Testhyperlink123
3-Sialyl-LN (type 2)
term (main_entry) : 3-Sialyl-LN (type 2)
glycan_dictionary_accession : GSD000005
glytoucan_accession : G10203DW
term_in_sentence : Using new crystal structures, we also provide the atomic resolution basis for the differential recognition of 3′ and 6′SiaLacNAc1–4 (with the Galβ1–4 linkage known as Type 2 backbone16; Scheme 1) by TgMIC1-MARR, and make comparisons with the Type 1 chain isomer of 3′SiaLacNAc1–4 (designated 3′SiaLacNAc1–3).[PMID:19593815]
publication : 19593815|15659615|2414279|8586620|2111348|23747419
definition : A linear amino trisaccharide consisting of α-neuraminyl, β-D-galactosyl and N-acetyl-D-glucosamine residues linked in a (2→3) and (1→4) sequence.[CHEBI:52472]
term_xref : GTC:G10203DW|KEGG:G00253|SugarBind_Ligand:109|GlycoEpitope:EP0314|CHEBI:52472|GlycoMotif:GGM.000034
synonyms :
function :
disease_associations : Chronic gastritis[SugarBind_Ligand:109]|Toxoplasmosis[SugarBind_Ligand:109]|Peptic ulcers[SugarBind_Ligand:109]|Gastric cancer[SugarBind_Ligand:109]
wikipedia :
essentials_of_glycobiology :
High mannose
term (main_entry) : High mannose
glycan_dictionary_accession : GSD000108
glytoucan_accession : G55220VL
term_in_sentence : Each glycoform contained a number of peaks differing by 162 Da indicating heterogeneity and suggesting the presence of high-mannose sugars.[PMID: [https://pubmed.ncbi.nlm.nih.gov/11258925 11258925 11258925]]
publication : [https://pubmed.ncbi.nlm.nih.gov/11258925 11258925 11258925]| 17956937| 2059624| 2065054| 26791533| 4077844| 7780197| 9136890| 30659065| 30075362| 21421994| 31076349| 29738673| 29508223| 26747427| 30634645| 23007868| 29051951| 24549150| [https://pubmed.ncbi.nlm.nih.gov/12417032 12417032 12417032]| 26724786| 26956389| 26493153| 31102532| 29673624| 8348230| 25586968| 24975601| 29803109| 28465212| 25776945| 30151520| 21097542| 24326091| 27995699| 26003537| 6722291| 2925680| 25565276| 21460211| 25196214| 27387600| 22373601| 3729933| 16423983| 24174266| 30605318| 32371950
definition : An N-linked oligosaccharide that possesses between five and nine mannose residues attached to the chitobiose [(GlcNAc)2] core. [CHEBI:5717] None of the Man residues are substituted with any monosaccharide other than Man .
term_xref : GTC:G55220VL|CID: 70698382|CHEBI:71514
synonyms : oligomannose, high-mannose, oligomannose-type
function : Involved in promotion of protein folding in ER. [PMID: [https://pubmed.ncbi.nlm.nih.gov/12417032 12417032 12417032]].|High Man glycans are enriched at cell surface during apoptosis.[PMID: 17516205]
disease_associations : Relative abundance changes in multiple CDGs [PMID: 30770376][PMID: 28484880]
wikipedia :
essentials_of_glycobiology : Chapter 17
HNK-1
term (main_entry) : HNK-1
glycan_dictionary_accession : GSD000109
glytoucan_accession : G54406UD
term_in_sentence : The human natural killer-1 (HNK-1) carbohydrate, a unique trisaccharide possessing sulfated glucuronic acid in a non-reducing terminus (HSO3-3GlcAß1-3Galß1-4GlcNAc-), is highly expressed in the nervous system and its spatiotemporal expression is strictly regulated.[PMID: [https://pubmed.ncbi.nlm.nih.gov/28709864 28709864 28709864]]
publication : [https://pubmed.ncbi.nlm.nih.gov/28709864 28709864 28709864]| 31738061| 26738850| 30306736| 11070366| 20855890| 18024472| 22669261| 19729452| 19796667| 26850637| 11769463| 18263654| 15843379| 26659409| 9003039| 22087768| 21771787| 15173636| 9210489| 15258996| 17924534| 26382082| 16171882| 18802400| 9800516| 7504418| 11891229| 15232286| 9013478| 21621858| 11677051| 18668221| 11414798| 19265195| 8982638| 8798480| 28403522| 17935701| 1691305| 10998116| 9364602| 7528651| 12472892| 21176892| 28416698| 19389918| 28427937| 25450311
definition : An amino trisaccharide consisting of a 3-O-sulfo-β-D-glucuronic acid residue, a D-galactosyl residue and an N-acetyl-D-glucosamine residue (at the reducing end) in a linear sequence.[CHEBI:60322]
term_xref : GTC:G54406UD|GlycoEpitope:EP0001|CID: 46906103|CHEBI:60322|GlycoMotif:GGM.000058
synonyms : HNK-1 carbohydrate epitope| CD57|HNK-1 antigen
function : learning and memory[GlycoEpitope:EP0001]|neural crest cell migration[GlycoEpitope:EP0001]|neurite extension[GlycoEpitope:EP0001]|neuron-astrocyte adhesion[GlycoEpitope:EP0001]
disease_associations : schizophrenia-like psychosis[GlycoEpitope:EP0001]|neuropathy[GlycoEpitope:EP0001]|exfoliation syndrome[GlycoEpitope:EP0001]|secondary cataract[GlycoEpitope:EP0001]
wikipedia : https://en.wikipedia.org/wiki/N-linked_glycosylation
essentials_of_glycobiology : Chapter 17