]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25421609 25421609 25421609] [https://pubmed.ncbi.nlm.nih.gov/25421609 25421609 25421609]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9572057 9572057 9572057] [https://pubmed.ncbi.nlm.nih.gov/9572057 9572057 9572057]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11596983 11596983 11596983] [https://pubmed.ncbi.nlm.nih.gov/11596983 11596983 11596983]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15264019 15264019 15264019] [https://pubmed.ncbi.nlm.nih.gov/15264019 15264019 15264019]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23236285 23236285 23236285] [https://pubmed.ncbi.nlm.nih.gov/23236285 23236285 23236285]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11596984 11596984 11596984] [https://pubmed.ncbi.nlm.nih.gov/11596984 11596984 11596984]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31261761 31261761 31261761] [https://pubmed.ncbi.nlm.nih.gov/31261761 31261761 31261761]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30113798 30113798 30113798] [https://pubmed.ncbi.nlm.nih.gov/30113798 30113798 30113798]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24391178 24391178 24391178] [https://pubmed.ncbi.nlm.nih.gov/24391178 24391178 24391178]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24309906 24309906 24309906] [https://pubmed.ncbi.nlm.nih.gov/24309906 24309906 24309906]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22224667 22224667 22224667] [https://pubmed.ncbi.nlm.nih.gov/22224667 22224667 22224667]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7980537 7980537 7980537] [https://pubmed.ncbi.nlm.nih.gov/7980537 7980537 7980537]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18272501 18272501 18272501] [https://pubmed.ncbi.nlm.nih.gov/18272501 18272501 18272501]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9006924 9006924 9006924] [https://pubmed.ncbi.nlm.nih.gov/9006924 9006924 9006924]]|
definition : A branched amino tetrasaccharide consisting of the linear sequence β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to the galactose via an α-(2→3) linkage. Corresponds to the carbohydrate portion of ganglioside GM2.[CHEBI:59220]
term_xref : GlycoMotif:GGM.000095|GTC:G79389NT|CID:[https://pubmed.ncbi.nlm.nih.gov/45266845 45266845 45266845]|CHEBI:59220|GlycoEpitope:EP0051|SugarBind_Ligand:39|KEGG:G00109|KEGG:G10351
synonyms :
function :
disease_associations : lung adenocarcinoma[GlycoEpitope:EP0051]|embryonal carcinoma[GlycoEpitope:EP0051]|germ cell tumor[GlycoEpitope:EP0051]|teratocarcinoma[GlycoEpitope:EP0051]|squamous cell carcinoma[GlycoEpitope:EP0051]|Gastroenteritis[SugarBind_Ligand:39]|Cholera[SugarBind_Ligand:39]|Clostridial myonecrosis[SugarBind_Ligand:39]|Tetanus[SugarBind_Ligand:39]
wikipedia : https://en.wikipedia.org/wiki/GM1_gangliosidoses
essentials_of_glycobiology : Chapter 11
GM3
term (main_entry) : GM3
glycan_dictionary_accession : GSD000093
glytoucan_accession : G91237TK
term_in_sentence : We also demonstrated an essential role of GM3 in murine and human auditory systems; a common pathological feature of GM3S deficiency is deafness. [PMID: [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29747813 29747813 29747813] [https://pubmed.ncbi.nlm.nih.gov/29747813 29747813 29747813]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29376491 29376491 29376491] [https://pubmed.ncbi.nlm.nih.gov/29376491 29376491 29376491]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29747813 29747813 29747813] [https://pubmed.ncbi.nlm.nih.gov/29747813 29747813 29747813]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29747813 29747813 29747813] [https://pubmed.ncbi.nlm.nih.gov/29747813 29747813 29747813]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25613425 25613425 25613425] [https://pubmed.ncbi.nlm.nih.gov/25613425 25613425 25613425]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30318083 30318083 30318083] [https://pubmed.ncbi.nlm.nih.gov/30318083 30318083 30318083]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31526872 31526872 31526872] [https://pubmed.ncbi.nlm.nih.gov/31526872 31526872 31526872]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31004109 31004109 31004109] [https://pubmed.ncbi.nlm.nih.gov/31004109 31004109 31004109]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28019668 28019668 28019668] [https://pubmed.ncbi.nlm.nih.gov/28019668 28019668 28019668]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26434718 26434718 26434718] [https://pubmed.ncbi.nlm.nih.gov/26434718 26434718 26434718]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27313500 27313500 27313500] [https://pubmed.ncbi.nlm.nih.gov/27313500 27313500 27313500]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27539856 27539856 27539856] [https://pubmed.ncbi.nlm.nih.gov/27539856 27539856 27539856]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30111401 30111401 30111401] [https://pubmed.ncbi.nlm.nih.gov/30111401 30111401 30111401]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28544772 28544772 28544772] [https://pubmed.ncbi.nlm.nih.gov/28544772 28544772 28544772]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29407985 29407985 29407985] [https://pubmed.ncbi.nlm.nih.gov/29407985 29407985 29407985]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19364317 19364317 19364317] [https://pubmed.ncbi.nlm.nih.gov/19364317 19364317 19364317]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30190430 30190430 30190430] [https://pubmed.ncbi.nlm.nih.gov/30190430 30190430 30190430]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31297734 31297734 31297734] [https://pubmed.ncbi.nlm.nih.gov/31297734 31297734 31297734]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30091781 30091781 30091781] [https://pubmed.ncbi.nlm.nih.gov/30091781 30091781 30091781]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26043887 26043887 26043887] [https://pubmed.ncbi.nlm.nih.gov/26043887 26043887 26043887]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32183071 32183071 32183071] [https://pubmed.ncbi.nlm.nih.gov/32183071 32183071 32183071]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30665141 30665141 30665141] [https://pubmed.ncbi.nlm.nih.gov/30665141 30665141 30665141]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27873002 27873002 27873002] [https://pubmed.ncbi.nlm.nih.gov/27873002 27873002 27873002]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25801320 25801320 25801320] [https://pubmed.ncbi.nlm.nih.gov/25801320 25801320 25801320]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30209782 30209782 30209782] [https://pubmed.ncbi.nlm.nih.gov/30209782 30209782 30209782]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32378734 32378734 32378734] [https://pubmed.ncbi.nlm.nih.gov/32378734 32378734 32378734]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23050851 23050851 23050851] [https://pubmed.ncbi.nlm.nih.gov/23050851 23050851 23050851]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22768242 22768242 22768242] [https://pubmed.ncbi.nlm.nih.gov/22768242 22768242 22768242]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/14993837 14993837 14993837] [https://pubmed.ncbi.nlm.nih.gov/14993837 14993837 14993837]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24934090 24934090 24934090] [https://pubmed.ncbi.nlm.nih.gov/24934090 24934090 24934090]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17638075 17638075 17638075] [https://pubmed.ncbi.nlm.nih.gov/17638075 17638075 17638075]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21518140 21518140 21518140] [https://pubmed.ncbi.nlm.nih.gov/21518140 21518140 21518140]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26102277 26102277 26102277] [https://pubmed.ncbi.nlm.nih.gov/26102277 26102277 26102277]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19759399 19759399 19759399] [https://pubmed.ncbi.nlm.nih.gov/19759399 19759399 19759399]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24502144 24502144 24502144] [https://pubmed.ncbi.nlm.nih.gov/24502144 24502144 24502144]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25303960 25303960 25303960] [https://pubmed.ncbi.nlm.nih.gov/25303960 25303960 25303960]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23564406 23564406 23564406] [https://pubmed.ncbi.nlm.nih.gov/23564406 23564406 23564406]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/16636105 16636105 16636105] [https://pubmed.ncbi.nlm.nih.gov/16636105 16636105 16636105]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/16491123 16491123 16491123] [https://pubmed.ncbi.nlm.nih.gov/16491123 16491123 16491123]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11259118 11259118 11259118] [https://pubmed.ncbi.nlm.nih.gov/11259118 11259118 11259118]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15102521 15102521 15102521] [https://pubmed.ncbi.nlm.nih.gov/15102521 15102521 15102521]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12724312 12724312 12724312] [https://pubmed.ncbi.nlm.nih.gov/12724312 12724312 12724312]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24985965 24985965 24985965] [https://pubmed.ncbi.nlm.nih.gov/24985965 24985965 24985965]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8496625 8496625 8496625] [https://pubmed.ncbi.nlm.nih.gov/8496625 8496625 8496625]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25403557 25403557 25403557] [https://pubmed.ncbi.nlm.nih.gov/25403557 25403557 25403557]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15690123 15690123 15690123] [https://pubmed.ncbi.nlm.nih.gov/15690123 15690123 15690123]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15939439 15939439 15939439] [https://pubmed.ncbi.nlm.nih.gov/15939439 15939439 15939439]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25893133 25893133 25893133] [https://pubmed.ncbi.nlm.nih.gov/25893133 25893133 25893133]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23591593 23591593 23591593] [https://pubmed.ncbi.nlm.nih.gov/23591593 23591593 23591593]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20634908 20634908 20634908] [https://pubmed.ncbi.nlm.nih.gov/20634908 20634908 20634908]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2004380 2004380 2004380] [https://pubmed.ncbi.nlm.nih.gov/2004380 2004380 2004380]]|739008|
definition : Ganglioside GM3 (d18:1/16:0) is a glycosphingolipid (ceramide and oligosaccharide)or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It is a component the cell plasma membrane which modulates cell signal transduction events. Gangliosides have been found to be highly important in immunology. Ganglioside GM3 carries a net-negative charge at pH 7.0 and is acidic. Gangliosides can amount to 6% of the weight of lipids from brain, but they are found at low levels in all animal tissuesGangliosides are glycosphingolipids. There are four types of glycosphingolipids, the cerebrosides, sulfatides, globosides and gangliosides. Gangliosides are very similar to globosides except that they also contain N-acetyl neuraminic acid (NANA) in varying amounts. The specific names for the gangliosides provide information about their structure. The letter G refers to ganglioside, and the subscripts M, D, T and Q indicate that the molecule contains mono-, di-, tri and quatra-sialic acid. The numbered subscripts 1, 2 and 3 refer to the carbohydrate sequence that is attached to the ceramide. In particular, 1 stands for GalGalNAcGalGlc-ceramide, 2 stands for GalNAcGalGlc-ceramide and 3 stands for GalGlc-ceramide. Deficiencies in lysosomal enzymes that degrade the carbohydrate portions of various gangliosides are responsible for a number of lysosomal storage diseases such as Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis. The carbohydrate portion of the ganglioside GM1 is the site of attachment of cholera toxin, the protein secreted by Vibrio cholerae.[HMDB[https://pubmed.ncbi.nlm.nih.gov/0004844 0004844 0004844]]
term_xref : GlycoMotif:GGM.000090|GTC:G91237TK|CID:5288424|CHEBI:59226|GlycoEpitope:EP0053|SugarBind_Ligand:35
synonyms :
function : Membrane stabilizer|Energy source|Energy storage|Molecular messenger:|Signaling molecule[HMDB[https://pubmed.ncbi.nlm.nih.gov/0004844 0004844 0004844]]
disease_associations : Gastroenteritis[SugarBind_Ligand:35]|Chronic gastritis[SugarBind_Ligand:35]|Toxoplasmosis[SugarBind_Ligand:35]|Peptic ulcerSugarBind_Ligand:35]|Gastric cancer[SugarBind_Ligand:35]|Influenza[SugarBind_Ligand:35]|Diarrhea[SugarBind_Ligand:35]|Botulism[SugarBind_Ligand:35]
wikipedia :
essentials_of_glycobiology : Chapter 37
GM4
term (main_entry) : GM4
glycan_dictionary_accession : GSD000094
glytoucan_accession : G30207PZ
term_in_sentence : GM4 is synthesized by the sialylation of galactosylceramide (GalCer), while the ganglioside GM3 is synthesized by the sialylation of lactosylceramide (LacCer).[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23999868 23999868 23999868] [https://pubmed.ncbi.nlm.nih.gov/23999868 23999868 23999868]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23999868 23999868 23999868] [https://pubmed.ncbi.nlm.nih.gov/23999868 23999868 23999868]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23999868 23999868 23999868] [https://pubmed.ncbi.nlm.nih.gov/23999868 23999868 23999868]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23999868 23999868 23999868] [https://pubmed.ncbi.nlm.nih.gov/23999868 23999868 23999868]]]]]
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23203271]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7057115 7057115 7057115] [https://pubmed.ncbi.nlm.nih.gov/7057115 7057115 7057115]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26362868 26362868 26362868] [https://pubmed.ncbi.nlm.nih.gov/26362868 26362868 26362868]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6170387 6170387 6170387] [https://pubmed.ncbi.nlm.nih.gov/6170387 6170387 6170387]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18034482 18034482 18034482] [https://pubmed.ncbi.nlm.nih.gov/18034482 18034482 18034482]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7076644 7076644 7076644] [https://pubmed.ncbi.nlm.nih.gov/7076644 7076644 7076644]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2391348 2391348 2391348] [https://pubmed.ncbi.nlm.nih.gov/2391348 2391348 2391348]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25464080 25464080 25464080] [https://pubmed.ncbi.nlm.nih.gov/25464080 25464080 25464080]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3701369 3701369 3701369] [https://pubmed.ncbi.nlm.nih.gov/3701369 3701369 3701369]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11217952 11217952 11217952] [https://pubmed.ncbi.nlm.nih.gov/11217952 11217952 11217952]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6201236 6201236 6201236] [https://pubmed.ncbi.nlm.nih.gov/6201236 6201236 6201236]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30744426 30744426 30744426] [https://pubmed.ncbi.nlm.nih.gov/30744426 30744426 30744426]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9388026 9388026 9388026] [https://pubmed.ncbi.nlm.nih.gov/9388026 9388026 9388026]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27177620 27177620 27177620] [https://pubmed.ncbi.nlm.nih.gov/27177620 27177620 27177620]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30246056 30246056 30246056] [https://pubmed.ncbi.nlm.nih.gov/30246056 30246056 30246056]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15979459 15979459 15979459] [https://pubmed.ncbi.nlm.nih.gov/15979459 15979459 15979459]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7586078 7586078 7586078] [https://pubmed.ncbi.nlm.nih.gov/7586078 7586078 7586078]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6779816 6779816 6779816] [https://pubmed.ncbi.nlm.nih.gov/6779816 6779816 6779816]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29402905 29402905 29402905] [https://pubmed.ncbi.nlm.nih.gov/29402905 29402905 29402905]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7335153 7335153 7335153] [https://pubmed.ncbi.nlm.nih.gov/7335153 7335153 7335153]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3306476 3306476 3306476] [https://pubmed.ncbi.nlm.nih.gov/3306476 3306476 3306476]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17499534 17499534 17499534] [https://pubmed.ncbi.nlm.nih.gov/17499534 17499534 17499534]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7074082 7074082 7074082] [https://pubmed.ncbi.nlm.nih.gov/7074082 7074082 7074082]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9668345 9668345 9668345] [https://pubmed.ncbi.nlm.nih.gov/9668345 9668345 9668345]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3701884 3701884 3701884] [https://pubmed.ncbi.nlm.nih.gov/3701884 3701884 3701884]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26862430 26862430 26862430] [https://pubmed.ncbi.nlm.nih.gov/26862430 26862430 26862430]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6831238 6831238 6831238] [https://pubmed.ncbi.nlm.nih.gov/6831238 6831238 6831238]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27311552 27311552 27311552] [https://pubmed.ncbi.nlm.nih.gov/27311552 27311552 27311552]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26831445 26831445 26831445] [https://pubmed.ncbi.nlm.nih.gov/26831445 26831445 26831445]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24417799 24417799 24417799] [https://pubmed.ncbi.nlm.nih.gov/24417799 24417799 24417799]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7097284 7097284 7097284] [https://pubmed.ncbi.nlm.nih.gov/7097284 7097284 7097284]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/4169231 4169231 4169231] [https://pubmed.ncbi.nlm.nih.gov/4169231 4169231 4169231]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/16854400 16854400 16854400] [https://pubmed.ncbi.nlm.nih.gov/16854400 16854400 16854400]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26483798 26483798 26483798] [https://pubmed.ncbi.nlm.nih.gov/26483798 26483798 26483798]]
definition : An amino disaccharide consisting of β-D-galactose having an α-N-acetylneuraminyl residue attached at the 3-position [CHEBI:63155]
term_xref : GlycoMotif:GGM.000089|GTC:G30207PZ|CID:5289366|CHEBI:63155|KEGG:G00317|SugarBind_Ligand:110
synonyms : Sialylated GalCer
function :
disease_associations : Chronic gastritis[SugarBind_Ligand:110]|Peptic ulcers[SugarBind_Ligand:110]|Gastric cancer[SugarBind_Ligand:110]
wikipedia :
essentials_of_glycobiology : Chapter 11|Chapter 15|Chapter 44|Appendix 45A
GP1c
term (main_entry) : GP1c
glycan_dictionary_accession : GSD000095
glytoucan_accession : G93805MV
term_in_sentence : n this report, we describe an efficient convergent synthesis of the GP1c glycolipid epitope, which is one of the most complex c-series gangliosides. [PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458] [https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458] [https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458] [https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458] [https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458]]]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458] [https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458] [https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19053458 19053458 19053458] 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10775425 10775425] [https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425] [https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425] [https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425] [https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]]] 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1879553]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494] [https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494] [https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494] [https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494] [https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8969459 8969459 8969459] [https://pubmed.ncbi.nlm.nih.gov/8969459 8969459 8969459]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578] [https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578] [https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578] [https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578] [https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12031286 12031286 12031286] [https://pubmed.ncbi.nlm.nih.gov/12031286 12031286 12031286]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12031286 12031286 12031286] [https://pubmed.ncbi.nlm.nih.gov/12031286 12031286 12031286]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1304332 1304332 1304332] [https://pubmed.ncbi.nlm.nih.gov/1304332 1304332 1304332]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9153001 9153001 9153001] [https://pubmed.ncbi.nlm.nih.gov/9153001 9153001 9153001]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9153001 9153001 9153001] [https://pubmed.ncbi.nlm.nih.gov/9153001 9153001 9153001]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776] [https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776] [https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776] [https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776] [https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776]]]]
definition :
term_xref : GlycoMotif:GGM.000118|GTC:G93805MV
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 11|Chapter 14|Chapter 27|Chapter 35|Chapter 45 |Chapter 47|Chapter 49
GQ1b
term (main_entry) : GQ1b
glycan_dictionary_accession : GSD000096
glytoucan_accession : G18625KA
term_in_sentence : Bilateral infusion of GQ1b into the hippocampus ameliorates cognitive deficits in the triple-transgenic AD mouse model (3xTg-AD).[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474] [https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474] [https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474] [https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474] [https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474]]]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30798387 30798387 30798387] [https://pubmed.ncbi.nlm.nih.gov/30798387 30798387 30798387]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474] [https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474] [https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474] [https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474] [https://pubmed.ncbi.nlm.nih.gov/31186474 31186474 31186474]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26704905 26704905 26704905] [https://pubmed.ncbi.nlm.nih.gov/26704905 26704905 26704905]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23677659 23677659 23677659] [https://pubmed.ncbi.nlm.nih.gov/23677659 23677659 23677659]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26984947 26984947 26984947] [https://pubmed.ncbi.nlm.nih.gov/26984947 26984947 26984947]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24184316 24184316 24184316] [https://pubmed.ncbi.nlm.nih.gov/24184316 24184316 24184316]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23804237 23804237 23804237] [https://pubmed.ncbi.nlm.nih.gov/23804237 23804237 23804237]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23804237 23804237 23804237] [https://pubmed.ncbi.nlm.nih.gov/23804237 23804237 23804237]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9819299 9819299 9819299] [https://pubmed.ncbi.nlm.nih.gov/9819299 9819299 9819299]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18514410 18514410 18514410] [https://pubmed.ncbi.nlm.nih.gov/18514410 18514410 18514410]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22189683 22189683 22189683] [https://pubmed.ncbi.nlm.nih.gov/22189683 22189683 22189683]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24859332 24859332 24859332] [https://pubmed.ncbi.nlm.nih.gov/24859332 24859332 24859332]]
definition : An amino oligosaccharide that is a branched octasaccharide derivative consisting of four sialyl residues, two galactose residues, one N-acetylglucosamine and a glucose residue at the reducing end.[CHEBI:59212]
term_xref : GlycoMotif:GGM.000115|GTC:G18625KA|GlycoEpitope:EP0069|CID:45266843|KEGG:G00117|CHEBI:59212
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 11
GQ1ba
term (main_entry) : GQ1ba
glycan_dictionary_accession : GSD000097
glytoucan_accession : G54733XO
term_in_sentence : A few studies have reported the association of autoantibodies to GM1 or GQ1bα with Alzheimer's disease (AD) or vascular dementia.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341] [https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341] [https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341] [https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341] [https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341]]]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341] [https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341] [https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341] [https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341] [https://pubmed.ncbi.nlm.nih.gov/25024341 25024341 25024341]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23717411 23717411 23717411] [https://pubmed.ncbi.nlm.nih.gov/23717411 23717411 23717411]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17870542 17870542 17870542] [https://pubmed.ncbi.nlm.nih.gov/17870542 17870542 17870542]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10702226 10702226 10702226] [https://pubmed.ncbi.nlm.nih.gov/10702226 10702226 10702226]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21137678 21137678 21137678] [https://pubmed.ncbi.nlm.nih.gov/21137678 21137678 21137678]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26748510 26748510 26748510] [https://pubmed.ncbi.nlm.nih.gov/26748510 26748510 26748510]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8662799 8662799 8662799] [https://pubmed.ncbi.nlm.nih.gov/8662799 8662799 8662799]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21274438 21274438 21274438] [https://pubmed.ncbi.nlm.nih.gov/21274438 21274438 21274438]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24649890 24649890 24649890] [https://pubmed.ncbi.nlm.nih.gov/24649890 24649890 24649890]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/16580208 16580208 16580208] [https://pubmed.ncbi.nlm.nih.gov/16580208 16580208 16580208]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28124591 28124591 28124591] [https://pubmed.ncbi.nlm.nih.gov/28124591 28124591 28124591]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20095613 20095613 20095613] [https://pubmed.ncbi.nlm.nih.gov/20095613 20095613 20095613]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17507233 17507233 17507233] [https://pubmed.ncbi.nlm.nih.gov/17507233 17507233 17507233]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23565921 23565921 23565921] [https://pubmed.ncbi.nlm.nih.gov/23565921 23565921 23565921]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/14505645 14505645 14505645] [https://pubmed.ncbi.nlm.nih.gov/14505645 14505645 14505645]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20930939 20930939 20930939] [https://pubmed.ncbi.nlm.nih.gov/20930939 20930939 20930939]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9201997 9201997 9201997] [https://pubmed.ncbi.nlm.nih.gov/9201997 9201997 9201997]]
definition :
term_xref : GlycoMotif:GGM.000116|GTC:G54733XO
synonyms : GQ1balpha
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
GQ1c
term (main_entry) : GQ1c
glycan_dictionary_accession : GSD000098
glytoucan_accession : G99524KA
term_in_sentence : The neural specific monoclonal antibody A2B5 was found to interact with GQ1c but not with Gq1b, nor did it interact with other glycolipids such as GM1, GD1a, GD1b, GT1a, GT1b and GA1.[PMID: [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6640289 6640289 6640289] [https://pubmed.ncbi.nlm.nih.gov/6640289 6640289 6640289]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6640289 6640289 6640289] [https://pubmed.ncbi.nlm.nih.gov/6640289 6640289 6640289]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6640289 6640289 6640289] [https://pubmed.ncbi.nlm.nih.gov/6640289 6640289 6640289]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7798936 7798936 7798936] [https://pubmed.ncbi.nlm.nih.gov/7798936 7798936 7798936]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7798936 7798936 7798936] [https://pubmed.ncbi.nlm.nih.gov/7798936 7798936 7798936]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1729139 1729139 1729139] [https://pubmed.ncbi.nlm.nih.gov/1729139 1729139 1729139]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20368669 20368669 20368669] [https://pubmed.ncbi.nlm.nih.gov/20368669 20368669 20368669]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2723647 2723647 2723647] [https://pubmed.ncbi.nlm.nih.gov/2723647 2723647 2723647]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2723647 2723647 2723647] [https://pubmed.ncbi.nlm.nih.gov/2723647 2723647 2723647]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1814411 1814411 1814411] [https://pubmed.ncbi.nlm.nih.gov/1814411 1814411 1814411]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3064875 3064875 3064875] [https://pubmed.ncbi.nlm.nih.gov/3064875 3064875 3064875]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3064875 3064875 3064875] [https://pubmed.ncbi.nlm.nih.gov/3064875 3064875 3064875]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3064875 3064875 3064875] [https://pubmed.ncbi.nlm.nih.gov/3064875 3064875 3064875]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3064875 3064875 3064875] [https://pubmed.ncbi.nlm.nih.gov/3064875 3064875 3064875]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6085330 6085330 6085330] [https://pubmed.ncbi.nlm.nih.gov/6085330 6085330 6085330]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1613492 1613492 1613492] [https://pubmed.ncbi.nlm.nih.gov/1613492 1613492 1613492]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1613492 1613492 1613492] [https://pubmed.ncbi.nlm.nih.gov/1613492 1613492 1613492]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17883393 17883393 17883393] [https://pubmed.ncbi.nlm.nih.gov/17883393 17883393 17883393]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11831845 11831845 11831845] [https://pubmed.ncbi.nlm.nih.gov/11831845 11831845 11831845]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11831845 11831845 11831845] [https://pubmed.ncbi.nlm.nih.gov/11831845 11831845 11831845]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11831845 11831845 11831845] [https://pubmed.ncbi.nlm.nih.gov/11831845 11831845 11831845]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11831845 11831845 11831845] [https://pubmed.ncbi.nlm.nih.gov/11831845 11831845 11831845]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425] [https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425] [https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425] [https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425] [https://pubmed.ncbi.nlm.nih.gov/10775425 10775425 10775425]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8219015 8219015 8219015] [https://pubmed.ncbi.nlm.nih.gov/8219015 8219015 8219015]]|8804704|1384262|[https://pubmed.ncbi.nlm.nih.gov/7066685 7066685 7066685]|2299192|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9613831 9613831 9613831] [https://pubmed.ncbi.nlm.nih.gov/9613831 9613831 9613831]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9613831 9613831 9613831] [https://pubmed.ncbi.nlm.nih.gov/9613831 9613831 9613831]]]|10350354|1304337|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9153001 9153001 9153001] [https://pubmed.ncbi.nlm.nih.gov/9153001 9153001 9153001]]|11959025|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578] [https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578] [https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2299350 2299350 2299350] [https://pubmed.ncbi.nlm.nih.gov/2299350 2299350 2299350]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776] [https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776] [https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494] [https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494] [https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494]]]|3942818|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12031286 12031286 12031286] [https://pubmed.ncbi.nlm.nih.gov/12031286 12031286 12031286]]|[https://pubmed.ncbi.nlm.nih.gov/7361620 7361620 7361620]
definition : Alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-[alpha-Neu5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)]-beta-D-Galp-(1->4)-beta-D-Glcp is a member of neuraminic acids and an amino octasaccharide.[CID:[https://pubmed.ncbi.nlm.nih.gov/91860352 91860352 91860352]]
term_xref : GlycoMotif:GGM.000117|GTC:G99524KA|CID:[https://pubmed.ncbi.nlm.nih.gov/91860352 91860352 91860352]|CHEBI:145645|KEGG:G00121
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 46
GT1a
term (main_entry) : GT1a
glycan_dictionary_accession : GSD000099
glytoucan_accession : G68110IF
term_in_sentence : GT1a mimicry was found in the lipo-oligosaccharides of strain ICDCCJ07002 and ICDCCJ07004; but a combination of GM3/GD3 mimics was observed in ICDCCJ07001, although this patient had anti-GT1a IgG antibodies.[PMID:[https://pubmed.ncbi.nlm.nih.gov/26197476 26197476 26197476]]
publication : 12023422|32623212|[https://pubmed.ncbi.nlm.nih.gov/26197476 26197476 26197476]|9585812|29747820|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/23804237 23804237 23804237] [https://pubmed.ncbi.nlm.nih.gov/23804237 23804237 23804237]]|11993188|31683059|19631994|9742882|29709941|8971119|8706663|893404|31829433|[https://pubmed.ncbi.nlm.nih.gov/8910600 8910600 8910600]|30600291|29319803|26176883|29063860|6766128|31602715|29808463|30711390|29847988|30116054|28187751
definition : A branched heptasaccharide derivative consisting of three sialyl residues, two galactose residues, one N-acetylglucosamine and a glucose residue at the reducing end.[CHEBI:59215]
term_xref : CID:45266863|GlycoMotif:GGM.000110|GTC:G68110IF|GlycoEpitope:EP0066|KEGG:G00112|CHEBI:59215
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
GT1a alpha
term (main_entry) : GT1a alpha
glycan_dictionary_accession : GSD000100
glytoucan_accession : G02149VR
term_in_sentence : A new class of gangliosides, GT1a alpha and GQ1b alpha, were initially identified as cholinergic neuron-specific antigens in bovine brain. [PMID:[https://pubmed.ncbi.nlm.nih.gov/8082783 8082783 8082783]]
publication : 7710562|[https://pubmed.ncbi.nlm.nih.gov/8082783 8082783 8082783]|10972137|9468624|9143254|8221098|9679279|11368158|11878808
definition :
term_xref : GlycoMotif:GGM.000111|GTC:G02149VR|GlycoEpitope:EP0111|CID:91851751|CHEBI:156678|KEGG:G00128
synonyms : GT1aa
function : GT1a alpha was a cholinerginic-specific antigen.[GlycoEpitope:EP0111]
disease_associations :
wikipedia :
essentials_of_glycobiology :
GT1b
term (main_entry) : GT1b
glycan_dictionary_accession : GSD000101
glytoucan_accession : G40183QN
term_in_sentence : GT1b ganglioside is axonally transported to the spinal cord dorsal horn and contributes to characteristics of neuropathic pain such as mechanical and thermal hypersensitivity.[PMID: [https://pubmed.ncbi.nlm.nih.gov/32030804 32030804 32030804]]
publication : [https://pubmed.ncbi.nlm.nih.gov/32030804 32030804 32030804]|26370787|32046393|9712688|7636307|9931455|25520869|19605473|17188834|10233751|22735313|20540782|22746533|1861141|19490186|9521848|11921200|10731661|31431523|15274627|32726962|12573517|18277613|11370834|11234774|11123278|18704164|16291967|11411041|27549393|25253868|22720883|10686582|11511306|29904724|31472390|19156870
definition : A branched amino heptasaccharide comprising a β-D-galactosyl-(1→4)-β-D-glucose disaccharide, the galactosyl residue of which carries an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl trisaccharide unit and an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl disaccharide unit through (2→4) and (2→3) linkages respectively. It corresponds to the carbohydrate portion of ganglioside GT1b.[CHEBI:59225]
term_xref : GlycoMotif:GGM.000112|GTC:G40183QN|GlycoEpitopeEP0067|CID:45266781|CHEBI:59225| GlycoGlycoEpitope:130680|SugarBind_Ligand:26|KEGG:G00116
synonyms :
function :
disease_associations : Toxoplasmosis[SugarBind_Ligand:26]|Lyme disease[SugarBind_Ligand:26]|Cholera[SugarBind_Ligand:26]|Botulism[SugarBind_Ligand:26]|Tetanus[SugarBind_Ligand:26]|Influenza[SugarBind_Ligand:26]
wikipedia :
essentials_of_glycobiology :
GT1c
term (main_entry) : GT1c
glycan_dictionary_accession : GSD000102
glytoucan_accession : G78818SP
term_in_sentence : We show here that VVH associates with ganglioside GM1a, Fucosyl-GM1, GD1a, GT1c, and GD1b by glycan array.[PMID: [https://pubmed.ncbi.nlm.nih.gov/32228455 32228455 32228455]]
publication : 28088450|30085356|[https://pubmed.ncbi.nlm.nih.gov/32228455 32228455 32228455]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656] [https://pubmed.ncbi.nlm.nih.gov/2468656 2468656 2468656]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19841910 19841910 19841910] [https://pubmed.ncbi.nlm.nih.gov/19841910 19841910 19841910]]|23877172|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858] [https://pubmed.ncbi.nlm.nih.gov/1695858 1695858 1695858]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776] [https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776] [https://pubmed.ncbi.nlm.nih.gov/10564776 10564776 10564776]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1613492 1613492 1613492] [https://pubmed.ncbi.nlm.nih.gov/1613492 1613492 1613492]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578] [https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578] [https://pubmed.ncbi.nlm.nih.gov/8474578 8474578 8474578]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/7798936 7798936 7798936] [https://pubmed.ncbi.nlm.nih.gov/7798936 7798936 7798936]]|11180643|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2723647 2723647 2723647] [https://pubmed.ncbi.nlm.nih.gov/2723647 2723647 2723647]]|[https://pubmed.ncbi.nlm.nih.gov/7066685 7066685 7066685]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9613831 9613831 9613831] [https://pubmed.ncbi.nlm.nih.gov/9613831 9613831 9613831]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9613831 9613831 9613831] [https://pubmed.ncbi.nlm.nih.gov/9613831 9613831 9613831]]]|[https://pubmed.ncbi.nlm.nih.gov/7361620 7361620 7361620]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494] [https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494] [https://pubmed.ncbi.nlm.nih.gov/10699494 10699494 10699494]]]
definition : A branched amino heptasaccharide consisting of a linear tetrasaccharide of β-D-galactose, N-acetyl-β-D-galactosamine, β-D-galactose and β-D-glucose residues linked sequentially (1→3), (1→4) and (1→4), to the galactose residue proximal to the reducing end is also linked (2→3) an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl trisaccharide side-chain. The carbohydrate moiety of ganglioside GT1c.[CHEBI:90509]
term_xref : GlycoMotif:GGM.000113|GTC:G78818SP|CID:91846734|CHEBI:90509|GlycoEpitope:EP0033|KEGG:G00120
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology :
GT2
term (main_entry) : GT2
glycan_dictionary_accession : GSD000103
glytoucan_accession : G36476BA
term_in_sentence : Biosynthesis of the c-series gangliosides GT3, GT2 and GP1c was studied in Golgi derived from rat liver.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]]]]
publication : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]]]|15498585|16005859|27540730|31533196|31201844
definition : A branched amino hexasaccharide consisting of a chain of three α-sialyl residues, a β-D-galactosyl residue and a β-D-glucose residue linked sequentially (2→8), (2→8), (2→3) and (1→4), to the galactosyl residue of which is also linked (1→4) an N-acetyl-β-D-galactosaminyl residue. The carbohydrate moiety of ganglioside GT2.[CHEBI:72446]
term_xref : GlycoMotif:GGM.000109|GTC:G36476BA|CID:70788971|CHEBI:72446|KEGG:G00119
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 11
GT3
term (main_entry) : GT3
glycan_dictionary_accession : GSD000104
glytoucan_accession : G93899SO
term_in_sentence : The purpose of this study was two-fold: (1) to formulate γ-tocotrienol (GT3) in a nanoemulsion formulation as a prophylactic orally administered radioprotective agent; and (2) to optimize the storage conditions to preserve the structural integrity of both the formulation and the compound.[PMID: [https://pubmed.ncbi.nlm.nih.gov/28029115 28029115 28029115]]
publication : [https://pubmed.ncbi.nlm.nih.gov/28029115 28029115 28029115]|31355968|30987413|27869747|27216753|8631981|29672891|10385047|29642403|10412028|27193023|30068561|23415908|8858920|2303428|27153057|27128741|2654294|26930378|7561885|25860286|30845647|24712339|30070965|[https://pubmed.ncbi.nlm.nih.gov/8910600 8910600 8910600]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358 1606358]]]]|27356050|8514740|18509108|23000517|29769046|29566611
definition : A linear amino pentasaccharide consisting of a chain of three α-sialyl residues, a β-D-galactosyl residue and a β-D-glucose residue linked sequentially (2→8), (2→8), (2→3) and (1→4).[CHEBI:72444]
term_xref : GlycoEpitope:EP0070|KEGG:G00118|CID:70788970|GlycoMotif:GGM.000092|GTC:G93899SO|CHEBI:72444
synonyms :
function :
disease_associations :
wikipedia :
essentials_of_glycobiology : Chapter 11