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===GSD000101===
===GSD000151===
  '''term (main_entry)''' : GT1b <br>
[[File:G00054MO.png|thumb|G00054MO]]
  '''glycan_dictionary_accession''' : GSD000101 <br>
  '''term (main_entry)''' : Sialyl Lewis x <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G40183QN G40183QN] <br>
  '''glycan_dictionary_accession''' : GSD000151 <br>
  '''term_in_sentence''' : GT1b ganglioside is axonally transported to the spinal cord dorsal horn and contributes to characteristics of neuropathic pain such as mechanical and thermal hypersensitivity.[PMID: [https://pubmed.ncbi.nlm.nih.gov/32030804 32030804]] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G00054MO G00054MO] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/32030804 32030804]|[https://pubmed.ncbi.nlm.nih.gov/26370787 26370787]|[https://pubmed.ncbi.nlm.nih.gov/32046393 32046393]|[https://pubmed.ncbi.nlm.nih.gov/9712688 9712688]|[https://pubmed.ncbi.nlm.nih.gov/7636307 7636307]|[https://pubmed.ncbi.nlm.nih.gov/9931455 9931455]|[https://pubmed.ncbi.nlm.nih.gov/25520869 25520869]|[https://pubmed.ncbi.nlm.nih.gov/19605473 19605473]|[https://pubmed.ncbi.nlm.nih.gov/17188834 17188834]|[https://pubmed.ncbi.nlm.nih.gov/10233751 10233751]|[https://pubmed.ncbi.nlm.nih.gov/22735313 22735313]|[https://pubmed.ncbi.nlm.nih.gov/20540782 20540782]|[https://pubmed.ncbi.nlm.nih.gov/22746533 22746533]|[https://pubmed.ncbi.nlm.nih.gov/1861141 1861141]|[https://pubmed.ncbi.nlm.nih.gov/19490186 19490186]|[https://pubmed.ncbi.nlm.nih.gov/9521848 9521848]|[https://pubmed.ncbi.nlm.nih.gov/11921200 11921200]|[https://pubmed.ncbi.nlm.nih.gov/10731661 10731661]|[https://pubmed.ncbi.nlm.nih.gov/31431523 31431523]|[https://pubmed.ncbi.nlm.nih.gov/15274627 15274627]|[https://pubmed.ncbi.nlm.nih.gov/32726962 32726962]|[https://pubmed.ncbi.nlm.nih.gov/12573517 12573517]|[https://pubmed.ncbi.nlm.nih.gov/18277613 18277613]|[https://pubmed.ncbi.nlm.nih.gov/11370834 11370834]|[https://pubmed.ncbi.nlm.nih.gov/11234774 11234774]|[https://pubmed.ncbi.nlm.nih.gov/11123278 11123278]|[https://pubmed.ncbi.nlm.nih.gov/18704164 18704164]|[https://pubmed.ncbi.nlm.nih.gov/16291967 16291967]|[https://pubmed.ncbi.nlm.nih.gov/11411041 11411041]|[https://pubmed.ncbi.nlm.nih.gov/27549393 27549393]|[https://pubmed.ncbi.nlm.nih.gov/25253868 25253868]|[https://pubmed.ncbi.nlm.nih.gov/22720883 22720883]|[https://pubmed.ncbi.nlm.nih.gov/10686582 10686582]|[https://pubmed.ncbi.nlm.nih.gov/11511306 11511306]|[https://pubmed.ncbi.nlm.nih.gov/29904724 29904724]|[https://pubmed.ncbi.nlm.nih.gov/31472390 31472390]|[https://pubmed.ncbi.nlm.nih.gov/19156870 19156870] <br>
  '''term_in_sentence''' : As sialyl Lewis X is a lignad of the selectin family, it has been proposed that sialyl Lewis X-rich colon cancer cells metastasize to the liver by adhesion to selectins on hepatic endothelial cells.[PMID:[https://pubmed.ncbi.nlm.nih.gov/12828079 12828079]] <br>
  '''definition''' : A branched amino heptasaccharide comprising a β-D-galactosyl-(1→4)-β-D-glucose disaccharide, the galactosyl residue of which carries an N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl trisaccharide unit and an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl disaccharide unit through (2→4) and (2→3) linkages respectively. It corresponds to the carbohydrate portion of ganglioside GT1b.[CHEBI:59225] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/12828079 12828079]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8940172 8940172] [https://pubmed.ncbi.nlm.nih.gov/8940172 8940172]]|[https://pubmed.ncbi.nlm.nih.gov/10075923 10075923]|[https://pubmed.ncbi.nlm.nih.gov/19054801 19054801]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9642161 9642161] [https://pubmed.ncbi.nlm.nih.gov/9642161 9642161]]|[https://pubmed.ncbi.nlm.nih.gov/31054033 31054033]|[https://pubmed.ncbi.nlm.nih.gov/15229399 15229399]|[https://pubmed.ncbi.nlm.nih.gov/29061785 29061785]|[https://pubmed.ncbi.nlm.nih.gov/16033070 16033070]|[https://pubmed.ncbi.nlm.nih.gov/10728707 10728707]|[https://pubmed.ncbi.nlm.nih.gov/9556613 9556613]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8940172 8940172] [https://pubmed.ncbi.nlm.nih.gov/8940172 8940172]]|[https://pubmed.ncbi.nlm.nih.gov/9298692 9298692]|[https://pubmed.ncbi.nlm.nih.gov/18607721 18607721]|[https://pubmed.ncbi.nlm.nih.gov/22593503 22593503]|[https://pubmed.ncbi.nlm.nih.gov/25944902 25944902]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9642161 9642161] [https://pubmed.ncbi.nlm.nih.gov/9642161 9642161]]|[https://pubmed.ncbi.nlm.nih.gov/15780091 15780091]|[https://pubmed.ncbi.nlm.nih.gov/20401888 20401888] <br>
  '''term_xref''' : GlycoMotif:GGM.000112|GTC:G40183QN|GlycoEpitopeEP0067|CID:[https://pubmed.ncbi.nlm.nih.gov/45266781 45266781]|CHEBI:59225| GlycoGlycoEpitope:130680|SugarBind_Ligand:26|KEGG:G00116  <br>
'''definition''' : A sialylated version of Lewis X antigen expressed on cell surfaces with structure alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-beta-D-GlcpNAcis α-Neup5Ac-(2→3)-β-D-Galp-(1→4)-[α-L-Fucp-(1→3)]-D-GlcpNAc in which the anomeric configuration of the reducing-end N-acetyl-beta-D-glucosamine residue is beta. It is a ligand for selectins. [MESH:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2030970 2030970] [https://pubmed.ncbi.nlm.nih.gov/2030970 2030970]],CHEI:71622] <br>
'''synonyms''' :  <br>
'''term_xref''' : GTC:G00054MO |GlycoEpitope:EP0012|CID:[https://pubmed.ncbi.nlm.nih.gov/44456859 44456859]|CHEBI:71622|MESH:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2030970 2030970] [https://pubmed.ncbi.nlm.nih.gov/2030970 2030970]]|GlycoMotif:GGM.000022  <br>
'''function''' :  <br>
  '''synonyms''' : SLe(x)|SLe^x|SLex|Slex <br>
  '''disease_associations''' : Toxoplasmosis[SugarBind_Ligand:26]|Lyme disease[SugarBind_Ligand:26]|Cholera[SugarBind_Ligand:26]|Botulism[SugarBind_Ligand:26]|Tetanus[SugarBind_Ligand:26]|Influenza[SugarBind_Ligand:26] <br>
  '''function''' : Sialyl Lex was shown to be a specific ligand on human leukocytes for vascular E- and P-selectins,and was shown to mediate leukocyte recruitment.[GlycoEpitope:EP0012]|The determinant is also frequently expressed on human cancer cells,and is involved in the adhesion of cancer cells to vascular endothelium and thus contribute to hematogenous metastasis of cancer.[GlycoEpitope:EP0012] <br>
  '''disease_associations''' : colon cancer[GlycoEpitope:EP0012]|colorectal cancer[GlycoEpitope:EP0012] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000102===
===GSD000152===
[[File:G78818SP.png|thumb|G78818SP]]
  '''term (main_entry)''' : Sialyl Lewis x-i <br>
  '''term (main_entry)''' : GT1c <br>
  '''glycan_dictionary_accession''' : GSD000152 <br>
  '''glycan_dictionary_accession''' : GSD000102 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G06597DS G06597DS] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G78818SP G78818SP] <br>
  '''term_in_sentence''' : Univariate analysis showed that survival of NSCLC patients with high (more than 100 units/ml) sialyl Lewis X-i antigen levels was significantly poorer than that of patients with low antigen levels (P = 0.0001).[PMID:[https://pubmed.ncbi.nlm.nih.gov/9815711 9815711]] <br>
  '''term_in_sentence''' : We show here that VVH associates with ganglioside GM1a, Fucosyl-GM1, GD1a, GT1c, and GD1b by glycan array.[PMID: [https://pubmed.ncbi.nlm.nih.gov/32228455 32228455]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/9815711 9815711]|[https://pubmed.ncbi.nlm.nih.gov/9730796 9730796]|[https://pubmed.ncbi.nlm.nih.gov/11867833 11867833]|[https://pubmed.ncbi.nlm.nih.gov/9713476 9713476]|[https://pubmed.ncbi.nlm.nih.gov/2819663 2819663]|[https://pubmed.ncbi.nlm.nih.gov/9372327 9372327]|[https://pubmed.ncbi.nlm.nih.gov/9615762 9615762]|[https://pubmed.ncbi.nlm.nih.gov/1352835 1352835]|[https://pubmed.ncbi.nlm.nih.gov/2575680 2575680]|[https://pubmed.ncbi.nlm.nih.gov/9330526 9330526]|[https://pubmed.ncbi.nlm.nih.gov/8753037 8753037]|[https://pubmed.ncbi.nlm.nih.gov/2210805 2210805]|[https://pubmed.ncbi.nlm.nih.gov/12680155 12680155]|[https://pubmed.ncbi.nlm.nih.gov/11974864 11974864]|[https://pubmed.ncbi.nlm.nih.gov/10453898 10453898]|[https://pubmed.ncbi.nlm.nih.gov/2565704 2565704]|[https://pubmed.ncbi.nlm.nih.gov/17144590 17144590] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/28088450 28088450]|[https://pubmed.ncbi.nlm.nih.gov/30085356 30085356]|[https://pubmed.ncbi.nlm.nih.gov/32228455 32228455]|[https://pubmed.ncbi.nlm.nih.gov/2468656 2468656]|[https://pubmed.ncbi.nlm.nih.gov/19841910 19841910]|[https://pubmed.ncbi.nlm.nih.gov/23877172 23877172]|[https://pubmed.ncbi.nlm.nih.gov/1695858 1695858]|[https://pubmed.ncbi.nlm.nih.gov/10564776 10564776]|[https://pubmed.ncbi.nlm.nih.gov/1613492 1613492]|[https://pubmed.ncbi.nlm.nih.gov/8474578 8474578]|[https://pubmed.ncbi.nlm.nih.gov/7798936 7798936]|[https://pubmed.ncbi.nlm.nih.gov/11180643 11180643]|[https://pubmed.ncbi.nlm.nih.gov/2723647 2723647]|[https://pubmed.ncbi.nlm.nih.gov/7066685 7066685]|[https://pubmed.ncbi.nlm.nih.gov/9613831 9613831]|[https://pubmed.ncbi.nlm.nih.gov/7361620 7361620]|[https://pubmed.ncbi.nlm.nih.gov/10699494 10699494] <br>
  '''definition''' : <br>
  '''definition''' : A branched amino heptasaccharide consisting of a linear tetrasaccharide of β-D-galactose, N-acetyl-β-D-galactosamine, β-D-galactose and β-D-glucose residues linked sequentially (1→3), (1→4) and (1→4), to the galactose residue proximal to the reducing end is also linked (2→3) an N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl trisaccharide side-chain. The carbohydrate moiety of ganglioside GT1c.[CHEBI:90509] <br>
  '''term_xref''' : GTC:G06597DS|GlycoEpitope:EP0043|CID:[https://pubmed.ncbi.nlm.nih.gov/91855346 91855346]|CHEBI:147019 <br>
  '''term_xref''' : GlycoMotif:GGM.000113|GTC:G78818SP|CID:[https://pubmed.ncbi.nlm.nih.gov/91846734 91846734]|CHEBI:90509|GlycoEpitope:EP0033|KEGG:G00120 <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' : <br>
  '''function''' : hematogenous metastasis[GlycoEpitope:EP0043]|the progression of inflammation[GlycoEpitope:EP0043] <br>
  '''disease_associations''' : <br>
  '''disease_associations''' : lung cancer[GlycoEpitope:EP0043]|ovarian cancer[GlycoEpitope:EP0043]|pancreatic adenocarcinoma[GlycoEpitope:EP0043] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000103===
===GSD000153===
  '''term (main_entry)''' : GT2 <br>
  '''term (main_entry)''' : Sialyl T antigen <br>
  '''glycan_dictionary_accession''' : GSD000103 <br>
  '''glycan_dictionary_accession''' : GSD000153 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G36476BA G36476BA] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G65562ZE G65562ZE] <br>
  '''term_in_sentence''' : Biosynthesis of the c-series gangliosides GT3, GT2 and GP1c was studied in Golgi derived from rat liver.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358]]] <br>
  '''term_in_sentence''' : The expression and functional analysis of the sialyl-T antigen in prostate cancer.[PMID:[https://pubmed.ncbi.nlm.nih.gov/32583304 32583304]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358]]|[https://pubmed.ncbi.nlm.nih.gov/15498585 15498585]|[https://pubmed.ncbi.nlm.nih.gov/16005859 16005859]|[https://pubmed.ncbi.nlm.nih.gov/27540730 27540730]|[https://pubmed.ncbi.nlm.nih.gov/31533196 31533196]|[https://pubmed.ncbi.nlm.nih.gov/31201844 31201844] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/32583304 32583304]|[https://pubmed.ncbi.nlm.nih.gov/31897478 31897478]|[https://pubmed.ncbi.nlm.nih.gov/31719620 31719620]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10365852 10365852] [https://pubmed.ncbi.nlm.nih.gov/10365852 10365852]]|[https://pubmed.ncbi.nlm.nih.gov/25727149 25727149]|[https://pubmed.ncbi.nlm.nih.gov/11523928 11523928]|[https://pubmed.ncbi.nlm.nih.gov/20407596 20407596]|[https://pubmed.ncbi.nlm.nih.gov/25464017 25464017]|[https://pubmed.ncbi.nlm.nih.gov/30864133 30864133]|[https://pubmed.ncbi.nlm.nih.gov/26391208 26391208]|[https://pubmed.ncbi.nlm.nih.gov/19811634 19811634]|[https://pubmed.ncbi.nlm.nih.gov/29796594 29796594]|[https://pubmed.ncbi.nlm.nih.gov/23725156 23725156]|[https://pubmed.ncbi.nlm.nih.gov/8905873 8905873]|[https://pubmed.ncbi.nlm.nih.gov/11192238 11192238]|[https://pubmed.ncbi.nlm.nih.gov/18275089 18275089]|[https://pubmed.ncbi.nlm.nih.gov/27037304 27037304]|[https://pubmed.ncbi.nlm.nih.gov/11949946 11949946]|[https://pubmed.ncbi.nlm.nih.gov/15604091 15604091]|[https://pubmed.ncbi.nlm.nih.gov/24118321 24118321] <br>
  '''definition''' : A branched amino hexasaccharide consisting of a chain of three α-sialyl residues, a β-D-galactosyl residue and a β-D-glucose residue linked sequentially (2→8), (2→8), (2→3) and (1→4), to the galactosyl residue of which is also linked (1→4) an N-acetyl-β-D-galactosaminyl residue. The carbohydrate moiety of ganglioside GT2.[CHEBI:72446] <br>
  '''definition''' : Alpha-Neup5Ac-(2→3)-beta-D-Galp-(1→3)-alpha-D-GalpNAc is alpha-Neup5Ac-(2→3)-beta-D-Galp-(1→3)-D-GalpNAc in which the configuration at the GalNAc anomeric carbon is alpha. It has a role as an epitope.[CHEBI:65257] <br>
  '''term_xref''' : GlycoMotif:GGM.000109|GTC:G36476BA|CID:[https://pubmed.ncbi.nlm.nih.gov/70788971 70788971]|CHEBI:72446|KEGG:G00119  <br>
  '''term_xref''' : GlycoMotif:GGM.000013|GTC:G65562ZE|CID:[https://pubmed.ncbi.nlm.nih.gov/44611726 44611726]|CHEBI:65257<br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453016/ Chapter 11]<br>
  '''essentials_of_glycobiology''' : <br>




===GSD000104===
===GSD000154===
  '''term (main_entry)''' : GT3 <br>
  '''term (main_entry)''' : Sialylated biantennary <br>
  '''glycan_dictionary_accession''' : GSD000104 <br>
  '''glycan_dictionary_accession''' : GSD000154 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G93899SO G93899SO] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : The purpose of this study was two-fold: (1) to formulate γ-tocotrienol (GT3) in a nanoemulsion formulation as a prophylactic orally administered radioprotective agent; and (2) to optimize the storage conditions to preserve the structural integrity of both the formulation and the compound.[PMID: [https://pubmed.ncbi.nlm.nih.gov/28029115 28029115]] <br>
  '''term_in_sentence''' : Simbucus nigra agglutinin or an antibody specific to sialylated lactosamine with a preference for Neu5Acalpha2-6Gal rather than Neu5Acalpha2-3Gal reduced sperm binding to oviduct isthmic cells, as did occupying putative receptors on sperm with sialylated biantennary glycans.[PMID:[https://pubmed.ncbi.nlm.nih.gov/23115267 23115267]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/28029115 28029115]|[https://pubmed.ncbi.nlm.nih.gov/31355968 31355968]|[https://pubmed.ncbi.nlm.nih.gov/30987413 30987413]|[https://pubmed.ncbi.nlm.nih.gov/27869747 27869747]|[https://pubmed.ncbi.nlm.nih.gov/27216753 27216753]|[https://pubmed.ncbi.nlm.nih.gov/8631981 8631981]|[https://pubmed.ncbi.nlm.nih.gov/29672891 29672891]|[https://pubmed.ncbi.nlm.nih.gov/10385047 10385047]|[https://pubmed.ncbi.nlm.nih.gov/29642403 29642403]|[https://pubmed.ncbi.nlm.nih.gov/10412028 10412028]|[https://pubmed.ncbi.nlm.nih.gov/27193023 27193023]|[https://pubmed.ncbi.nlm.nih.gov/30068561 30068561]|[https://pubmed.ncbi.nlm.nih.gov/23415908 23415908]|[https://pubmed.ncbi.nlm.nih.gov/8858920 8858920]|[https://pubmed.ncbi.nlm.nih.gov/2303428 2303428]|[https://pubmed.ncbi.nlm.nih.gov/27153057 27153057]|[https://pubmed.ncbi.nlm.nih.gov/27128741 27128741]|[https://pubmed.ncbi.nlm.nih.gov/2654294 2654294]|[https://pubmed.ncbi.nlm.nih.gov/26930378 26930378]|[https://pubmed.ncbi.nlm.nih.gov/7561885 7561885]|[https://pubmed.ncbi.nlm.nih.gov/25860286 25860286]|[https://pubmed.ncbi.nlm.nih.gov/30845647 30845647]|[https://pubmed.ncbi.nlm.nih.gov/24712339 24712339]|[https://pubmed.ncbi.nlm.nih.gov/30070965 30070965]|[https://pubmed.ncbi.nlm.nih.gov/8910600 8910600]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1606358 1606358] [https://pubmed.ncbi.nlm.nih.gov/1606358 1606358]]|[https://pubmed.ncbi.nlm.nih.gov/27356050 27356050]|[https://pubmed.ncbi.nlm.nih.gov/8514740 8514740]|[https://pubmed.ncbi.nlm.nih.gov/18509108 18509108]|[https://pubmed.ncbi.nlm.nih.gov/23000517 23000517]|[https://pubmed.ncbi.nlm.nih.gov/29769046 29769046]|[https://pubmed.ncbi.nlm.nih.gov/29566611 29566611] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/23115267 23115267]|[https://pubmed.ncbi.nlm.nih.gov/31510952 31510952]|[https://pubmed.ncbi.nlm.nih.gov/29265394 29265394]|[https://pubmed.ncbi.nlm.nih.gov/31589880 31589880]|[https://pubmed.ncbi.nlm.nih.gov/3979568 3979568]|[https://pubmed.ncbi.nlm.nih.gov/26045275 26045275]|[https://pubmed.ncbi.nlm.nih.gov/29029079 29029079]|[https://pubmed.ncbi.nlm.nih.gov/30252064 30252064] <br>
  '''definition''' : A linear amino pentasaccharide consisting of a chain of three α-sialyl residues, a β-D-galactosyl residue and a β-D-glucose residue linked sequentially (2→8), (2→8), (2→3) and (1→4).[CHEBI:72444] <br>
  '''definition''' : A binantennary glycan with one or two sialic acid residues as non-reducing terminal residues on one or both antennae. [RN] <br>
  '''term_xref''' : GlycoEpitope:EP0070|KEGG:G00118|CID:[https://pubmed.ncbi.nlm.nih.gov/70788970 70788970]|GlycoMotif:GGM.000092|GTC:G93899SO|CHEBI:72444 <br>
  '''term_xref''' :  <br>
  '''synonyms''' : <br>
  '''synonyms''' : sialyl biantennary <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453016/ Chapter 11]<br>
  '''essentials_of_glycobiology''' : <br>




===GSD000105===
===GSD000155===
[[File:G94435QH.png|thumb|G94435QH]]
  '''term (main_entry)''' : Sialylated complex-type <br>
  '''term (main_entry)''' : Blood group H (Type 3) <br>
  '''glycan_dictionary_accession''' : GSD000155 <br>
'''glycan_dictionary_accession''' : GSD000105 <br>
'''glytoucan_accession ''' :  [https://glygen.org/glycan/G94435QH G94435QH]<br>
'''term_in_sentence''' : One particular lambody, VLRB.aGPA.23, was shown by glycan array analysis to be selective for the blood group H type 3 trisaccharide (BG-H3, Fucα1-2Galβ1-3GalNAcα), aGPA, and TFα (Galβ1-3GalNAcα), with affinity constants of 0.2, 1, and 8 nM, respectively.[PMID:[https://pubmed.ncbi.nlm.nih.gov/23030719 23030719]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/23030719 23030719]|[https://pubmed.ncbi.nlm.nih.gov/20466654 20466654]|[https://pubmed.ncbi.nlm.nih.gov/1563908 1563908]|[https://pubmed.ncbi.nlm.nih.gov/3944092 3944092]|[https://pubmed.ncbi.nlm.nih.gov/11218748 11218748]|[https://pubmed.ncbi.nlm.nih.gov/11101633 11101633]|[https://pubmed.ncbi.nlm.nih.gov/18842005 18842005]|[https://pubmed.ncbi.nlm.nih.gov/27550195 27550195]|[https://pubmed.ncbi.nlm.nih.gov/2469783 2469783]|[https://pubmed.ncbi.nlm.nih.gov/2433836 2433836]|[https://pubmed.ncbi.nlm.nih.gov/23118206 23118206]|[https://pubmed.ncbi.nlm.nih.gov/8445257 8445257]|[https://pubmed.ncbi.nlm.nih.gov/2664192 2664192]|[https://pubmed.ncbi.nlm.nih.gov/3063304 3063304] <br>
'''definition''' :  <br>
'''term_xref''' :  GlycoMotif:GGM.000010|GTC:G94435QH<br>
'''synonyms''' : H type 3|H antigen (type 3)|Type 3 chain H <br>
'''function''' :  <br>
'''disease_associations''' :  <br>
'''wikipedia''' :  <br>
'''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453016/ Chapter 11]<br>
 
 
===GSD000106===
'''term (main_entry)''' : Heparan sulfate <br>
  '''glycan_dictionary_accession''' : GSD000106 <br>
  '''glytoucan_accession ''' :  <br>
  '''glytoucan_accession ''' :  <br>
  '''term_in_sentence''' : In Niemann-Pick C-1 fibroblasts, where deaminative degradation of heparan sulfate is defective, carbonylated proteins were abundant.[PMID: 17540770] <br>
  '''term_in_sentence''' : By using 1H-NMR spectroscopy we were able to establish that our product contains a single N-linked biantennary , fully sialylated complex-type oligosaccharide , typical of human hepatomas.[PMID:[https://pubmed.ncbi.nlm.nih.gov/1694115 1694115]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/32266657 32266657]|[https://pubmed.ncbi.nlm.nih.gov/29554552 29554552]|[https://pubmed.ncbi.nlm.nih.gov/29032302 29032302]|[https://pubmed.ncbi.nlm.nih.gov/30003471 30003471]|[https://pubmed.ncbi.nlm.nih.gov/25197032 25197032]|[https://pubmed.ncbi.nlm.nih.gov/28538085 28538085]|[https://pubmed.ncbi.nlm.nih.gov/26236728 26236728]|[https://pubmed.ncbi.nlm.nih.gov/16917509 16917509]|[https://pubmed.ncbi.nlm.nih.gov/22899865 22899865]|[https://pubmed.ncbi.nlm.nih.gov/17080204 17080204]|[https://pubmed.ncbi.nlm.nih.gov/23042481 23042481]|[https://pubmed.ncbi.nlm.nih.gov/28982096 28982096]|[https://pubmed.ncbi.nlm.nih.gov/24146040 24146040]|[https://pubmed.ncbi.nlm.nih.gov/25081076 25081076]|[https://pubmed.ncbi.nlm.nih.gov/15719168 15719168]|[https://pubmed.ncbi.nlm.nih.gov/17453622 17453622]|[https://pubmed.ncbi.nlm.nih.gov/25325954 25325954]|[https://pubmed.ncbi.nlm.nih.gov/21110089 21110089]|[https://pubmed.ncbi.nlm.nih.gov/29797526 29797526]|[https://pubmed.ncbi.nlm.nih.gov/21967329 21967329]|[https://pubmed.ncbi.nlm.nih.gov/23313092 23313092]|[https://pubmed.ncbi.nlm.nih.gov/11212344 11212344]|[https://pubmed.ncbi.nlm.nih.gov/28465034 28465034]|[https://pubmed.ncbi.nlm.nih.gov/11746174 11746174]|[https://pubmed.ncbi.nlm.nih.gov/12512855 12512855]|[https://pubmed.ncbi.nlm.nih.gov/8836040 8836040]|[https://pubmed.ncbi.nlm.nih.gov/28394734 28394734]|[https://pubmed.ncbi.nlm.nih.gov/24182748 24182748]|[https://pubmed.ncbi.nlm.nih.gov/28264929 28264929]|[https://pubmed.ncbi.nlm.nih.gov/28745308 28745308]|[https://pubmed.ncbi.nlm.nih.gov/26555370 26555370]|[https://pubmed.ncbi.nlm.nih.gov/14718374 14718374]|[https://pubmed.ncbi.nlm.nih.gov/16767693 16767693]|[https://pubmed.ncbi.nlm.nih.gov/25246018 25246018]|[https://pubmed.ncbi.nlm.nih.gov/19584012 19584012]|[https://pubmed.ncbi.nlm.nih.gov/8274190 8274190]|[https://pubmed.ncbi.nlm.nih.gov/25034023 25034023]|[https://pubmed.ncbi.nlm.nih.gov/8370471 8370471]|[https://pubmed.ncbi.nlm.nih.gov/26571620 26571620]|[https://pubmed.ncbi.nlm.nih.gov/29920400 29920400]|[https://pubmed.ncbi.nlm.nih.gov/31731076 31731076]|[https://pubmed.ncbi.nlm.nih.gov/20816205 20816205]|[https://pubmed.ncbi.nlm.nih.gov/16880267 16880267]|[https://pubmed.ncbi.nlm.nih.gov/31547957 31547957]|[https://pubmed.ncbi.nlm.nih.gov/11457867 11457867]|[https://pubmed.ncbi.nlm.nih.gov/27241222 27241222]|[https://pubmed.ncbi.nlm.nih.gov/28718936 28718936]|[https://pubmed.ncbi.nlm.nih.gov/21204109 21204109]|[https://pubmed.ncbi.nlm.nih.gov/31016560 31016560]|[https://pubmed.ncbi.nlm.nih.gov/11166215 11166215]|[https://pubmed.ncbi.nlm.nih.gov/11457866 11457866] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/1694115 1694115]|[https://pubmed.ncbi.nlm.nih.gov/15201278 15201278]|[https://pubmed.ncbi.nlm.nih.gov/30471292 30471292]|[https://pubmed.ncbi.nlm.nih.gov/30969765 30969765]|[https://pubmed.ncbi.nlm.nih.gov/11058758 11058758]|[https://pubmed.ncbi.nlm.nih.gov/28342150 28342150] <br>
  '''definition''' : A linear polysaccharide in which the backbone consists of a variably sulfated repeating disaccharide unit.[CHEBI:28815] <br>
  '''definition''' : Complex N-linked glycan that have added GlcNAc residues at both the α-3 and α-6 mannose sites and do not contain mannose residues apart from the core structure but with sialic acid residues. <br>
  '''term_xref''' : CHEBI:28815|CID: [https://pubmed.ncbi.nlm.nih.gov/53477715 53477715]|GlycoEpitope: EP0086 <br>
  '''term_xref''' : <br>
  '''synonyms''' : Heparan N-sulfate|Heparan sulfate|Heparan sulphate|Heparatan sulfate|Heparin monosulfate| Heparin sulfate|Heparitin monosulfate|Heparitin sulfate|N-Acetylheparan sulfate <br>
  '''synonyms''' : sialo-complex type <br>
  '''function''' : Heparan sulfate proteoglycans (HSPGs) play crucial roles regulating key developmental signaling pathways, such as the Wnt, Hedgehog, transforming growth factor-beta, and fibroblast growth factor pathways.[GlycoEpitope: EP0086] <br>
  '''function''' : enhance the signaling activity of soluble intercellular adhesion molecule-1 in mouse astrocytes [PMID: [https://pubmed.ncbi.nlm.nih.gov/15201278 15201278]] Appears in IgG-Fc.[PMID:[https://pubmed.ncbi.nlm.nih.gov/20647032 20647032] ] <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453030/ Chapter 10]<br>




===GSD000107===
===GSD000156===
  '''term (main_entry)''' : Heparin <br>
  '''term (main_entry)''' : Sialylated tetraantennary <br>
  '''glycan_dictionary_accession''' : GSD000107 <br>
  '''glycan_dictionary_accession''' : GSD000156 <br>
  '''glytoucan_accession ''' :  <br>
  '''glytoucan_accession ''' :  <br>
  '''term_in_sentence''' : Two cellulose-based membranes, containing 5 and 20% N, N-diethyl-aminoethyl cellulose (DEAE) respectively, were investigated for ionic attachment of heparin and heparin release.[PMID:[https://pubmed.ncbi.nlm.nih.gov/6416324 6416324]] <br>
  '''term_in_sentence''' : A small amount of sialylated tetraantennary oligosaccharide was detected.[PMID:[https://pubmed.ncbi.nlm.nih.gov/16321355 16321355]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/27100512 27100512]|[https://pubmed.ncbi.nlm.nih.gov/22566218 22566218]|[https://pubmed.ncbi.nlm.nih.gov/27264866 27264866]|[https://pubmed.ncbi.nlm.nih.gov/30094590 30094590]|[https://pubmed.ncbi.nlm.nih.gov/31077659 31077659]|[https://pubmed.ncbi.nlm.nih.gov/26975675 26975675]|[https://pubmed.ncbi.nlm.nih.gov/2083874 2083874]|[https://pubmed.ncbi.nlm.nih.gov/25088334 25088334]|[https://pubmed.ncbi.nlm.nih.gov/3333067 3333067]|[https://pubmed.ncbi.nlm.nih.gov/2191809 2191809]|[https://pubmed.ncbi.nlm.nih.gov/28118750 28118750]|[https://pubmed.ncbi.nlm.nih.gov/28224913 28224913]|[https://pubmed.ncbi.nlm.nih.gov/22495506 22495506]|[https://pubmed.ncbi.nlm.nih.gov/29385025 29385025]|[https://pubmed.ncbi.nlm.nih.gov/10332503 10332503]|[https://pubmed.ncbi.nlm.nih.gov/22393937 22393937]|[https://pubmed.ncbi.nlm.nih.gov/19947315 19947315]|[https://pubmed.ncbi.nlm.nih.gov/27655335 27655335]|[https://pubmed.ncbi.nlm.nih.gov/14529394 14529394]|[https://pubmed.ncbi.nlm.nih.gov/2419035 2419035]|[https://pubmed.ncbi.nlm.nih.gov/22048616 22048616]|[https://pubmed.ncbi.nlm.nih.gov/23849978 23849978]|[https://pubmed.ncbi.nlm.nih.gov/10204652 10204652]|[https://pubmed.ncbi.nlm.nih.gov/28958760 28958760]|[https://pubmed.ncbi.nlm.nih.gov/12627673 12627673]|[https://pubmed.ncbi.nlm.nih.gov/9042555 9042555]|[https://pubmed.ncbi.nlm.nih.gov/15639107 15639107]|[https://pubmed.ncbi.nlm.nih.gov/28880550 28880550]|[https://pubmed.ncbi.nlm.nih.gov/27238483 27238483]|[https://pubmed.ncbi.nlm.nih.gov/1964668 1964668]|[https://pubmed.ncbi.nlm.nih.gov/16716101 16716101]|[https://pubmed.ncbi.nlm.nih.gov/10796377 10796377]|[https://pubmed.ncbi.nlm.nih.gov/25981976 25981976]|[https://pubmed.ncbi.nlm.nih.gov/24680753 24680753]|[https://pubmed.ncbi.nlm.nih.gov/2191118 2191118]|[https://pubmed.ncbi.nlm.nih.gov/21166465 21166465]|[https://pubmed.ncbi.nlm.nih.gov/30582884 30582884]|[https://pubmed.ncbi.nlm.nih.gov/1322434 1322434]|[https://pubmed.ncbi.nlm.nih.gov/15330727 15330727]|[https://pubmed.ncbi.nlm.nih.gov/9752370 9752370]|[https://pubmed.ncbi.nlm.nih.gov/6416324 6416324]|[https://pubmed.ncbi.nlm.nih.gov/14996629 14996629]|[https://pubmed.ncbi.nlm.nih.gov/20452241 20452241]|[https://pubmed.ncbi.nlm.nih.gov/1340407 1340407]|[https://pubmed.ncbi.nlm.nih.gov/29050610 29050610]|345399|[https://pubmed.ncbi.nlm.nih.gov/6916469 6916469]|[https://pubmed.ncbi.nlm.nih.gov/6565376 6565376]|[https://pubmed.ncbi.nlm.nih.gov/26714061 26714061] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/16321355 16321355]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1940447 1940447] [https://pubmed.ncbi.nlm.nih.gov/1940447 1940447]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27501865 27501865] [https://pubmed.ncbi.nlm.nih.gov/27501865 27501865]] <br>
  '''definition''' : A highly sulfated linear glycosaminoglycan comprising complex patterns of uronic acid-(1→4)-D-glucosamine repeating subunits. Used as an injectable anticoagulant, it has the highest negative charge density of any known biological molecule.[CHEBI:28304] <br>
  '''definition''' : A tetraantennary glycan with four GlcNAc branches linked to the core and the addition of one sialic acid residues. <br>
  '''term_xref''' : CID:772|CHEBI:28304 <br>
  '''term_xref''' :  <br>
  '''synonyms''' : bemiparin|bemiparin|certoparin|Cy 222|enoxaparin|fluxum|Heparin|Heparinic acid|parnaparin|reviparin|sandoparin <br>
  '''synonyms''' : <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
Line 107: Line 91:




===GSD000108===
===GSD000157===
  '''term (main_entry)''' : High mannose <br>
  '''term (main_entry)''' : Sialyl-Tn antigen <br>
  '''glycan_dictionary_accession''' : GSD000108 <br>
  '''glycan_dictionary_accession''' : GSD000157 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G55220VL G55220VL] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G36123IU G36123IU] <br>
  '''term_in_sentence''' : Each glycoform contained a number of peaks differing by 162 Da indicating heterogeneity and suggesting the presence of high-mannose sugars.[PMID:[https://pubmed.ncbi.nlm.nih.gov/11258925 11258925]] <br>
  '''term_in_sentence''' : The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-β secretion from monocytes/macrophages through the DAP12-Syk pathway.[PMID:[https://pubmed.ncbi.nlm.nih.gov/23035012 23035012]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/11258925 11258925]|[https://pubmed.ncbi.nlm.nih.gov/17956937 17956937]|[https://pubmed.ncbi.nlm.nih.gov/2059624 2059624]|[https://pubmed.ncbi.nlm.nih.gov/2065054 2065054]|[https://pubmed.ncbi.nlm.nih.gov/26791533 26791533]|[https://pubmed.ncbi.nlm.nih.gov/4077844 4077844]|[https://pubmed.ncbi.nlm.nih.gov/7780197 7780197]|[https://pubmed.ncbi.nlm.nih.gov/9136890 9136890]|[https://pubmed.ncbi.nlm.nih.gov/30659065 30659065]|[https://pubmed.ncbi.nlm.nih.gov/30075362 30075362]|[https://pubmed.ncbi.nlm.nih.gov/21421994 21421994]|[https://pubmed.ncbi.nlm.nih.gov/31076349 31076349]|[https://pubmed.ncbi.nlm.nih.gov/29738673 29738673]|[https://pubmed.ncbi.nlm.nih.gov/29508223 29508223]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26747427 26747427] [https://pubmed.ncbi.nlm.nih.gov/26747427 26747427]]|[https://pubmed.ncbi.nlm.nih.gov/30634645 30634645]|[https://pubmed.ncbi.nlm.nih.gov/23007868 23007868]|[https://pubmed.ncbi.nlm.nih.gov/29051951 29051951]|[https://pubmed.ncbi.nlm.nih.gov/24549150 24549150]|[https://pubmed.ncbi.nlm.nih.gov/12417032 12417032]|[https://pubmed.ncbi.nlm.nih.gov/26724786 26724786]|[https://pubmed.ncbi.nlm.nih.gov/26956389 26956389]|[https://pubmed.ncbi.nlm.nih.gov/26493153 26493153]|[https://pubmed.ncbi.nlm.nih.gov/31102532 31102532]|[https://pubmed.ncbi.nlm.nih.gov/29673624 29673624]|[https://pubmed.ncbi.nlm.nih.gov/8348230 8348230]|[https://pubmed.ncbi.nlm.nih.gov/25586968 25586968]|[https://pubmed.ncbi.nlm.nih.gov/24975601 24975601]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29803109 29803109] [https://pubmed.ncbi.nlm.nih.gov/29803109 29803109]]|[https://pubmed.ncbi.nlm.nih.gov/28465212 28465212]|[https://pubmed.ncbi.nlm.nih.gov/25776945 25776945]|[https://pubmed.ncbi.nlm.nih.gov/30151520 30151520]|[https://pubmed.ncbi.nlm.nih.gov/21097542 21097542]|[https://pubmed.ncbi.nlm.nih.gov/24326091 24326091]|[https://pubmed.ncbi.nlm.nih.gov/27995699 27995699]|[https://pubmed.ncbi.nlm.nih.gov/26003537 26003537]|[https://pubmed.ncbi.nlm.nih.gov/6722291 6722291]|[https://pubmed.ncbi.nlm.nih.gov/2925680 2925680]|[https://pubmed.ncbi.nlm.nih.gov/25565276 25565276]|[https://pubmed.ncbi.nlm.nih.gov/21460211 21460211]|[https://pubmed.ncbi.nlm.nih.gov/25196214 25196214]|[https://pubmed.ncbi.nlm.nih.gov/27387600 27387600]|[https://pubmed.ncbi.nlm.nih.gov/22373601 22373601]|[https://pubmed.ncbi.nlm.nih.gov/3729933 3729933]|[https://pubmed.ncbi.nlm.nih.gov/16423983 16423983]|[https://pubmed.ncbi.nlm.nih.gov/24174266 24174266]|[https://pubmed.ncbi.nlm.nih.gov/30605318 30605318] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/23035012 23035012]|[https://pubmed.ncbi.nlm.nih.gov/29273237 29273237]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15770530 15770530] [https://pubmed.ncbi.nlm.nih.gov/15770530 15770530]]|[https://pubmed.ncbi.nlm.nih.gov/31595388 31595388]|[https://pubmed.ncbi.nlm.nih.gov/26617889 26617889]|[https://pubmed.ncbi.nlm.nih.gov/1720922 1720922]|[https://pubmed.ncbi.nlm.nih.gov/15466199 15466199]|[https://pubmed.ncbi.nlm.nih.gov/10971172 10971172]|[https://pubmed.ncbi.nlm.nih.gov/14652017 14652017]|[https://pubmed.ncbi.nlm.nih.gov/8616877 8616877]|[https://pubmed.ncbi.nlm.nih.gov/1543361 1543361]|[https://pubmed.ncbi.nlm.nih.gov/16965854 16965854]|[https://pubmed.ncbi.nlm.nih.gov/21566901 21566901]|[https://pubmed.ncbi.nlm.nih.gov/9269833 9269833]|[https://pubmed.ncbi.nlm.nih.gov/9834267 9834267]|[https://pubmed.ncbi.nlm.nih.gov/24970145 24970145]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22367369 22367369] [https://pubmed.ncbi.nlm.nih.gov/22367369 22367369]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10778170 10778170] [https://pubmed.ncbi.nlm.nih.gov/10778170 10778170]]|[https://pubmed.ncbi.nlm.nih.gov/30018351 30018351]|[https://pubmed.ncbi.nlm.nih.gov/28628803 28628803]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/16149605 16149605] [https://pubmed.ncbi.nlm.nih.gov/16149605 16149605]]|[https://pubmed.ncbi.nlm.nih.gov/32134186 32134186]|[https://pubmed.ncbi.nlm.nih.gov/28632300 28632300]|[https://pubmed.ncbi.nlm.nih.gov/11308020 11308020]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10365852 10365852] [https://pubmed.ncbi.nlm.nih.gov/10365852 10365852]]|[https://pubmed.ncbi.nlm.nih.gov/17195456 17195456]|[https://pubmed.ncbi.nlm.nih.gov/23567325 23567325]|[https://pubmed.ncbi.nlm.nih.gov/11014575 11014575]|[https://pubmed.ncbi.nlm.nih.gov/2342728 2342728]|[https://pubmed.ncbi.nlm.nih.gov/8575847 8575847]|[https://pubmed.ncbi.nlm.nih.gov/1851822 1851822]|[https://pubmed.ncbi.nlm.nih.gov/11735169 11735169]|[https://pubmed.ncbi.nlm.nih.gov/20960853 20960853]|[https://pubmed.ncbi.nlm.nih.gov/7846011 7846011] <br>
  '''definition''' : An N-linked oligosaccharide that possesses between five and nine mannose residues attached to the chitobiose [(GlcNAc)2] core. [CHEBI:5717] None of the Man residues are substituted with any monosaccharide other than Man . <br>
  '''definition''' : N-acetyl-alpha-neuraminyl-(2→6)-N-acetyl-alpha-D-galactosamine is an N-acetyl-alpha-neuraminyl-(2→6)-N-acetyl-D-galactosamine in which the carbon bearing the anomeric hydroxy group has alpha configuration. It has a role as an epitope. It derives from a N-acetyl-alpha-D-galactosamine and a N-acetyl-alpha-neuraminic acid.[CHEBI:61818] <br>
  '''term_xref''' : GTC:G55220VL|CID:[https://pubmed.ncbi.nlm.nih.gov/70698382 70698382]|CHEBI:71514 <br>
  '''term_xref''' : GTC:G36123IU|GlycoEpitope:EP0022|CID:[https://pubmed.ncbi.nlm.nih.gov/51351800 51351800]|CHEBI:61818 <br>
  '''synonyms''' : oligomannose <br>
  '''synonyms''' : <br>
  '''function''' : Involved in promotion of protein folding in ER. [PMID:[https://pubmed.ncbi.nlm.nih.gov/12417032 12417032]].|High Man glycans are enriched at cell surface during apoptosis.[PMID: 17516205] <br>
  '''function''' : apoptosis of monocyte-derived dendritic cells[GlycoEpitope:EP0022]|decrease of adhesion and increase of migration[GlycoEpitope:EP0022]|increase of tumor growth[GlycoEpitope:EP0022]|associated with morphological changes, decreased growth and increased migration of MDA-MB-231 cells.[GlycoEpitope:EP0022] <br>
  '''disease_associations''' : Relative abundance changes in multiple CDGs [PMID: 30770376][PMID: 28484880] <br>
  '''disease_associations''' : anaplastic meningioma[GlycoEpitope:EP0022]|Barrett's esophagus[GlycoEpitope:EP0022]|bladder cancer[GlycoEpitope:EP0022]|breast cancer[GlycoEpitope:EP0022]|colon cancer[GlycoEpitope:EP0022]|colorectal cancer[GlycoEpitope:EP0022]|erythroblastic leukemia[GlycoEpitope:EP0022]|esophageal cancer[GlycoEpitope:EP0022]|gastric cancer[GlycoEpitope:EP0022]|helicobacter pylori chronic gastritis(HpCG)[GlycoEpitope:EP0022]|liver cancer[GlycoEpitope:EP0022]|iterome cancer[GlycoEpitope:EP0022]|ovary tumor[GlycoEpitope:EP0022]|pancreas cancer[GlycoEpitope:EP0022] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453033/ Chapter 17]<br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453027/ Chapter 56]<br>




===GSD000109===
===GSD000158===
  '''term (main_entry)''' : HNK-1 <br>
  '''term (main_entry)''' : SLex Core 2 O-glycan <br>
  '''glycan_dictionary_accession''' : GSD000109 <br>
  '''glycan_dictionary_accession''' : GSD000158 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G54406UD G54406UD] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G97345NY G97345NY] <br>
  '''term_in_sentence''' : The human natural killer-1 (HNK-1) carbohydrate, a unique trisaccharide possessing sulfated glucuronic acid in a non-reducing terminus (HSO3-3GlcAß1-3Galß1-4GlcNAc-), is highly expressed in the nervous system and its spatiotemporal expression is strictly regulated.[PMID:[https://pubmed.ncbi.nlm.nih.gov/28709864 28709864]] <br>
  '''term_in_sentence''' : In particular, the sLeX-modified core 2 O-glycan structure C2-O-sLeX has been directly demonstrated to confer significantly higher affinity selectin binding than sLeX.[PMID:[https://pubmed.ncbi.nlm.nih.gov/15596301 15596301]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/28709864 28709864]|[https://pubmed.ncbi.nlm.nih.gov/31738061 31738061]|[https://pubmed.ncbi.nlm.nih.gov/26738850 26738850]|[https://pubmed.ncbi.nlm.nih.gov/30306736 30306736]|[https://pubmed.ncbi.nlm.nih.gov/11070366 11070366]|[https://pubmed.ncbi.nlm.nih.gov/20855890 20855890]|[https://pubmed.ncbi.nlm.nih.gov/18024472 18024472]|[https://pubmed.ncbi.nlm.nih.gov/22669261 22669261]|[https://pubmed.ncbi.nlm.nih.gov/19729452 19729452]|[https://pubmed.ncbi.nlm.nih.gov/19796667 19796667]|[https://pubmed.ncbi.nlm.nih.gov/26850637 26850637]|[https://pubmed.ncbi.nlm.nih.gov/11769463 11769463]|[https://pubmed.ncbi.nlm.nih.gov/18263654 18263654]|[https://pubmed.ncbi.nlm.nih.gov/15843379 15843379]|[https://pubmed.ncbi.nlm.nih.gov/26659409 26659409]|[https://pubmed.ncbi.nlm.nih.gov/9003039 9003039]|[https://pubmed.ncbi.nlm.nih.gov/22087768 22087768]|[https://pubmed.ncbi.nlm.nih.gov/21771787 21771787]|[https://pubmed.ncbi.nlm.nih.gov/15173636 15173636]|[https://pubmed.ncbi.nlm.nih.gov/9210489 9210489]|[https://pubmed.ncbi.nlm.nih.gov/15258996 15258996]|[https://pubmed.ncbi.nlm.nih.gov/17924534 17924534]|[https://pubmed.ncbi.nlm.nih.gov/26382082 26382082]|[https://pubmed.ncbi.nlm.nih.gov/16171882 16171882]|[https://pubmed.ncbi.nlm.nih.gov/18802400 18802400]|[https://pubmed.ncbi.nlm.nih.gov/9800516 9800516]|[https://pubmed.ncbi.nlm.nih.gov/7504418 7504418]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11891229 11891229] [https://pubmed.ncbi.nlm.nih.gov/11891229 11891229]]|[https://pubmed.ncbi.nlm.nih.gov/15232286 15232286]|[https://pubmed.ncbi.nlm.nih.gov/9013478 9013478]|[https://pubmed.ncbi.nlm.nih.gov/21621858 21621858]|[https://pubmed.ncbi.nlm.nih.gov/11677051 11677051]|[https://pubmed.ncbi.nlm.nih.gov/18668221 18668221]|[https://pubmed.ncbi.nlm.nih.gov/11414798 11414798]|[https://pubmed.ncbi.nlm.nih.gov/19265195 19265195]|[https://pubmed.ncbi.nlm.nih.gov/8982638 8982638]|[https://pubmed.ncbi.nlm.nih.gov/8798480 8798480]|[https://pubmed.ncbi.nlm.nih.gov/28403522 28403522]|[https://pubmed.ncbi.nlm.nih.gov/17935701 17935701]|[https://pubmed.ncbi.nlm.nih.gov/1691305 1691305]|[https://pubmed.ncbi.nlm.nih.gov/10998116 10998116]|[https://pubmed.ncbi.nlm.nih.gov/9364602 9364602]|[https://pubmed.ncbi.nlm.nih.gov/7528651 7528651]|[https://pubmed.ncbi.nlm.nih.gov/12472892 12472892]|[https://pubmed.ncbi.nlm.nih.gov/21176892 21176892]|[https://pubmed.ncbi.nlm.nih.gov/28416698 28416698]|[https://pubmed.ncbi.nlm.nih.gov/19389918 19389918]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28427937 28427937] [https://pubmed.ncbi.nlm.nih.gov/28427937 28427937]]|[https://pubmed.ncbi.nlm.nih.gov/25450311 25450311] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/15596301 15596301] <br>
  '''definition''' : An amino trisaccharide consisting of a 3-O-sulfo-β-D-glucuronic acid residue, a D-galactosyl residue and an N-acetyl-D-glucosamine residue (at the reducing end) in a linear sequence.[CHEBI:60322] <br>
  '''definition''' : <br>
  '''term_xref''' : GTC:G54406UD|GlycoEpitope:EP0001|CID:[https://pubmed.ncbi.nlm.nih.gov/46906103 46906103]|CHEBI:60322|GlycoMotif:GGM.000058 <br>
  '''term_xref''' : GlycoMotif:GGM.000053|GTC:G97345NY <br>
'''synonyms''' : HNK-1 carbohydrate epitope| CD57|HNK-1 antigen <br>
  '''synonyms''' : SLe^x Core 2 O-glycan <br>
'''function''' : learning and memory[GlycoEpitope:EP0001]|neural crest cell migration[GlycoEpitope:EP0001]|neurite extension[GlycoEpitope:EP0001]|neuron-astrocyte adhesion[GlycoEpitope:EP0001] <br>
  '''disease_associations''' : schizophrenia-like psychosis[GlycoEpitope:EP0001]|neuropathy[GlycoEpitope:EP0001]|exfoliation syndrome[GlycoEpitope:EP0001]|secondary cataract[GlycoEpitope:EP0001] <br>
  '''wikipedia''' : https://en.wikipedia.org/wiki/N-linked_glycosylation <br>
'''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453033/ Chapter 17]<br>
 
 
===GSD000110===
'''term (main_entry)''' : Hybrid <br>
'''glycan_dictionary_accession''' : GSD000110 <br>
'''glytoucan_accession ''' : [https://www.glygen.org/glycan/G16828VN G16828VN] <br>
'''term_in_sentence''' : A hybrid-type N-glycan was accessed by total synthesis, converted to an oxazoline, and used as a donor substrate with both wild type Endo M and an N175Q glycosynthase Endo M mutant allowing the convergent synthesis of a glycosylated amino acid bearing a hybrid N-glycan structure. [PMID:[https://pubmed.ncbi.nlm.nih.gov/27058295 27058295]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/27058295 27058295]|[https://pubmed.ncbi.nlm.nih.gov/15044398 15044398]|[https://pubmed.ncbi.nlm.nih.gov/28714086 28714086]|[https://pubmed.ncbi.nlm.nih.gov/29578688 29578688]|[https://pubmed.ncbi.nlm.nih.gov/26999365 26999365] <br>
'''definition''' : An N-linked glycan in which the Manα1-6 arm of the trimannosyl core Manα1-3(Manα1-6)Manβ1-4GlcNAcβ1–4GlcNAcβ1–Asn-X-Ser/Thr is substituted by one or more additional Man residues and the Manα1-3 arm is substituted by a GlcNAc residue added by GlcNAcT1. The GlcNAc linked to the a3 Man can be extended in the same manner as any complex glycan antenna. The trimannosyl core can also be core fucosylated and/or bisected by the addition of a GlcNAc to the 3 position of the α-linked Man residue.[Essentials of Glycobiology:[https://www.ncbi.nlm.nih.gov/books/NBK453020/ Chapter 9]] <br>
'''term_xref''' : GTC:G16828VN|CID:[https://pubmed.ncbi.nlm.nih.gov/91847108 91847108]|CHEBI:147471 <br>
'''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453020/ Chapter 9]<br>
  '''essentials_of_glycobiology''' : <br>




===GSD000111===
===GSD000159===
  '''term (main_entry)''' : i antigen <br>
  '''term (main_entry)''' : SSEA-1 <br>
  '''glycan_dictionary_accession''' : GSD000111 <br>
  '''glycan_dictionary_accession''' : GSD000159 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G00058MO G00058MO]|[https://www.glygen.org/glycan/G46055MA G46055MA] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G85497PI G85497PI] <br>
  '''term_in_sentence''' : Inasmuch as the hybridoma was established by hybridization of lymphocytes derived from regional lymph nodes of lung cancer, and the antigen was found in the patient's lung cancer tissue, the i antigen in lung cancer is probably recognized as a tumor-associated antigen by the host's immune cell system.[PMID:[https://pubmed.ncbi.nlm.nih.gov/2422274 2422274]] <br>
  '''term_in_sentence''' : Our findings suggest that expression of SSEA-1 immunoreactivity in thyroid neoplasms was associated with more aggressive thyroid carcinomas.[PMID:[https://pubmed.ncbi.nlm.nih.gov/27550342 27550342]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/2422274 2422274]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15679458 15679458] [https://pubmed.ncbi.nlm.nih.gov/15679458 15679458]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21912254 21912254] [https://pubmed.ncbi.nlm.nih.gov/21912254 21912254]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12468428 12468428] [https://pubmed.ncbi.nlm.nih.gov/12468428 12468428]]|[https://pubmed.ncbi.nlm.nih.gov/28508465 28508465]|[https://pubmed.ncbi.nlm.nih.gov/6203982 6203982]|[https://pubmed.ncbi.nlm.nih.gov/30728302 30728302]|[https://pubmed.ncbi.nlm.nih.gov/8449405 8449405]|[https://pubmed.ncbi.nlm.nih.gov/9122902 9122902]|[https://pubmed.ncbi.nlm.nih.gov/10360315 10360315]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6159787 6159787] [https://pubmed.ncbi.nlm.nih.gov/6159787 6159787]]|[https://pubmed.ncbi.nlm.nih.gov/6183759 6183759]|518539|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6715951 6715951] [https://pubmed.ncbi.nlm.nih.gov/6715951 6715951]]|[https://pubmed.ncbi.nlm.nih.gov/21933024 21933024] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/27550342 27550342]|[https://pubmed.ncbi.nlm.nih.gov/25564944 25564944]|[https://pubmed.ncbi.nlm.nih.gov/30987116 30987116]|[https://pubmed.ncbi.nlm.nih.gov/10778174 10778174]|[https://pubmed.ncbi.nlm.nih.gov/19427293 19427293]|[https://pubmed.ncbi.nlm.nih.gov/24923741 24923741]|[https://pubmed.ncbi.nlm.nih.gov/28092949 28092949]|[https://pubmed.ncbi.nlm.nih.gov/16499901 16499901]|[https://pubmed.ncbi.nlm.nih.gov/10470652 10470652]|[https://pubmed.ncbi.nlm.nih.gov/18787210 18787210]|[https://pubmed.ncbi.nlm.nih.gov/2885312 2885312]|[https://pubmed.ncbi.nlm.nih.gov/16149609 16149609]|[https://pubmed.ncbi.nlm.nih.gov/17003364 17003364]|[https://pubmed.ncbi.nlm.nih.gov/27363517 27363517]|[https://pubmed.ncbi.nlm.nih.gov/15505339 15505339]|[https://pubmed.ncbi.nlm.nih.gov/27990704 27990704]|[https://pubmed.ncbi.nlm.nih.gov/2568298 2568298]|[https://pubmed.ncbi.nlm.nih.gov/20491542 20491542]|[https://pubmed.ncbi.nlm.nih.gov/23572256 23572256]|[https://pubmed.ncbi.nlm.nih.gov/1977666 1977666]|[https://pubmed.ncbi.nlm.nih.gov/9553168 9553168]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20458727 20458727] [https://pubmed.ncbi.nlm.nih.gov/20458727 20458727]]|[https://pubmed.ncbi.nlm.nih.gov/2566639 2566639]|[https://pubmed.ncbi.nlm.nih.gov/14577357 14577357]|[https://pubmed.ncbi.nlm.nih.gov/20960856 20960856]|[https://pubmed.ncbi.nlm.nih.gov/15547746 15547746]|[https://pubmed.ncbi.nlm.nih.gov/9096265 9096265]|[https://pubmed.ncbi.nlm.nih.gov/30639212 30639212]|[https://pubmed.ncbi.nlm.nih.gov/1357195 1357195]|[https://pubmed.ncbi.nlm.nih.gov/1359630 1359630]|[https://pubmed.ncbi.nlm.nih.gov/20181261 20181261]|[https://pubmed.ncbi.nlm.nih.gov/20508065 20508065]|[https://pubmed.ncbi.nlm.nih.gov/2907526 2907526]|[https://pubmed.ncbi.nlm.nih.gov/22624699 22624699]|[https://pubmed.ncbi.nlm.nih.gov/22988836 22988836]|[https://pubmed.ncbi.nlm.nih.gov/17183690 17183690]|[https://pubmed.ncbi.nlm.nih.gov/27188587 27188587]|[https://pubmed.ncbi.nlm.nih.gov/7908065 7908065]|[https://pubmed.ncbi.nlm.nih.gov/10400391 10400391]|[https://pubmed.ncbi.nlm.nih.gov/6137429 6137429]|[https://pubmed.ncbi.nlm.nih.gov/1979260 1979260]|[https://pubmed.ncbi.nlm.nih.gov/2898921 2898921]|[https://pubmed.ncbi.nlm.nih.gov/14736812 14736812]|[https://pubmed.ncbi.nlm.nih.gov/30919971 30919971] <br>
  '''definition''' :  <br>
  '''definition''' :  <br>
  '''term_xref''' : GlycoMotif:GGM.000004|GlycoMotif:GGM.000002|GTC:G46055MA|GTC:G00058MO <br>
  '''term_xref''' : GTC:G85497PI |GlycoEpitope:EP0042|CID:[https://pubmed.ncbi.nlm.nih.gov/91851144 91851144]|CHEBI:154343  <br>
  '''synonyms''' : Type 2 LN2 <br>
  '''synonyms''' : <br>
  '''function''' : <br>
  '''function''' : This determinant is specifically recognized by the antibody raised against stage-specific embryonic antigen-1 (SSEA-1)[GlycoEpitope:EP0042]. The SSEA-1 antibody requires Lex hapten carried by i-antigenic structure (e.g.,nor-nLc6Cer).[GlycoEpitope:EP0042] <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453030/ Chapter 10]<br>




===GSD000112===
===GSD000160===
  '''term (main_entry)''' : I antigen <br>
  '''term (main_entry)''' : SSEA-3 <br>
  '''glycan_dictionary_accession''' : GSD000112 <br>
  '''glycan_dictionary_accession''' : GSD000160 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G56045WU G56045WU] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G25129BT G25129BT] <br>
  '''term_in_sentence''' : The I antigen is formed by the action of an enzyme (a glycosyltransferase), which adds branches onto the i antigen.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15679458 15679458] [https://pubmed.ncbi.nlm.nih.gov/15679458 15679458]]] <br>
  '''term_in_sentence''' : Glycosphingolipids (GSLs), such as the globo-series GSLs stage-specific embryonic antigen 3 (SSEA-3), SSEA-4, and Globo-H, are specifically expressed on pluripotent stem cells and cancer cells, and are known to be associated with various biological processes such as cell recognition, cell adhesion, and signal transduction.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31817926 31817926] [https://pubmed.ncbi.nlm.nih.gov/31817926 31817926]]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15679458 15679458] [https://pubmed.ncbi.nlm.nih.gov/15679458 15679458]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21912254 21912254] [https://pubmed.ncbi.nlm.nih.gov/21912254 21912254]]|[https://pubmed.ncbi.nlm.nih.gov/30705292 30705292]|[https://pubmed.ncbi.nlm.nih.gov/33403394 33403394]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6715951 6715951] [https://pubmed.ncbi.nlm.nih.gov/6715951 6715951]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12468428 12468428] [https://pubmed.ncbi.nlm.nih.gov/12468428 12468428]]|[https://pubmed.ncbi.nlm.nih.gov/6088627 6088627]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/6159787 6159787] [https://pubmed.ncbi.nlm.nih.gov/6159787 6159787]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31817926 31817926] [https://pubmed.ncbi.nlm.nih.gov/31817926 31817926]]|[https://pubmed.ncbi.nlm.nih.gov/30271856 30271856]|[https://pubmed.ncbi.nlm.nih.gov/32684574 32684574]|[https://pubmed.ncbi.nlm.nih.gov/26677875 26677875]|[https://pubmed.ncbi.nlm.nih.gov/23175153 23175153]|[https://pubmed.ncbi.nlm.nih.gov/32525407 32525407]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29227830 29227830] [https://pubmed.ncbi.nlm.nih.gov/29227830 29227830]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18773292 18773292] [https://pubmed.ncbi.nlm.nih.gov/18773292 18773292]]|[https://pubmed.ncbi.nlm.nih.gov/25561682 25561682]|[https://pubmed.ncbi.nlm.nih.gov/10837462 10837462]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2412924 2412924] [https://pubmed.ncbi.nlm.nih.gov/2412924 2412924]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21149348 21149348] [https://pubmed.ncbi.nlm.nih.gov/21149348 21149348]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17008424 17008424] [https://pubmed.ncbi.nlm.nih.gov/17008424 17008424]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2874662 2874662] [https://pubmed.ncbi.nlm.nih.gov/2874662 2874662]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25171543 25171543] [https://pubmed.ncbi.nlm.nih.gov/25171543 25171543]]|[https://pubmed.ncbi.nlm.nih.gov/31304790 31304790]|[https://pubmed.ncbi.nlm.nih.gov/31642560 31642560]|[https://pubmed.ncbi.nlm.nih.gov/30484221 30484221]|[https://pubmed.ncbi.nlm.nih.gov/30525067 30525067]|[https://pubmed.ncbi.nlm.nih.gov/21161592 21161592]|[https://pubmed.ncbi.nlm.nih.gov/27325407 27325407]|[https://pubmed.ncbi.nlm.nih.gov/28170296 28170296]|[https://pubmed.ncbi.nlm.nih.gov/29637816 29637816]|[https://pubmed.ncbi.nlm.nih.gov/27318475 27318475]|[https://pubmed.ncbi.nlm.nih.gov/31346146 31346146]|[https://pubmed.ncbi.nlm.nih.gov/7648586 7648586]|[https://pubmed.ncbi.nlm.nih.gov/24236059 24236059]|[https://pubmed.ncbi.nlm.nih.gov/21964054 21964054]|[https://pubmed.ncbi.nlm.nih.gov/27456773 27456773]|[https://pubmed.ncbi.nlm.nih.gov/30558911 30558911]|[https://pubmed.ncbi.nlm.nih.gov/21559451 21559451]|[https://pubmed.ncbi.nlm.nih.gov/29312455 29312455]|[https://pubmed.ncbi.nlm.nih.gov/27549315 27549315]|[https://pubmed.ncbi.nlm.nih.gov/30599359 30599359]|[https://pubmed.ncbi.nlm.nih.gov/6141938 6141938]|[https://pubmed.ncbi.nlm.nih.gov/28883415 28883415]|[https://pubmed.ncbi.nlm.nih.gov/30733757 30733757]|[https://pubmed.ncbi.nlm.nih.gov/26041528 26041528]|[https://pubmed.ncbi.nlm.nih.gov/16643871 16643871] <br>
  '''definition''' : N-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4S,5S,6R)-4-[(2R,3R,4R,5S,6R)-3-Acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-[[(2R,3R,4R,5S,6R)-3-acetamido-4-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,5-dihydroxyoxan-2-yl]oxy-2,4-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide (CHEBI:151390) is a amino sugar.[CHEBI:151390] <br>
  '''definition''' : An amino trisaccharide consisting of β-D-galactopyranose, 2-acetamido-2-deoxy-β-D-galactopyranose and α-D-galactopyranose residues joined in sequence by (1→3) glycosidic linkages.[CHEBI:149071] <br>
  '''term_xref''' : GlycoMotif:GGM.000003|GlycoEpitope:EP0138|GTC:G56045WU|CID:[https://pubmed.ncbi.nlm.nih.gov/91852915 91852915]|CHEBI:151390 <br>
  '''term_xref''' : GTC:G25129BT|GlycoEpitope:EP0039|CID:[https://pubmed.ncbi.nlm.nih.gov/91855781 91855781]|CHEBI:149071|GlycoMotif:GGM.000079  <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' : <br>
  '''disease_associations''' : embryonal carcinoma[GlycoEpitope:EP0039]|teratocarcinoma[GlycoEpitope:EP0039]|yolk sac carcinoma[GlycoEpitope:EP0039] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453020/ Chapter 9]<br>
  '''essentials_of_glycobiology''' : <br>




===GSD000113===
===GSD000161===
  '''term (main_entry)''' : Isoglobotetraosylceramide <br>
  '''term (main_entry)''' : SSEA-4 <br>
  '''glycan_dictionary_accession''' : GSD000113 <br>
  '''glycan_dictionary_accession''' : GSD000161 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G57710SU G57710SU] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G84263XI G84263XI] <br>
  '''term_in_sentence''' : Furthermore, isoglobotetraosylceramide seems to play a direct role in the metastatic process since the blocking of exposed antigen with monoclonal antibodies, or their Fab fragments, results in a highly significant decrease in lung colony formation.[PMID:[https://pubmed.ncbi.nlm.nih.gov/8504431 8504431]] <br>
  '''term_in_sentence''' : Glycosphingolipids (GSLs), such as the globo-series GSLs stage-specific embryonic antigen 3 (SSEA-3), SSEA-4, and Globo-H, are specifically expressed on pluripotent stem cells and cancer cells, and are known to be associated with various biological processes such as cell recognition, cell adhesion, and signal transduction.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31817926 31817926] [https://pubmed.ncbi.nlm.nih.gov/31817926 31817926]]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/1396705 1396705]|[https://pubmed.ncbi.nlm.nih.gov/8504431 8504431]|[https://pubmed.ncbi.nlm.nih.gov/2713378 2713378]|[https://pubmed.ncbi.nlm.nih.gov/3489485 3489485]|[https://pubmed.ncbi.nlm.nih.gov/18997175 18997175]|[https://pubmed.ncbi.nlm.nih.gov/7053385 7053385]|[https://pubmed.ncbi.nlm.nih.gov/3379797 3379797]|[https://pubmed.ncbi.nlm.nih.gov/2465279 2465279]|[https://pubmed.ncbi.nlm.nih.gov/3743633 3743633]|[https://pubmed.ncbi.nlm.nih.gov/11479210 11479210] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/27845370 27845370]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31817926 31817926] [https://pubmed.ncbi.nlm.nih.gov/31817926 31817926]]|[https://pubmed.ncbi.nlm.nih.gov/26295543 26295543]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25171543 25171543] [https://pubmed.ncbi.nlm.nih.gov/25171543 25171543]]|[https://pubmed.ncbi.nlm.nih.gov/25978997 25978997]|[https://pubmed.ncbi.nlm.nih.gov/30296654 30296654]|[https://pubmed.ncbi.nlm.nih.gov/25853231 25853231]|[https://pubmed.ncbi.nlm.nih.gov/24862940 24862940]|[https://pubmed.ncbi.nlm.nih.gov/31243630 31243630]|[https://pubmed.ncbi.nlm.nih.gov/28736232 28736232]|[https://pubmed.ncbi.nlm.nih.gov/22895512 22895512]|[https://pubmed.ncbi.nlm.nih.gov/24578244 24578244]|[https://pubmed.ncbi.nlm.nih.gov/29478902 29478902]|[https://pubmed.ncbi.nlm.nih.gov/23574147 23574147]|[https://pubmed.ncbi.nlm.nih.gov/23768762 23768762]|[https://pubmed.ncbi.nlm.nih.gov/27797400 27797400]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29227830 29227830] [https://pubmed.ncbi.nlm.nih.gov/29227830 29227830]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18773292 18773292] [https://pubmed.ncbi.nlm.nih.gov/18773292 18773292]]|[https://pubmed.ncbi.nlm.nih.gov/25123923 25123923]|[https://pubmed.ncbi.nlm.nih.gov/22924692 22924692]|[https://pubmed.ncbi.nlm.nih.gov/22665977 22665977]|[https://pubmed.ncbi.nlm.nih.gov/23330736 23330736]|[https://pubmed.ncbi.nlm.nih.gov/31831622 31831622]|[https://pubmed.ncbi.nlm.nih.gov/31916611 31916611]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2412924 2412924] [https://pubmed.ncbi.nlm.nih.gov/2412924 2412924]]|[https://pubmed.ncbi.nlm.nih.gov/16033656 16033656]|[https://pubmed.ncbi.nlm.nih.gov/24866102 24866102]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20458727 20458727] [https://pubmed.ncbi.nlm.nih.gov/20458727 20458727]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21149348 21149348] [https://pubmed.ncbi.nlm.nih.gov/21149348 21149348]]|[https://pubmed.ncbi.nlm.nih.gov/26940129 26940129]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/17008424 17008424] [https://pubmed.ncbi.nlm.nih.gov/17008424 17008424]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2874662 2874662] [https://pubmed.ncbi.nlm.nih.gov/2874662 2874662]]|[https://pubmed.ncbi.nlm.nih.gov/23301556 23301556]|[https://pubmed.ncbi.nlm.nih.gov/27836003 27836003]|[https://pubmed.ncbi.nlm.nih.gov/19118716 19118716]|[https://pubmed.ncbi.nlm.nih.gov/24550271 24550271]|[https://pubmed.ncbi.nlm.nih.gov/32988880 32988880]|[https://pubmed.ncbi.nlm.nih.gov/22743677 22743677]|[https://pubmed.ncbi.nlm.nih.gov/20683402 20683402]|[https://pubmed.ncbi.nlm.nih.gov/17062733 17062733]|[https://pubmed.ncbi.nlm.nih.gov/23570331 23570331]|[https://pubmed.ncbi.nlm.nih.gov/30310530 30310530]|[https://pubmed.ncbi.nlm.nih.gov/31545316 31545316]|[https://pubmed.ncbi.nlm.nih.gov/23509763 23509763]|[https://pubmed.ncbi.nlm.nih.gov/24364909 24364909]|[https://pubmed.ncbi.nlm.nih.gov/18273440 18273440]|[https://pubmed.ncbi.nlm.nih.gov/28985528 28985528]|[https://pubmed.ncbi.nlm.nih.gov/22266579 22266579] <br>
  '''definition''' :  <br>
  '''definition''' :  <br>
  '''term_xref''' : GlycoMotif:GGM.000071|GTC:G57710SU|CID:[https://pubmed.ncbi.nlm.nih.gov/91849719 91849719]|KEGG:G03211|CHEBI:148232|SugarBind_Ligand:17 <br>
  '''term_xref''' : GTC:G84263XI|GlycoEpitope:EP0044|CID:[https://pubmed.ncbi.nlm.nih.gov/91845478 91845478]|CHEBI:154843 <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' : a marker for highly metastatic cells in rat mammary adenocarcinomas[PMID:[https://pubmed.ncbi.nlm.nih.gov/8504431 8504431]] <br>
  '''function''' : <br>
  '''disease_associations''' : Actinomycosis[SugarBind_Ligand:17] <br>
  '''disease_associations''' : teratocarcinoma[GlycoEpitope:EP0044] <br>
'''wikipedia''' : https://en.wikipedia.org/wiki/Ii_antigen_system <br>
'''essentials_of_glycobiology''' :  <br>
 
 
===GSD000114===
'''term (main_entry)''' : Keratan sulfate <br>
'''glycan_dictionary_accession''' : GSD000114 <br>
'''glytoucan_accession ''' :  [https://www.glygen.org/glycan/G82109MW G82109MW] <br>
'''term_in_sentence''' : Compared to the other classes of glycosaminoglycans (GAGs), that is, chondroitin/dermatan sulfate, heparin/heparan sulfate and hyaluronan, keratan sulfate (KS), have the least known of its interactive properties.[PMID: [https://pubmed.ncbi.nlm.nih.gov/30578672 30578672]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/29340594 29340594]|[https://pubmed.ncbi.nlm.nih.gov/30578672 30578672]|[https://pubmed.ncbi.nlm.nih.gov/12512857 12512857]|[https://pubmed.ncbi.nlm.nih.gov/29625490 29625490]|[https://pubmed.ncbi.nlm.nih.gov/25325967 25325967]|[https://pubmed.ncbi.nlm.nih.gov/30025865 30025865]|[https://pubmed.ncbi.nlm.nih.gov/29924315 29924315]|[https://pubmed.ncbi.nlm.nih.gov/9549787 9549787]|[https://pubmed.ncbi.nlm.nih.gov/11030741 11030741]|[https://pubmed.ncbi.nlm.nih.gov/28078490 28078490]|[https://pubmed.ncbi.nlm.nih.gov/8298243 8298243]|[https://pubmed.ncbi.nlm.nih.gov/29096187 29096187]|[https://pubmed.ncbi.nlm.nih.gov/30059256 30059256]|[https://pubmed.ncbi.nlm.nih.gov/26958998 26958998]|[https://pubmed.ncbi.nlm.nih.gov/26773479 26773479]|[https://pubmed.ncbi.nlm.nih.gov/22840010 22840010]|[https://pubmed.ncbi.nlm.nih.gov/15597951 15597951]|[https://pubmed.ncbi.nlm.nih.gov/28110685 28110685]|[https://pubmed.ncbi.nlm.nih.gov/28535934 28535934]|[https://pubmed.ncbi.nlm.nih.gov/2942429 2942429]|[https://pubmed.ncbi.nlm.nih.gov/18234072 18234072]|[https://pubmed.ncbi.nlm.nih.gov/8641829 8641829]|[https://pubmed.ncbi.nlm.nih.gov/8940154 8940154]|[https://pubmed.ncbi.nlm.nih.gov/2027120 2027120]|[https://pubmed.ncbi.nlm.nih.gov/30849116 30849116]|41589|[https://pubmed.ncbi.nlm.nih.gov/6238957 6238957]|[https://pubmed.ncbi.nlm.nih.gov/1907283 1907283]|[https://pubmed.ncbi.nlm.nih.gov/7722002 7722002]|[https://pubmed.ncbi.nlm.nih.gov/29275050 29275050]|[https://pubmed.ncbi.nlm.nih.gov/24274541 24274541]|[https://pubmed.ncbi.nlm.nih.gov/2527236 2527236]|[https://pubmed.ncbi.nlm.nih.gov/1731862 1731862]|[https://pubmed.ncbi.nlm.nih.gov/8991509 8991509]|[https://pubmed.ncbi.nlm.nih.gov/24291704 24291704]|[https://pubmed.ncbi.nlm.nih.gov/10517185 10517185]|[https://pubmed.ncbi.nlm.nih.gov/6451953 6451953]|[https://pubmed.ncbi.nlm.nih.gov/7688312 7688312]|[https://pubmed.ncbi.nlm.nih.gov/8663590 8663590]|139406|[https://pubmed.ncbi.nlm.nih.gov/25770829 25770829]|[https://pubmed.ncbi.nlm.nih.gov/25036480 25036480]|[https://pubmed.ncbi.nlm.nih.gov/9275006 9275006]|[https://pubmed.ncbi.nlm.nih.gov/25179279 25179279]|[https://pubmed.ncbi.nlm.nih.gov/32627425 32627425]|[https://pubmed.ncbi.nlm.nih.gov/26903438 26903438]|[https://pubmed.ncbi.nlm.nih.gov/27941632 27941632]|[https://pubmed.ncbi.nlm.nih.gov/12807022 12807022]|[https://pubmed.ncbi.nlm.nih.gov/32266652 32266652]|[https://pubmed.ncbi.nlm.nih.gov/21624346 21624346] <br>
'''definition''' : A sulfated glycosaminoglycan, a linear polymer that consists of the repeating disaccharide [3)-β-Gal-(1→4)-β-GlcNAc-(1→] and containing sulfo groups located at random positions.[CHEBI:60924] <br>
'''term_xref''' : CHEBI:60924|CID:446715|GlycoEpitope: EP0085|GTC: G82109MW  <br>
'''synonyms''' : keratan| Kerato sulphate|Kerato sulfate|Keratan sulphate|kerato 6'-sulfate|keratan 6'-sulfate|Kerato 6'-sulphate|Keratan 6'-sulphate <br>
'''function''' : Tissue hydration.[PMID: [https://pubmed.ncbi.nlm.nih.gov/11030741 11030741]] <br>
'''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453023/ Chapter 47]<br>




===GSD000115===
===GSD000162===
  '''term (main_entry)''' : LacdiNac <br>
  '''term (main_entry)''' : Sulfatide <br>
  '''glycan_dictionary_accession''' : GSD000115 <br>
  '''glycan_dictionary_accession''' : GSD000162 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G31736BK G31736BK] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G72548RZ G72548RZ] <br>
  '''term_in_sentence''' : We previously showed that the expression level of the LacdiNAc group in N-glycans decreases dramatically during the progression of human breast cancer.[PMID:[https://pubmed.ncbi.nlm.nih.gov/25003135 25003135]] <br>
  '''term_in_sentence''' : In a previous study we found that sulfatide was efficient in lowering HIV-1 viral loads in SCID mice engrafted with human fetal liver/thymus tissues (SCID-hu).[PMID:[https://pubmed.ncbi.nlm.nih.gov/23550344 23550344]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/25003135 25003135]|[https://pubmed.ncbi.nlm.nih.gov/31711843 31711843]|[https://pubmed.ncbi.nlm.nih.gov/31145522 31145522]|[https://pubmed.ncbi.nlm.nih.gov/27601469 27601469]|[https://pubmed.ncbi.nlm.nih.gov/30669833 30669833]|[https://pubmed.ncbi.nlm.nih.gov/25210040 25210040]|[https://pubmed.ncbi.nlm.nih.gov/24633693 24633693]|[https://pubmed.ncbi.nlm.nih.gov/24755437 24755437]|[https://pubmed.ncbi.nlm.nih.gov/22653491 22653491]|[https://pubmed.ncbi.nlm.nih.gov/30898876 30898876]|[https://pubmed.ncbi.nlm.nih.gov/7758724 7758724]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22474328 22474328] [https://pubmed.ncbi.nlm.nih.gov/22474328 22474328]]|[https://pubmed.ncbi.nlm.nih.gov/21305673 21305673]|[https://pubmed.ncbi.nlm.nih.gov/31558607 31558607]|[https://pubmed.ncbi.nlm.nih.gov/31271862 31271862]|[https://pubmed.ncbi.nlm.nih.gov/28549117 28549117]|[https://pubmed.ncbi.nlm.nih.gov/26213980 26213980]|[https://pubmed.ncbi.nlm.nih.gov/9134425 9134425]|[https://pubmed.ncbi.nlm.nih.gov/25561735 25561735]|[https://pubmed.ncbi.nlm.nih.gov/31756927 31756927]|[https://pubmed.ncbi.nlm.nih.gov/31170332 31170332]|[https://pubmed.ncbi.nlm.nih.gov/16282603 16282603]|[https://pubmed.ncbi.nlm.nih.gov/15265923 15265923]|[https://pubmed.ncbi.nlm.nih.gov/32267274 32267274]|[https://pubmed.ncbi.nlm.nih.gov/23015818 23015818]|[https://pubmed.ncbi.nlm.nih.gov/32676595 32676595]|[https://pubmed.ncbi.nlm.nih.gov/16728562 16728562]|[https://pubmed.ncbi.nlm.nih.gov/10814702 10814702]|[https://pubmed.ncbi.nlm.nih.gov/9591048 9591048]|[https://pubmed.ncbi.nlm.nih.gov/22245701 22245701]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29751628 29751628] [https://pubmed.ncbi.nlm.nih.gov/29751628 29751628]]|[https://pubmed.ncbi.nlm.nih.gov/22997242 22997242]|[https://pubmed.ncbi.nlm.nih.gov/15535969 15535969]|[https://pubmed.ncbi.nlm.nih.gov/31911241 31911241]|[https://pubmed.ncbi.nlm.nih.gov/30622255 30622255]|[https://pubmed.ncbi.nlm.nih.gov/29888905 29888905]|[https://pubmed.ncbi.nlm.nih.gov/30236114 30236114]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30298790 30298790] [https://pubmed.ncbi.nlm.nih.gov/30298790 30298790]]|[https://pubmed.ncbi.nlm.nih.gov/29373511 29373511]|[https://pubmed.ncbi.nlm.nih.gov/22298779 22298779]|[https://pubmed.ncbi.nlm.nih.gov/19179461 19179461]|[https://pubmed.ncbi.nlm.nih.gov/31606752 31606752]|[https://pubmed.ncbi.nlm.nih.gov/15653684 15653684]|[https://pubmed.ncbi.nlm.nih.gov/16403022 16403022]|[https://pubmed.ncbi.nlm.nih.gov/11162373 11162373]|[https://pubmed.ncbi.nlm.nih.gov/32005658 32005658]|[https://pubmed.ncbi.nlm.nih.gov/30529570 30529570] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/23550344 23550344]|[https://pubmed.ncbi.nlm.nih.gov/18465098 18465098]|[https://pubmed.ncbi.nlm.nih.gov/26542149 26542149]|[https://pubmed.ncbi.nlm.nih.gov/15158666 15158666]|[https://pubmed.ncbi.nlm.nih.gov/10434709 10434709]|[https://pubmed.ncbi.nlm.nih.gov/22619219 22619219]|[https://pubmed.ncbi.nlm.nih.gov/29676479 29676479]|[https://pubmed.ncbi.nlm.nih.gov/30196830 30196830]|[https://pubmed.ncbi.nlm.nih.gov/16143863 16143863]|[https://pubmed.ncbi.nlm.nih.gov/1052451 1052451]|[https://pubmed.ncbi.nlm.nih.gov/30400820 30400820]|[https://pubmed.ncbi.nlm.nih.gov/29887538 29887538]|[https://pubmed.ncbi.nlm.nih.gov/26981544 26981544]|[https://pubmed.ncbi.nlm.nih.gov/17986152 17986152]|[https://pubmed.ncbi.nlm.nih.gov/31739035 31739035]|[https://pubmed.ncbi.nlm.nih.gov/19941861 19941861]|[https://pubmed.ncbi.nlm.nih.gov/24578319 24578319]|[https://pubmed.ncbi.nlm.nih.gov/30531843 30531843]|[https://pubmed.ncbi.nlm.nih.gov/25645724 25645724]|[https://pubmed.ncbi.nlm.nih.gov/31197846 31197846]|[https://pubmed.ncbi.nlm.nih.gov/22821828 22821828]|[https://pubmed.ncbi.nlm.nih.gov/27861899 27861899]|[https://pubmed.ncbi.nlm.nih.gov/31037952 31037952]|[https://pubmed.ncbi.nlm.nih.gov/23593400 23593400]|[https://pubmed.ncbi.nlm.nih.gov/23604989 23604989]|[https://pubmed.ncbi.nlm.nih.gov/17855742 17855742]|[https://pubmed.ncbi.nlm.nih.gov/25966258 25966258]|[https://pubmed.ncbi.nlm.nih.gov/25989600 25989600]|[https://pubmed.ncbi.nlm.nih.gov/9657940 9657940]|[https://pubmed.ncbi.nlm.nih.gov/29497057 29497057]|[https://pubmed.ncbi.nlm.nih.gov/12838515 12838515]|[https://pubmed.ncbi.nlm.nih.gov/25170267 25170267]|[https://pubmed.ncbi.nlm.nih.gov/9878314 9878314]|[https://pubmed.ncbi.nlm.nih.gov/20554435 20554435]|[https://pubmed.ncbi.nlm.nih.gov/1410493 1410493]|[https://pubmed.ncbi.nlm.nih.gov/26585924 26585924]|[https://pubmed.ncbi.nlm.nih.gov/17257892 17257892]|[https://pubmed.ncbi.nlm.nih.gov/17044925 17044925]|[https://pubmed.ncbi.nlm.nih.gov/21089387 21089387]|[https://pubmed.ncbi.nlm.nih.gov/11445552 11445552]|[https://pubmed.ncbi.nlm.nih.gov/22977233 22977233]|[https://pubmed.ncbi.nlm.nih.gov/21437360 21437360]|[https://pubmed.ncbi.nlm.nih.gov/17179664 17179664]|[https://pubmed.ncbi.nlm.nih.gov/6273571 6273571]|[https://pubmed.ncbi.nlm.nih.gov/8370675 8370675] <br>
  '''definition''' : An amino disaccharide consisting of N-acetylglucosamine having an N-acetylgalactosaminyl resiude attached at the 4-position via a β-linkage.[CHEBI:61190] <br>
  '''definition''' : <br>
  '''term_xref''' : GTC:G31736BK|GlycoEpitope:P0150|CID:[https://pubmed.ncbi.nlm.nih.gov/25257164 25257164]|CHEBI:61190|GlycoMotif:GGM.000016 <br>
  '''term_xref''' : GlycoMotif:GGM.000063|GTC:G72548RZ  <br>
  '''synonyms''' : LDN <br>
  '''synonyms''' : <br>
  '''function''' : Has a role of epitope.[CHEBI:61190] <br>
  '''function''' : <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453023/ Chapter 47] <br>




===GSD000116===
===GSD000163===
  '''term (main_entry)''' : Lactosylceramide <br>
  '''term (main_entry)''' : T antigen <br>
  '''glycan_dictionary_accession''' : GSD000116 <br>
  '''glycan_dictionary_accession''' : GSD000163 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G84224TW G84224TW] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G00031MO G00031MO] <br>
  '''term_in_sentence''' : In the 1970s, a neutral glycosphingolipid lactosylceramide (LacCer) was found to bind specifically to several kinds of microorganisms.[PMID:[https://pubmed.ncbi.nlm.nih.gov/30175814 30175814]] <br>
  '''term_in_sentence''' : Tn, sTn, and T antigen neo- or over-expression occurs in many types of cancer including gastric, colon, breast, lung, esophageal, prostate, and endometrial cancer.[PMID:27679419] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/30175814 30175814]|[https://pubmed.ncbi.nlm.nih.gov/26900161 26900161]|[https://pubmed.ncbi.nlm.nih.gov/30502090 30502090]|[https://pubmed.ncbi.nlm.nih.gov/29624959 29624959]|[https://pubmed.ncbi.nlm.nih.gov/28444900 28444900]|[https://pubmed.ncbi.nlm.nih.gov/25408340 25408340]|[https://pubmed.ncbi.nlm.nih.gov/31801289 31801289]|[https://pubmed.ncbi.nlm.nih.gov/29099167 29099167]|[https://pubmed.ncbi.nlm.nih.gov/25595946 25595946]|[https://pubmed.ncbi.nlm.nih.gov/32592089 32592089]|[https://pubmed.ncbi.nlm.nih.gov/27729551 27729551]|[https://pubmed.ncbi.nlm.nih.gov/24658420 24658420]|[https://pubmed.ncbi.nlm.nih.gov/25216636 25216636]|[https://pubmed.ncbi.nlm.nih.gov/25638276 25638276]|[https://pubmed.ncbi.nlm.nih.gov/9499377 9499377]|[https://pubmed.ncbi.nlm.nih.gov/17986153 17986153]|[https://pubmed.ncbi.nlm.nih.gov/8143857 8143857]|[https://pubmed.ncbi.nlm.nih.gov/23801329 23801329]|[https://pubmed.ncbi.nlm.nih.gov/18077097 18077097]|[https://pubmed.ncbi.nlm.nih.gov/32708181 32708181]|[https://pubmed.ncbi.nlm.nih.gov/15346887 15346887]|[https://pubmed.ncbi.nlm.nih.gov/19015977 19015977]|[https://pubmed.ncbi.nlm.nih.gov/18393821 18393821]|[https://pubmed.ncbi.nlm.nih.gov/25279740 25279740]|[https://pubmed.ncbi.nlm.nih.gov/21057870 21057870]|[https://pubmed.ncbi.nlm.nih.gov/11915327 11915327]|[https://pubmed.ncbi.nlm.nih.gov/25212460 25212460]|[https://pubmed.ncbi.nlm.nih.gov/23882130 23882130]|[https://pubmed.ncbi.nlm.nih.gov/11915329 11915329]|[https://pubmed.ncbi.nlm.nih.gov/8195125 8195125]|[https://pubmed.ncbi.nlm.nih.gov/8808768 8808768]|[https://pubmed.ncbi.nlm.nih.gov/3396945 3396945]|[https://pubmed.ncbi.nlm.nih.gov/22128256 22128256]|[https://pubmed.ncbi.nlm.nih.gov/6733104 6733104]|[https://pubmed.ncbi.nlm.nih.gov/24968752 24968752]|[https://pubmed.ncbi.nlm.nih.gov/32518749 32518749]|[https://pubmed.ncbi.nlm.nih.gov/30688114 30688114]|[https://pubmed.ncbi.nlm.nih.gov/7666005 7666005]|[https://pubmed.ncbi.nlm.nih.gov/8200356 8200356]|[https://pubmed.ncbi.nlm.nih.gov/24718572 24718572]|[https://pubmed.ncbi.nlm.nih.gov/6193809 6193809]|[https://pubmed.ncbi.nlm.nih.gov/25781947 25781947]|[https://pubmed.ncbi.nlm.nih.gov/12383912 12383912]|[https://pubmed.ncbi.nlm.nih.gov/26086247 26086247]|[https://pubmed.ncbi.nlm.nih.gov/30606995 30606995]|[https://pubmed.ncbi.nlm.nih.gov/12419803 12419803] <br>
'''publication''' : 723127|[https://pubmed.ncbi.nlm.nih.gov/19505650 19505650]|[https://pubmed.ncbi.nlm.nih.gov/31527246 31527246]|[https://pubmed.ncbi.nlm.nih.gov/28113048 28113048]|[https://pubmed.ncbi.nlm.nih.gov/25868857 25868857]|[https://pubmed.ncbi.nlm.nih.gov/26731525 26731525]|[https://pubmed.ncbi.nlm.nih.gov/22994493 22994493]|[https://pubmed.ncbi.nlm.nih.gov/3849428 3849428]|[https://pubmed.ncbi.nlm.nih.gov/25589241 25589241]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12709866 12709866] [https://pubmed.ncbi.nlm.nih.gov/12709866 12709866]]|[https://pubmed.ncbi.nlm.nih.gov/26615524 26615524]|[https://pubmed.ncbi.nlm.nih.gov/26136575 26136575]|[https://pubmed.ncbi.nlm.nih.gov/19671663 19671663]|[https://pubmed.ncbi.nlm.nih.gov/18551603 18551603]|[https://pubmed.ncbi.nlm.nih.gov/11160729 11160729]|[https://pubmed.ncbi.nlm.nih.gov/22261839 22261839]|[https://pubmed.ncbi.nlm.nih.gov/30758913 30758913]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25681708 25681708] [https://pubmed.ncbi.nlm.nih.gov/25681708 25681708]]|[https://pubmed.ncbi.nlm.nih.gov/29113555 29113555]|[https://pubmed.ncbi.nlm.nih.gov/24998850 24998850]|[https://pubmed.ncbi.nlm.nih.gov/1654819 1654819]|[https://pubmed.ncbi.nlm.nih.gov/28039910 28039910]|[https://pubmed.ncbi.nlm.nih.gov/29206210 29206210]|[https://pubmed.ncbi.nlm.nih.gov/32404521 32404521]|[https://pubmed.ncbi.nlm.nih.gov/10555041 10555041]|[https://pubmed.ncbi.nlm.nih.gov/26517398 26517398]|[https://pubmed.ncbi.nlm.nih.gov/2446015 2446015]|[https://pubmed.ncbi.nlm.nih.gov/2998768 2998768]|[https://pubmed.ncbi.nlm.nih.gov/3026642 3026642]|[https://pubmed.ncbi.nlm.nih.gov/18812503 18812503]|[https://pubmed.ncbi.nlm.nih.gov/6092664 6092664]|[https://pubmed.ncbi.nlm.nih.gov/2153691 2153691]|[https://pubmed.ncbi.nlm.nih.gov/8709258 8709258]|[https://pubmed.ncbi.nlm.nih.gov/3009889 3009889]|[https://pubmed.ncbi.nlm.nih.gov/15109748 15109748]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12709866 12709866] [https://pubmed.ncbi.nlm.nih.gov/12709866 12709866]]|[https://pubmed.ncbi.nlm.nih.gov/31787742 31787742]|[https://pubmed.ncbi.nlm.nih.gov/27433780 27433780]|[https://pubmed.ncbi.nlm.nih.gov/26017382 26017382]|[https://pubmed.ncbi.nlm.nih.gov/24048785 24048785]|[https://pubmed.ncbi.nlm.nih.gov/26735515 26735515]|[https://pubmed.ncbi.nlm.nih.gov/9224657 9224657]|[https://pubmed.ncbi.nlm.nih.gov/26061652 26061652]|[https://pubmed.ncbi.nlm.nih.gov/29343574 29343574]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25681708 25681708] [https://pubmed.ncbi.nlm.nih.gov/25681708 25681708]]|[https://pubmed.ncbi.nlm.nih.gov/23805194 23805194]|[https://pubmed.ncbi.nlm.nih.gov/26751495 26751495]|[https://pubmed.ncbi.nlm.nih.gov/22023388 22023388]|[https://pubmed.ncbi.nlm.nih.gov/15381338 15381338]|[https://pubmed.ncbi.nlm.nih.gov/8249277 8249277]|[https://pubmed.ncbi.nlm.nih.gov/3023660 3023660]|[https://pubmed.ncbi.nlm.nih.gov/25866902 25866902] <br>
  '''definition''' : Glycosphingolipids which contain as their polar head group a lactose moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in lactosylceramide beta-galactosidase, is the cause of lactosylceramidosis.[MeSH:D007790] <br>
  '''definition''' : An amino disaccharide composed of D-galactose and N-acetyl-α-D-galactosaminyl residues in β-(1→3) linkage.[CHEBI:61820] <br>
  '''term_xref''' : GTC:G84224TW|MeSH:D007790|GlycoMotif:GGM.000064|GlycoEpitope:EP0078|SugarBind_Ligand:3 <br>
  '''term_xref''' : GTC:G00031MO|GlycoEpitope:EP0020|CID:[https://pubmed.ncbi.nlm.nih.gov/5288347 5288347]|CHEBI:61820|GlycoMotif:GGM.000009 <br>
  '''synonyms''' : LacCer|Lc2|CDH <br>
  '''synonyms''' : TF antigen <br>
  '''function''' : mammalian cell receptors for Neisseria gonorrhoeae recognized by Helicobacter pylori[GlycoEpitope:EP0078] <br>
  '''function''' : accumulation Lipoprotein(a) or LDL within arterial walls in atherogenesis [GlycoEpitope:EP0020]|cancer progression (increase interaction/communication of the cells)[GlycoEpitope:EP0020]|T antigen expression in RMA lymphoma cells leads to a reduced growth of the tumor[GlycoEpitope:EP0020]|correlation with elevated Golgi pH in cancer cell (breast, colorectal cancer cells)[GlycoEpitope:EP0020]|T antigen on apical surfaces of corneal epithelial cells provide protection against rose bengal penetrance.[GlycoEpitope:EP0020]|reduction of a flexibility of the glycosidic bond and thereby favour certain glycan conformation[GlycoEpitope:EP0020]|T antigen is a target for NK cell-mediated lysis[GlycoEpitope:EP0020]|inverse relationship between T antigen expression and VWF plasma levels[GlycoEpitope:EP0020] <br>
'''disease_associations''' : chronic gastritis[GlycoEpitope:EP0078,SugarBind_Ligand:3]|duodenal ulcers[GlycoEpitope:EP0078]|gastric adenocarcinoma[GlycoEpitope:EP0078,SugarBind_Ligand:3]|gastric ulcers[GlycoEpitope:EP0078]|Pleuropneumonia[SugarBind_Ligand:3]|Porcine fibrinohemorrhagic necrotizing pleuropneumonia[SugarBind_Ligand:3]|Actinomycosis[SugarBind_Ligand:3]|Pertussis[SugarBind_Ligand:3]|Candidiasis[SugarBind_Ligand:3]|Cryptococcosis[SugarBind_Ligand:3]|Hemorrhagic colitis[SugarBind_Ligand:3]|Peptic ulcers[SugarBind_Ligand:3]|Histoplasmosis[SugarBind_Ligand:3]|Pharyngitis[SugarBind_Ligand:3]|Tracheobronchitis[SugarBind_Ligand:3]|Gonorrhea[SugarBind_Ligand:3]|Sporotrichosis[SugarBind_Ligand:3]|Plague[SugarBind_Ligand:3]|Diarrhea[SugarBind_Ligand:3] <br>
'''disease_associations''' : anaplastic meningioma[GlycoEpitope:EP0020]|breast cancer[GlycoEpitope:EP0020]|colorectal cancer[GlycoEpitope:EP0020]|colon cancer[GlycoEpitope:EP0020]|esophageal cancer|gastric cancer[GlycoEpitope:EP0020]|liver cancer[GlycoEpitope:EP0020]|ovarian cancer[GlycoEpitope:EP0020]|prostate cancer[GlycoEpitope:EP0020]|bladder tumor[GlycoEpitope:EP0020]|invasive pneumococcal infection (hemolytic uremic syndrome, hemolytic anemia)[GlycoEpitope:EP0020] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453033/ Chapter 17]<br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453023/ Chapter 47]<br>




===GSD000117===
===GSD000164===
'''term (main_entry)''' : Lactotriaosylceramide <br>
'''term (main_entry)''' : Tetraantennary <br>
'''glycan_dictionary_accession''' : GSD000117 <br>
'''glycan_dictionary_accession''' : GSD000164 <br>
'''glytoucan_accession ''' : [https://www.glygen.org/glycan/G06239NA G06239NA] <br>
'''glytoucan_accession ''' : <br>
'''term_in_sentence''' : The results showed that AML patients had higher expression of the GSL lactotriaosylceramide (Lc3), GM3 and neolactotetraosylceramide (nLc4) in their bone marrow than did the healthy donors (P < 0.05), especially the M1 subtype of AML.[PMID:[https://pubmed.ncbi.nlm.nih.gov/22411838 22411838]] <br>
'''term_in_sentence''' : In contrast, myeloma IgE showed a higher abundance of triantennary and tetraantennary glycan structures and a low abundance of species with a bisecting N-acetylglucosamine.[PMID:[https://pubmed.ncbi.nlm.nih.gov/24308486 24308486]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/22411838 22411838]|[https://pubmed.ncbi.nlm.nih.gov/20693232 20693232]|[https://pubmed.ncbi.nlm.nih.gov/26104834 26104834]|[https://pubmed.ncbi.nlm.nih.gov/27435676 27435676]|[https://pubmed.ncbi.nlm.nih.gov/26405105 26405105]|[https://pubmed.ncbi.nlm.nih.gov/32340400 32340400]|[https://pubmed.ncbi.nlm.nih.gov/25241919 25241919]|[https://pubmed.ncbi.nlm.nih.gov/23404501 23404501]|[https://pubmed.ncbi.nlm.nih.gov/32452379 32452379]|[https://pubmed.ncbi.nlm.nih.gov/2960671 2960671]|272643|[https://pubmed.ncbi.nlm.nih.gov/27711049 27711049]|[https://pubmed.ncbi.nlm.nih.gov/33202844 33202844]|[https://pubmed.ncbi.nlm.nih.gov/4060695 4060695]|[https://pubmed.ncbi.nlm.nih.gov/27638607 27638607]|[https://pubmed.ncbi.nlm.nih.gov/20547865 20547865]|[https://pubmed.ncbi.nlm.nih.gov/2277039 2277039]|[https://pubmed.ncbi.nlm.nih.gov/6238026 6238026]|[https://pubmed.ncbi.nlm.nih.gov/8448388 8448388]|[https://pubmed.ncbi.nlm.nih.gov/8489255 8489255]|[https://pubmed.ncbi.nlm.nih.gov/9363437 9363437]|[https://pubmed.ncbi.nlm.nih.gov/11836161 11836161]|[https://pubmed.ncbi.nlm.nih.gov/6892925 6892925]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1551117 1551117] [https://pubmed.ncbi.nlm.nih.gov/1551117 1551117]]|[https://pubmed.ncbi.nlm.nih.gov/6811267 6811267]|[https://pubmed.ncbi.nlm.nih.gov/8059935 8059935]|[https://pubmed.ncbi.nlm.nih.gov/7861954 7861954]|[https://pubmed.ncbi.nlm.nih.gov/11283017 11283017]|[https://pubmed.ncbi.nlm.nih.gov/8514762 8514762]|[https://pubmed.ncbi.nlm.nih.gov/1291049 1291049]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3805024 3805024] [https://pubmed.ncbi.nlm.nih.gov/3805024 3805024]]|[https://pubmed.ncbi.nlm.nih.gov/10816509 10816509]|[https://pubmed.ncbi.nlm.nih.gov/12393713 12393713]|[https://pubmed.ncbi.nlm.nih.gov/6417117 6417117]|[https://pubmed.ncbi.nlm.nih.gov/11054095 11054095]|[https://pubmed.ncbi.nlm.nih.gov/8781973 8781973]|[https://pubmed.ncbi.nlm.nih.gov/1692829 1692829] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/24308486 24308486]|[https://pubmed.ncbi.nlm.nih.gov/17951374 17951374]|[https://pubmed.ncbi.nlm.nih.gov/28880909 28880909]|[https://pubmed.ncbi.nlm.nih.gov/9177699 9177699]|[https://pubmed.ncbi.nlm.nih.gov/9760189 9760189]|[https://pubmed.ncbi.nlm.nih.gov/12322961 12322961]|[https://pubmed.ncbi.nlm.nih.gov/20129637 20129637]|[https://pubmed.ncbi.nlm.nih.gov/2492275 2492275]|[https://pubmed.ncbi.nlm.nih.gov/3402460 3402460]|[https://pubmed.ncbi.nlm.nih.gov/2361735 2361735]|[https://pubmed.ncbi.nlm.nih.gov/6525453 6525453]|[https://pubmed.ncbi.nlm.nih.gov/27730440 27730440]|[https://pubmed.ncbi.nlm.nih.gov/2551687 2551687]|[https://pubmed.ncbi.nlm.nih.gov/25365149 25365149]|[https://pubmed.ncbi.nlm.nih.gov/9751793 9751793]|[https://pubmed.ncbi.nlm.nih.gov/29875690 29875690]|[https://pubmed.ncbi.nlm.nih.gov/29479898 29479898]|[https://pubmed.ncbi.nlm.nih.gov/9134426 9134426]|[https://pubmed.ncbi.nlm.nih.gov/30943309 30943309]|[https://pubmed.ncbi.nlm.nih.gov/3546284 3546284]|[https://pubmed.ncbi.nlm.nih.gov/29888905 29888905]|[https://pubmed.ncbi.nlm.nih.gov/30624066 30624066]|[https://pubmed.ncbi.nlm.nih.gov/30537828 30537828]|[https://pubmed.ncbi.nlm.nih.gov/31110965 31110965]|[https://pubmed.ncbi.nlm.nih.gov/29311294 29311294]|[https://pubmed.ncbi.nlm.nih.gov/12852965 12852965]|[https://pubmed.ncbi.nlm.nih.gov/3015940 3015940]|[https://pubmed.ncbi.nlm.nih.gov/1907570 1907570]|[https://pubmed.ncbi.nlm.nih.gov/29137999 29137999]|[https://pubmed.ncbi.nlm.nih.gov/29359131 29359131]|[https://pubmed.ncbi.nlm.nih.gov/29858715 29858715]|[https://pubmed.ncbi.nlm.nih.gov/30295034 30295034]|[https://pubmed.ncbi.nlm.nih.gov/31829566 31829566]|[https://pubmed.ncbi.nlm.nih.gov/8381405 8381405]|[https://pubmed.ncbi.nlm.nih.gov/26929217 26929217]|[https://pubmed.ncbi.nlm.nih.gov/20662591 20662591]|[https://pubmed.ncbi.nlm.nih.gov/30612270 30612270]|[https://pubmed.ncbi.nlm.nih.gov/3089784 3089784]|[https://pubmed.ncbi.nlm.nih.gov/28186213 28186213]|[https://pubmed.ncbi.nlm.nih.gov/3427034 3427034]|[https://pubmed.ncbi.nlm.nih.gov/26763099 26763099]|[https://pubmed.ncbi.nlm.nih.gov/27354006 27354006]|[https://pubmed.ncbi.nlm.nih.gov/24991291 24991291]|[https://pubmed.ncbi.nlm.nih.gov/7496138 7496138]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1940447 1940447] [https://pubmed.ncbi.nlm.nih.gov/1940447 1940447]]|[https://pubmed.ncbi.nlm.nih.gov/11114588 11114588]|[https://pubmed.ncbi.nlm.nih.gov/29031301 29031301]|[https://pubmed.ncbi.nlm.nih.gov/9448855 9448855]|[https://pubmed.ncbi.nlm.nih.gov/3979385 3979385]|[https://pubmed.ncbi.nlm.nih.gov/27722599 27722599]|[https://pubmed.ncbi.nlm.nih.gov/31126011 31126011]|[https://pubmed.ncbi.nlm.nih.gov/28002670 28002670]|[https://pubmed.ncbi.nlm.nih.gov/28991403 28991403]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24032650 24032650] [https://pubmed.ncbi.nlm.nih.gov/24032650 24032650]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15316281 15316281] [https://pubmed.ncbi.nlm.nih.gov/15316281 15316281]]|[https://pubmed.ncbi.nlm.nih.gov/25154914 25154914]|[https://pubmed.ncbi.nlm.nih.gov/22490318 22490318]|[https://pubmed.ncbi.nlm.nih.gov/22430811 22430811]|[https://pubmed.ncbi.nlm.nih.gov/1463783 1463783]|[https://pubmed.ncbi.nlm.nih.gov/18803208 18803208]|[https://pubmed.ncbi.nlm.nih.gov/7881173 7881173]|[https://pubmed.ncbi.nlm.nih.gov/7697655 7697655]|[https://pubmed.ncbi.nlm.nih.gov/7240157 7240157]|[https://pubmed.ncbi.nlm.nih.gov/1768292 1768292] <br>
'''definition''' : A linear amino trisaccharide consisting of β-D-glucose at the reducing end having an N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl group attached at the 4-position.[CHEBI:61758] <br>
'''definition''' : Type of N-linked glycan in which four antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The four antennae are initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 2 GlcNAcs to the _6 Man (at the 2 and 6 positions) of the trimannosyl core. Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues.  [Essentials of Glycobiology:[https://www.ncbi.nlm.nih.gov/books/NBK453019/ Glossary]] <br>
'''term_xref''' : GTC:G06239NA|GlycoMotif:GGM.000067|MeSH:C025575|CID:[https://pubmed.ncbi.nlm.nih.gov/10230777 10230777]|CHEBI:61758|SugarBind_Ligand:20<br>
'''term_xref''' : <br>
'''synonyms''' : Lc3|Lc(3)Cer|Lc_3 <br>
'''synonyms''' : <br>
'''function''' : acute myeloid leukemia-associated glycosphingolipids lactotriaosylceramide, GM3 and neolactotetraosylceramide are possibly involved in initiation and differentiation of acute myeloid leukemia.[PMID:[https://pubmed.ncbi.nlm.nih.gov/22411838 22411838]] <br>
'''function''' : <br>
  '''disease_associations''' : Pharyngitis[SugarBind_Ligand:20]|Tracheobronchitis[SugarBind_Ligand:20]|Gonorrhea[SugarBind_Ligand:20]|Actinomycosis[SugarBind_Ligand:20]|Diarrhea[SugarBind_Ligand:20] <br>
'''disease_associations''' :  <br>
'''wikipedia''' :  <br>
'''wikipedia''' : https://www.wikidata.org/wiki/Q[https://pubmed.ncbi.nlm.nih.gov/27104888 27104888] <br>
'''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
'''essentials_of_glycobiology''' :  <br>




===GSD000118===
===GSD000165===
  '''term (main_entry)''' : LcGg4 <br>
  '''term (main_entry)''' : Tetraantennary complex-type <br>
  '''glycan_dictionary_accession''' : GSD000118 <br>
  '''glycan_dictionary_accession''' : GSD000165 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G62554JH G62554JH] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : Murine leukemia cells (M1), in their undifferentiated state, have been characterized by the presence of cancer-associated lactoganglio-series glycolipids, one of which was identified as lactogangliotetraosylceramide (LcGg4) having a novel branching at the II-Gal of lactosylceramide through GlcNAc beta 1----3 and GalNAc beta 1----4 linkage, as shown below (Kannagi, R., Levery, S.B., and Hakomori, S. (1984) J. Biol. Chem., 259, 8444-8451): GalNAc beta 1----4 Gal beta 1----4Glc beta 1----1Cer GlcNac beta 1----3 [PMID: [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3805024 3805024] [https://pubmed.ncbi.nlm.nih.gov/3805024 3805024]]] <br>
  '''term_in_sentence''' : A variety of high-mannose structures , as well as bi-, tri-, and tetraantennary complex-type carbohydrate , has been found, in relative amounts of 1-25% of the total oligosaccharides.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1899031 1899031] [https://pubmed.ncbi.nlm.nih.gov/1899031 1899031]]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3805024 3805024] [https://pubmed.ncbi.nlm.nih.gov/3805024 3805024]]|[https://pubmed.ncbi.nlm.nih.gov/33395290 33395290] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1899031 1899031] [https://pubmed.ncbi.nlm.nih.gov/1899031 1899031]]|[https://pubmed.ncbi.nlm.nih.gov/8251489 8251489]|[https://pubmed.ncbi.nlm.nih.gov/8274017 8274017]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1899031 1899031] [https://pubmed.ncbi.nlm.nih.gov/1899031 1899031]]| [https://pubmed.ncbi.nlm.nih.gov/6317691 6317691]|[https://pubmed.ncbi.nlm.nih.gov/23668542 23668542]| [https://pubmed.ncbi.nlm.nih.gov/6088518 6088518]|[https://pubmed.ncbi.nlm.nih.gov/21495009 21495009]|[https://pubmed.ncbi.nlm.nih.gov/1457971 1457971]|[https://pubmed.ncbi.nlm.nih.gov/1783599 1783599]|[https://pubmed.ncbi.nlm.nih.gov/10988252 10988252]|[https://pubmed.ncbi.nlm.nih.gov/11425798 11425798]|[https://pubmed.ncbi.nlm.nih.gov/7522229 7522229]|[https://pubmed.ncbi.nlm.nih.gov/2574992 2574992]|[https://pubmed.ncbi.nlm.nih.gov/3730425 3730425]|[https://pubmed.ncbi.nlm.nih.gov/10200178 10200178]|[https://pubmed.ncbi.nlm.nih.gov/2939068 2939068]|[https://pubmed.ncbi.nlm.nih.gov/21584695 21584695]| [https://pubmed.ncbi.nlm.nih.gov/7524670 7524670]|[https://pubmed.ncbi.nlm.nih.gov/7682847 7682847]|[https://pubmed.ncbi.nlm.nih.gov/2930192 2930192]|[https://pubmed.ncbi.nlm.nih.gov/1726466 1726466]|[https://pubmed.ncbi.nlm.nih.gov/9881746 9881746]|[https://pubmed.ncbi.nlm.nih.gov/11068879 11068879]|[https://pubmed.ncbi.nlm.nih.gov/6704968 6704968]|[https://pubmed.ncbi.nlm.nih.gov/2302846 2302846]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24032650 24032650] [https://pubmed.ncbi.nlm.nih.gov/24032650 24032650]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15316281 15316281] [https://pubmed.ncbi.nlm.nih.gov/15316281 15316281]]|[https://pubmed.ncbi.nlm.nih.gov/11051207 11051207]|[https://pubmed.ncbi.nlm.nih.gov/10220588 10220588]|[https://pubmed.ncbi.nlm.nih.gov/2813359 2813359]|[https://pubmed.ncbi.nlm.nih.gov/2174368 2174368]|[https://pubmed.ncbi.nlm.nih.gov/21755550 21755550]|[https://pubmed.ncbi.nlm.nih.gov/3571208 3571208]|[https://pubmed.ncbi.nlm.nih.gov/1929437 1929437]|[https://pubmed.ncbi.nlm.nih.gov/3681300 3681300]|[https://pubmed.ncbi.nlm.nih.gov/6581225 6581225]|[https://pubmed.ncbi.nlm.nih.gov/3364983 3364983]|[https://pubmed.ncbi.nlm.nih.gov/2902877 2902877]|[https://pubmed.ncbi.nlm.nih.gov/2297756 2297756]|[https://pubmed.ncbi.nlm.nih.gov/1315684 1315684]|[https://pubmed.ncbi.nlm.nih.gov/6830758 6830758]|[https://pubmed.ncbi.nlm.nih.gov/1998670 1998670] <br>
  '''definition''' : N-[(2S,3R,4R,5R,6R)-2-[(2R,3S,4R,5R,6S)-4-[(2S,3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide is an oligosaccharide.[CHEBI:152521] <br>
  '''definition''' : Type of N-linked glycan in which four antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The four antennae are initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 2 GlcNAcs to the _6 Man (at the 2 and 6 positions) of the trimannosyl core. Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:[https://www.ncbi.nlm.nih.gov/books/NBK453019/ Glossary]] <br>
  '''term_xref''' : GlycoMotif:GGM.000075|GTC:G62554JH|CID:[https://pubmed.ncbi.nlm.nih.gov/91850076 91850076]|CHEBI:152521|GlycoEpitope:EP0035  <br>
  '''term_xref''' : https://www.sigmaaldrich.com/technical-documents/articles/biology/glycobiology/n-glycans.html <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453030/ Chapter 10]<br>




===GSD000119===
===GSD000166===
  '''term (main_entry)''' : Lewis a <br>
  '''term (main_entry)''' : Tetrasialylated diantennary <br>
  '''glycan_dictionary_accession''' : GSD000119 <br>
  '''glycan_dictionary_accession''' : GSD000166 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G00047MO G00047MO] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : Regardless of the vaccine administered, significantly fewer of the children with Lewis A phenotype (0/14) seroconverted after receiving the first vaccine dose compared to 26% (45/175) of those with the Lewis B phenotype and 32% (15/47) of the Lewis negative individuals (P < 0.01). [PMID:[https://pubmed.ncbi.nlm.nih.gov/29367698 29367698]] <br>
  '''term_in_sentence''' : A further preparation, obtained from the most anionic DEAE-cellulose fraction (peak V) or rTf contained several tetrasialylated diantennary glycans whose precise structures remain to be established in future studies.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1997323 1997323] [https://pubmed.ncbi.nlm.nih.gov/1997323 1997323]]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/29367698 29367698]|[https://pubmed.ncbi.nlm.nih.gov/27187324 27187324]|[https://pubmed.ncbi.nlm.nih.gov/30562693 30562693]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27646625 27646625] [https://pubmed.ncbi.nlm.nih.gov/27646625 27646625]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26911286 26911286] [https://pubmed.ncbi.nlm.nih.gov/26911286 26911286]]|[https://pubmed.ncbi.nlm.nih.gov/30225822 30225822]|[https://pubmed.ncbi.nlm.nih.gov/28600306 28600306]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32527016 32527016] [https://pubmed.ncbi.nlm.nih.gov/32527016 32527016]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2385097 2385097] [https://pubmed.ncbi.nlm.nih.gov/2385097 2385097]]|[https://pubmed.ncbi.nlm.nih.gov/11064310 11064310]|[https://pubmed.ncbi.nlm.nih.gov/23809433 23809433]|[https://pubmed.ncbi.nlm.nih.gov/30050155 30050155]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1615929 1615929] [https://pubmed.ncbi.nlm.nih.gov/1615929 1615929]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29527514 29527514] [https://pubmed.ncbi.nlm.nih.gov/29527514 29527514]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9207264 9207264] [https://pubmed.ncbi.nlm.nih.gov/9207264 9207264]]|[https://pubmed.ncbi.nlm.nih.gov/1675497 1675497]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3677023 3677023] [https://pubmed.ncbi.nlm.nih.gov/3677023 3677023]]|[https://pubmed.ncbi.nlm.nih.gov/27705835 27705835]|[https://pubmed.ncbi.nlm.nih.gov/7593252 7593252]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2579997 2579997] [https://pubmed.ncbi.nlm.nih.gov/2579997 2579997]]|[https://pubmed.ncbi.nlm.nih.gov/17630273 17630273]|[https://pubmed.ncbi.nlm.nih.gov/9350993 9350993]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9098001 9098001] [https://pubmed.ncbi.nlm.nih.gov/9098001 9098001]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1997323 1997323] [https://pubmed.ncbi.nlm.nih.gov/1997323 1997323]] <br>
  '''definition''' : A lewis blood group antigen with structure beta-D-Galp-(1->3)-[alpha-L-Fucp-(1->4)]-D-GlcpNAc consisting of N-acetylglucosamine having a fucosyl residue attached at the 4-position via an alpha-linkage and a galactosyl residue attached at the 3-position via a beta-linkage. It has a role as an epitope and an antigen. It is an amino trisaccharide and a glucosamine oligosaccharide.[CHEBI:62265] <br>
  '''definition''' : A biantennary glycan with two GlcNAc branches linked to the core and the addition of four sialic acid residues. <br>
  '''term_xref''' : GTC:G00047MO|CID:[https://pubmed.ncbi.nlm.nih.gov/22806751 22806751]|CHEBI:62265|GlycoMotif:GGM.000020|SugarBind_Ligand:155 <br>
  '''term_xref''' :  <br>
  '''synonyms''' : Le(a)|Lea-3|Lea|Le^a <br>
  '''synonyms''' : <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' : Gastroenteritis[SugarBind_Ligand:155] <br>
  '''disease_associations''' : <br>
  '''wikipedia''' : https://www.wikidata.org/wiki/Q[https://pubmed.ncbi.nlm.nih.gov/50687009 50687009] <br>
  '''wikipedia''' : <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000120===
===GSD000167===
[[File:G39211DH.png|thumb|G39211DH]]
  '''term (main_entry)''' : Tn antigen <br>
  '''term (main_entry)''' : Lewis b <br>
  '''glycan_dictionary_accession''' : GSD000167 <br>
  '''glycan_dictionary_accession''' : GSD000120 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G57321FI G57321FI] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G39211DH G39211DH] <br>
  '''term_in_sentence''' : Furthermore, we confirmed that LS174T cells (Tn-positive) transfected with wild-type Cosmc, thus expressing no Tn antigen, had down-regulation of H-Ras expression and subsequent inhibition of EMT process.[PMID:30637914] <br>
  '''term_in_sentence''' : Human mannose-binding lectin preferentially binds to human colon adenocarcinoma cell lines expressing high amount of Lewis A and Lewis B antigens.[PMID:[https://pubmed.ncbi.nlm.nih.gov/10328552 10328552]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/27679419 27679419]|[https://pubmed.ncbi.nlm.nih.gov/31938254 31938254]|[https://pubmed.ncbi.nlm.nih.gov/30637914 30637914]|[https://pubmed.ncbi.nlm.nih.gov/24643043 24643043]|[https://pubmed.ncbi.nlm.nih.gov/31225574 31225574]|[https://pubmed.ncbi.nlm.nih.gov/21259410 21259410]|[https://pubmed.ncbi.nlm.nih.gov/31742337 31742337]|[https://pubmed.ncbi.nlm.nih.gov/28514044 28514044]|[https://pubmed.ncbi.nlm.nih.gov/33014816 33014816]|[https://pubmed.ncbi.nlm.nih.gov/28708980 28708980]|[https://pubmed.ncbi.nlm.nih.gov/27432485 27432485]|[https://pubmed.ncbi.nlm.nih.gov/33050853 33050853]|[https://pubmed.ncbi.nlm.nih.gov/26045765 26045765]|[https://pubmed.ncbi.nlm.nih.gov/27542280 27542280]|[https://pubmed.ncbi.nlm.nih.gov/24411673 24411673]|[https://pubmed.ncbi.nlm.nih.gov/27760846 27760846]|[https://pubmed.ncbi.nlm.nih.gov/30115016 30115016]|[https://pubmed.ncbi.nlm.nih.gov/1410473 1410473]|[https://pubmed.ncbi.nlm.nih.gov/29802864 29802864]|[https://pubmed.ncbi.nlm.nih.gov/29669308 29669308]|[https://pubmed.ncbi.nlm.nih.gov/29251002 29251002]|[https://pubmed.ncbi.nlm.nih.gov/32541028 32541028]|[https://pubmed.ncbi.nlm.nih.gov/31019509 31019509]|[https://pubmed.ncbi.nlm.nih.gov/1582597 1582597]|[https://pubmed.ncbi.nlm.nih.gov/2981150 2981150]|[https://pubmed.ncbi.nlm.nih.gov/10842187 10842187]|[https://pubmed.ncbi.nlm.nih.gov/29638123 29638123]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22367369 22367369] [https://pubmed.ncbi.nlm.nih.gov/22367369 22367369]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10778170 10778170] [https://pubmed.ncbi.nlm.nih.gov/10778170 10778170]]|[https://pubmed.ncbi.nlm.nih.gov/1510031 1510031]|[https://pubmed.ncbi.nlm.nih.gov/19372570 19372570]|[https://pubmed.ncbi.nlm.nih.gov/20641477 20641477]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/16149605 16149605] [https://pubmed.ncbi.nlm.nih.gov/16149605 16149605]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15770530 15770530] [https://pubmed.ncbi.nlm.nih.gov/15770530 15770530]]|[https://pubmed.ncbi.nlm.nih.gov/27856425 27856425]|[https://pubmed.ncbi.nlm.nih.gov/23814067 23814067]|[https://pubmed.ncbi.nlm.nih.gov/28068458 28068458]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32134186 32134186] [https://pubmed.ncbi.nlm.nih.gov/32134186 32134186]]|[https://pubmed.ncbi.nlm.nih.gov/8174100 8174100]|[https://pubmed.ncbi.nlm.nih.gov/10571017 10571017]|[https://pubmed.ncbi.nlm.nih.gov/27453399 27453399]|[https://pubmed.ncbi.nlm.nih.gov/1727666 1727666]|[https://pubmed.ncbi.nlm.nih.gov/23740330 23740330] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/10328552 10328552]|[https://pubmed.ncbi.nlm.nih.gov/23408949 23408949]|[https://pubmed.ncbi.nlm.nih.gov/31927399 31927399]|[https://pubmed.ncbi.nlm.nih.gov/26601230 26601230]|[https://pubmed.ncbi.nlm.nih.gov/28279343 28279343]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32527016 32527016] [https://pubmed.ncbi.nlm.nih.gov/32527016 32527016]]|[https://pubmed.ncbi.nlm.nih.gov/30831115 30831115]|[https://pubmed.ncbi.nlm.nih.gov/27318698 27318698]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9207264 9207264] [https://pubmed.ncbi.nlm.nih.gov/9207264 9207264]]|[https://pubmed.ncbi.nlm.nih.gov/23828675 23828675]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29527514 29527514] [https://pubmed.ncbi.nlm.nih.gov/29527514 29527514]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1615929 1615929] [https://pubmed.ncbi.nlm.nih.gov/1615929 1615929]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2385097 2385097] [https://pubmed.ncbi.nlm.nih.gov/2385097 2385097]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2579997 2579997] [https://pubmed.ncbi.nlm.nih.gov/2579997 2579997]]|[https://pubmed.ncbi.nlm.nih.gov/25516619 25516619]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3677023 3677023] [https://pubmed.ncbi.nlm.nih.gov/3677023 3677023]]|[https://pubmed.ncbi.nlm.nih.gov/8509439 8509439]|[https://pubmed.ncbi.nlm.nih.gov/19832116 19832116]|[https://pubmed.ncbi.nlm.nih.gov/15270746 15270746]|[https://pubmed.ncbi.nlm.nih.gov/3166398 3166398]|[https://pubmed.ncbi.nlm.nih.gov/30909206 30909206]|[https://pubmed.ncbi.nlm.nih.gov/7718581 7718581]|[https://pubmed.ncbi.nlm.nih.gov/18400963 18400963]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29751628 29751628] [https://pubmed.ncbi.nlm.nih.gov/29751628 29751628]]|[https://pubmed.ncbi.nlm.nih.gov/8982241 8982241]|[https://pubmed.ncbi.nlm.nih.gov/30284922 30284922]|[https://pubmed.ncbi.nlm.nih.gov/24576035 24576035]|[https://pubmed.ncbi.nlm.nih.gov/30974776 30974776]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9098001 9098001] [https://pubmed.ncbi.nlm.nih.gov/9098001 9098001]]|[https://pubmed.ncbi.nlm.nih.gov/31768613 31768613]|[https://pubmed.ncbi.nlm.nih.gov/1651804 1651804]|[https://pubmed.ncbi.nlm.nih.gov/25428879 25428879]|[https://pubmed.ncbi.nlm.nih.gov/15946883 15946883]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30298790 30298790] [https://pubmed.ncbi.nlm.nih.gov/30298790 30298790]]|[https://pubmed.ncbi.nlm.nih.gov/30544260 30544260]|[https://pubmed.ncbi.nlm.nih.gov/29197783 29197783]|[https://pubmed.ncbi.nlm.nih.gov/8632739 8632739]|[https://pubmed.ncbi.nlm.nih.gov/7679772 7679772]|[https://pubmed.ncbi.nlm.nih.gov/18666312 18666312]|[https://pubmed.ncbi.nlm.nih.gov/20231766 20231766]|[https://pubmed.ncbi.nlm.nih.gov/29922666 29922666]|95124|[https://pubmed.ncbi.nlm.nih.gov/2247887 2247887]|[https://pubmed.ncbi.nlm.nih.gov/21519121 21519121]|[https://pubmed.ncbi.nlm.nih.gov/25153235 25153235]|[https://pubmed.ncbi.nlm.nih.gov/28751211 28751211] <br>
'''definition''' : Tn anitigen or alpha-galnac or N-Acetylgalactosamine is an N-acetyl-D-galactosamine having alpha-configuration at the anomeric centre. It has a role as an epitope. It derives from an alpha-D-galactosamine.[CHEBI:40356,HMDB[https://pubmed.ncbi.nlm.nih.gov/0000212 0000212]] <br>
'''definition''' :  <br>
  '''term_xref''' : GTC:G57321FI|GlycoEpitope:EP0021|CID:84265|CHEBI:40356|HMDB[https://pubmed.ncbi.nlm.nih.gov/0000212 0000212]|GlycoMotif:GGM.000008  <br>
  '''term_xref''' : GlycoMotif:GGM.000021|SugarBind_Ligand:146|GTC:G39211DH|CID:[https://pubmed.ncbi.nlm.nih.gov/45480568 45480568]|CHEBI:59440 <br>
  '''synonyms''' : <br>
  '''synonyms''' : Le(b)|Lewis(b)|Le^b <br>
  '''function''' : lymphatic metastasis[GlycoEpitope:EP0021]|tube formation in Drosophila development[GlycoEpitope:EP0021]|modulation of malignant phenotype (gastric carcinoma cell)[GlycoEpitope:EP0021]|correlation with tumor stage, lymphatic invasion and lymph node matastasis[GlycoEpitope:EP0021] <br>
  '''function''' : possible receptor for Helicobacter pylori[https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/blood-group-lewis-system<nowiki>] </nowiki><br>
  '''disease_associations''' : breast cancer[GlycoEpitope:EP0021]|cervical cancer[GlycoEpitope:EP0021]|colon cancer[GlycoEpitope:EP0021]|colorectal cancer[GlycoEpitope:EP0021]|fibrosarcoma[GlycoEpitope:EP0021]|gastric cancer[GlycoEpitope:EP0021]|liver cancer[GlycoEpitope:EP0021]|ovarian cancer[GlycoEpitope:EP0021]|pancreas cancer[GlycoEpitope:EP0021]|prostate cancer[GlycoEpitope:EP0021]|Tn syndorome[GlycoEpitope:EP0021]|Barrett'sesophagus[GlycoEpitope:EP0021]|Schindler/Kanzaki desease (alpha-N acetylgalactosaminidase deficiency)[GlycoEpitope:EP0021]. <br>
  '''disease_associations''' : Gastroenteritis[SugarBind_Ligand:146] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000121===
===GSD000168===
  '''term (main_entry)''' : Lewis x <br>
  '''term (main_entry)''' : Triantennary <br>
  '''glycan_dictionary_accession''' : GSD000121 <br>
  '''glycan_dictionary_accession''' : GSD000168 <br>
'''glytoucan_accession ''' : [https://www.glygen.org/glycan/G00051MO G00051MO] <br>
'''term_in_sentence''' : In particular, the observation of oxonium ions at m/z 512.2 and 803.2 is useful for probing outer non-reducing terminal fucosylation, which represented carbohydrate structures consisting of Hex Hex , dHex Hex , and HexNAc , and NeuNAc , Hex Hex , dHex Hex , and HexNAc , respectively, from which the Lewis X structure (Galbeta1-4(Fucalpha1-3)GlcNAc) was readily deduced.[PMID:[https://pubmed.ncbi.nlm.nih.gov/15536627 15536627]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/15536627 15536627]|[https://pubmed.ncbi.nlm.nih.gov/31666308 31666308]|[https://pubmed.ncbi.nlm.nih.gov/29019053 29019053]|[https://pubmed.ncbi.nlm.nih.gov/28296340 28296340]|[https://pubmed.ncbi.nlm.nih.gov/29593094 29593094]|[https://pubmed.ncbi.nlm.nih.gov/17607374 17607374]|[https://pubmed.ncbi.nlm.nih.gov/16581086 16581086]|[https://pubmed.ncbi.nlm.nih.gov/20858014 20858014]|[https://pubmed.ncbi.nlm.nih.gov/19962782 19962782]|[https://pubmed.ncbi.nlm.nih.gov/7912739 7912739]|[https://pubmed.ncbi.nlm.nih.gov/25121780 25121780]|[https://pubmed.ncbi.nlm.nih.gov/24059473 24059473]|[https://pubmed.ncbi.nlm.nih.gov/29210428 29210428]|[https://pubmed.ncbi.nlm.nih.gov/31276881 31276881]|[https://pubmed.ncbi.nlm.nih.gov/9015359 9015359]|[https://pubmed.ncbi.nlm.nih.gov/7628844 7628844]|[https://pubmed.ncbi.nlm.nih.gov/7499837 7499837]|[https://pubmed.ncbi.nlm.nih.gov/16850248 16850248]|[https://pubmed.ncbi.nlm.nih.gov/28425129 28425129]|[https://pubmed.ncbi.nlm.nih.gov/28869691 28869691]|[https://pubmed.ncbi.nlm.nih.gov/19576189 19576189]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10223649 10223649] [https://pubmed.ncbi.nlm.nih.gov/10223649 10223649]]|[https://pubmed.ncbi.nlm.nih.gov/22593503 22593503]|[https://pubmed.ncbi.nlm.nih.gov/15632313 15632313]|[https://pubmed.ncbi.nlm.nih.gov/27198630 27198630]|[https://pubmed.ncbi.nlm.nih.gov/26582608 26582608]|[https://pubmed.ncbi.nlm.nih.gov/11500392 11500392]|[https://pubmed.ncbi.nlm.nih.gov/31256373 31256373]|[https://pubmed.ncbi.nlm.nih.gov/23399157 23399157]|[https://pubmed.ncbi.nlm.nih.gov/21984435 21984435]|[https://pubmed.ncbi.nlm.nih.gov/26244810 26244810]|[https://pubmed.ncbi.nlm.nih.gov/26162743 26162743]|[https://pubmed.ncbi.nlm.nih.gov/17335083 17335083]|[https://pubmed.ncbi.nlm.nih.gov/15388363 15388363]|[https://pubmed.ncbi.nlm.nih.gov/9556613 9556613]|[https://pubmed.ncbi.nlm.nih.gov/10760152 10760152]|[https://pubmed.ncbi.nlm.nih.gov/11267844 11267844]|[https://pubmed.ncbi.nlm.nih.gov/20876654 20876654]|[https://pubmed.ncbi.nlm.nih.gov/12131290 12131290] <br>
'''definition''' : A Lewis blood group antigen with structure α-L-Fucp-(1→3)-[β-D-Galp-(1→4)]-D-GlcpNAc where the glucosamine at the reducing end has β-configuration at its anomeric centre. Commonly known as Lewis x trisaccharide or Lex.[CHEBI:59294] <br>
'''term_xref''' : GTC:G00051MO |GlycoEpitope:EP0011|CID:[https://pubmed.ncbi.nlm.nih.gov/44611539 44611539]|CHEBI:59294|GlycoMotif:GGM.000018 <br>
'''synonyms''' : Lex|Galbeta1-4(Fucalpha1-3)GlcNAc|Lewis x trisaccharide|Le(X)|Le^x|SSEA-1 <br>
'''function''' : Involved in carbohydrate-carbohydrate interaction[Glycoepitope:EP0011].|Also implicated in apoptosis.[Glycoepitope:EP0011]|influence antigenic presentation and interfere with pathogen transfer in breastfed infants.[Glycoepitope:EP0011] <br>
'''disease_associations''' : acute leukemia[GlycoEpitope:EP0011]|lymphoma[GlycoEpitope:EP0011] <br>
'''wikipedia''' :  <br>
'''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
 
 
===GSD000122===
[[File:G00052MO.png|alt=|thumb|G00052MO]]
'''term (main_entry)''' : Lewis y <br>
'''glycan_dictionary_accession''' : GSD000122 <br>
'''glytoucan_accession ''' : [https://www.glygen.org/glycan/G00052MO G00052MO] <br>
'''term_in_sentence''' : In conclusion, Lewis y antigen and CD147 were significantly upregulated in ovarian tumors, and the altered expression of Lewis y may cause changes in CD147.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30816446 30816446] [https://pubmed.ncbi.nlm.nih.gov/30816446 30816446]]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30816446 30816446] [https://pubmed.ncbi.nlm.nih.gov/30816446 30816446]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20003467 20003467] [https://pubmed.ncbi.nlm.nih.gov/20003467 20003467]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24692145 24692145] [https://pubmed.ncbi.nlm.nih.gov/24692145 24692145]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24998328 24998328] [https://pubmed.ncbi.nlm.nih.gov/24998328 24998328]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25726913 25726913] [https://pubmed.ncbi.nlm.nih.gov/25726913 25726913]]|[https://pubmed.ncbi.nlm.nih.gov/29299130 29299130]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30816446 30816446] [https://pubmed.ncbi.nlm.nih.gov/30816446 30816446]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20003467 20003467] [https://pubmed.ncbi.nlm.nih.gov/20003467 20003467]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24692145 24692145] [https://pubmed.ncbi.nlm.nih.gov/24692145 24692145]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24998328 24998328] [https://pubmed.ncbi.nlm.nih.gov/24998328 24998328]]|[https://pubmed.ncbi.nlm.nih.gov/20127027 20127027]|[https://pubmed.ncbi.nlm.nih.gov/22138668 22138668]|[https://pubmed.ncbi.nlm.nih.gov/23894390 23894390]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25726913 25726913] [https://pubmed.ncbi.nlm.nih.gov/25726913 25726913]]|[https://pubmed.ncbi.nlm.nih.gov/25416440 25416440]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27646625 27646625] [https://pubmed.ncbi.nlm.nih.gov/27646625 27646625]]|[https://pubmed.ncbi.nlm.nih.gov/23725446 23725446]|[https://pubmed.ncbi.nlm.nih.gov/21294926 21294926]|[https://pubmed.ncbi.nlm.nih.gov/22312289 22312289]|[https://pubmed.ncbi.nlm.nih.gov/25973320 25973320]|[https://pubmed.ncbi.nlm.nih.gov/23242548 23242548]|[https://pubmed.ncbi.nlm.nih.gov/30328452 30328452]|[https://pubmed.ncbi.nlm.nih.gov/21119363 21119363]|[https://pubmed.ncbi.nlm.nih.gov/29130097 29130097]|[https://pubmed.ncbi.nlm.nih.gov/23443083 23443083]|[https://pubmed.ncbi.nlm.nih.gov/23708102 23708102]|[https://pubmed.ncbi.nlm.nih.gov/28671040 28671040]|[https://pubmed.ncbi.nlm.nih.gov/19715603 19715603]|[https://pubmed.ncbi.nlm.nih.gov/23468946 23468946]|[https://pubmed.ncbi.nlm.nih.gov/27723168 27723168]|[https://pubmed.ncbi.nlm.nih.gov/21747684 21747684]|[https://pubmed.ncbi.nlm.nih.gov/19771739 19771739] <br>
'''definition''' : A Lewis blood group antigen which is a branched amino tetrasaccharide with structure alpha-L-Fucp-(1->2)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-beta-D-GlcpNAc, consisting of consisting of N-acetyl-beta-D-glucosamine at the reducing end having an alpha-L-fucosyl residue attached at the 3-position and an alpha-L-fucosyl-(1→2)-beta-D-galactosyl moiety attached at the 4-position. A cancer-associated tetrasaccharide antigen which constitutes the core structure recognised by therapeutic antibody BR96. Conformational restriction around the GlcNAc residue is a key feature of its structure. It has a role as an antigen and an epitope. [CHEBI:59045]] <br>
'''term_xref''' : GTC:G00052MO|GlycoEpitope:EP0018|CID:[https://pubmed.ncbi.nlm.nih.gov/45266908 45266908]|CHEBI:59045|GlycoMotif:GGM.000019  <br>
'''synonyms''' : LeY|Le(y)|Ley|Le^y <br>
'''function''' : The expression of the fucosylated histo-blood group antigen CD174 in CD34+ hematopoietic progenitor cells and down-regulation of FUT1 in mature lymphocytes may be important factors influencing the homing process of hematopoietic stem cells to the bone marrow.[GlycoEpitope:EP0018] <br>
'''disease_associations''' : AIDS/acquired immune deficiency syndrome[GlycoEpitope:EP0018]|cholangiocarcinoma[GlycoEpitope:EP0018]|hepatocellular carcinoma[GlycoEpitope:EP0018] <br>
'''wikipedia''' :  <br>
'''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
 
 
===GSD000123===
'''term (main_entry)''' : Monosialylated <br>
'''glycan_dictionary_accession''' : GSD000123 <br>
  '''glytoucan_accession ''' :  <br>
  '''glytoucan_accession ''' :  <br>
  '''term_in_sentence''' : The structures of the asparagine-linked sugar chains of U- CD59 were biantennary complex type , only 4.2% of which are monosialylated.[PMID:[https://pubmed.ncbi.nlm.nih.gov/7514386 7514386]] <br>
  '''term_in_sentence''' : Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.[PMID:24992960] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/7514386 7514386]|[https://pubmed.ncbi.nlm.nih.gov/8477709 8477709]|[https://pubmed.ncbi.nlm.nih.gov/8942648 8942648]|[https://pubmed.ncbi.nlm.nih.gov/29752599 29752599]|[https://pubmed.ncbi.nlm.nih.gov/31669586 31669586]|[https://pubmed.ncbi.nlm.nih.gov/29747818 29747818]|[https://pubmed.ncbi.nlm.nih.gov/16425369 16425369]|[https://pubmed.ncbi.nlm.nih.gov/12089170 12089170]|[https://pubmed.ncbi.nlm.nih.gov/31390883 31390883]|[https://pubmed.ncbi.nlm.nih.gov/1632647 1632647]|[https://pubmed.ncbi.nlm.nih.gov/29733234 29733234]|[https://pubmed.ncbi.nlm.nih.gov/31110965 31110965]|[https://pubmed.ncbi.nlm.nih.gov/31566965 31566965]|[https://pubmed.ncbi.nlm.nih.gov/30555678 30555678]|[https://pubmed.ncbi.nlm.nih.gov/28263871 28263871]|[https://pubmed.ncbi.nlm.nih.gov/29652662 29652662]|[https://pubmed.ncbi.nlm.nih.gov/25915761 25915761]|[https://pubmed.ncbi.nlm.nih.gov/16381065 16381065]|[https://pubmed.ncbi.nlm.nih.gov/29247593 29247593]|[https://pubmed.ncbi.nlm.nih.gov/28370937 28370937]|[https://pubmed.ncbi.nlm.nih.gov/23896595 23896595]|[https://pubmed.ncbi.nlm.nih.gov/26633899 26633899]|[https://pubmed.ncbi.nlm.nih.gov/32155999 32155999]|[https://pubmed.ncbi.nlm.nih.gov/25261856 25261856]|[https://pubmed.ncbi.nlm.nih.gov/2737211 2737211]|[https://pubmed.ncbi.nlm.nih.gov/26945091 26945091]|[https://pubmed.ncbi.nlm.nih.gov/27065039 27065039]|[https://pubmed.ncbi.nlm.nih.gov/26784838 26784838]|[https://pubmed.ncbi.nlm.nih.gov/26582205 26582205] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/24992960 24992960]|[https://pubmed.ncbi.nlm.nih.gov/27025342 27025342]|[https://pubmed.ncbi.nlm.nih.gov/29642865 29642865]|[https://pubmed.ncbi.nlm.nih.gov/29456020 29456020]|[https://pubmed.ncbi.nlm.nih.gov/26914862 26914862]|[https://pubmed.ncbi.nlm.nih.gov/26926155 26926155]|[https://pubmed.ncbi.nlm.nih.gov/26299345 26299345]|[https://pubmed.ncbi.nlm.nih.gov/28981809 28981809]|[https://pubmed.ncbi.nlm.nih.gov/18395704 18395704]|[https://pubmed.ncbi.nlm.nih.gov/2211710 2211710]|[https://pubmed.ncbi.nlm.nih.gov/23461434 23461434]|[https://pubmed.ncbi.nlm.nih.gov/18327885 18327885]|[https://pubmed.ncbi.nlm.nih.gov/15264862 15264862]|[https://pubmed.ncbi.nlm.nih.gov/22954207 22954207]|[https://pubmed.ncbi.nlm.nih.gov/9061362 9061362]|[https://pubmed.ncbi.nlm.nih.gov/16581187 16581187]|[https://pubmed.ncbi.nlm.nih.gov/26537865 26537865]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3979568 3979568] [https://pubmed.ncbi.nlm.nih.gov/3979568 3979568]]|[https://pubmed.ncbi.nlm.nih.gov/28129130 28129130]|[https://pubmed.ncbi.nlm.nih.gov/7679920 7679920]|[https://pubmed.ncbi.nlm.nih.gov/8068017 8068017]|[https://pubmed.ncbi.nlm.nih.gov/7783116 7783116]|[https://pubmed.ncbi.nlm.nih.gov/3857231 3857231]|[https://pubmed.ncbi.nlm.nih.gov/20540518 20540518]|[https://pubmed.ncbi.nlm.nih.gov/1706936 1706936]|[https://pubmed.ncbi.nlm.nih.gov/2430615 2430615]|[https://pubmed.ncbi.nlm.nih.gov/8078981 8078981]|[https://pubmed.ncbi.nlm.nih.gov/2211711 2211711]|[https://pubmed.ncbi.nlm.nih.gov/6767476 6767476]|[https://pubmed.ncbi.nlm.nih.gov/3814128 3814128]|[https://pubmed.ncbi.nlm.nih.gov/2597120 2597120]|[https://pubmed.ncbi.nlm.nih.gov/7451505 7451505]|[https://pubmed.ncbi.nlm.nih.gov/8204583 8204583]|[https://pubmed.ncbi.nlm.nih.gov/20619452 20619452]|[https://pubmed.ncbi.nlm.nih.gov/10460831 10460831]|[https://pubmed.ncbi.nlm.nih.gov/1924399 1924399]|[https://pubmed.ncbi.nlm.nih.gov/6643471 6643471]|[https://pubmed.ncbi.nlm.nih.gov/31809011 31809011]|[https://pubmed.ncbi.nlm.nih.gov/30042045 30042045]|[https://pubmed.ncbi.nlm.nih.gov/2477056 2477056]|[https://pubmed.ncbi.nlm.nih.gov/7882496 7882496]|[https://pubmed.ncbi.nlm.nih.gov/2430614 2430614]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2551687 2551687] [https://pubmed.ncbi.nlm.nih.gov/2551687 2551687]]|[https://pubmed.ncbi.nlm.nih.gov/2426141 2426141]|[https://pubmed.ncbi.nlm.nih.gov/2065052 2065052]|[https://pubmed.ncbi.nlm.nih.gov/28988716 28988716]|[https://pubmed.ncbi.nlm.nih.gov/31144994 31144994]|[https://pubmed.ncbi.nlm.nih.gov/26966183 26966183]|[https://pubmed.ncbi.nlm.nih.gov/29809215 29809215] <br>
  '''definition''' : A glycan that have the addition of one sialic acid residues. <br>
  '''definition''' : Type of N-linked glycan in which three antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The three antennae can be be initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 1 GlcNAc to the _6 Man (at the 2 position) of the trimannosyl core or 1 on the _3 and 2 on the _6 Man (at the 2 and 6 positions). Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:[https://www.ncbi.nlm.nih.gov/books/NBK453019/ Glossary]] <br>
  '''term_xref''' :  <br>
  '''term_xref''' :  <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' : appears in bovine brain gangliosides.[PMID: [https://pubmed.ncbi.nlm.nih.gov/29752599 29752599]] <br>
  '''function''' : <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
Line 349: Line 271:




===GSD000124===
===GSD000169===
  '''term (main_entry)''' : Monosialyl-biantennary <br>
  '''term (main_entry)''' : Triantennary complex <br>
  '''glycan_dictionary_accession''' : GSD000124 <br>
  '''glycan_dictionary_accession''' : GSD000169 <br>
  '''glytoucan_accession ''' :  <br>
  '''glytoucan_accession ''' :  <br>
  '''term_in_sentence''' : In contrast, the sugar chain structure of HCC highly specific AFP isoform was found to comprise a monosialyl-biantennary sugar chain with additional fucosylation of the proximal N-acetylglucosamine.[PMID:[https://pubmed.ncbi.nlm.nih.gov/7686446 7686446]] <br>
  '''term_in_sentence''' : Fucosylated biantennary complex-type and small amounts (less than 5%) of triantennary complex-type structures were identified on the glycosylated asparagine residues using sequential exoglycosidase and endoglycosidase digestions combined with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).[PMID:[https://pubmed.ncbi.nlm.nih.gov/9118998 9118998]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/7686446 7686446]|[https://pubmed.ncbi.nlm.nih.gov/1374031 1374031]|[https://pubmed.ncbi.nlm.nih.gov/9648261 9648261]|[https://pubmed.ncbi.nlm.nih.gov/10460833 10460833]|[https://pubmed.ncbi.nlm.nih.gov/19524219 19524219]|[https://pubmed.ncbi.nlm.nih.gov/10207016 10207016]|[https://pubmed.ncbi.nlm.nih.gov/15797573 15797573]|[https://pubmed.ncbi.nlm.nih.gov/15218190 15218190] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/9118998 9118998]|[https://pubmed.ncbi.nlm.nih.gov/9061362 9061362]|[https://pubmed.ncbi.nlm.nih.gov/18395704 18395704]|[https://pubmed.ncbi.nlm.nih.gov/3814128 3814128]|[https://pubmed.ncbi.nlm.nih.gov/7451505 7451505]|[https://pubmed.ncbi.nlm.nih.gov/10460831 10460831]|[https://pubmed.ncbi.nlm.nih.gov/26926155 26926155]|[https://pubmed.ncbi.nlm.nih.gov/26966183 26966183]|[https://pubmed.ncbi.nlm.nih.gov/16581187 16581187]|[https://pubmed.ncbi.nlm.nih.gov/16973123 16973123]|[https://pubmed.ncbi.nlm.nih.gov/8204583 8204583]|[https://pubmed.ncbi.nlm.nih.gov/29809215 29809215]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11114588 11114588] [https://pubmed.ncbi.nlm.nih.gov/11114588 11114588]]|[https://pubmed.ncbi.nlm.nih.gov/31322324 31322324]|[https://pubmed.ncbi.nlm.nih.gov/15044389 15044389]|[https://pubmed.ncbi.nlm.nih.gov/16372382 16372382]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/8251489 8251489] [https://pubmed.ncbi.nlm.nih.gov/8251489 8251489]]|[https://pubmed.ncbi.nlm.nih.gov/8299583 8299583]|[https://pubmed.ncbi.nlm.nih.gov/1555586 1555586]|[https://pubmed.ncbi.nlm.nih.gov/7509658 7509658]|[https://pubmed.ncbi.nlm.nih.gov/1569060 1569060]|[https://pubmed.ncbi.nlm.nih.gov/16261636 16261636] <br>
  '''definition''' : A biantennary glycan with two GlcNAc branches linked to the core and the addition of one sialic acid residues. <br>
  '''definition''' : A complex N-glycan that has three branches attached to the non-reducing terminal Man residues of the trimannosyl core.[CHEBI:156252]  Each branch is initiated with a GlcNAc and can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. <br>
  '''term_xref''' : <br>
  '''term_xref''' : CHEBI:156252 <br>
  '''synonyms''' : monosialyl biantennary|sialylated diantennary|sialylated biantennary <br>
  '''synonyms''' : Triantennary complex-type <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453030/ Chapter 10]<br>




===GSD000125===
===GSD000170===
  '''term (main_entry)''' : Monosialyl-Gb5 <br>
  '''term (main_entry)''' : Triantennary N-glycans <br>
  '''glycan_dictionary_accession''' : GSD000125 <br>
  '''glycan_dictionary_accession''' : GSD000170 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G32254QI G32254QI] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : Thus, malignancy of MCF-7 is highly dependent on monosialyl-Gb5, and its activation of cSrc and FAK in GEM.[PMID:[https://pubmed.ncbi.nlm.nih.gov/12401210 12401210]] <br>
  '''term_in_sentence''' : Increased expression of the high-mannose M6N2 and NeuAc3H3N3M3N2F tri-antennary N-glycans in cholangiocarcinoma.[PMID:29399163] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/12401210 12401210]|[https://pubmed.ncbi.nlm.nih.gov/16995838 16995838]|[https://pubmed.ncbi.nlm.nih.gov/27318475 27318475] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/29399163 29399163]|[https://pubmed.ncbi.nlm.nih.gov/22325877 22325877]|[https://pubmed.ncbi.nlm.nih.gov/18439991 18439991]|[https://pubmed.ncbi.nlm.nih.gov/24873509 24873509]|[https://pubmed.ncbi.nlm.nih.gov/11454001 11454001] <br>
  '''definition''' : alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp is a linear amino hexasaccharide comprising β-D-glucose at the reducing end with at the 4-position a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-α-D-galactosyl-(1→4)-β-D-galactosyl moiety, α(2→3)-sialylated at the terminal galactosyl residue.[CHEBI:62313] <br>
  '''definition''' : Type of N-linked glycan in which three antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The three antennae can be be initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 1 GlcNAc to the _6 Man (at the 2 position) of the trimannosyl core or 1 on the _3 and 2 on the _6 Man (at the 2 and 6 positions). Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:[https://www.ncbi.nlm.nih.gov/books/NBK453019/ Glossary]]  <br>
'''term_xref''' : GTC:G32254QI|GlycoEpitope:EP0099|GlycoMotif:GGM.000080|CID:[https://pubmed.ncbi.nlm.nih.gov/73427363 73427363]|CHEBI:62313 <br>
'''term_xref''' :  <br>
  '''synonyms''' : GL-7 globoseries ganglioside (SSEA-4)|Monosialyl Gb5|Sialosyl galactosyl globoside|GL-7 globoseries ganglioside|SSEA-4 <br>
  '''synonyms''' : <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' : renal cell carcinoma/RCC[GlycoEpitope:EP0099] <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000126===
===GSD000171===
[[File:G80193TN.png|thumb|G80193TN]]
  '''term (main_entry)''' : Triantennary sialylated <br>
  '''term (main_entry)''' : Mono-sulfated globopentaosylceramide <br>
  '''glycan_dictionary_accession''' : GSD000171 <br>
  '''glycan_dictionary_accession''' : GSD000126 <br>
  '''glytoucan_accession ''' : <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G80193TN G80193TN] <br>
  '''term_in_sentence''' : LC-ESIMS/MS analysis revealed that both light chain and heavy chain were N-glycosylated mainly by A2S2 but also by triantennary sialylated glycans.[PMID:[https://pubmed.ncbi.nlm.nih.gov/18642129 18642129]] <br>
  '''term_in_sentence''' : Mono-sulfated globopentaosylceramide from human kidney.[PMID:[https://pubmed.ncbi.nlm.nih.gov/2777788 2777788]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/18642129 18642129]|[https://pubmed.ncbi.nlm.nih.gov/31964828 31964828]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3979568 3979568] [https://pubmed.ncbi.nlm.nih.gov/3979568 3979568]]|[https://pubmed.ncbi.nlm.nih.gov/27936604 27936604]|[https://pubmed.ncbi.nlm.nih.gov/23681398 23681398]|[https://pubmed.ncbi.nlm.nih.gov/21538882 21538882]|[https://pubmed.ncbi.nlm.nih.gov/7579793 7579793]|[https://pubmed.ncbi.nlm.nih.gov/7613477 7613477]|[https://pubmed.ncbi.nlm.nih.gov/2223825 2223825]|[https://pubmed.ncbi.nlm.nih.gov/3539023 3539023]|[https://pubmed.ncbi.nlm.nih.gov/3674882 3674882] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/2777788 2777788] <br>
  '''definition''' : A triantennary glycan with three GlcNAc branches linked to the core and the addition of one sialic acid residues. <br>
  '''definition''' : <br>
  '''term_xref''' : <br>
  '''term_xref''' : GlycoMotif:GGM.000072|GTC:G80193TN <br>
  '''synonyms''' : <br>
  '''synonyms''' : Monosulfated globopentaosylceramide <br>
  '''function''' : Appears in human serotransferrin.[PMID: [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3979568 3979568] [https://pubmed.ncbi.nlm.nih.gov/3979568 3979568]]] <br>
  '''function''' : <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
Line 395: Line 316:




===GSD000127===
===GSD000172===
  '''term (main_entry)''' : Mono-sulfated globotetraosylceramide <br>
  '''term (main_entry)''' : Triantennary trisialylated fucosylated <br>
  '''glycan_dictionary_accession''' : GSD000127 <br>
  '''glycan_dictionary_accession''' : GSD000172 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G05297EK G05297EK] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : Mono-sulfated globotetraosylceramide from human kidney.[PMID:[https://pubmed.ncbi.nlm.nih.gov/2559078 2559078]] <br>
  '''term_in_sentence''' : Diantennary monosialylated glycans and triantennary trisialylated fucosylated and non-fucosylated structures have also been identified.[PMID:[https://pubmed.ncbi.nlm.nih.gov/17591618 17591618]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/2559078 2559078] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/17591618 17591618] <br>
  '''definition''' : <br>
  '''definition''' : A triantennary glycan with three GlcNAc branches linked to the core and the addition of three sialic acid residues and fucose added. <br>
  '''term_xref''' : GlycoMotif:GGM.000073|GTC:G05297EK<br>
  '''term_xref''' : <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
Line 410: Line 331:




===GSD000128===
===GSD000173===
  '''term (main_entry)''' : N-acetyl GM2 <br>
  '''term (main_entry)''' : Trifucosyl Lewis b antigen <br>
  '''glycan_dictionary_accession''' : GSD000128 <br>
  '''glycan_dictionary_accession''' : GSD000173 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G79389NT G79389NT] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G74578MX G74578MX] <br>
  '''term_in_sentence''' : The appearance of the N-acetyl GM2 antigen correlated well with the degree of differentiation of the cancer cells in patients with squamous cell carcinoma and adenocarcinoma of the lung.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3167861 3167861] [https://pubmed.ncbi.nlm.nih.gov/3167861 3167861]]] <br>
  '''term_in_sentence''' : Extended type-1 chain glycosphingolipid antigens. Isolation and characterization of trifucosyl-Leb antigen (III4V4VI2Fuc3Lc6)[PMID:[https://pubmed.ncbi.nlm.nih.gov/1735443 1735443]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3167861 3167861] [https://pubmed.ncbi.nlm.nih.gov/3167861 3167861]]|[https://pubmed.ncbi.nlm.nih.gov/2153431 2153431]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25673107 25673107] [https://pubmed.ncbi.nlm.nih.gov/25673107 25673107]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/1735443 1735443] <br>
  '''definition''' : beta-D-GalpNAc-(1->4)-[alpha-Neup5Ac-(2->3)]-beta-D-Galp-(1->4)-beta-D-Glcp is a branched amino tetrasaccharide consisting of the linear sequence β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to the galactose via an α-(2→3) linkage. Corresponds to the carbohydrate portion of ganglioside GM2.[CHEBI:59220] <br>
  '''definition''' : N-[(2R,3R,4R,5S,6R)-4-[(2R,3R,4S,5S,6R)-4-[(2S,3R,4R,5S,6R)-3-Acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-5-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxy-6-(hydroxymethyl)-5-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]acetamide is an amino sugar.[CHEBI:153783] <br>
  '''term_xref''' : GTC:G79389NT|GlycoEpitope:EP0051|CID:[https://pubmed.ncbi.nlm.nih.gov/45266845 45266845]|CHEBI:59220 <br>
  '''term_xref''' : GlycoEpitope:EP0092|GTC:G74578MX|CID:[https://pubmed.ncbi.nlm.nih.gov/91845957 91845957]|CHEBI:153783 <br>
  '''synonyms''' : <br>
  '''synonyms''' : trifucosyl-Leb antigen <br>
  '''function''' : The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.[CHEBI:59220] <br>
  '''function''' : cancer-associated antigen[GlycoEpitope: EP0092] <br>
  '''disease_associations''' : lung adenocarcinoma[GlycoEpitope:EP0051]|embryonal carcinoma[GlycoEpitope:EP0051]|germ cell tumor[GlycoEpitope:EP0051]|teratocarcinoma[GlycoEpitope:EP0051]|squamous cell carcinoma[GlycoEpitope:EP0051] <br>
  '''disease_associations''' : colonic cancer[GlycoEpitope: EP0092]|endometrial cancer[GlycoEpitope: EP0092]|liver cancer[GlycoEpitope: EP0092]|pancreatic cancer[GlycoEpitope: EP0092]|rectal cancer[GlycoEpitope: EP0092] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000129===
===GSD000174===
  '''term (main_entry)''' : N-acetyllactosamine (Type 2)<br>
  '''term (main_entry)''' : Trifucosyl lewis y <br>
  '''glycan_dictionary_accession''' : GSD000129 <br>
  '''glycan_dictionary_accession''' : GSD000174 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G00055MO G00055MO] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G74917JX G74917JX] <br>
  '''term_in_sentence''' : Utilising a fast and sensitive screening method based on imidazolium-tagged probes, we report unprecedented reversible activity of bacterial beta1,4-galactosyltransferases to catalyse the transgalactosylation from lactose to N-acetylglucosamine to form N-acetyllactosamine in the presence of UDP.[PMID:[https://pubmed.ncbi.nlm.nih.gov/31165848 31165848]] <br>
  '''term_in_sentence''' : The third, major component, common in all eight cases, has been identified as trifucosyl Ley (lactotrifucononaosylceramide, III3FucV3FucVI2FucnLc6, Structure 2 below) based on 1H NMR spectroscopy, methylation analysis, and direct-probe electron-impact mass spectrometry.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3733752 3733752] [https://pubmed.ncbi.nlm.nih.gov/3733752 3733752]]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/31165848 31165848]|[https://pubmed.ncbi.nlm.nih.gov/31126011 31126011]|[https://pubmed.ncbi.nlm.nih.gov/28796164 28796164]|[https://pubmed.ncbi.nlm.nih.gov/6236210 6236210]|[https://pubmed.ncbi.nlm.nih.gov/9751793 9751793]|[https://pubmed.ncbi.nlm.nih.gov/29740087 29740087]|[https://pubmed.ncbi.nlm.nih.gov/9151975 9151975]|[https://pubmed.ncbi.nlm.nih.gov/10567443 10567443]|[https://pubmed.ncbi.nlm.nih.gov/21472942 21472942]|[https://pubmed.ncbi.nlm.nih.gov/26477523 26477523]|[https://pubmed.ncbi.nlm.nih.gov/6548353 6548353]|[https://pubmed.ncbi.nlm.nih.gov/28167527 28167527]|[https://pubmed.ncbi.nlm.nih.gov/20056550 20056550]|[https://pubmed.ncbi.nlm.nih.gov/7737204 7737204]|[https://pubmed.ncbi.nlm.nih.gov/22052010 22052010]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10223649 10223649] [https://pubmed.ncbi.nlm.nih.gov/10223649 10223649]]|[https://pubmed.ncbi.nlm.nih.gov/11323440 11323440]|[https://pubmed.ncbi.nlm.nih.gov/10420596 10420596]|[https://pubmed.ncbi.nlm.nih.gov/7766648 7766648]|[https://pubmed.ncbi.nlm.nih.gov/25257940 25257940]|[https://pubmed.ncbi.nlm.nih.gov/17977857 17977857]|[https://pubmed.ncbi.nlm.nih.gov/15556936 15556936]|[https://pubmed.ncbi.nlm.nih.gov/26541999 26541999]|[https://pubmed.ncbi.nlm.nih.gov/23650594 23650594]|[https://pubmed.ncbi.nlm.nih.gov/9692202 9692202]|[https://pubmed.ncbi.nlm.nih.gov/29429899 29429899]|[https://pubmed.ncbi.nlm.nih.gov/21062783 21062783]|[https://pubmed.ncbi.nlm.nih.gov/25034434 25034434]|[https://pubmed.ncbi.nlm.nih.gov/8985145 8985145]|[https://pubmed.ncbi.nlm.nih.gov/28503789 28503789]|[https://pubmed.ncbi.nlm.nih.gov/8720464 8720464]/ <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/3733752 3733752]|[https://pubmed.ncbi.nlm.nih.gov/2426269 2426269] <br>
  '''definition''' : N-acetyllactosamine is a beta-D-galactopyranosyl-(1→4)-N-acetyl-D-glucosamine having beta-configuration at the reducing end anomeric centre. It is also known as galb1-4glcnacb or lacnac, belongs to the class of organic compounds known as acylaminosugars. These are organic compounds containing a sugar linked to a chain through N-acyl group. N-Acetyllactosamine is an extremely weak basic (essentially neutral) compound (based on its pKa). N-Acetyllactosamine exists in all living organisms, ranging from bacteria to humans.[CHEBI:16153,HMDB0001542] <br>
  '''definition''' : A branched heptasaccharide derivative consisting of two repeating units of β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc (joined by a (1→3)-linkage) with an α-L-fucosyl residue attached at the 2-position of the galactose residue at the non-reducing end.[CHEBI:61332] <br>
  '''term_xref''' : GTC:G00055MO|CID:439271|CHEBI:16153|MeSH:C000458|GlycoMotif:GGM.000001 <br>
  '''term_xref''' : GlycoEpitope: EP0094|GTC:G74917JX|CID:[https://pubmed.ncbi.nlm.nih.gov/50909806 50909806]|CHEBI:61332 <br>
  '''synonyms''' : LacNAc|Type 2 LN <br>
  '''synonyms''' : trifucosyl Ley <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' : <br>
  '''disease_associations''' : colonic adenocarcinomia[GlycoEpitope: EP0094] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000130===
===GSD000175===
  '''term (main_entry)''' : N-Glycolyl-GM2 <br>
  '''term (main_entry)''' : Trimannosyl core <br>
  '''glycan_dictionary_accession''' : GSD000130 <br>
  '''glycan_dictionary_accession''' : GSD000175 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G56478LD G56478LD] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : The monoclonal antibodies MK2-34 and MK1-16 (both IgM), which specifically detect N-glycolyl GM2 and N-acetyl GM2, respectively, were generated by immunizing mice with liposomes containing monophosphoryl lipid A, trehalose dimycolate, and the antigenic ganglioside.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3167861 3167861] [https://pubmed.ncbi.nlm.nih.gov/3167861 3167861]]] <br>
  '''term_in_sentence''' : This glycoengineered H. polymorpha strain produced glycoproteins mainly containing trimannosyl core N-glycan (Man(3)GlcNAc(2)), which is the common core backbone of various human-type N-glycans.[PMID:[https://pubmed.ncbi.nlm.nih.gov/18320567 18320567]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/3167861 3167861] [https://pubmed.ncbi.nlm.nih.gov/3167861 3167861]]|[https://pubmed.ncbi.nlm.nih.gov/11861662 11861662]|[https://pubmed.ncbi.nlm.nih.gov/17980710 17980710]|[https://pubmed.ncbi.nlm.nih.gov/3731079 3731079]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25673107 25673107] [https://pubmed.ncbi.nlm.nih.gov/25673107 25673107]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/18320567 18320567]|[https://pubmed.ncbi.nlm.nih.gov/27629418 27629418]|[https://pubmed.ncbi.nlm.nih.gov/26514868 26514868]|[https://pubmed.ncbi.nlm.nih.gov/26821880 26821880]|[https://pubmed.ncbi.nlm.nih.gov/2477227 2477227]|[https://pubmed.ncbi.nlm.nih.gov/6213618 6213618]|[https://pubmed.ncbi.nlm.nih.gov/31747570 31747570]|[https://pubmed.ncbi.nlm.nih.gov/29273674 29273674]|[https://pubmed.ncbi.nlm.nih.gov/31064325 31064325]|[https://pubmed.ncbi.nlm.nih.gov/1291063 1291063]|[https://pubmed.ncbi.nlm.nih.gov/28353332 28353332]|[https://pubmed.ncbi.nlm.nih.gov/1421754 1421754]|[https://pubmed.ncbi.nlm.nih.gov/29666272 29666272]|[https://pubmed.ncbi.nlm.nih.gov/11421342 11421342]|[https://pubmed.ncbi.nlm.nih.gov/15648688 15648688]|[https://pubmed.ncbi.nlm.nih.gov/28179475 28179475]|[https://pubmed.ncbi.nlm.nih.gov/28903882 28903882]|[https://pubmed.ncbi.nlm.nih.gov/27189951 27189951]|[https://pubmed.ncbi.nlm.nih.gov/9455915 9455915]|[https://pubmed.ncbi.nlm.nih.gov/22768188 22768188]|[https://pubmed.ncbi.nlm.nih.gov/9254048 9254048]|[https://pubmed.ncbi.nlm.nih.gov/8721739 8721739]|[https://pubmed.ncbi.nlm.nih.gov/2249985 2249985]|[https://pubmed.ncbi.nlm.nih.gov/22933239 22933239]|[https://pubmed.ncbi.nlm.nih.gov/25629585 25629585]|[https://pubmed.ncbi.nlm.nih.gov/24489949 24489949]|[https://pubmed.ncbi.nlm.nih.gov/2981047 2981047]|[https://pubmed.ncbi.nlm.nih.gov/11067815 11067815]|[https://pubmed.ncbi.nlm.nih.gov/1729985 1729985]|[https://pubmed.ncbi.nlm.nih.gov/1710649 1710649]|[https://pubmed.ncbi.nlm.nih.gov/16672288 16672288]|[https://pubmed.ncbi.nlm.nih.gov/2719668 2719668]|[https://pubmed.ncbi.nlm.nih.gov/19003000 19003000]|[https://pubmed.ncbi.nlm.nih.gov/23025485 23025485]|[https://pubmed.ncbi.nlm.nih.gov/22500028 22500028]|[https://pubmed.ncbi.nlm.nih.gov/10409642 10409642]|[https://pubmed.ncbi.nlm.nih.gov/1325461 1325461]|[https://pubmed.ncbi.nlm.nih.gov/23136055 23136055]|[https://pubmed.ncbi.nlm.nih.gov/23085445 23085445]|[https://pubmed.ncbi.nlm.nih.gov/21656680 21656680]|[https://pubmed.ncbi.nlm.nih.gov/22448293 22448293]|[https://pubmed.ncbi.nlm.nih.gov/22132163 22132163]|[https://pubmed.ncbi.nlm.nih.gov/1425696 1425696]|[https://pubmed.ncbi.nlm.nih.gov/20696712 20696712]|[https://pubmed.ncbi.nlm.nih.gov/18056652 18056652]|[https://pubmed.ncbi.nlm.nih.gov/15084511 15084511]|[https://pubmed.ncbi.nlm.nih.gov/18633282 18633282]|[https://pubmed.ncbi.nlm.nih.gov/15814299 15814299] <br>
'''definition''' : (2S,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-3-[(2S,3R,4R,5R,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-4-yl]oxy-4-hydroxy-5-[(2-hydroxyacetyl)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of carbohydrates and carbohydrate derivatives.[CHEBI:151464] <br>
'''definition''' : A glycan that constitutes the core structure common to all high-mannose, complex, or hybrid N-glycans. The trimannosyl core composition is Man3 GlcNAc2 and includes a chitobiose at the reducing terminal which is extended by a single b-linked Man residue. The b-linked Man is branched by two additional a-linked Man residues, one at the 3 position and one at the 6 position. <br>
'''term_xref''' : GTC:G56478LD |GlycoEpitope:EP0052|CID:[https://pubmed.ncbi.nlm.nih.gov/91845742 91845742]|CHEBI:151464|GlycoEpitope:GGM.000096 <br>
'''term_xref''' : <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' : choriocarcinoma[GlycoEpitope:EP0052]|teratocarcinoma|[GlycoEpitope:EP0052]yolk sac tumor[GlycoEpitope:EP0052] <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000131===
===GSD000176===
  '''term (main_entry)''' : N-linked glycans <br>
  '''term (main_entry)''' : Trisialylated <br>
  '''glycan_dictionary_accession''' : GSD000131 <br>
  '''glycan_dictionary_accession''' : GSD000176 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G78059CC G78059CC] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : Our study identifies extracellular N-linked glycans-and the glycoprotein neurexin 1β specifically-as key modulators of neuronal uptake of αSacetyl, drawing attention to the potential therapeutic value of αSacetyl-glycan interactions.[PMID:[https://pubmed.ncbi.nlm.nih.gov/31211781 31211781]] <br>
  '''term_in_sentence''' : Many (82.7%) were found to be tetraantennary N-acetyllactosamine-type (22.8% with one, 3.6% with two and 0.4% with three N-acetyllactosamine repeats) being tetrasialylated (41%), trisialylated (29.6%) and disialylated (12.2%) |HPAE-PAD and FACE analysis suggests that they are triantennary and trisialylated with core fucosylation.[PMID:8477709] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/31211781 31211781]|[https://pubmed.ncbi.nlm.nih.gov/28384382 28384382]|[https://pubmed.ncbi.nlm.nih.gov/30305477 30305477]|[https://pubmed.ncbi.nlm.nih.gov/31364612 31364612]|[https://pubmed.ncbi.nlm.nih.gov/26899268 26899268]|[https://pubmed.ncbi.nlm.nih.gov/29945790 29945790]|[https://pubmed.ncbi.nlm.nih.gov/29652253 29652253]|[https://pubmed.ncbi.nlm.nih.gov/29723274 29723274]|[https://pubmed.ncbi.nlm.nih.gov/30962676 30962676]|[https://pubmed.ncbi.nlm.nih.gov/29778448 29778448]|[https://pubmed.ncbi.nlm.nih.gov/25325701 25325701]|[https://pubmed.ncbi.nlm.nih.gov/31100702 31100702]|[https://pubmed.ncbi.nlm.nih.gov/28898525 28898525]|[https://pubmed.ncbi.nlm.nih.gov/22944671 22944671]|[https://pubmed.ncbi.nlm.nih.gov/19277537 19277537]|[https://pubmed.ncbi.nlm.nih.gov/24473128 24473128]|[https://pubmed.ncbi.nlm.nih.gov/17957771 17957771]|[https://pubmed.ncbi.nlm.nih.gov/27554083 27554083]|[https://pubmed.ncbi.nlm.nih.gov/15189166 15189166]|[https://pubmed.ncbi.nlm.nih.gov/11269317 11269317]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19577919 19577919] [https://pubmed.ncbi.nlm.nih.gov/19577919 19577919]]|[https://pubmed.ncbi.nlm.nih.gov/24303005 24303005]|[https://pubmed.ncbi.nlm.nih.gov/12042249 12042249]|[https://pubmed.ncbi.nlm.nih.gov/22191536 22191536]|[https://pubmed.ncbi.nlm.nih.gov/28324664 28324664]|[https://pubmed.ncbi.nlm.nih.gov/25965797 25965797]|[https://pubmed.ncbi.nlm.nih.gov/25434632 25434632]|[https://pubmed.ncbi.nlm.nih.gov/30484244 30484244]|[https://pubmed.ncbi.nlm.nih.gov/28110657 28110657]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29865036 29865036] [https://pubmed.ncbi.nlm.nih.gov/29865036 29865036]]|[https://pubmed.ncbi.nlm.nih.gov/20129637 20129637]|[https://pubmed.ncbi.nlm.nih.gov/27346875 27346875]|[https://pubmed.ncbi.nlm.nih.gov/30280442 30280442]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26911286 26911286] [https://pubmed.ncbi.nlm.nih.gov/26911286 26911286]]|[https://pubmed.ncbi.nlm.nih.gov/22491358 22491358]|[https://pubmed.ncbi.nlm.nih.gov/26582281 26582281]|[https://pubmed.ncbi.nlm.nih.gov/26398792 26398792]|[https://pubmed.ncbi.nlm.nih.gov/31548313 31548313]|[https://pubmed.ncbi.nlm.nih.gov/31066275 31066275]|[https://pubmed.ncbi.nlm.nih.gov/28331984 28331984]|[https://pubmed.ncbi.nlm.nih.gov/25482090 25482090]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28518173 28518173] [https://pubmed.ncbi.nlm.nih.gov/28518173 28518173]]|[https://pubmed.ncbi.nlm.nih.gov/30733536 30733536]|[https://pubmed.ncbi.nlm.nih.gov/22326428 22326428]|[https://pubmed.ncbi.nlm.nih.gov/30063825 30063825]|[https://pubmed.ncbi.nlm.nih.gov/30315103 30315103]|[https://pubmed.ncbi.nlm.nih.gov/21558494 21558494]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31676555 31676555] [https://pubmed.ncbi.nlm.nih.gov/31676555 31676555]]|[https://pubmed.ncbi.nlm.nih.gov/31256374 31256374] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/6469957 6469957]|[https://pubmed.ncbi.nlm.nih.gov/18818422 18818422]|[https://pubmed.ncbi.nlm.nih.gov/18332077 18332077]|[https://pubmed.ncbi.nlm.nih.gov/21138277 21138277]|[https://pubmed.ncbi.nlm.nih.gov/9136890 9136890]|[https://pubmed.ncbi.nlm.nih.gov/10782293 10782293]|[https://pubmed.ncbi.nlm.nih.gov/19841910 19841910]|[https://pubmed.ncbi.nlm.nih.gov/20067809 20067809]|[https://pubmed.ncbi.nlm.nih.gov/14751029 14751029]|[https://pubmed.ncbi.nlm.nih.gov/8797382 8797382]|[https://pubmed.ncbi.nlm.nih.gov/16877748 16877748]|[https://pubmed.ncbi.nlm.nih.gov/19131698 19131698]|[https://pubmed.ncbi.nlm.nih.gov/20578731 20578731]|[https://pubmed.ncbi.nlm.nih.gov/24669823 24669823]|[https://pubmed.ncbi.nlm.nih.gov/22426998 22426998]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27501865 27501865] [https://pubmed.ncbi.nlm.nih.gov/27501865 27501865]]|[https://pubmed.ncbi.nlm.nih.gov/2121479 2121479]|[https://pubmed.ncbi.nlm.nih.gov/24663386 24663386]|[https://pubmed.ncbi.nlm.nih.gov/32209427 32209427]|[https://pubmed.ncbi.nlm.nih.gov/32737218 32737218]|[https://pubmed.ncbi.nlm.nih.gov/33245334 33245334]|[https://pubmed.ncbi.nlm.nih.gov/26927318 26927318]|[https://pubmed.ncbi.nlm.nih.gov/30962676 30962676]|[https://pubmed.ncbi.nlm.nih.gov/28370937 28370937]|[https://pubmed.ncbi.nlm.nih.gov/30194503 30194503]|[https://pubmed.ncbi.nlm.nih.gov/26321095 26321095]|[https://pubmed.ncbi.nlm.nih.gov/30463578 30463578]|[https://pubmed.ncbi.nlm.nih.gov/31455764 31455764]|[https://pubmed.ncbi.nlm.nih.gov/31566965 31566965]|[https://pubmed.ncbi.nlm.nih.gov/31266306 31266306]|[https://pubmed.ncbi.nlm.nih.gov/29782424 29782424]|[https://pubmed.ncbi.nlm.nih.gov/31247951 31247951]|[https://pubmed.ncbi.nlm.nih.gov/30487799 30487799]|[https://pubmed.ncbi.nlm.nih.gov/2049094 2049094]|[https://pubmed.ncbi.nlm.nih.gov/1997323 1997323]|[https://pubmed.ncbi.nlm.nih.gov/10913832 10913832] <br>
  '''definition''' : The carbohydrate portion of a glycoprotein that has a glycan linked through the nitrogen of an asparagine side-chain.[CHEBI:59520] <br>
  '''definition''' : A glycan with three sialic acid components. <br>
  '''term_xref''' : GTC:G78059CC|CID:[https://pubmed.ncbi.nlm.nih.gov/70679232 70679232]|CHEBI:70967 <br>
  '''term_xref''' : <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' : N-glycans modulate the function of several cell surface proteins which involved in migration, adhesion and which are responsible for regulating myelination.[PMID: 25151374]|Affect transportation of the glycosylated proteins in the Golgi.[PMID: 25151374]|Affects cell-cell interaction, adhesion, expression, proper folding.[PMID: 25151374]|extracellular N-glycans act as key modulators of neuronal uptake of αacetyl [PMID: [https://pubmed.ncbi.nlm.nih.gov/31211781 31211781]]. <br>
  '''function''' : <br>
  '''disease_associations''' : Rheumatoid arthritis[PMID:17392038]|Type 1 Diabetes[PMID:29146600]|Lung Cancer[PMID: 23766031] <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
  '''essentials_of_glycobiology''' : <br>




===GSD000132===
===GSD000177===
  '''term (main_entry)''' : Nonfucosylated <br>
  '''term (main_entry)''' : Trisialylated complex-type oligosaccharide-alditols <br>
  '''glycan_dictionary_accession''' : GSD000132 <br>
  '''glycan_dictionary_accession''' : GSD000177 <br>
  '''glytoucan_accession ''' :  <br>
  '''glytoucan_accession ''' :  <br>
  '''term_in_sentence''' : In the carbohydrate moiety , alpha-subunit from normal pregnancy hCG contained nonfucosylated , mono- and biantennary N-linked structures (49.3 and 36.7%, means); fucosylated biantennary and triantennary oligosaccharides were also identified (7.3 and 6.9%).[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]]]] <br>
  '''term_in_sentence''' : The structures of the two major oligosaccharide-alditols separated by ion-exchange chromatography on a Mono Q column were investigated by means of methylation analysis, glycosidase digestion, and Smith periodate degradation, and they were assigned as typical di- and trisialylated complex-type oligosaccharide-alditols with two and three peripheral chains consisting of Gal-GlcNAc sequences , respectively.[PMID:[https://pubmed.ncbi.nlm.nih.gov/3571205 3571205]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]]]|[https://pubmed.ncbi.nlm.nih.gov/30258536 30258536]|[https://pubmed.ncbi.nlm.nih.gov/23554380 23554380]|[https://pubmed.ncbi.nlm.nih.gov/16675584 16675584]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26747427 26747427] [https://pubmed.ncbi.nlm.nih.gov/26747427 26747427]]|[https://pubmed.ncbi.nlm.nih.gov/22457527 22457527]|[https://pubmed.ncbi.nlm.nih.gov/24362443 24362443]|[https://pubmed.ncbi.nlm.nih.gov/19657637 19657637]|[https://pubmed.ncbi.nlm.nih.gov/8811881 8811881]|[https://pubmed.ncbi.nlm.nih.gov/19218011 19218011]|[https://pubmed.ncbi.nlm.nih.gov/20022111 20022111]|[https://pubmed.ncbi.nlm.nih.gov/17363544 17363544]|[https://pubmed.ncbi.nlm.nih.gov/17368483 17368483]|[https://pubmed.ncbi.nlm.nih.gov/20564614 20564614]|[https://pubmed.ncbi.nlm.nih.gov/27054024 27054024]|[https://pubmed.ncbi.nlm.nih.gov/28397880 28397880]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31490688 31490688] [https://pubmed.ncbi.nlm.nih.gov/31490688 31490688]]|[https://pubmed.ncbi.nlm.nih.gov/31860772 31860772]|[https://pubmed.ncbi.nlm.nih.gov/17012310 17012310]|[https://pubmed.ncbi.nlm.nih.gov/29633346 29633346]|[https://pubmed.ncbi.nlm.nih.gov/9442021 9442021]|[https://pubmed.ncbi.nlm.nih.gov/30350565 30350565]|[https://pubmed.ncbi.nlm.nih.gov/30296068 30296068]|[https://pubmed.ncbi.nlm.nih.gov/31800250 31800250]|[https://pubmed.ncbi.nlm.nih.gov/30021910 30021910]|[https://pubmed.ncbi.nlm.nih.gov/31133022 31133022]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29224385 29224385] [https://pubmed.ncbi.nlm.nih.gov/29224385 29224385]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28630087 28630087] [https://pubmed.ncbi.nlm.nih.gov/28630087 28630087]]|[https://pubmed.ncbi.nlm.nih.gov/26444434 26444434]|[https://pubmed.ncbi.nlm.nih.gov/31697975 31697975]|[https://pubmed.ncbi.nlm.nih.gov/30991260 30991260] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/3571205 3571205] <br>
  '''definition''' : glycans without a fucose component/monosaccharide residue. <br>
  '''definition''' : <br>
  '''term_xref''' :  <br>
  '''term_xref''' :  <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
Line 485: Line 406:




===GSD000133===
===GSD000178===
  '''term (main_entry)''' : Nonfucosylated biantennary <br>
  '''term (main_entry)''' : Trisialylated diantennary <br>
  '''glycan_dictionary_accession''' : GSD000133 <br>
  '''glycan_dictionary_accession''' : GSD000178 <br>
  '''glytoucan_accession ''' :  <br>
  '''glytoucan_accession ''' :  <br>
  '''term_in_sentence''' : Structural analysis combining methylation-mass spectrometry and 400 MHz 1H-n.m.r. spectrometry of oligosaccharide alditols released from human leucocyte lactotransferrin shows the presence of two disialylated and non-fucosylated biantennary glycans of the N-acetyl-lactosaminic type.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2390069 2390069] [https://pubmed.ncbi.nlm.nih.gov/2390069 2390069]]] <br>
  '''term_in_sentence''' : Determination of glycan primary structures and characterization of a new type of trisialylated diantennary glycan.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1997323 1997323] [https://pubmed.ncbi.nlm.nih.gov/1997323 1997323]]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2390069 2390069] [https://pubmed.ncbi.nlm.nih.gov/2390069 2390069]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]]]|[https://pubmed.ncbi.nlm.nih.gov/1375510 1375510]|[https://pubmed.ncbi.nlm.nih.gov/9101715 9101715]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/2390069 2390069] [https://pubmed.ncbi.nlm.nih.gov/2390069 2390069]]|[https://pubmed.ncbi.nlm.nih.gov/2332109 2332109] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1997323 1997323] [https://pubmed.ncbi.nlm.nih.gov/1997323 1997323]] <br>
  '''definition''' : A biantennary glycan with two GlcNAc branches linked to the core and no fucose appears. <br>
  '''definition''' : A diantennary/biantennary glycans with three sialic acid components. <br>
  '''term_xref''' :  <br>
  '''term_xref''' :  <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
Line 497: Line 418:
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453020/ Chapter 9]<br>
  '''essentials_of_glycobiology''' : <br>




===GSD000134===
===GSD000179===
  '''term (main_entry)''' : Nonfucosylated biantennary N-Linked structures <br>
  '''term (main_entry)''' : Trisialylated triantennary <br>
  '''glycan_dictionary_accession''' : GSD000134 <br>
  '''glycan_dictionary_accession''' : GSD000179 <br>
  '''glytoucan_accession ''' :  <br>
  '''glytoucan_accession ''' :  <br>
  '''term_in_sentence''' : The beta-subunit from normal pregnancy hCG contained fucosylated and nonfucosylated biantennary N-linked structures; however, mono- and triantennary oligosaccharides were also identified (4.6 and 13.7%).[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]]]] <br>
  '''term_in_sentence''' : The N-glycans are of the complex type with the core-fucosylated disialylated biantennary and trisialylated triantennary structures predominating.[PMID:8942648] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9449027 9449027] [https://pubmed.ncbi.nlm.nih.gov/9449027 9449027]]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30194503 30194503] [https://pubmed.ncbi.nlm.nih.gov/30194503 30194503]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27501865 27501865] [https://pubmed.ncbi.nlm.nih.gov/27501865 27501865]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27501865 27501865] [https://pubmed.ncbi.nlm.nih.gov/27501865 27501865]]]|[https://pubmed.ncbi.nlm.nih.gov/10998266 10998266]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20578731 20578731] [https://pubmed.ncbi.nlm.nih.gov/20578731 20578731]]|[https://pubmed.ncbi.nlm.nih.gov/17591618 17591618]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/14751029 14751029] [https://pubmed.ncbi.nlm.nih.gov/14751029 14751029]]|[https://pubmed.ncbi.nlm.nih.gov/18818422 18818422]|[https://pubmed.ncbi.nlm.nih.gov/8942648 8942648]|[https://pubmed.ncbi.nlm.nih.gov/8900952 8900952] <br>
  '''definition''' : A biantennary N-linked glycan with two GlcNAc branches linked to the core and no fucose appears. <br>
  '''definition''' : A triantennry glycan with three sialic acid components. <br>
  '''term_xref''' :  <br>
  '''term_xref''' :  <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
'''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000135===
===GSD000180===
  '''term (main_entry)''' : Nonfucosylated triantennary <br>
  '''term (main_entry)''' : VIM-2 <br>
  '''glycan_dictionary_accession''' : GSD000135 <br>
  '''glycan_dictionary_accession''' : GSD000180 <br>
  '''glytoucan_accession ''' : <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G22418PV G22418PV] <br>
  '''term_in_sentence''' : Carbohydrate structures of human alpha-fetoprotein of patients with hepatocellular carcinoma: presence of fucosylated and non-fucosylated triantennary glycans.[PMID:[https://pubmed.ncbi.nlm.nih.gov/7679920 7679920]] <br>
  '''term_in_sentence''' : Anti-SSEA-1 which binds to glycoconjugates with a Gal beta 1-4(fuc alpha 1-3)GlcNAc epitope and VIM-2 which binds to gangliosides with a NeuAc alpha 2-3GlcNAc beta-4(FUC alpha 1-3) GlcNAc beta 1-3Gal-epitope were used to determine the expression of their corresponding carbohydrate antigens in human leukocytes and leukemia cells.[PMID:[https://pubmed.ncbi.nlm.nih.gov/1690317 1690317]] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/7679920 7679920]|[https://pubmed.ncbi.nlm.nih.gov/23274891 23274891] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/27834790 27834790]|[https://pubmed.ncbi.nlm.nih.gov/31523406 31523406]|[https://pubmed.ncbi.nlm.nih.gov/29978304 29978304]|[https://pubmed.ncbi.nlm.nih.gov/29575185 29575185]|[https://pubmed.ncbi.nlm.nih.gov/27326514 27326514]|[https://pubmed.ncbi.nlm.nih.gov/29029114 29029114]|[https://pubmed.ncbi.nlm.nih.gov/32450200 32450200]|[https://pubmed.ncbi.nlm.nih.gov/29432937 29432937]|[https://pubmed.ncbi.nlm.nih.gov/31906402 31906402]|[https://pubmed.ncbi.nlm.nih.gov/28739428 28739428]|[https://pubmed.ncbi.nlm.nih.gov/29298123 29298123]|[https://pubmed.ncbi.nlm.nih.gov/30976429 30976429]|[https://pubmed.ncbi.nlm.nih.gov/29091730 29091730]|[https://pubmed.ncbi.nlm.nih.gov/27770796 27770796]|[https://pubmed.ncbi.nlm.nih.gov/31330771 31330771]|[https://pubmed.ncbi.nlm.nih.gov/31138570 31138570]|[https://pubmed.ncbi.nlm.nih.gov/27154587 27154587]|[https://pubmed.ncbi.nlm.nih.gov/31542553 31542553]|[https://pubmed.ncbi.nlm.nih.gov/30519059 30519059]|[https://pubmed.ncbi.nlm.nih.gov/30590504 30590504]|[https://pubmed.ncbi.nlm.nih.gov/25880997 25880997]|[https://pubmed.ncbi.nlm.nih.gov/27490501 27490501]|[https://pubmed.ncbi.nlm.nih.gov/29981456 29981456]|[https://pubmed.ncbi.nlm.nih.gov/28559273 28559273]|[https://pubmed.ncbi.nlm.nih.gov/28193652 28193652]|[https://pubmed.ncbi.nlm.nih.gov/26638216 26638216]|[https://pubmed.ncbi.nlm.nih.gov/25897818 25897818]|[https://pubmed.ncbi.nlm.nih.gov/26238337 26238337]|[https://pubmed.ncbi.nlm.nih.gov/19553129 19553129]|[https://pubmed.ncbi.nlm.nih.gov/29644540 29644540]|[https://pubmed.ncbi.nlm.nih.gov/26242685 26242685]|[https://pubmed.ncbi.nlm.nih.gov/28487556 28487556]|[https://pubmed.ncbi.nlm.nih.gov/32622213 32622213]|[https://pubmed.ncbi.nlm.nih.gov/30248413 30248413]|[https://pubmed.ncbi.nlm.nih.gov/24762211 24762211]|[https://pubmed.ncbi.nlm.nih.gov/11451678 11451678]|[https://pubmed.ncbi.nlm.nih.gov/33169865 33169865]|[https://pubmed.ncbi.nlm.nih.gov/11897589 11897589]|[https://pubmed.ncbi.nlm.nih.gov/31479607 31479607] <br>
  '''definition''' : A triantennary N-linked glycan with three GlcNAc branches linked to the core and no fucose appears. <br>
  '''definition''' : α-Neup5Ac-(2→3)-β-D-Galp-(1→4)-β-D-GlcpNAc-(1→3)-β-D-Galp-(1→4)-[α-L-Fucp-(1→3)]-D-GlcpNAc in which the anomeric configuration of the N-acetyl-D-glucosamine residue at the reducing end is β.[CHEBI:85946] <br>
  '''term_xref''' : <br>
  '''term_xref''' : GTC:G22418PV |GlycoEpitope:EP0019|CID:[https://pubmed.ncbi.nlm.nih.gov/91825708 91825708]|CHEBI:85946|GlycoMotif:GGM.000033 <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' : Appears in human alpha-fetoprotein (AFP).[PMID:[https://pubmed.ncbi.nlm.nih.gov/7679920 7679920]] <br>
  '''function''' : CDw65 have been shown to interact with the ELAM-1 molecule on activated endothelium.[GlycoEpitope:EP0019] <br>
  '''disease_associations''' : hepatocellular carcinoma[PMID:[https://pubmed.ncbi.nlm.nih.gov/7679920 7679920]]. <br>
  '''disease_associations''' : chronic myelogenous leukemia.[GlycoEpitope:EP0019] <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000136===
===GSD000181===
  '''term (main_entry)''' : Nonsialylated <br>
  '''term (main_entry)''' : N-acetyllactosamine (Type 1)<br>
  '''glycan_dictionary_accession''' : GSD000136 <br>
  '''glycan_dictionary_accession''' : GSD000181<br>
  '''glytoucan_accession ''' : <br>
  '''glytoucan_accession ''' : [https://glygen.org/glycan/G00056MO G00056MO]<br>
  '''term_in_sentence''' : The pattern of nonsialylated oligosaccharides was used for interpretation of the fully sialylated species using bioinformatics tools. From pooled human plasma, we find 90, 101, and 64 different glycan compositions for genetic variants ORM1*F1, ORM1*S, and ORM2, respectively. Glycan structures carry dominantly between 15 and 16 sialic acids indicating an almost complete termination of all antenae with sialic acid.[PMID:[https://pubmed.ncbi.nlm.nih.gov/30295034 30295034]] <br>
  '''term_in_sentence''' : The N-acetyllactosamine type 1 (LacNAc type 1, Galβ1,3GlcNAc) is a well-known precursor of several important blood group epitopes, such as Lewis A, Lewis B, or sialyl Lewis A [1], which are involved in many biological processes, e.g., fertilization [2] and pathogen adhesion [3]. [PMID:[https://pubmed.ncbi.nlm.nih.gov/28796164 28796164]]<br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/14533820 14533820]|[https://pubmed.ncbi.nlm.nih.gov/1377689 1377689]|[https://pubmed.ncbi.nlm.nih.gov/9705949 9705949]|[https://pubmed.ncbi.nlm.nih.gov/30788437 30788437]|[https://pubmed.ncbi.nlm.nih.gov/28090561 28090561]|[https://pubmed.ncbi.nlm.nih.gov/12498371 12498371]|[https://pubmed.ncbi.nlm.nih.gov/26839900 26839900]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31490688 31490688] [https://pubmed.ncbi.nlm.nih.gov/31490688 31490688]]|[https://pubmed.ncbi.nlm.nih.gov/2656426 2656426]|[https://pubmed.ncbi.nlm.nih.gov/30295034 30295034]|[https://pubmed.ncbi.nlm.nih.gov/31545048 31545048]|[https://pubmed.ncbi.nlm.nih.gov/12381155 12381155]|[https://pubmed.ncbi.nlm.nih.gov/25730103 25730103]|[https://pubmed.ncbi.nlm.nih.gov/26787879 26787879]|[https://pubmed.ncbi.nlm.nih.gov/25646460 25646460]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29224385 29224385] [https://pubmed.ncbi.nlm.nih.gov/29224385 29224385]]|[https://pubmed.ncbi.nlm.nih.gov/26063435 26063435]|[https://pubmed.ncbi.nlm.nih.gov/26954852 26954852]|[https://pubmed.ncbi.nlm.nih.gov/32889432 32889432]|[https://pubmed.ncbi.nlm.nih.gov/2825412 2825412]|[https://pubmed.ncbi.nlm.nih.gov/27504786 27504786]|[https://pubmed.ncbi.nlm.nih.gov/22431161 22431161] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/28796164 28796164]|[https://pubmed.ncbi.nlm.nih.gov/28167527 28167527]<br>
  '''definition''' : A glycan which is not sialylated. <br>
  '''definition''' : <br>
  '''term_xref''' : <br>
  '''term_xref''' : GTC:G00056MO|GlycoMotif:GGM.000005<br>
  '''synonyms''' :  <br>
  '''synonyms''' :  LacNAc type 1|Type 1 LN|Type-1 lactosamine<br>
  '''function''' : <br>
  '''function''' : <br>
  '''disease_associations''' : <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000137===
===GSD000182===
  '''term (main_entry)''' : O-fucose glycans <br>
  '''term (main_entry)''' : Polysialic acid<br>
  '''glycan_dictionary_accession''' : GSD000137 <br>
  '''glycan_dictionary_accession''' : GSD000182<br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G39294YF G39294YF] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : Recently, a number of laboratories have shown that O-fucose glycans on the epidermal growth factor (EGF)-like repeats of the Notch extracellular domain modulate Notch signaling.[PMID:[https://pubmed.ncbi.nlm.nih.gov/12417415 12417415]] <br>
  '''term_in_sentence''' : Polysialic acid (PSA) is a carbohydrate composed of a linear polymer of α2,8-linked sialic acids, primarily attached to the Neural Cell Adhesion Molecule (NCAM). [PMID:[https://pubmed.ncbi.nlm.nih.gov/36076963 36076963]]<br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/19594638 19594638]|[https://pubmed.ncbi.nlm.nih.gov/30690220 30690220]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18952191 18952191] [https://pubmed.ncbi.nlm.nih.gov/18952191 18952191]]|[https://pubmed.ncbi.nlm.nih.gov/22415200 22415200]|[https://pubmed.ncbi.nlm.nih.gov/12417415 12417415]|[https://pubmed.ncbi.nlm.nih.gov/16400812 16400812]|[https://pubmed.ncbi.nlm.nih.gov/18948267 18948267]|[https://pubmed.ncbi.nlm.nih.gov/21464368 21464368]|[https://pubmed.ncbi.nlm.nih.gov/20816394 20816394]|[https://pubmed.ncbi.nlm.nih.gov/30207383 30207383]|[https://pubmed.ncbi.nlm.nih.gov/20301232 20301232]|[https://pubmed.ncbi.nlm.nih.gov/27129198 27129198]|[https://pubmed.ncbi.nlm.nih.gov/17132502 17132502]|[https://pubmed.ncbi.nlm.nih.gov/22492969 22492969]|[https://pubmed.ncbi.nlm.nih.gov/30030822 30030822]|[https://pubmed.ncbi.nlm.nih.gov/30214079 30214079]|[https://pubmed.ncbi.nlm.nih.gov/26175457 26175457]|[https://pubmed.ncbi.nlm.nih.gov/25378397 25378397]|[https://pubmed.ncbi.nlm.nih.gov/18272537 18272537]|[https://pubmed.ncbi.nlm.nih.gov/28729422 28729422]|[https://pubmed.ncbi.nlm.nih.gov/11524432 11524432]|[https://pubmed.ncbi.nlm.nih.gov/31722217 31722217]|[https://pubmed.ncbi.nlm.nih.gov/23045360 23045360]|[https://pubmed.ncbi.nlm.nih.gov/24803430 24803430]|[https://pubmed.ncbi.nlm.nih.gov/28876865 28876865]|[https://pubmed.ncbi.nlm.nih.gov/25700513 25700513]|[https://pubmed.ncbi.nlm.nih.gov/32518939 32518939]|[https://pubmed.ncbi.nlm.nih.gov/30523691 30523691]|[https://pubmed.ncbi.nlm.nih.gov/18227520 18227520]|[https://pubmed.ncbi.nlm.nih.gov/20816217 20816217]|[https://pubmed.ncbi.nlm.nih.gov/24909690 24909690]|[https://pubmed.ncbi.nlm.nih.gov/17964136 17964136]|[https://pubmed.ncbi.nlm.nih.gov/12036964 12036964]|[https://pubmed.ncbi.nlm.nih.gov/27268051 27268051]|[https://pubmed.ncbi.nlm.nih.gov/15653671 15653671]|[https://pubmed.ncbi.nlm.nih.gov/19948734 19948734]|[https://pubmed.ncbi.nlm.nih.gov/31590629 31590629]|[https://pubmed.ncbi.nlm.nih.gov/32201074 32201074]|[https://pubmed.ncbi.nlm.nih.gov/15189151 15189151]|[https://pubmed.ncbi.nlm.nih.gov/17263732 17263732]|[https://pubmed.ncbi.nlm.nih.gov/32913123 32913123]|[https://pubmed.ncbi.nlm.nih.gov/12909620 12909620]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28785176 28785176] [https://pubmed.ncbi.nlm.nih.gov/28785176 28785176]]|[https://pubmed.ncbi.nlm.nih.gov/17132500 17132500]|[https://pubmed.ncbi.nlm.nih.gov/22949680 22949680]|[https://pubmed.ncbi.nlm.nih.gov/25053492 25053492]|[https://pubmed.ncbi.nlm.nih.gov/28939751 28939751] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/36076963 36076963]|[https://pubmed.ncbi.nlm.nih.gov/35222358 35222358]<br>
  '''definition''' : Form of glycosylation where the protein is modified by a fucose residue and can be extended futher to form a tetrasaccharide in certain cases. alpha-linked o-fucose have a consensus motif of C2X4(s/T)C3 where C2 and C3 are conserved cysteines number 2 and 3 respectively of the EGFR like repeats. [Essentials of Glycobiology:[https://www.ncbi.nlm.nih.gov/books/NBK453017/ Chapter13]]<br>
'''definition''' : <br>
  '''term_xref''' : GTC:G39294YF|GlycoEpitope:EP0005  <br>
'''term_xref''' : GlycoMotif:GGM.000252 <br>
  '''synonyms''' :  <br>
'''synonyms''' : polySia|PSA<br>
  '''function''' : modification of Notch signaling.[GlycoEpitope:EP0005] <br>
'''function''' : <br>
  '''disease_associations''' : <br>
'''disease_associations''' : <br>
'''wikipedia''' : <br>
'''essentials_of_glycobiology''' : <br>
 
 
===GSD000183===
'''term (main_entry)''' : Hyaluronan<br>
'''glycan_dictionary_accession''' : GSD000183<br>
'''glytoucan_accession ''' : [https://glygen.org/glycan/G29086KO G29086KO]<br>
'''term_in_sentence''' : Hyaluronan (HA) comprises a major component of the extracellular matrix (ECM) in vertebrate connective tissues and is abundant in the cartilage, skin, brain, vitreous body, umbilical cord, and synovial fluid. [PMID:[https://pubmed.ncbi.nlm.nih.gov/33171800 33171800]]<br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/33171800 33171800]|[https://pubmed.ncbi.nlm.nih.gov/34209222 34209222]<br>
  '''definition''' : <br>
  '''term_xref''' : GTC:[https://glygen.org/glycan/G29086KO G29086KO]<br>
  '''synonyms''' :  HA<br>
  '''function''' : <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000138===
===GSD000184===
  '''term (main_entry)''' : O-GlcNAc <br>
  '''term (main_entry)''' : Chondroitin sulfate/dermatan sulfate<br>
  '''glycan_dictionary_accession''' : GSD000138 <br>
  '''glycan_dictionary_accession''' : GSD000184<br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G49108TO G49108TO] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : A better understanding of the mechanisms of OGT/OGA action would enable us to derive therapeutic benefits of resetting cellular O-GlcNAc levels within an optimal range.[PMID:[https://pubmed.ncbi.nlm.nih.gov/30464755 30464755]] <br>
  '''term_in_sentence''' : Heparan sulfate (HS) and chondroitin sulfate/dermatan sulfate (CS/DS) proteoglycans are heavily glycosylated proteins, crucial for animal development and homeostasis. [PMID:[https://pubmed.ncbi.nlm.nih.gov/35192612 35192612]]<br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/30464755 30464755]|[https://pubmed.ncbi.nlm.nih.gov/29049853 29049853]|[https://pubmed.ncbi.nlm.nih.gov/29594839 29594839]|[https://pubmed.ncbi.nlm.nih.gov/31654859 31654859]|[https://pubmed.ncbi.nlm.nih.gov/29404877 29404877]|[https://pubmed.ncbi.nlm.nih.gov/30105004 30105004]|[https://pubmed.ncbi.nlm.nih.gov/30669087 30669087]|[https://pubmed.ncbi.nlm.nih.gov/29790000 29790000]|[https://pubmed.ncbi.nlm.nih.gov/28408483 28408483]|[https://pubmed.ncbi.nlm.nih.gov/26862193 26862193]|[https://pubmed.ncbi.nlm.nih.gov/30523150 30523150]|[https://pubmed.ncbi.nlm.nih.gov/30037904 30037904]|[https://pubmed.ncbi.nlm.nih.gov/28408480 28408480]|[https://pubmed.ncbi.nlm.nih.gov/29352075 29352075]|[https://pubmed.ncbi.nlm.nih.gov/29456783 29456783]|[https://pubmed.ncbi.nlm.nih.gov/29577901 29577901]|[https://pubmed.ncbi.nlm.nih.gov/29223644 29223644]|[https://pubmed.ncbi.nlm.nih.gov/28638491 28638491]|[https://pubmed.ncbi.nlm.nih.gov/30221662 30221662]|[https://pubmed.ncbi.nlm.nih.gov/29904918 29904918]|[https://pubmed.ncbi.nlm.nih.gov/32155042 32155042]|[https://pubmed.ncbi.nlm.nih.gov/30298013 30298013]|[https://pubmed.ncbi.nlm.nih.gov/31630803 31630803]|[https://pubmed.ncbi.nlm.nih.gov/31847126 31847126]|[https://pubmed.ncbi.nlm.nih.gov/29784830 29784830]|[https://pubmed.ncbi.nlm.nih.gov/30181664 30181664]|[https://pubmed.ncbi.nlm.nih.gov/28768194 28768194]|[https://pubmed.ncbi.nlm.nih.gov/30134155 30134155]|[https://pubmed.ncbi.nlm.nih.gov/25336654 25336654]|[https://pubmed.ncbi.nlm.nih.gov/30356792 30356792]|[https://pubmed.ncbi.nlm.nih.gov/30199580 30199580]|[https://pubmed.ncbi.nlm.nih.gov/32329777 32329777]|[https://pubmed.ncbi.nlm.nih.gov/28408494 28408494]|[https://pubmed.ncbi.nlm.nih.gov/29774032 29774032]|[https://pubmed.ncbi.nlm.nih.gov/29044951 29044951]|[https://pubmed.ncbi.nlm.nih.gov/23836420 23836420]|[https://pubmed.ncbi.nlm.nih.gov/20301273 20301273]|[https://pubmed.ncbi.nlm.nih.gov/29772801 29772801]|[https://pubmed.ncbi.nlm.nih.gov/28922739 28922739]|[https://pubmed.ncbi.nlm.nih.gov/30100348 30100348]|[https://pubmed.ncbi.nlm.nih.gov/30793403 30793403]|[https://pubmed.ncbi.nlm.nih.gov/30657688 30657688]|[https://pubmed.ncbi.nlm.nih.gov/31237748 31237748]|[https://pubmed.ncbi.nlm.nih.gov/29756380 29756380]|[https://pubmed.ncbi.nlm.nih.gov/29954943 29954943]|[https://pubmed.ncbi.nlm.nih.gov/30018219 30018219]|[https://pubmed.ncbi.nlm.nih.gov/32207184 32207184]|[https://pubmed.ncbi.nlm.nih.gov/25566193 25566193]|[https://pubmed.ncbi.nlm.nih.gov/30626734 30626734]|[https://pubmed.ncbi.nlm.nih.gov/24759912 24759912]| <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/35192612 35192612]|[https://pubmed.ncbi.nlm.nih.gov/35425970 35425970]<br>
  '''definition''' : Form of glycosylation which exclusively occurs in the mitochondrial, cytoplasmic or nuclear compartments of the cell where the protein is modified by a GlcNAc monosaccharide on the serine or threonine residues and is generally not modified or elongated further to form more complex structures. [Essentials of Glycobiology:[https://www.ncbi.nlm.nih.gov/books/NBK453063/ Chapter19]] <br>
  '''definition''' : <br>
  '''term_xref''' : GTC:G49108TO|GlycoEpitope:EP0004|CID:24139|HMDB:HMDB[https://pubmed.ncbi.nlm.nih.gov/0000803 0000803]  <br>
  '''term_xref''' : <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  CS/DS|chondroitin/dermatan sulfate<br>
  '''function''' : <br>
  '''function''' : <br>
  '''disease_associations''' : <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>


 
===GSD000185===
'''term (main_entry)''' : Heparan sulfate/heparin<br>
'''glycan_dictionary_accession''' : GSD000185<br>
'''glytoucan_accession ''' : <br>
'''term_in_sentence''' : Heparan sulfate (HS)/heparin is a structurally complex class of glycosaminoglycans (GAGs) that have been implicated in a wide range of biological activities. [PMID:[https://pubmed.ncbi.nlm.nih.gov/31016560 31016560]]<br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/23313092 23313092]|[https://pubmed.ncbi.nlm.nih.gov/31016560 31016560]|[https://pubmed.ncbi.nlm.nih.gov/23152789 23152789]<br>
'''definition''' : <br>
'''term_xref''' :  <br>
'''synonyms''' :  HS/heparin|heparan sufate (HS)/heparin|H/HS<br>
'''function''' : <br>
'''disease_associations''' : <br>
'''wikipedia''' :  <br>
'''essentials_of_glycobiology''' :  <br>


===GSD000139===
 
  '''term (main_entry)''' : O-linked glycans <br>
===GSD000186===
  '''glycan_dictionary_accession''' : GSD000139 <br>
[[File:G00031MO.png|thumb|G00031MO]]
  '''glytoucan_accession ''' : <br>
  '''term (main_entry)''' : Core 1<br>
  '''term_in_sentence''' : Among these, six fucosylated N-linked glycansand four O-linked glycans exhibited significantly increased expression levels in GC, while five fucosylated N-linked glycans and ten fucosylated O-linked glycans exhibited significantly decreased expression levels in GC.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29865036 29865036] [https://pubmed.ncbi.nlm.nih.gov/29865036 29865036]]] <br>
  '''glycan_dictionary_accession''' : GSD000186<br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29865036 29865036] [https://pubmed.ncbi.nlm.nih.gov/29865036 29865036]]|[https://pubmed.ncbi.nlm.nih.gov/30952424 30952424]|[https://pubmed.ncbi.nlm.nih.gov/31611643 31611643]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/19577919 19577919] [https://pubmed.ncbi.nlm.nih.gov/19577919 19577919]]|[https://pubmed.ncbi.nlm.nih.gov/32019882 32019882]|[https://pubmed.ncbi.nlm.nih.gov/19139197 19139197]|[https://pubmed.ncbi.nlm.nih.gov/26184710 26184710]|[https://pubmed.ncbi.nlm.nih.gov/11159917 11159917]|[https://pubmed.ncbi.nlm.nih.gov/21536259 21536259]|[https://pubmed.ncbi.nlm.nih.gov/25186198 25186198]|[https://pubmed.ncbi.nlm.nih.gov/19277556 19277556]|[https://pubmed.ncbi.nlm.nih.gov/22261557 22261557]|[https://pubmed.ncbi.nlm.nih.gov/24115046 24115046]|[https://pubmed.ncbi.nlm.nih.gov/18725413 18725413]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15966855 15966855] [https://pubmed.ncbi.nlm.nih.gov/15966855 15966855]]|[https://pubmed.ncbi.nlm.nih.gov/24256304 24256304]|[https://pubmed.ncbi.nlm.nih.gov/25477510 25477510]|[https://pubmed.ncbi.nlm.nih.gov/10359703 10359703]|[https://pubmed.ncbi.nlm.nih.gov/24406064 24406064]|[https://pubmed.ncbi.nlm.nih.gov/22259135 22259135]|[https://pubmed.ncbi.nlm.nih.gov/29279989 29279989]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/15966855 15966855] [https://pubmed.ncbi.nlm.nih.gov/15966855 15966855]]|[https://pubmed.ncbi.nlm.nih.gov/30619255 30619255]|[https://pubmed.ncbi.nlm.nih.gov/9673446 9673446]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31676555 31676555] [https://pubmed.ncbi.nlm.nih.gov/31676555 31676555]]|[https://pubmed.ncbi.nlm.nih.gov/28745859 28745859]|[https://pubmed.ncbi.nlm.nih.gov/28196325 28196325]|[https://pubmed.ncbi.nlm.nih.gov/27975143 27975143]|[https://pubmed.ncbi.nlm.nih.gov/30591584 30591584]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28518173 28518173] [https://pubmed.ncbi.nlm.nih.gov/28518173 28518173]]|[https://pubmed.ncbi.nlm.nih.gov/17522109 17522109]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26328495 26328495] [https://pubmed.ncbi.nlm.nih.gov/26328495 26328495]]|[https://pubmed.ncbi.nlm.nih.gov/32178593 32178593]|[https://pubmed.ncbi.nlm.nih.gov/27529638 27529638]|[https://pubmed.ncbi.nlm.nih.gov/24663386 24663386]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22474328 22474328] [https://pubmed.ncbi.nlm.nih.gov/22474328 22474328]]|[https://pubmed.ncbi.nlm.nih.gov/28096352 28096352]|[https://pubmed.ncbi.nlm.nih.gov/27496768 27496768]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18952191 18952191] [https://pubmed.ncbi.nlm.nih.gov/18952191 18952191]]|[https://pubmed.ncbi.nlm.nih.gov/11135308 11135308]|[https://pubmed.ncbi.nlm.nih.gov/24917611 24917611]|[https://pubmed.ncbi.nlm.nih.gov/11532966 11532966]|[https://pubmed.ncbi.nlm.nih.gov/22786570 22786570]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/11891229 11891229] [https://pubmed.ncbi.nlm.nih.gov/11891229 11891229]]|[https://pubmed.ncbi.nlm.nih.gov/18332077 18332077]|[https://pubmed.ncbi.nlm.nih.gov/26867212 26867212]|[https://pubmed.ncbi.nlm.nih.gov/26925665 26925665]|[https://pubmed.ncbi.nlm.nih.gov/16769205 16769205]|[https://pubmed.ncbi.nlm.nih.gov/23475718 23475718]|[https://pubmed.ncbi.nlm.nih.gov/16005634 16005634]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28785176 28785176] [https://pubmed.ncbi.nlm.nih.gov/28785176 28785176]] <br>
  '''glytoucan_accession ''' : [https://glygen.org/glycan/G00031MO G00031MO]<br>
  '''definition''' : The carbohydrate portion of a glycoprotein that has a glycan linked through the hydroxyl oxygen of serine, threonine, hydroxylysine or hydroxyproline side-chains.[CHEBI:59521] <br>
  '''term_in_sentence''' : O-glycans are initiated by the addition of GalNAc to serine or threonine (via the ppGalNAcT family of glycosyltransferases), forming the Tn antigen (GalNAcα-O-Ser/Thr), which is used to generate the core 1 structure (Galβ1,3GalNAcα-O-Ser/Thr) on which most complex and branched O-glycans are derived. [PMID:31645367]<br>
  '''term_xref''' : CHEBI:59521 <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/31645367 31645367]|[https://pubmed.ncbi.nlm.nih.gov/32297877 32297877]<br>
  '''synonyms''' :  <br>
  '''definition''' : <br>
  '''function''' : Affects several important activities like protein stability, modulation of signaling molecules and enzyme activity.[PMID:[https://pubmed.ncbi.nlm.nih.gov/9673446 9673446]] <br>
  '''term_xref''' : GTC:[https://glygen.org/glycan/G00031MO G00031MO]|GlycoMotif:GGM.001005 <br>
  '''synonyms''' :  C1G<br>
  '''function''' : <br>
  '''disease_associations''' : <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>


===GSD000140===
 
  '''term (main_entry)''' : O-linked mannose <br>
===GSD000187===
  '''glycan_dictionary_accession''' : GSD000140 <br>
[[File:G99315PE.png|thumb|G99315PE]]
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G59126YU G59126YU] <br>
  '''term (main_entry)''' : Blood group A (Type 3)<br>
  '''term_in_sentence''' : Protein O-linked mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) catalyzes the first step toward the functional matriglycan structure on alpha-dystroglycan that is responsible for binding extracellular matrix proteins and certain arenaviruses.[PMID: [https://pubmed.ncbi.nlm.nih.gov/27932460 27932460]] <br>
  '''glycan_dictionary_accession''' : GSD000187<br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/27932460 27932460]|[https://pubmed.ncbi.nlm.nih.gov/24526361 24526361]|[https://pubmed.ncbi.nlm.nih.gov/25381909 25381909]|[https://pubmed.ncbi.nlm.nih.gov/26644575 26644575]|[https://pubmed.ncbi.nlm.nih.gov/23851827 23851827]|[https://pubmed.ncbi.nlm.nih.gov/28810660 28810660]|[https://pubmed.ncbi.nlm.nih.gov/19054127 19054127]|[https://pubmed.ncbi.nlm.nih.gov/23929950 23929950]|[https://pubmed.ncbi.nlm.nih.gov/21684258 21684258]|[https://pubmed.ncbi.nlm.nih.gov/22608994 22608994]|[https://pubmed.ncbi.nlm.nih.gov/28973932 28973932]|[https://pubmed.ncbi.nlm.nih.gov/24733390 24733390]|[https://pubmed.ncbi.nlm.nih.gov/31851597 31851597]|[https://pubmed.ncbi.nlm.nih.gov/29884773 29884773]|[https://pubmed.ncbi.nlm.nih.gov/28711406 28711406]|[https://pubmed.ncbi.nlm.nih.gov/14577328 14577328]|[https://pubmed.ncbi.nlm.nih.gov/21089343 21089343]|[https://pubmed.ncbi.nlm.nih.gov/14617637 14617637]|[https://pubmed.ncbi.nlm.nih.gov/9838223 9838223]|[https://pubmed.ncbi.nlm.nih.gov/17072003 17072003]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26328495 26328495] [https://pubmed.ncbi.nlm.nih.gov/26328495 26328495]]|[https://pubmed.ncbi.nlm.nih.gov/11181560 11181560]|[https://pubmed.ncbi.nlm.nih.gov/31949166 31949166]|[https://pubmed.ncbi.nlm.nih.gov/31988979 31988979]|[https://pubmed.ncbi.nlm.nih.gov/20362685 20362685]|[https://pubmed.ncbi.nlm.nih.gov/27733679 27733679]|[https://pubmed.ncbi.nlm.nih.gov/27493216 27493216]|[https://pubmed.ncbi.nlm.nih.gov/20044576 20044576]|[https://pubmed.ncbi.nlm.nih.gov/30643095 30643095]|[https://pubmed.ncbi.nlm.nih.gov/29732660 29732660]|[https://pubmed.ncbi.nlm.nih.gov/10580142 10580142]|[https://pubmed.ncbi.nlm.nih.gov/14568618 14568618]|[https://pubmed.ncbi.nlm.nih.gov/28079948 28079948]|[https://pubmed.ncbi.nlm.nih.gov/15467391 15467391]|[https://pubmed.ncbi.nlm.nih.gov/27812179 27812179]|[https://pubmed.ncbi.nlm.nih.gov/23761899 23761899]|[https://pubmed.ncbi.nlm.nih.gov/25737452 25737452]|[https://pubmed.ncbi.nlm.nih.gov/32930586 32930586]|[https://pubmed.ncbi.nlm.nih.gov/25381372 25381372]|[https://pubmed.ncbi.nlm.nih.gov/23434682 23434682]|[https://pubmed.ncbi.nlm.nih.gov/16857188 16857188]|[https://pubmed.ncbi.nlm.nih.gov/21452199 21452199]|[https://pubmed.ncbi.nlm.nih.gov/19429925 19429925]|[https://pubmed.ncbi.nlm.nih.gov/25361541 25361541]|[https://pubmed.ncbi.nlm.nih.gov/24297939 24297939]|[https://pubmed.ncbi.nlm.nih.gov/30322079 30322079]|[https://pubmed.ncbi.nlm.nih.gov/23428289 23428289]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28427937 28427937] [https://pubmed.ncbi.nlm.nih.gov/28427937 28427937]]|[https://pubmed.ncbi.nlm.nih.gov/22746206 22746206]|[https://pubmed.ncbi.nlm.nih.gov/27533452 27533452]|[https://pubmed.ncbi.nlm.nih.gov/17502374 17502374]|[https://pubmed.ncbi.nlm.nih.gov/20816174 20816174]|[https://pubmed.ncbi.nlm.nih.gov/27496765 27496765] <br>
  '''glytoucan_accession ''' : [https://glygen.org/glycan/G99315PE G99315PE]<br>
  '''definition''' : O-linked glycans that are initiated by the addtion of a Man residue to Ser or Thr. Subsequent extension of the Man defines the O-Man core type, either M1, M2, or M3. The M1 type is initated by addition of a GlcNAc in β-linkage to the 2 position of the Man residue. M2 is initiated by addition of another GlcNAc to the 6 position of the M1 core. M3 is initiated by the addition of a GlcNAc in β-linkage to the 4 position of the Man residue. M1 and M2 type core glycans can be extended and branched with Gal, Fuc, Sialic Acid, and GlcA. The M3 core is uniquely extended by a multienzyme system to generate the matriglycan polysaccharide, a protein-specific modification found only on alpha-dystroglycan. [CHEBI:87761] <br>
  '''term_in_sentence''' : <br>
  '''term_xref''' : GlycoMotif:GGM.000055|GTC:G59126YU|CHEBI:87761|GlycoEpitope:EP0002|CID:[https://pubmed.ncbi.nlm.nih.gov/91859038 91859038] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/7800218 7800218]|[https://pubmed.ncbi.nlm.nih.gov/17998569 17998569]|[https://pubmed.ncbi.nlm.nih.gov/19756298 19756298]|[https://pubmed.ncbi.nlm.nih.gov/3191504 3191504]<br>
  '''synonyms''' : O-mannosyl glycan <br>
  '''definition''' : <br>
  '''function''' : <br>
  '''term_xref''' : GlycoMotif:GGM.000011|GTC:[https://glygen.org/glycan/G99315PE G99315PE]<br>
  '''disease_associations''' : MEB/muscle-eye-brain disease[GlycoEpitope:EP0002]|WWS/walker-warburg syndrome |muscular dystrophy[GlycoEpitope:EP0002]|neuronal migration disorder[GlycoEpitope:EP0002]|Muscle-Eye-Brain disease (MEB) and Walker-Warburg Syndrome (WWS) have mutations in genes encoding glycosyltransferases needed for O -mannosyl oligosaccharide synthesis[GlycoEpitope:EP0002]|Muscular dystrophy and neuronal migration disorder are caused by mutations in a glycosyltransferase, POMGnT1.[GlycoEpitope:EP0002] <br>
  '''synonyms''' : A type 3 antigen|blood group A type 3|A antigen (type 3)<br>
  '''function''' : <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  [https://www.ncbi.nlm.nih.gov/books/NBK579929/ Chapter 14]<br>




===GSD000141===
===GSD000188===
  '''term (main_entry)''' : P1 antigen <br>
[[File:G80722US.png|thumb|G80722US]]
  '''glycan_dictionary_accession''' : GSD000141 <br>
  '''term (main_entry)''' : 6-Sulfo Sialyl Lewis x <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G12460DL G12460DL] <br>
  '''glycan_dictionary_accession''' : GSD000188<br>
  '''term_in_sentence''' : The P1 antigen was disovered in 1927 by Landsteiner and Levine, and Pk and NOR were described in 1951 and 1982, respectively.[PMID: [https://pubmed.ncbi.nlm.nih.gov/24046920 24046920]] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G80722US G80722US] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/29622537 29622537]|[https://pubmed.ncbi.nlm.nih.gov/26773500 26773500]|[https://pubmed.ncbi.nlm.nih.gov/24046920 24046920]|[https://pubmed.ncbi.nlm.nih.gov/6207232 6207232]|[https://pubmed.ncbi.nlm.nih.gov/8550516 8550516]|[https://pubmed.ncbi.nlm.nih.gov/6609976 6609976]|[https://pubmed.ncbi.nlm.nih.gov/6375319 6375319]|817855|[https://pubmed.ncbi.nlm.nih.gov/2428855 2428855]|[https://pubmed.ncbi.nlm.nih.gov/3312011 3312011]|[https://pubmed.ncbi.nlm.nih.gov/15364312 15364312]|[https://pubmed.ncbi.nlm.nih.gov/1937801 1937801]|[https://pubmed.ncbi.nlm.nih.gov/7729906 7729906] <br>
  '''term_in_sentence''' : The cognate ligands for L-selectin possess the unusual sulfated tetrasaccharide epitope 6-sulfo sialyl Lewis x (Siaalpha2-->3Galbeta1-->4[Fucalpha1-->3][SO(3)-->6]GlcNAc).[PMID:[https://pubmed.ncbi.nlm.nih.gov/11331001 11331001]] <br>
  '''definition''' : An amino pentasaccharide consisting of α-D-galactose, β-D-galactose N-acetyl-α-D-glucosamine, β-D-galactose, and β-D-glucose residues joined in sequence with ((1→4)-, (1→4)-, (1→3)- and (1→4)-linkages, respectively.[CHEBI:68484] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/11331001 11331001]|[https://pubmed.ncbi.nlm.nih.gov/2288521 2288521]|[https://pubmed.ncbi.nlm.nih.gov/26137907 26137907]|[https://pubmed.ncbi.nlm.nih.gov/9400621 9400621]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/9556613 9556613] [https://pubmed.ncbi.nlm.nih.gov/9556613 9556613]]|[https://pubmed.ncbi.nlm.nih.gov/15972893 15972893]|[https://pubmed.ncbi.nlm.nih.gov/9015359 9015359]|[https://pubmed.ncbi.nlm.nih.gov/22691873 22691873]|[https://pubmed.ncbi.nlm.nih.gov/18652681 18652681]|[https://pubmed.ncbi.nlm.nih.gov/9722682 9722682]|[https://pubmed.ncbi.nlm.nih.gov/10435581 10435581]|[https://pubmed.ncbi.nlm.nih.gov/19359410 19359410]|[https://pubmed.ncbi.nlm.nih.gov/15228275 15228275]|[https://pubmed.ncbi.nlm.nih.gov/18250165 18250165]|[https://pubmed.ncbi.nlm.nih.gov/10536036 10536036]|[https://pubmed.ncbi.nlm.nih.gov/17944600 17944600]|[https://pubmed.ncbi.nlm.nih.gov/10460836 10460836]|[https://pubmed.ncbi.nlm.nih.gov/27993973 27993973]|[https://pubmed.ncbi.nlm.nih.gov/19149511 19149511]|[https://pubmed.ncbi.nlm.nih.gov/19150806 19150806]|[https://pubmed.ncbi.nlm.nih.gov/17172261 17172261]|[https://pubmed.ncbi.nlm.nih.gov/17142960 17142960]|[https://pubmed.ncbi.nlm.nih.gov/27956273 27956273]|[https://pubmed.ncbi.nlm.nih.gov/7578028 7578028]|[https://pubmed.ncbi.nlm.nih.gov/22260995 22260995]|[https://pubmed.ncbi.nlm.nih.gov/24519996 24519996]|[https://pubmed.ncbi.nlm.nih.gov/21596021 21596021]|[https://pubmed.ncbi.nlm.nih.gov/21982762 21982762]|[https://pubmed.ncbi.nlm.nih.gov/21775439 21775439]|[https://pubmed.ncbi.nlm.nih.gov/17334369 17334369]|[https://pubmed.ncbi.nlm.nih.gov/9710564 9710564]|[https://pubmed.ncbi.nlm.nih.gov/14593101 14593101]|[https://pubmed.ncbi.nlm.nih.gov/16227985 16227985]|[https://pubmed.ncbi.nlm.nih.gov/11895802 11895802]|[https://pubmed.ncbi.nlm.nih.gov/22750968 22750968]|[https://pubmed.ncbi.nlm.nih.gov/15157883 15157883]|[https://pubmed.ncbi.nlm.nih.gov/19067429 19067429] <br>
  '''term_xref''' : GlycoMotif:GGM.000069|GTC:G12460DL|CID:[https://pubmed.ncbi.nlm.nih.gov/71296137 71296137]|CHEBI:68484|SugarBind_Ligand:160  <br>
  '''definition''' : <br>
  '''synonyms''' : <br>
  '''term_xref''' : GlycoMotif:GGM.000027|GlycoEpitope:EP0015|CID:[https://pubmed.ncbi.nlm.nih.gov/70698321 70698321]|CHEBI:71628<br>
  '''function''' : <br>
  '''synonyms''' : 6-sulfo SLex|6-Sulfo-sialyl Lewis x|6-sulfo SLe^x <br>
  '''disease_associations''' : Shigellosis[SugarBind_Ligand:160] <br>
  '''function''' : lymphocyte homing[GlycoEpitope:EP0015]<br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453054/ Chapter 23]<br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK579916/ Chapter 34]|[https://www.ncbi.nlm.nih.gov/books/NBK579966/ Chapter 35]<br>




===GSD000142===
===GSD000189===
[[File:G51699SI.png|thumb|G51699SI]]
[[File:G89208KM.png|thumb|G89208KM]]
  '''term (main_entry)''' : Para-Forssman glycolipid <br>
  '''term (main_entry)''' : Blood group B (Type 1) - Lewis b<br>
  '''glycan_dictionary_accession''' : GSD000142 <br>
  '''glycan_dictionary_accession''' : GSD000189<br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G51699SI G51699SI] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G89208KM G89208KM] <br>
  '''term_in_sentence''' : A novel pentaglycosyl ceramide containing di-beta-N-acetylgalactos-aminyl residue (Para-Forssman glycolipid) isolated from human erythrocyte membrane. [PMID:[https://pubmed.ncbi.nlm.nih.gov/6814203 6814203]] <br>
  '''term_in_sentence''' : Ten monoclonal antibodies and one lectin were used to study the localization and distribution of Blood Group ABH, type 1 chain (Lewis a, Lewis b) and type 2 chain (H-2, Y) antigens in 22 cases of normal uterine cervix, with known ABO and Lewis phenotype and secretor status. [PMID:[https://pubmed.ncbi.nlm.nih.gov/2247887 2247887]]<br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/6814203 6814203] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/2247887 2247887]|[https://pubmed.ncbi.nlm.nih.gov/19756298 19756298]|[https://pubmed.ncbi.nlm.nih.gov/30831115 30831115]<br>
  '''definition''' : GalNAcβ1→3GalNAcβ1→3Galα1→4Galβ1→4Glcβ1→1Cer [https://doi.org/10.1016/S0040-4039(01)93814-6<nowiki>] </nowiki><br>
  '''definition''' : <br>
  '''term_xref''' : GlycoMotif:GGM.000085|GTC:G51699SI|CID:[https://pubmed.ncbi.nlm.nih.gov/56836111 56836111]|KEGG:G00096|SugarBind_Ligand:19|CHEBI:151565 <br>
  '''term_xref''' : GlycoMotif:GGM.000046<br>
  '''synonyms''' :  <br>
  '''synonyms''' :  Blood Group B, type 1 chain (Lewis b)|B-Leb|B-Le^b<br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' : Actinomycosis[SugarBind_Ligand:19] <br>
  '''disease_associations''' : <br>
  '''wikipedia''' : https://en.wikipedia.org/wiki/P1PK_blood_group_system <br>
  '''wikipedia''' : <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>




===GSD000143===
===GSD000190===
  '''term (main_entry)''' : Paragloboside <br>
[[File:G97501MA.png|thumb|G97501MA]]
  '''glycan_dictionary_accession''' : GSD000143 <br>
  '''term (main_entry)''' : Blood group A (Type 1) - Lewis b<br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G58896AZ G58896AZ] <br>
  '''glycan_dictionary_accession''' : GSD000190<br>
  '''term_in_sentence''' : Galactosyltransferase activities in sera of cancer patients were determined by assaying the formation of paragloboside from UDP-galactose and lactotriaosylceramide immobilized on microtiter plates by means of the enzyme-linked immunosorbent assay using a monoclonal antibody, H-11, directed to paragloboside. [PMID: [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1551117 1551117] [https://pubmed.ncbi.nlm.nih.gov/1551117 1551117]]] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G97501MA G97501MA] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/3345524 3345524]|850070|[https://pubmed.ncbi.nlm.nih.gov/10569746 10569746]|[https://pubmed.ncbi.nlm.nih.gov/30624951 30624951]|[https://pubmed.ncbi.nlm.nih.gov/29438961 29438961]|[https://pubmed.ncbi.nlm.nih.gov/6816790 6816790]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/1551117 1551117] [https://pubmed.ncbi.nlm.nih.gov/1551117 1551117]]|[https://pubmed.ncbi.nlm.nih.gov/6865961 6865961]|[https://pubmed.ncbi.nlm.nih.gov/25039255 25039255] <br>
  '''term_in_sentence''' : Ten monoclonal antibodies and one lectin were used to study the localization and distribution of Blood Group ABH, type 1 chain (Lewis a, Lewis b) and type 2 chain (H-2, Y) antigens in 22 cases of normal uterine cervix, with known ABO and Lewis phenotype and secretor status.[PMID:[https://pubmed.ncbi.nlm.nih.gov/2247887 2247887]]<br>
  '''definition''' : α-Neup5Ac-(2→3)-β-D-Galp-(1→3)-D-GalpNAc in which the configuration at the GalNAc anomeric carbon is α.[CHEBI:65257] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/2247887 2247887]|[https://pubmed.ncbi.nlm.nih.gov/19756298 19756298]|[https://pubmed.ncbi.nlm.nih.gov/4041428 4041428]|[https://pubmed.ncbi.nlm.nih.gov/5686860 5686860]<br>
  '''term_xref''' : GlycoMotif:GGM.000077|GTC:G58896AZ|CID:[https://pubmed.ncbi.nlm.nih.gov/21670519 21670519]|CHEBI:65257|GlycoEpitope:EP0075|SugarBind_Ligand:15 <br>
  '''definition''' : A branched amino pentasaccharide consisting of the linear trisaccharide N-acetyl-α-D-galactosaminyl-(1→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosamine having α-L-fucosyl residues attached at position 2 of the galactose and position 4 of the glucosamine. Corresponds to a partial structure of blood group A type 1 oligosaccharide.[CHEBI:62988]<br>
  '''synonyms''' :  <br>
  '''term_xref''' : GlycoMotif:GGM.000047|CID:[https://pubmed.ncbi.nlm.nih.gov/53477630 53477630]|CHEBI:62988|GlycoEpitope:EP0260<br>
  '''synonyms''' :  Blood Group A Type 1 (difucosyl)|ALe^b|A-Leb|A-Le^b|A Lewis b<br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' : Pharyngitis[SugarBind_Ligand:15]|Tracheobronchitis[SugarBind_Ligand:15]|Gonorrhea[SugarBind_Ligand:15]|Actinomycosis[SugarBind_Ligand:15]|Diarrhea[SugarBind_Ligand:15]|Hemorrhagic colitis[SugarBind_Ligand:15]|Chronic gastritis[SugarBind_Ligand:15]|Peptic ulcers[SugarBind_Ligand:15]|Gastric cancer[SugarBind_Ligand:15]|Influenza[SugarBind_Ligand:15] <br>
  '''disease_associations''' : <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
  '''essentials_of_glycobiology''' : <br>




===GSD000144===
===GSD000191===
  '''term (main_entry)''' : Paucimannose <br>
[[File:G18464VS.png|thumb|G18464VS]]
  '''glycan_dictionary_accession''' : GSD000144 <br>
  '''term (main_entry)''' : Sulfated LacdiNAc<br>
  '''glytoucan_accession ''' : <br>
  '''glycan_dictionary_accession''' : GSD000191<br>
  '''term_in_sentence''' : The galactosylation of core fucose (GalFuc epitope) in paucimannose and complex-type N-glycans is characteristic of protostome organisms, including flatworms (planarians).[PMID:[https://pubmed.ncbi.nlm.nih.gov/29475940 29475940]] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G18464VS G18464VS] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/29475940 29475940]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29803109 29803109] [https://pubmed.ncbi.nlm.nih.gov/29803109 29803109]]|[https://pubmed.ncbi.nlm.nih.gov/12603202 12603202]|[https://pubmed.ncbi.nlm.nih.gov/31817246 31817246]|[https://pubmed.ncbi.nlm.nih.gov/31719144 31719144]|[https://pubmed.ncbi.nlm.nih.gov/21057214 21057214]|[https://pubmed.ncbi.nlm.nih.gov/31932305 31932305]|[https://pubmed.ncbi.nlm.nih.gov/17132514 17132514]|[https://pubmed.ncbi.nlm.nih.gov/30382146 30382146]|[https://pubmed.ncbi.nlm.nih.gov/27731363 27731363]|[https://pubmed.ncbi.nlm.nih.gov/31325506 31325506]|[https://pubmed.ncbi.nlm.nih.gov/25746926 25746926]|[https://pubmed.ncbi.nlm.nih.gov/26513758 26513758]|[https://pubmed.ncbi.nlm.nih.gov/16522637 16522637]|[https://pubmed.ncbi.nlm.nih.gov/21169367 21169367]|[https://pubmed.ncbi.nlm.nih.gov/25190359 25190359]|[https://pubmed.ncbi.nlm.nih.gov/27928741 27928741]|[https://pubmed.ncbi.nlm.nih.gov/22496646 22496646]|[https://pubmed.ncbi.nlm.nih.gov/27384337 27384337]|[https://pubmed.ncbi.nlm.nih.gov/16897177 16897177]|[https://pubmed.ncbi.nlm.nih.gov/15228383 15228383]|[https://pubmed.ncbi.nlm.nih.gov/27379103 27379103]|[https://pubmed.ncbi.nlm.nih.gov/27189951 27189951]|[https://pubmed.ncbi.nlm.nih.gov/23475714 23475714]|[https://pubmed.ncbi.nlm.nih.gov/24907509 24907509]|[https://pubmed.ncbi.nlm.nih.gov/20558211 20558211]|[https://pubmed.ncbi.nlm.nih.gov/28060516 28060516]|[https://pubmed.ncbi.nlm.nih.gov/20441997 20441997]|[https://pubmed.ncbi.nlm.nih.gov/27720757 27720757]|[https://pubmed.ncbi.nlm.nih.gov/28817611 28817611]|[https://pubmed.ncbi.nlm.nih.gov/24550396 24550396]|[https://pubmed.ncbi.nlm.nih.gov/19494052 19494052]|[https://pubmed.ncbi.nlm.nih.gov/19515361 19515361]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28630087 28630087] [https://pubmed.ncbi.nlm.nih.gov/28630087 28630087]]|[https://pubmed.ncbi.nlm.nih.gov/31320997 31320997]|[https://pubmed.ncbi.nlm.nih.gov/30651366 30651366]|[https://pubmed.ncbi.nlm.nih.gov/30253927 30253927]|[https://pubmed.ncbi.nlm.nih.gov/25922361 25922361]|[https://pubmed.ncbi.nlm.nih.gov/31655162 31655162]|[https://pubmed.ncbi.nlm.nih.gov/18056652 18056652]|[https://pubmed.ncbi.nlm.nih.gov/24467287 24467287]|[https://pubmed.ncbi.nlm.nih.gov/32367383 32367383] <br>
  '''term_in_sentence''' : The mRNA expression of the enzymes related to the formation of sulfated LacdiNAc:β(1,4)-N-acetylgalactosaminyltransferases 3 (B4GALNT3) and 4 (B4GALNT4), carbohydrate sulfotransferases 8 (CHST8) and 9 (CHST9); and β(1,4)-galactosyltransferase 1 (B4GALT1) in these cells was confirmed by RT-PCR (Fig. S4).[PMID:[https://pubmed.ncbi.nlm.nih.gov/31558607 31558607]]<br>
  '''definition''' : Any N-linked glycan derivative with composition Man1-4Fuc0-1 GlcNAc2, in which the chitobiose core (GlcNAc2) is intact. Found in relatively large amounts in invertebrates and plants, they are formed by removal of the non-reducing terminal GlcNAc (\added by GlcNAcT1) from GlcNAcMan3-5GlcNAc2 by a Golgi hexosaminidase and subsequent removal of Man residues by Golgi mannosidases. Pauscimannose glycans have also been detected in vertebrates.[CHEBI:144386] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/31558607 31558607]|[https://pubmed.ncbi.nlm.nih.gov/27318476 27318476]|[https://pubmed.ncbi.nlm.nih.gov/19756298 19756298]|[https://pubmed.ncbi.nlm.nih.gov/11279168 11279168]|[https://pubmed.ncbi.nlm.nih.gov/26688390 26688390]<br>
  '''term_xref''' : CHEBI:144386 <br>
  '''definition''' : <br>
  '''synonyms''' :  <br>
  '''term_xref''' : GlycoMotif:GGM.000049<br>
  '''synonyms''' :  4'-O-sulfated LacdiNAc|4'-sulfated LDN|sulfated LDN<br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
Line 665: Line 621:




===GSD000145===
===GSD000192===
  '''term (main_entry)''' : Sd(A)/Cad <br>
[[File:G55583HW.png|thumb|G55583HW]]
  '''glycan_dictionary_accession''' : GSD000145 <br>
  '''term (main_entry)''' : Sialylated LacdiNAc<br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G41052GC G41052GC] <br>
  '''glycan_dictionary_accession''' : GSD000192<br>
  '''term_in_sentence''' : The expanding roles of the Sd(a)/Cad carbohydrate antigen and its cognate glycosyltransferase B4GALNT2.[PMID:[https://pubmed.ncbi.nlm.nih.gov/24112972 24112972]] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G55583HW G55583HW] <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/24112972 24112972]|[https://pubmed.ncbi.nlm.nih.gov/11577689 11577689]|[https://pubmed.ncbi.nlm.nih.gov/30067891 30067891]|[https://pubmed.ncbi.nlm.nih.gov/15361072 15361072] <br>
  '''term_in_sentence''' : The major non-reducing epitopes in the complex-type glycans are: Gal beta 1-4GlcNAc (lacNAc), GalNAc beta 1-4GlcNAc (lacdiNAc), NeuAc alpha 2-6Gal beta 1-4GlcNAc (sialylated lacNAc), NeuAc alpha 2-6Gal beta 1-4GlcNAc (sialylated lacdiNAc), Gal beta 1-4(Fuc alpha 1-3)GlcNAc (Lewisx), and GalNAc beta 1-4(Fuc alpha 1-3)GlcNAc (lacdiNAc analogue of Lewisx).[PMID:[https://pubmed.ncbi.nlm.nih.gov/7592613 7592613]]<br>
  '''definition''' : A branched amino tetrasaccharide comprised of a trisaccharide chain of N-acetyl-α-neuraminic acid, β-D-galactose and N-acetyl-β-D-glucosamine residues linked sequentially (2→3) and (1→4), to the galactose residue of which is also linked (1→4) an N-acetyl-β-L-galactosamine residue.
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/7592613 7592613]|[https://pubmed.ncbi.nlm.nih.gov/34192302 34192302]|[https://pubmed.ncbi.nlm.nih.gov/19756298 19756298]|[https://pubmed.ncbi.nlm.nih.gov/16286643 16286643]<br>
  [CHEBI:71561] <br>
  '''definition''' :  <br>
  '''term_xref''' : GlycoMotif:GGM.000051|GTC:G41052GC|CID:[https://pubmed.ncbi.nlm.nih.gov/70698375 70698375]|CHEBI:71561  <br>
  '''term_xref''' : GlycoMotif:GGM.000050<br>
  '''synonyms''' : Sd^a /Cad <br>
  '''synonyms''' : sialylated-LacdiNAc|Sialylated LDN<br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453020/ Chapter 9] <br>
  '''essentials_of_glycobiology''' : <br>




===GSD000146===
==Retired Terms (by Term Name)==
  '''term (main_entry)''' : SDlex <br>
===A2=== 
  '''glycan_dictionary_accession''' : GSD000146 <br>
[[File:G62735WZ.png|thumb|G62735WZ]]
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G19619KS G19619KS] <br>
  '''term (main_entry)''' : A2 <br>
  '''term_in_sentence''' : Hepatic expression of sialylated difucosyl Lex antigen (SDLex, NeuAc alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc beta 1-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc beta 1-) was studied with monoclonal antibody FH6, which defines this structure.[PMID: [https://pubmed.ncbi.nlm.nih.gov/3341453 3341453]] <br>
  '''glycan_dictionary_accession''' : GSD000015 <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/30226570 30226570]|[https://pubmed.ncbi.nlm.nih.gov/3341453 3341453]|[https://pubmed.ncbi.nlm.nih.gov/12725333 12725333] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G62735WZ G62735WZ] <br>
  '''definition''' : (2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6S)-5-acetamido-6-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-5-acetamido-6-hydroxy-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-(hydroxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.[CHEBI:148203] <br>
  '''term_in_sentence''' : Landsteiner ABO system of blood groups is most important for transfusion medicine and has subtypes of A Antigen, A1 and A2, upon which further groups of A and AB have been classified.[PMID:[https://pubmed.ncbi.nlm.nih.gov/28658771 28658771]] <br>
  '''term_xref''' : GlycoMotif:GGM.000032|GTC:G19619KS|CID:[https://pubmed.ncbi.nlm.nih.gov/91856705 91856705]|CHEBI:148203  <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/29000000 29000000]|[https://pubmed.ncbi.nlm.nih.gov/28658771 28658771] <br>
  '''synonyms''' : Sdlex|SDLe^x|SDLex <br>
  '''definition''' : <br>
  '''term_xref''' : GlycoMotif:GGM.000041|GTC:G62735WZ|CID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/91852328 91852328] [https://pubmed.ncbi.nlm.nih.gov/91852328 91852328]] <br>
  '''synonyms''' : <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
  '''essentials_of_glycobiology''' : <br>
'''date retired''' : 01/27/2023 <br>
'''reason for retirement''' : Duplicated entry. See [https://wiki.glygen.org/index.php/Glycan_structure_dictionary#GD000032 GSD000032]. <br>




===GSD000147===
===Chitin===
  '''term (main_entry)''' : Seminolipid <br>
  '''term (main_entry)''' : Chitin (This term has been retired.)<br>
  '''glycan_dictionary_accession''' : GSD000147 <br>
  '''glycan_dictionary_accession''' : GSD000042 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G72548RZ G72548RZ] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : A concise total synthesis of seminolipid, a sulfoglycolipid, has been achieved; key features include regioselective, tin-free sulfation of allyl β-d-galactopyranoside using 2,6-bis(trifluoromethyl)phenylboronic acid as protective reagent, stereoselective epoxidation, and site-selective acylation. [PMID: [https://pubmed.ncbi.nlm.nih.gov/31353379 31353379]] <br>
  '''term_in_sentence''' : In this review, we will focus on the prevalence and structural function of chitin in bacteria, fungi, and protists, with a particular focus on the evolution of chitin synthases and the function of chitin oligosaccharides as a signaling molecule in symbiosis and immunity[PMID: 31102241] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/31353379 31353379]|[https://pubmed.ncbi.nlm.nih.gov/31736776 31736776]|[https://pubmed.ncbi.nlm.nih.gov/12810822 12810822]|[https://pubmed.ncbi.nlm.nih.gov/19582571 19582571]|[https://pubmed.ncbi.nlm.nih.gov/19542524 19542524]|[https://pubmed.ncbi.nlm.nih.gov/20670037 20670037]|[https://pubmed.ncbi.nlm.nih.gov/15659616 15659616]|[https://pubmed.ncbi.nlm.nih.gov/20817833 20817833]|870059|[https://pubmed.ncbi.nlm.nih.gov/10801776 10801776]|[https://pubmed.ncbi.nlm.nih.gov/21965315 21965315]|[https://pubmed.ncbi.nlm.nih.gov/8095813 8095813]|[https://pubmed.ncbi.nlm.nih.gov/1280685 1280685]|[https://pubmed.ncbi.nlm.nih.gov/4690236 4690236]|[https://pubmed.ncbi.nlm.nih.gov/34199863 34199863]|[https://pubmed.ncbi.nlm.nih.gov/4207869 4207869]|[https://pubmed.ncbi.nlm.nih.gov/2373957 2373957]|845131 <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25738328 25738328] [https://pubmed.ncbi.nlm.nih.gov/25738328 25738328]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31102247 31102247] [https://pubmed.ncbi.nlm.nih.gov/31102247 31102247]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26982439 26982439] [https://pubmed.ncbi.nlm.nih.gov/26982439 26982439]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31685194 31685194] [https://pubmed.ncbi.nlm.nih.gov/31685194 31685194]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29197571 29197571] [https://pubmed.ncbi.nlm.nih.gov/29197571 29197571]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29182521 29182521] [https://pubmed.ncbi.nlm.nih.gov/29182521 29182521]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25725011 25725011] [https://pubmed.ncbi.nlm.nih.gov/25725011 25725011]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27787767 27787767] [https://pubmed.ncbi.nlm.nih.gov/27787767 27787767]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21736263 21736263] [https://pubmed.ncbi.nlm.nih.gov/21736263 21736263]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25300540 25300540] [https://pubmed.ncbi.nlm.nih.gov/25300540 25300540]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30840869 30840869] [https://pubmed.ncbi.nlm.nih.gov/30840869 30840869]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25081074 25081074] [https://pubmed.ncbi.nlm.nih.gov/25081074 25081074]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28250359 28250359] [https://pubmed.ncbi.nlm.nih.gov/28250359 28250359]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29763421 29763421] [https://pubmed.ncbi.nlm.nih.gov/29763421 29763421]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29910219 29910219] [https://pubmed.ncbi.nlm.nih.gov/29910219 29910219]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20161969 20161969] [https://pubmed.ncbi.nlm.nih.gov/20161969 20161969]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32019265 32019265] [https://pubmed.ncbi.nlm.nih.gov/32019265 32019265]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30879650 30879650] [https://pubmed.ncbi.nlm.nih.gov/30879650 30879650]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12587986 12587986] [https://pubmed.ncbi.nlm.nih.gov/12587986 12587986]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29773374 29773374] [https://pubmed.ncbi.nlm.nih.gov/29773374 29773374]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31376451 31376451] [https://pubmed.ncbi.nlm.nih.gov/31376451 31376451]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10906950 10906950] [https://pubmed.ncbi.nlm.nih.gov/10906950 10906950]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26096004 26096004] [https://pubmed.ncbi.nlm.nih.gov/26096004 26096004]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25595947 25595947] [https://pubmed.ncbi.nlm.nih.gov/25595947 25595947]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29452181 29452181] [https://pubmed.ncbi.nlm.nih.gov/29452181 29452181]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24083454 24083454] [https://pubmed.ncbi.nlm.nih.gov/24083454 24083454]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10856926 10856926] [https://pubmed.ncbi.nlm.nih.gov/10856926 10856926]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22732132 22732132] [https://pubmed.ncbi.nlm.nih.gov/22732132 22732132]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18657571 18657571] [https://pubmed.ncbi.nlm.nih.gov/18657571 18657571]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29175166 29175166] [https://pubmed.ncbi.nlm.nih.gov/29175166 29175166]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28842199 28842199] [https://pubmed.ncbi.nlm.nih.gov/28842199 28842199]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27592817 27592817] [https://pubmed.ncbi.nlm.nih.gov/27592817 27592817]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27302593 27302593] [https://pubmed.ncbi.nlm.nih.gov/27302593 27302593]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27339323 27339323] [https://pubmed.ncbi.nlm.nih.gov/27339323 27339323]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12705640 12705640] [https://pubmed.ncbi.nlm.nih.gov/12705640 12705640]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31635752 31635752] [https://pubmed.ncbi.nlm.nih.gov/31635752 31635752]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31063786 31063786] [https://pubmed.ncbi.nlm.nih.gov/31063786 31063786]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31151236 31151236] [https://pubmed.ncbi.nlm.nih.gov/31151236 31151236]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25940531 25940531] [https://pubmed.ncbi.nlm.nih.gov/25940531 25940531]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26093316 26093316] [https://pubmed.ncbi.nlm.nih.gov/26093316 26093316]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28962761 28962761] [https://pubmed.ncbi.nlm.nih.gov/28962761 28962761]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28093332 28093332] [https://pubmed.ncbi.nlm.nih.gov/28093332 28093332]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30875044 30875044] [https://pubmed.ncbi.nlm.nih.gov/30875044 30875044]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27723949 27723949] [https://pubmed.ncbi.nlm.nih.gov/27723949 27723949]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28119189 28119189] [https://pubmed.ncbi.nlm.nih.gov/28119189 28119189]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30600008 30600008] [https://pubmed.ncbi.nlm.nih.gov/30600008 30600008]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25081085 25081085] [https://pubmed.ncbi.nlm.nih.gov/25081085 25081085]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]]]] <br>
  '''definition''' : <br>
  '''definition''' : An aminoglycan consisting of β-(1→4)-linked N-acetyl-D-glucosamine residues.[CHEBI:17029] <br>
  '''term_xref''' : GlycoMotif:GGM.000062|GTC:G72548RZ  <br>
  '''term_xref''' : CHEBI:17029<br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK453042/ Chapter 14]<br>
  '''essentials_of_glycobiology''' : [https://www.ncbi.nlm.nih.gov/books/NBK579931/ Chapter 26]<br>
'''date retired''' : 01/27/2023 <br>
'''reason for retirement''' : Not including linear polysaccharides to glycan structure dictionary. <br>




===GSD000148===
==Retired Terms (by Glycan Dictionary Accessions)==
  '''term (main_entry)''' : Sialopentaosylceramide <br>
===GSD000015===
  '''glycan_dictionary_accession''' : GSD000148 <br>
[[File:G62735WZ.png|thumb|G62735WZ]]
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G13224CR G13224CR] <br>
  '''term (main_entry)''' : A2 <br>
  '''term_in_sentence''' : Sialylpentaosylceramide detected with anti-GM2 monoclonal antibody. Structural characterization and complementary expression with GM2 in gastric cancer and normal gastric mucosap[PMID: [https://pubmed.ncbi.nlm.nih.gov/2139874 2139874]] <br>
  '''glycan_dictionary_accession''' : GSD000015 <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/2139874 2139874] <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G62735WZ G62735WZ] <br>
  '''definition''' : A ganglioside in which the oligosaccharide portion is composed of a pentasaccharide containing one or more sialic acid residues.[CHEBI:36542] <br>
  '''term_in_sentence''' : Landsteiner ABO system of blood groups is most important for transfusion medicine and has subtypes of A Antigen, A1 and A2, upon which further groups of A and AB have been classified.[PMID:[https://pubmed.ncbi.nlm.nih.gov/28658771 28658771]] <br>
  '''term_xref''' : GlycoMotif:GGM.000097|GTC:G13224CR|CID:[https://pubmed.ncbi.nlm.nih.gov/91859576 91859576]|CHEBI:148045|KEGG:G00883|CHEBI:36542 <br>
  '''publication''' : [https://pubmed.ncbi.nlm.nih.gov/29000000 29000000]|[https://pubmed.ncbi.nlm.nih.gov/28658771 28658771] <br>
  '''definition''' : <br>
  '''term_xref''' : GlycoMotif:GGM.000041|GTC:G62735WZ|CID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/91852328 91852328] [https://pubmed.ncbi.nlm.nih.gov/91852328 91852328]] <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
Line 724: Line 688:
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
'''date retired''' : 01/27/2023 <br>
'''reason for retirement''' : Duplicated entry. See [https://wiki.glygen.org/index.php/Glycan_structure_dictionary#GD000032 GSD000032]. <br>




===GSD000149===
===GSD000042===
  '''term (main_entry)''' : Sialosyl paragloboside <br>
  '''term (main_entry)''' : Chitin <br>
  '''glycan_dictionary_accession''' : GSD000149 <br>
  '''glycan_dictionary_accession''' : GSD000042 <br>
  '''glytoucan_accession ''' : [https://www.glygen.org/glycan/G50123ZO G50123ZO] <br>
  '''glytoucan_accession ''' : <br>
  '''term_in_sentence''' : Unlike CNS myelin, human peripheral nerve myelin has the acidic glycosphingolipids sialosyl paragloboside (SPG), sialosyl lactosaminyl paragloboside (SLPG), and sulfated glucuronyl paragloboside (SGPG).[PMID:[https://pubmed.ncbi.nlm.nih.gov/8862128 8862128]] <br>
  '''term_in_sentence''' : In this review, we will focus on the prevalence and structural function of chitin in bacteria, fungi, and protists, with a particular focus on the evolution of chitin synthases and the function of chitin oligosaccharides as a signaling molecule in symbiosis and immunity[PMID: 31102241] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/8862128 8862128]|[https://pubmed.ncbi.nlm.nih.gov/7236652 7236652]|[https://pubmed.ncbi.nlm.nih.gov/2370108 2370108]|[https://pubmed.ncbi.nlm.nih.gov/3133978 3133978]|[https://pubmed.ncbi.nlm.nih.gov/2905604 2905604]|[https://pubmed.ncbi.nlm.nih.gov/1749114 1749114]|[https://pubmed.ncbi.nlm.nih.gov/1573418 1573418] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25738328 25738328] [https://pubmed.ncbi.nlm.nih.gov/25738328 25738328]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31102247 31102247] [https://pubmed.ncbi.nlm.nih.gov/31102247 31102247]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26982439 26982439] [https://pubmed.ncbi.nlm.nih.gov/26982439 26982439]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31685194 31685194] [https://pubmed.ncbi.nlm.nih.gov/31685194 31685194]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29197571 29197571] [https://pubmed.ncbi.nlm.nih.gov/29197571 29197571]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29182521 29182521] [https://pubmed.ncbi.nlm.nih.gov/29182521 29182521]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25725011 25725011] [https://pubmed.ncbi.nlm.nih.gov/25725011 25725011]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27787767 27787767] [https://pubmed.ncbi.nlm.nih.gov/27787767 27787767]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21736263 21736263] [https://pubmed.ncbi.nlm.nih.gov/21736263 21736263]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25300540 25300540] [https://pubmed.ncbi.nlm.nih.gov/25300540 25300540]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30840869 30840869] [https://pubmed.ncbi.nlm.nih.gov/30840869 30840869]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25081074 25081074] [https://pubmed.ncbi.nlm.nih.gov/25081074 25081074]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28250359 28250359] [https://pubmed.ncbi.nlm.nih.gov/28250359 28250359]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29763421 29763421] [https://pubmed.ncbi.nlm.nih.gov/29763421 29763421]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29910219 29910219] [https://pubmed.ncbi.nlm.nih.gov/29910219 29910219]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/20161969 20161969] [https://pubmed.ncbi.nlm.nih.gov/20161969 20161969]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/32019265 32019265] [https://pubmed.ncbi.nlm.nih.gov/32019265 32019265]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30879650 30879650] [https://pubmed.ncbi.nlm.nih.gov/30879650 30879650]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12587986 12587986] [https://pubmed.ncbi.nlm.nih.gov/12587986 12587986]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29773374 29773374] [https://pubmed.ncbi.nlm.nih.gov/29773374 29773374]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31376451 31376451] [https://pubmed.ncbi.nlm.nih.gov/31376451 31376451]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10906950 10906950] [https://pubmed.ncbi.nlm.nih.gov/10906950 10906950]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26096004 26096004] [https://pubmed.ncbi.nlm.nih.gov/26096004 26096004]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25595947 25595947] [https://pubmed.ncbi.nlm.nih.gov/25595947 25595947]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]]]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29452181 29452181] [https://pubmed.ncbi.nlm.nih.gov/29452181 29452181]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/24083454 24083454] [https://pubmed.ncbi.nlm.nih.gov/24083454 24083454]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/10856926 10856926] [https://pubmed.ncbi.nlm.nih.gov/10856926 10856926]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/22732132 22732132] [https://pubmed.ncbi.nlm.nih.gov/22732132 22732132]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/18657571 18657571] [https://pubmed.ncbi.nlm.nih.gov/18657571 18657571]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/29175166 29175166] [https://pubmed.ncbi.nlm.nih.gov/29175166 29175166]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28842199 28842199] [https://pubmed.ncbi.nlm.nih.gov/28842199 28842199]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27592817 27592817] [https://pubmed.ncbi.nlm.nih.gov/27592817 27592817]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27302593 27302593] [https://pubmed.ncbi.nlm.nih.gov/27302593 27302593]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27339323 27339323] [https://pubmed.ncbi.nlm.nih.gov/27339323 27339323]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/12705640 12705640] [https://pubmed.ncbi.nlm.nih.gov/12705640 12705640]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31635752 31635752] [https://pubmed.ncbi.nlm.nih.gov/31635752 31635752]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31063786 31063786] [https://pubmed.ncbi.nlm.nih.gov/31063786 31063786]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/31151236 31151236] [https://pubmed.ncbi.nlm.nih.gov/31151236 31151236]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25940531 25940531] [https://pubmed.ncbi.nlm.nih.gov/25940531 25940531]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26093316 26093316] [https://pubmed.ncbi.nlm.nih.gov/26093316 26093316]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28962761 28962761] [https://pubmed.ncbi.nlm.nih.gov/28962761 28962761]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28093332 28093332] [https://pubmed.ncbi.nlm.nih.gov/28093332 28093332]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30875044 30875044] [https://pubmed.ncbi.nlm.nih.gov/30875044 30875044]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27723949 27723949] [https://pubmed.ncbi.nlm.nih.gov/27723949 27723949]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/28119189 28119189] [https://pubmed.ncbi.nlm.nih.gov/28119189 28119189]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/30600008 30600008] [https://pubmed.ncbi.nlm.nih.gov/30600008 30600008]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/25081085 25081085] [https://pubmed.ncbi.nlm.nih.gov/25081085 25081085]]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932]]]] <br>
  '''definition''' : α-Neup5Ac-(2→3)-β-D-Galp-(1→4)-D-GlcpNAc with β configuration at the anomeric position of the reducing-end N-acetyl-D-glucosamine residue.[CHEBI:71612] <br>
  '''definition''' : An aminoglycan consisting of β-(1→4)-linked N-acetyl-D-glucosamine residues.[CHEBI:17029] <br>
  '''term_xref''' : GlycoMotif:GGM.000081|GTC:G50123ZO|CID:[https://pubmed.ncbi.nlm.nih.gov/91845504 91845504]|KEGG:G01429|CHEBI:151914  <br>
  '''term_xref''' : CHEBI:17029 <br>
  '''synonyms''' :  <br>
  '''synonyms''' :  <br>
  '''function''' :  <br>
  '''function''' :  <br>
  '''disease_associations''' :  <br>
  '''disease_associations''' :  <br>
  '''wikipedia''' :  <br>
  '''wikipedia''' :  <br>
  '''essentials_of_glycobiology''' :  <br>
  '''essentials_of_glycobiology''' :  [https://www.ncbi.nlm.nih.gov/books/NBK579931/ Chapter 26]<br>
'''date retired''' : 01/27/2023 <br>
'''reason for retirement''' : Not including linear polysaccharides to glycan structure dictionary. <br>




===GSD000150===
==Submit new terms==
'''term (main_entry)''' : Sialyl Lewis a <br>
If you feel that a term is missing, you can submit a single term using the online form found at https://data.glygen.org/gsd/ . To submit multiple terms you can use GlyGen file upload https://data.glygen.org/uploads. Template for submitting terms can be found [https://docs.google.com/spreadsheets/d/19ZCAJk_LyLjXT4W-hNWCCwcyndQlGooFLoJ5qCDdxDI/edit#gid=0 here]. Contact https://www.glygen.org/contact-us/ for any questions.
'''glycan_dictionary_accession''' : GSD000150 <br>
'''glytoucan_accession ''' : [https://www.glygen.org/glycan/G00053MO G00053MO] <br>
'''term_in_sentence''' : By comparing the serum O-glycan profiles from healthy controls with those of cancer patients, we identified a marker candidate, core 1 sialyl Lewis A (NeuAcα2-3Galβ1-3(Fucα1-4)GlcNAcβ1-3Gal) (abbreviated C1SLA), whose concentration appeared to be weakly correlated with CA19-9 values.[PMID:[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26641888 26641888] [https://pubmed.ncbi.nlm.nih.gov/26641888 26641888]]] <br>
'''publication''' : [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26641888 26641888] [https://pubmed.ncbi.nlm.nih.gov/26641888 26641888]]|[https://pubmed.ncbi.nlm.nih.gov/31424423 31424423]|[https://pubmed.ncbi.nlm.nih.gov/26530370 26530370]|[https://pubmed.ncbi.nlm.nih.gov/17760270 17760270]|[https://pubmed.ncbi.nlm.nih.gov/18343410 18343410]|[https://pubmed.ncbi.nlm.nih.gov/16033091 16033091]|[https://pubmed.ncbi.nlm.nih.gov/8829184 8829184]|[https://pubmed.ncbi.nlm.nih.gov/11907351 11907351]|[https://pubmed.ncbi.nlm.nih.gov/20592391 20592391]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/26641888 26641888] [https://pubmed.ncbi.nlm.nih.gov/26641888 26641888]]|[https://pubmed.ncbi.nlm.nih.gov/24128856 24128856]|[https://pubmed.ncbi.nlm.nih.gov/30249386 30249386]|[https://pubmed.ncbi.nlm.nih.gov/10773785 10773785]|[https://pubmed.ncbi.nlm.nih.gov/16149606 16149606]|[https://pubmed.ncbi.nlm.nih.gov/10996727 10996727]|[https://pubmed.ncbi.nlm.nih.gov/10436809 10436809]|[https://pubmed.ncbi.nlm.nih.gov/10667238 10667238]|[https://pubmed.ncbi.nlm.nih.gov/7720892 7720892]|[https://pubmed.ncbi.nlm.nih.gov/7630017 7630017]|[https://pubmed.ncbi.nlm.nih.gov/10612415 10612415]|[https://pubmed.ncbi.nlm.nih.gov/9836451 9836451]|[https://pubmed.ncbi.nlm.nih.gov/12511721 12511721]|[https://pubmed.ncbi.nlm.nih.gov/22623153 22623153] <br>
'''definition''' : A sialyated version of Lewis A with a branched structure of amino tetrasaccharide consisting of a sialyl residue, linked (2→3) to a galactosyl residue that in turn is linked (1→3) to a glucosaminyl residue at the reducing end, which is also carrying a fucosyl residue at the 4-position.[CHEBI:62681] <br>
'''term_xref''' : GTC:G00053MO|GlycoEpitope:EP0008|CID:[https://pubmed.ncbi.nlm.nih.gov/53356732 53356732]|CHEBI:62681|GlycoMotif:GGM.000024 <br>
'''synonyms''' : SLea|CA19-9|CA19-9 antigen|SLe^a|Slea <br>
'''function''' : The carbohydrate determinants,Sialyl Lea and Sialyl Lex,which are frequently expressed on human cancer cells,serve as ligands for a cell adhesion molecule of the selectin family,E-selectin,which is expressed on vascular endothelial cells. These carbohydrate determinants are involved in the adhesion of cancer cells to vascular endothelium and thus contribute to hematogenous metastasis of cancer.[GlycoEpitope:EP0008] <br>
'''disease_associations''' : pancreatic adenocarcinoma[GlycoEpitope:EP0008]|hepatocellular cancer[GlycoEpitope:EP0008]|cholangiocellular cancer[GlycoEpitope:EP0008]|gastric cancer|[GlycoEpitope:EP0008]colorectal cancer[GlycoEpitope:EP0008]|ovarian cancer[GlycoEpitope:EP0008]|lung cancer[GlycoEpitope:EP0008]|breast cancer[GlycoEpitope:EP0008]|uterine cancer[GlycoEpitope:EP0008] <br>
'''wikipedia''' :  <br>
'''essentials_of_glycobiology''' :  <br>

Revision as of 15:29, 12 April 2023

GSD000151

G00054MO
term (main_entry) : Sialyl Lewis x 

glycan_dictionary_accession : GSD000151 

glytoucan_accession  : G00054MO 

term_in_sentence : As sialyl Lewis X is a lignad of the selectin family, it has been proposed that sialyl Lewis X-rich colon cancer cells metastasize to the liver by adhesion to selectins on hepatic endothelial cells.[PMID:12828079] 

publication : 12828079|[https://pubmed.ncbi.nlm.nih.gov/8940172 8940172 8940172]|10075923|19054801|[https://pubmed.ncbi.nlm.nih.gov/9642161 9642161 9642161]|31054033|15229399|29061785|16033070|10728707|9556613|[https://pubmed.ncbi.nlm.nih.gov/8940172 8940172 8940172]|9298692|18607721|22593503|25944902|[https://pubmed.ncbi.nlm.nih.gov/9642161 9642161 9642161]|15780091|20401888 

definition : A sialylated version of Lewis X antigen expressed on cell surfaces with structure alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-beta-D-GlcpNAcis α-Neup5Ac-(2→3)-β-D-Galp-(1→4)-[α-L-Fucp-(1→3)]-D-GlcpNAc in which the anomeric configuration of the reducing-end N-acetyl-beta-D-glucosamine residue is beta. It is a ligand for selectins. [MESH:[https://pubmed.ncbi.nlm.nih.gov/2030970 2030970 2030970],CHEI:71622] 

term_xref : GTC:G00054MO |GlycoEpitope:EP0012|CID:44456859|CHEBI:71622|MESH:[https://pubmed.ncbi.nlm.nih.gov/2030970 2030970 2030970]|GlycoMotif:GGM.000022  

synonyms : SLe(x)|SLe^x|SLex|Slex 

function : Sialyl Lex was shown to be a specific ligand on human leukocytes for vascular E- and P-selectins,and was shown to mediate leukocyte recruitment.[GlycoEpitope:EP0012]|The determinant is also frequently expressed on human cancer cells,and is involved in the adhesion of cancer cells to vascular endothelium and thus contribute to hematogenous metastasis of cancer.[GlycoEpitope:EP0012] 

disease_associations : colon cancer[GlycoEpitope:EP0012]|colorectal cancer[GlycoEpitope:EP0012] 

wikipedia :  

essentials_of_glycobiology :


GSD000152

term (main_entry) : Sialyl Lewis x-i 

glycan_dictionary_accession : GSD000152 

glytoucan_accession  : G06597DS 

term_in_sentence : Univariate analysis showed that survival of NSCLC patients with high (more than 100 units/ml) sialyl Lewis X-i antigen levels was significantly poorer than that of patients with low antigen levels (P = 0.0001).[PMID:9815711] 

publication : 9815711|9730796|11867833|9713476|2819663|9372327|9615762|1352835|2575680|9330526|8753037|2210805|12680155|11974864|10453898|2565704|17144590 

definition :  

term_xref : GTC:G06597DS|GlycoEpitope:EP0043|CID:91855346|CHEBI:147019 

synonyms :  

function : hematogenous metastasis[GlycoEpitope:EP0043]|the progression of inflammation[GlycoEpitope:EP0043] 

disease_associations : lung cancer[GlycoEpitope:EP0043]|ovarian cancer[GlycoEpitope:EP0043]|pancreatic adenocarcinoma[GlycoEpitope:EP0043] 

wikipedia :  

essentials_of_glycobiology :


GSD000153

term (main_entry) : Sialyl T antigen 

glycan_dictionary_accession : GSD000153 

glytoucan_accession  : G65562ZE 

term_in_sentence : The expression and functional analysis of the sialyl-T antigen in prostate cancer.[PMID:32583304] 

publication : 32583304|31897478|31719620|[https://pubmed.ncbi.nlm.nih.gov/10365852 10365852 10365852]|25727149|11523928|20407596|25464017|30864133|26391208|19811634|29796594|23725156|8905873|11192238|18275089|27037304|11949946|15604091|24118321 

definition : Alpha-Neup5Ac-(2→3)-beta-D-Galp-(1→3)-alpha-D-GalpNAc is alpha-Neup5Ac-(2→3)-beta-D-Galp-(1→3)-D-GalpNAc in which the configuration at the GalNAc anomeric carbon is alpha. It has a role as an epitope.[CHEBI:65257] 

term_xref : GlycoMotif:GGM.000013|GTC:G65562ZE|CID:44611726|CHEBI:65257

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000154

term (main_entry) : Sialylated biantennary 

glycan_dictionary_accession : GSD000154 

glytoucan_accession  :  

term_in_sentence : Simbucus nigra agglutinin or an antibody specific to sialylated lactosamine with a preference for Neu5Acalpha2-6Gal rather than Neu5Acalpha2-3Gal reduced sperm binding to oviduct isthmic cells, as did occupying putative receptors on sperm with sialylated biantennary glycans.[PMID:23115267] 

publication : 23115267|31510952|29265394|31589880|3979568|26045275|29029079|30252064 

definition : A binantennary glycan with one or two sialic acid residues as non-reducing terminal residues on one or both antennae. [RN] 

term_xref :  

synonyms : sialyl biantennary 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000155

term (main_entry) : Sialylated complex-type 

glycan_dictionary_accession : GSD000155 

glytoucan_accession  :  

term_in_sentence : By using 1H-NMR spectroscopy we were able to establish that our product contains a single N-linked biantennary , fully sialylated complex-type oligosaccharide , typical of human hepatomas.[PMID:1694115] 

publication : 1694115|15201278|30471292|30969765|11058758|28342150 

definition : Complex N-linked glycan that have added GlcNAc residues at both the α-3 and α-6 mannose sites and do not contain mannose residues apart from the core structure but with sialic acid residues. 

term_xref :  

synonyms : sialo-complex type 

function : enhance the signaling activity of soluble intercellular adhesion molecule-1 in mouse astrocytes [PMID: 15201278] Appears in IgG-Fc.[PMID:20647032 ] 

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 10


GSD000156

term (main_entry) : Sialylated tetraantennary 

glycan_dictionary_accession : GSD000156 

glytoucan_accession  :  

term_in_sentence : A small amount of sialylated tetraantennary oligosaccharide was detected.[PMID:16321355] 

publication : 16321355|[https://pubmed.ncbi.nlm.nih.gov/1940447 1940447 1940447]|[https://pubmed.ncbi.nlm.nih.gov/27501865 27501865 27501865] 

definition : A tetraantennary glycan with four GlcNAc branches linked to the core and the addition of one sialic acid residues. 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000157

term (main_entry) : Sialyl-Tn antigen 

glycan_dictionary_accession : GSD000157 

glytoucan_accession  : G36123IU 

term_in_sentence : The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-β secretion from monocytes/macrophages through the DAP12-Syk pathway.[PMID:23035012] 

publication : 23035012|29273237|[https://pubmed.ncbi.nlm.nih.gov/15770530 15770530 15770530]|31595388|26617889|1720922|15466199|10971172|14652017|8616877|1543361|16965854|21566901|9269833|9834267|24970145|[https://pubmed.ncbi.nlm.nih.gov/22367369 22367369 22367369]|[https://pubmed.ncbi.nlm.nih.gov/10778170 10778170 10778170]|30018351|28628803|[https://pubmed.ncbi.nlm.nih.gov/16149605 16149605 16149605]|32134186|28632300|11308020|[https://pubmed.ncbi.nlm.nih.gov/10365852 10365852 10365852]|17195456|23567325|11014575|2342728|8575847|1851822|11735169|20960853|7846011 

definition : N-acetyl-alpha-neuraminyl-(2→6)-N-acetyl-alpha-D-galactosamine is an N-acetyl-alpha-neuraminyl-(2→6)-N-acetyl-D-galactosamine in which the carbon bearing the anomeric hydroxy group has alpha configuration. It has a role as an epitope. It derives from a N-acetyl-alpha-D-galactosamine and a N-acetyl-alpha-neuraminic acid.[CHEBI:61818] 

term_xref : GTC:G36123IU|GlycoEpitope:EP0022|CID:51351800|CHEBI:61818  

synonyms :  

function : apoptosis of monocyte-derived dendritic cells[GlycoEpitope:EP0022]|decrease of adhesion and increase of migration[GlycoEpitope:EP0022]|increase of tumor growth[GlycoEpitope:EP0022]|associated with morphological changes, decreased growth and increased migration of MDA-MB-231 cells.[GlycoEpitope:EP0022] 

disease_associations : anaplastic meningioma[GlycoEpitope:EP0022]|Barrett's esophagus[GlycoEpitope:EP0022]|bladder cancer[GlycoEpitope:EP0022]|breast cancer[GlycoEpitope:EP0022]|colon cancer[GlycoEpitope:EP0022]|colorectal cancer[GlycoEpitope:EP0022]|erythroblastic leukemia[GlycoEpitope:EP0022]|esophageal cancer[GlycoEpitope:EP0022]|gastric cancer[GlycoEpitope:EP0022]|helicobacter pylori chronic gastritis(HpCG)[GlycoEpitope:EP0022]|liver cancer[GlycoEpitope:EP0022]|iterome cancer[GlycoEpitope:EP0022]|ovary tumor[GlycoEpitope:EP0022]|pancreas cancer[GlycoEpitope:EP0022] 

wikipedia :  

essentials_of_glycobiology : Chapter 56


GSD000158

term (main_entry) : SLex Core 2 O-glycan 

glycan_dictionary_accession : GSD000158 

glytoucan_accession  : G97345NY 

term_in_sentence : In particular, the sLeX-modified core 2 O-glycan structure C2-O-sLeX has been directly demonstrated to confer significantly higher affinity selectin binding than sLeX.[PMID:15596301] 

publication : 15596301 

definition :  

term_xref : GlycoMotif:GGM.000053|GTC:G97345NY  

synonyms : SLe^x Core 2 O-glycan 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000159

term (main_entry) : SSEA-1 

glycan_dictionary_accession : GSD000159 

glytoucan_accession  : G85497PI 

term_in_sentence : Our findings suggest that expression of SSEA-1 immunoreactivity in thyroid neoplasms was associated with more aggressive thyroid carcinomas.[PMID:27550342] 

publication : 27550342|25564944|30987116|10778174|19427293|24923741|28092949|16499901|10470652|18787210|2885312|16149609|17003364|27363517|15505339|27990704|2568298|20491542|23572256|1977666|9553168|[https://pubmed.ncbi.nlm.nih.gov/20458727 20458727 20458727]|2566639|14577357|20960856|15547746|9096265|30639212|1357195|1359630|20181261|20508065|2907526|22624699|22988836|17183690|27188587|7908065|10400391|6137429|1979260|2898921|14736812|30919971 

definition :  

term_xref : GTC:G85497PI |GlycoEpitope:EP0042|CID:91851144|CHEBI:154343  

synonyms :  

function : This determinant is specifically recognized by the antibody raised against stage-specific embryonic antigen-1 (SSEA-1)[GlycoEpitope:EP0042]. The SSEA-1 antibody requires Lex hapten carried by i-antigenic structure (e.g.,nor-nLc6Cer).[GlycoEpitope:EP0042] 

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 10


GSD000160

term (main_entry) : SSEA-3 

glycan_dictionary_accession : GSD000160 

glytoucan_accession  : G25129BT 

term_in_sentence : Glycosphingolipids (GSLs), such as the globo-series GSLs stage-specific embryonic antigen 3 (SSEA-3), SSEA-4, and Globo-H, are specifically expressed on pluripotent stem cells and cancer cells, and are known to be associated with various biological processes such as cell recognition, cell adhesion, and signal transduction.[PMID:[https://pubmed.ncbi.nlm.nih.gov/31817926 31817926 31817926]] 

publication : [https://pubmed.ncbi.nlm.nih.gov/31817926 31817926 31817926]|30271856|32684574|26677875|23175153|32525407|[https://pubmed.ncbi.nlm.nih.gov/29227830 29227830 29227830]|[https://pubmed.ncbi.nlm.nih.gov/18773292 18773292 18773292]|25561682|10837462|[https://pubmed.ncbi.nlm.nih.gov/2412924 2412924 2412924]|[https://pubmed.ncbi.nlm.nih.gov/21149348 21149348 21149348]|[https://pubmed.ncbi.nlm.nih.gov/17008424 17008424 17008424]|[https://pubmed.ncbi.nlm.nih.gov/2874662 2874662 2874662]|[https://pubmed.ncbi.nlm.nih.gov/25171543 25171543 25171543]|31304790|31642560|30484221|30525067|21161592|27325407|28170296|29637816|27318475|31346146|7648586|24236059|21964054|27456773|30558911|21559451|29312455|27549315|30599359|6141938|28883415|30733757|26041528|16643871 

definition : An amino trisaccharide consisting of β-D-galactopyranose, 2-acetamido-2-deoxy-β-D-galactopyranose and α-D-galactopyranose residues joined in sequence by (1→3) glycosidic linkages.[CHEBI:149071] 

term_xref : GTC:G25129BT|GlycoEpitope:EP0039|CID:91855781|CHEBI:149071|GlycoMotif:GGM.000079  

synonyms :  

function :  

disease_associations : embryonal carcinoma[GlycoEpitope:EP0039]|teratocarcinoma[GlycoEpitope:EP0039]|yolk sac carcinoma[GlycoEpitope:EP0039] 

wikipedia :  

essentials_of_glycobiology :


GSD000161

term (main_entry) : SSEA-4 

glycan_dictionary_accession : GSD000161 

glytoucan_accession  : G84263XI 

term_in_sentence : Glycosphingolipids (GSLs), such as the globo-series GSLs stage-specific embryonic antigen 3 (SSEA-3), SSEA-4, and Globo-H, are specifically expressed on pluripotent stem cells and cancer cells, and are known to be associated with various biological processes such as cell recognition, cell adhesion, and signal transduction.[PMID:[https://pubmed.ncbi.nlm.nih.gov/31817926 31817926 31817926]] 

publication : 27845370|[https://pubmed.ncbi.nlm.nih.gov/31817926 31817926 31817926]|26295543|[https://pubmed.ncbi.nlm.nih.gov/25171543 25171543 25171543]|25978997|30296654|25853231|24862940|31243630|28736232|22895512|24578244|29478902|23574147|23768762|27797400|[https://pubmed.ncbi.nlm.nih.gov/29227830 29227830 29227830]|[https://pubmed.ncbi.nlm.nih.gov/18773292 18773292 18773292]|25123923|22924692|22665977|23330736|31831622|31916611|[https://pubmed.ncbi.nlm.nih.gov/2412924 2412924 2412924]|16033656|24866102|[https://pubmed.ncbi.nlm.nih.gov/20458727 20458727 20458727]|[https://pubmed.ncbi.nlm.nih.gov/21149348 21149348 21149348]|26940129|[https://pubmed.ncbi.nlm.nih.gov/17008424 17008424 17008424]|[https://pubmed.ncbi.nlm.nih.gov/2874662 2874662 2874662]|23301556|27836003|19118716|24550271|32988880|22743677|20683402|17062733|23570331|30310530|31545316|23509763|24364909|18273440|28985528|22266579 

definition :  

term_xref : GTC:G84263XI|GlycoEpitope:EP0044|CID:91845478|CHEBI:154843  

synonyms :  

function :  

disease_associations : teratocarcinoma[GlycoEpitope:EP0044] 

wikipedia :  

essentials_of_glycobiology : Chapter 47


GSD000162

term (main_entry) : Sulfatide 

glycan_dictionary_accession : GSD000162 

glytoucan_accession  : G72548RZ 

term_in_sentence : In a previous study we found that sulfatide was efficient in lowering HIV-1 viral loads in SCID mice engrafted with human fetal liver/thymus tissues (SCID-hu).[PMID:23550344] 

publication : 23550344|18465098|26542149|15158666|10434709|22619219|29676479|30196830|16143863|1052451|30400820|29887538|26981544|17986152|31739035|19941861|24578319|30531843|25645724|31197846|22821828|27861899|31037952|23593400|23604989|17855742|25966258|25989600|9657940|29497057|12838515|25170267|9878314|20554435|1410493|26585924|17257892|17044925|21089387|11445552|22977233|21437360|17179664|6273571|8370675 

definition :  

term_xref : GlycoMotif:GGM.000063|GTC:G72548RZ  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 47


GSD000163

term (main_entry) : T antigen 

glycan_dictionary_accession : GSD000163 

glytoucan_accession  : G00031MO 

term_in_sentence : Tn, sTn, and T antigen neo- or over-expression occurs in many types of cancer including gastric, colon, breast, lung, esophageal, prostate, and endometrial cancer.[PMID:27679419] 

publication : 723127|19505650|31527246|28113048|25868857|26731525|22994493|3849428|25589241|[https://pubmed.ncbi.nlm.nih.gov/12709866 12709866 12709866]|26615524|26136575|19671663|18551603|11160729|22261839|30758913|[https://pubmed.ncbi.nlm.nih.gov/25681708 25681708 25681708]|29113555|24998850|1654819|28039910|29206210|32404521|10555041|26517398|2446015|2998768|3026642|18812503|6092664|2153691|8709258|3009889|15109748|[https://pubmed.ncbi.nlm.nih.gov/12709866 12709866 12709866]|31787742|27433780|26017382|24048785|26735515|9224657|26061652|29343574|[https://pubmed.ncbi.nlm.nih.gov/25681708 25681708 25681708]|23805194|26751495|22023388|15381338|8249277|3023660|25866902 

definition : An amino disaccharide composed of D-galactose and N-acetyl-α-D-galactosaminyl residues in β-(1→3) linkage.[CHEBI:61820] 

term_xref : GTC:G00031MO|GlycoEpitope:EP0020|CID:5288347|CHEBI:61820|GlycoMotif:GGM.000009 

synonyms : TF antigen 

function : accumulation Lipoprotein(a) or LDL within arterial walls in atherogenesis [GlycoEpitope:EP0020]|cancer progression (increase interaction/communication of the cells)[GlycoEpitope:EP0020]|T antigen expression in RMA lymphoma cells leads to a reduced growth of the tumor[GlycoEpitope:EP0020]|correlation with elevated Golgi pH in cancer cell (breast, colorectal cancer cells)[GlycoEpitope:EP0020]|T antigen on apical surfaces of corneal epithelial cells provide protection against rose bengal penetrance.[GlycoEpitope:EP0020]|reduction of a flexibility of the glycosidic bond and thereby favour certain glycan conformation[GlycoEpitope:EP0020]|T antigen is a target for NK cell-mediated lysis[GlycoEpitope:EP0020]|inverse relationship between T antigen expression and VWF plasma levels[GlycoEpitope:EP0020] 

disease_associations : anaplastic meningioma[GlycoEpitope:EP0020]|breast cancer[GlycoEpitope:EP0020]|colorectal cancer[GlycoEpitope:EP0020]|colon cancer[GlycoEpitope:EP0020]|esophageal cancer|gastric cancer[GlycoEpitope:EP0020]|liver cancer[GlycoEpitope:EP0020]|ovarian cancer[GlycoEpitope:EP0020]|prostate cancer[GlycoEpitope:EP0020]|bladder tumor[GlycoEpitope:EP0020]|invasive pneumococcal infection (hemolytic uremic syndrome, hemolytic anemia)[GlycoEpitope:EP0020] 

wikipedia :  

essentials_of_glycobiology : Chapter 47


GSD000164

term (main_entry) : Tetraantennary
glycan_dictionary_accession : GSD000164
glytoucan_accession  :
term_in_sentence : In contrast, myeloma IgE showed a higher abundance of triantennary and tetraantennary glycan structures and a low abundance of species with a bisecting N-acetylglucosamine.[PMID:24308486]
publication : 24308486|17951374|28880909|9177699|9760189|12322961|20129637|2492275|3402460|2361735|6525453|27730440|2551687|25365149|9751793|29875690|29479898|9134426|30943309|3546284|29888905|30624066|30537828|31110965|29311294|12852965|3015940|1907570|29137999|29359131|29858715|30295034|31829566|8381405|26929217|20662591|30612270|3089784|28186213|3427034|26763099|27354006|24991291|7496138|[https://pubmed.ncbi.nlm.nih.gov/1940447 1940447 1940447]|11114588|29031301|9448855|3979385|27722599|31126011|28002670|28991403|[https://pubmed.ncbi.nlm.nih.gov/24032650 24032650 24032650]|[https://pubmed.ncbi.nlm.nih.gov/15316281 15316281 15316281]|25154914|22490318|22430811|1463783|18803208|7881173|7697655|7240157|1768292
definition : Type of N-linked glycan in which four antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The four antennae are initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 2 GlcNAcs to the _6 Man (at the 2 and 6 positions) of the trimannosyl core. Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:Glossary]
term_xref :
synonyms :
function :
disease_associations :
wikipedia : https://www.wikidata.org/wiki/Q27104888
essentials_of_glycobiology :


GSD000165

term (main_entry) : Tetraantennary complex-type 

glycan_dictionary_accession : GSD000165 

glytoucan_accession  :  

term_in_sentence : A variety of high-mannose structures , as well as bi-, tri-, and tetraantennary complex-type carbohydrate , has been found, in relative amounts of 1-25% of the total oligosaccharides.[PMID:[https://pubmed.ncbi.nlm.nih.gov/1899031 1899031 1899031]] 

publication : [https://pubmed.ncbi.nlm.nih.gov/1899031 1899031 1899031]|8251489|8274017|[https://pubmed.ncbi.nlm.nih.gov/1899031 1899031 1899031]| 6317691|23668542| 6088518|21495009|1457971|1783599|10988252|11425798|7522229|2574992|3730425|10200178|2939068|21584695| 7524670|7682847|2930192|1726466|9881746|11068879|6704968|2302846|[https://pubmed.ncbi.nlm.nih.gov/24032650 24032650 24032650]|[https://pubmed.ncbi.nlm.nih.gov/15316281 15316281 15316281]|11051207|10220588|2813359|2174368|21755550|3571208|1929437|3681300|6581225|3364983|2902877|2297756|1315684|6830758|1998670 

definition : Type of N-linked glycan in which four antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The four antennae are initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 2 GlcNAcs to the _6 Man (at the 2 and 6 positions) of the trimannosyl core. Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues.  [Essentials of Glycobiology:Glossary]  

term_xref : https://www.sigmaaldrich.com/technical-documents/articles/biology/glycobiology/n-glycans.html 

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 10


GSD000166

term (main_entry) : Tetrasialylated diantennary 

glycan_dictionary_accession : GSD000166 

glytoucan_accession  :  

term_in_sentence : A further preparation, obtained from the most anionic DEAE-cellulose fraction (peak V) or rTf contained several tetrasialylated diantennary glycans whose precise structures remain to be established in future studies.[PMID:[https://pubmed.ncbi.nlm.nih.gov/1997323 1997323 1997323]] 

publication : [https://pubmed.ncbi.nlm.nih.gov/1997323 1997323 1997323] 

definition : A biantennary glycan with two GlcNAc branches linked to the core and the addition of four sialic acid residues. 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000167

term (main_entry) : Tn antigen 

glycan_dictionary_accession : GSD000167 

glytoucan_accession  : G57321FI 

term_in_sentence : Furthermore, we confirmed that LS174T cells (Tn-positive) transfected with wild-type Cosmc, thus expressing no Tn antigen, had down-regulation of H-Ras expression and subsequent inhibition of EMT process.[PMID:30637914] 

publication : 27679419|31938254|30637914|24643043|31225574|21259410|31742337|28514044|33014816|28708980|27432485|33050853|26045765|27542280|24411673|27760846|30115016|1410473|29802864|29669308|29251002|32541028|31019509|1582597|2981150|10842187|29638123|[https://pubmed.ncbi.nlm.nih.gov/22367369 22367369 22367369]|[https://pubmed.ncbi.nlm.nih.gov/10778170 10778170 10778170]|1510031|19372570|20641477|[https://pubmed.ncbi.nlm.nih.gov/16149605 16149605 16149605]|[https://pubmed.ncbi.nlm.nih.gov/15770530 15770530 15770530]|27856425|23814067|28068458|[https://pubmed.ncbi.nlm.nih.gov/32134186 32134186 32134186]|8174100|10571017|27453399|1727666|23740330 

definition : Tn anitigen or alpha-galnac or N-Acetylgalactosamine is an N-acetyl-D-galactosamine having alpha-configuration at the anomeric centre. It has a role as an epitope. It derives from an alpha-D-galactosamine.[CHEBI:40356,HMDB0000212] 

term_xref : GTC:G57321FI|GlycoEpitope:EP0021|CID:84265|CHEBI:40356|HMDB0000212|GlycoMotif:GGM.000008  

synonyms :  

function : lymphatic metastasis[GlycoEpitope:EP0021]|tube formation in Drosophila development[GlycoEpitope:EP0021]|modulation of malignant phenotype (gastric carcinoma cell)[GlycoEpitope:EP0021]|correlation with tumor stage, lymphatic invasion and lymph node matastasis[GlycoEpitope:EP0021] 

disease_associations : breast cancer[GlycoEpitope:EP0021]|cervical cancer[GlycoEpitope:EP0021]|colon cancer[GlycoEpitope:EP0021]|colorectal cancer[GlycoEpitope:EP0021]|fibrosarcoma[GlycoEpitope:EP0021]|gastric cancer[GlycoEpitope:EP0021]|liver cancer[GlycoEpitope:EP0021]|ovarian cancer[GlycoEpitope:EP0021]|pancreas cancer[GlycoEpitope:EP0021]|prostate cancer[GlycoEpitope:EP0021]|Tn syndorome[GlycoEpitope:EP0021]|Barrett'sesophagus[GlycoEpitope:EP0021]|Schindler/Kanzaki desease (alpha-N acetylgalactosaminidase deficiency)[GlycoEpitope:EP0021]. 

wikipedia :  

essentials_of_glycobiology :


GSD000168

term (main_entry) : Triantennary 

glycan_dictionary_accession : GSD000168 

glytoucan_accession  :  

term_in_sentence : Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.[PMID:24992960] 

publication : 24992960|27025342|29642865|29456020|26914862|26926155|26299345|28981809|18395704|2211710|23461434|18327885|15264862|22954207|9061362|16581187|26537865|[https://pubmed.ncbi.nlm.nih.gov/3979568 3979568 3979568]|28129130|7679920|8068017|7783116|3857231|20540518|1706936|2430615|8078981|2211711|6767476|3814128|2597120|7451505|8204583|20619452|10460831|1924399|6643471|31809011|30042045|2477056|7882496|2430614|[https://pubmed.ncbi.nlm.nih.gov/2551687 2551687 2551687]|2426141|2065052|28988716|31144994|26966183|29809215 

definition : Type of N-linked glycan in which three antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The three antennae can be be initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 1 GlcNAc to the _6 Man (at the 2 position) of the trimannosyl core or 1 on the _3 and 2 on the _6 Man (at the 2 and 6 positions). Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues. [Essentials of Glycobiology:Glossary] 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000169

term (main_entry) : Triantennary complex 

glycan_dictionary_accession : GSD000169 

glytoucan_accession  :  

term_in_sentence : Fucosylated biantennary complex-type and small amounts (less than 5%) of triantennary complex-type structures were identified on the glycosylated asparagine residues using sequential exoglycosidase and endoglycosidase digestions combined with matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).[PMID:9118998] 

publication : 9118998|9061362|18395704|3814128|7451505|10460831|26926155|26966183|16581187|16973123|8204583|29809215|[https://pubmed.ncbi.nlm.nih.gov/11114588 11114588 11114588]|31322324|15044389|16372382|[https://pubmed.ncbi.nlm.nih.gov/8251489 8251489 8251489]|8299583|1555586|7509658|1569060|16261636 

definition : A complex N-glycan that has three branches attached to the non-reducing terminal Man residues of the trimannosyl core.[CHEBI:156252]  Each branch is initiated with a GlcNAc and can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues.  

term_xref : CHEBI:156252 

synonyms : Triantennary complex-type 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 10


GSD000170

term (main_entry) : Triantennary N-glycans 

glycan_dictionary_accession : GSD000170 

glytoucan_accession  :  

term_in_sentence : Increased expression of the high-mannose M6N2 and NeuAc3H3N3M3N2F tri-antennary N-glycans in cholangiocarcinoma.[PMID:29399163] 

publication : 29399163|22325877|18439991|24873509|11454001 

definition : Type of N-linked glycan in which three antennae are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). The three antennae can be be initiated by addition of 2 GlcNAcs to the _3 Man (at the 2 and 4 positions) and 1 GlcNAc to the _6 Man (at the 2 position) of the trimannosyl core or 1 on the _3 and 2 on the _6 Man (at the 2 and 6 positions). Each antenna can be extended or capped with HexNAc, deoxyHex, Hex, or sialic acid residues.  [Essentials of Glycobiology:Glossary]  

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000171

term (main_entry) : Triantennary sialylated 

glycan_dictionary_accession : GSD000171 

glytoucan_accession  :  

term_in_sentence : LC-ESIMS/MS analysis revealed that both light chain and heavy chain were N-glycosylated mainly by A2S2 but also by triantennary sialylated glycans.[PMID:18642129] 

publication : 18642129|31964828|[https://pubmed.ncbi.nlm.nih.gov/3979568 3979568 3979568]|27936604|23681398|21538882|7579793|7613477|2223825|3539023|3674882 

definition : A triantennary glycan with three GlcNAc branches linked to the core and the addition of one sialic acid residues. 

term_xref :  

synonyms :  

function : Appears in human serotransferrin.[PMID: [https://pubmed.ncbi.nlm.nih.gov/3979568 3979568 3979568]] 

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000172

term (main_entry) : Triantennary trisialylated fucosylated 

glycan_dictionary_accession : GSD000172 

glytoucan_accession  :  

term_in_sentence : Diantennary monosialylated glycans and triantennary trisialylated fucosylated and non-fucosylated structures have also been identified.[PMID:17591618] 

publication : 17591618 

definition : A triantennary glycan with three GlcNAc branches linked to the core and the addition of three sialic acid residues and fucose added. 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000173

term (main_entry) : Trifucosyl Lewis b antigen 

glycan_dictionary_accession : GSD000173 

glytoucan_accession  : G74578MX 

term_in_sentence : Extended type-1 chain glycosphingolipid antigens. Isolation and characterization of trifucosyl-Leb antigen (III4V4VI2Fuc3Lc6)[PMID:1735443] 

publication : 1735443 

definition : N-[(2R,3R,4R,5S,6R)-4-[(2R,3R,4S,5S,6R)-4-[(2S,3R,4R,5S,6R)-3-Acetamido-4-[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-5-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxy-6-(hydroxymethyl)-5-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]acetamide is an amino sugar.[CHEBI:153783] 

term_xref : GlycoEpitope:EP0092|GTC:G74578MX|CID:91845957|CHEBI:153783 

synonyms : trifucosyl-Leb antigen 

function : cancer-associated antigen[GlycoEpitope: EP0092] 

disease_associations : colonic cancer[GlycoEpitope: EP0092]|endometrial cancer[GlycoEpitope: EP0092]|liver cancer[GlycoEpitope: EP0092]|pancreatic cancer[GlycoEpitope: EP0092]|rectal cancer[GlycoEpitope: EP0092] 

wikipedia :  

essentials_of_glycobiology :


GSD000174

term (main_entry) : Trifucosyl lewis y 

glycan_dictionary_accession : GSD000174 

glytoucan_accession  : G74917JX 

term_in_sentence : The third, major component, common in all eight cases, has been identified as trifucosyl Ley (lactotrifucononaosylceramide, III3FucV3FucVI2FucnLc6, Structure 2 below) based on 1H NMR spectroscopy, methylation analysis, and direct-probe electron-impact mass spectrometry.[PMID:[https://pubmed.ncbi.nlm.nih.gov/3733752 3733752 3733752]] 

publication : 3733752|2426269 

definition : A branched heptasaccharide derivative consisting of two repeating units of β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc (joined by a (1→3)-linkage) with an α-L-fucosyl residue attached at the 2-position of the galactose residue at the non-reducing end.[CHEBI:61332] 

term_xref : GlycoEpitope: EP0094|GTC:G74917JX|CID:50909806|CHEBI:61332  

synonyms : trifucosyl Ley 

function :  

disease_associations : colonic adenocarcinomia[GlycoEpitope: EP0094] 

wikipedia :  

essentials_of_glycobiology :


GSD000175

term (main_entry) : Trimannosyl core 

glycan_dictionary_accession : GSD000175 

glytoucan_accession  :  

term_in_sentence : This glycoengineered H. polymorpha strain produced glycoproteins mainly containing trimannosyl core N-glycan (Man(3)GlcNAc(2)), which is the common core backbone of various human-type N-glycans.[PMID:18320567] 

publication : 18320567|27629418|26514868|26821880|2477227|6213618|31747570|29273674|31064325|1291063|28353332|1421754|29666272|11421342|15648688|28179475|28903882|27189951|9455915|22768188|9254048|8721739|2249985|22933239|25629585|24489949|2981047|11067815|1729985|1710649|16672288|2719668|19003000|23025485|22500028|10409642|1325461|23136055|23085445|21656680|22448293|22132163|1425696|20696712|18056652|15084511|18633282|15814299 

definition : A glycan that constitutes the core structure common to all high-mannose, complex, or hybrid N-glycans. The trimannosyl core composition is Man3 GlcNAc2 and includes a chitobiose at the reducing terminal which is extended by a single b-linked Man residue. The b-linked Man is branched by two additional a-linked Man residues, one at the 3 position and one at the 6 position. 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000176

term (main_entry) : Trisialylated 

glycan_dictionary_accession : GSD000176 

glytoucan_accession  :  

term_in_sentence : Many (82.7%) were found to be tetraantennary N-acetyllactosamine-type (22.8% with one, 3.6% with two and 0.4% with three N-acetyllactosamine repeats) being tetrasialylated (41%), trisialylated (29.6%) and disialylated (12.2%) |HPAE-PAD and FACE analysis suggests that they are triantennary and trisialylated with core fucosylation.[PMID:8477709] 

publication : 6469957|18818422|18332077|21138277|9136890|10782293|19841910|20067809|14751029|8797382|16877748|19131698|20578731|24669823|22426998|[https://pubmed.ncbi.nlm.nih.gov/27501865 27501865 27501865]|2121479|24663386|32209427|32737218|33245334|26927318|30962676|28370937|30194503|26321095|30463578|31455764|31566965|31266306|29782424|31247951|30487799|2049094|1997323|10913832 

definition : A glycan with three sialic acid components. 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000177

term (main_entry) : Trisialylated complex-type oligosaccharide-alditols 

glycan_dictionary_accession : GSD000177 

glytoucan_accession  :  

term_in_sentence : The structures of the two major oligosaccharide-alditols separated by ion-exchange chromatography on a Mono Q column were investigated by means of methylation analysis, glycosidase digestion, and Smith periodate degradation, and they were assigned as typical di- and trisialylated complex-type oligosaccharide-alditols with two and three peripheral chains consisting of Gal-GlcNAc sequences , respectively.[PMID:3571205] 

publication : 3571205 

definition :  

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000178

term (main_entry) : Trisialylated diantennary 

glycan_dictionary_accession : GSD000178 

glytoucan_accession  :  

term_in_sentence : Determination of glycan primary structures and characterization of a new type of trisialylated diantennary glycan.[PMID:[https://pubmed.ncbi.nlm.nih.gov/1997323 1997323 1997323]] 

publication : [https://pubmed.ncbi.nlm.nih.gov/1997323 1997323 1997323] 

definition : A diantennary/biantennary glycans with three sialic acid components. 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000179

term (main_entry) : Trisialylated triantennary 

glycan_dictionary_accession : GSD000179 

glytoucan_accession  :  

term_in_sentence : The N-glycans are of the complex type with the core-fucosylated disialylated biantennary and trisialylated triantennary structures predominating.[PMID:8942648] 

publication : [https://pubmed.ncbi.nlm.nih.gov/30194503 30194503 30194503]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/27501865 27501865 27501865] [https://pubmed.ncbi.nlm.nih.gov/27501865 27501865 27501865]]|10998266|[https://pubmed.ncbi.nlm.nih.gov/20578731 20578731 20578731]|17591618|[https://pubmed.ncbi.nlm.nih.gov/14751029 14751029 14751029]|18818422|8942648|8900952 

definition : A triantennry glycan with three sialic acid components. 

term_xref :  

synonyms :  

function :  

disease_associations :  

essentials_of_glycobiology :


GSD000180

term (main_entry) : VIM-2 

glycan_dictionary_accession : GSD000180 

glytoucan_accession  : G22418PV 

term_in_sentence : Anti-SSEA-1 which binds to glycoconjugates with a Gal beta 1-4(fuc alpha 1-3)GlcNAc epitope and VIM-2 which binds to gangliosides with a NeuAc alpha 2-3GlcNAc beta-4(FUC alpha 1-3) GlcNAc beta 1-3Gal-epitope were used to determine the expression of their corresponding carbohydrate antigens in human leukocytes and leukemia cells.[PMID:1690317] 

publication : 27834790|31523406|29978304|29575185|27326514|29029114|32450200|29432937|31906402|28739428|29298123|30976429|29091730|27770796|31330771|31138570|27154587|31542553|30519059|30590504|25880997|27490501|29981456|28559273|28193652|26638216|25897818|26238337|19553129|29644540|26242685|28487556|32622213|30248413|24762211|11451678|33169865|11897589|31479607 

definition : α-Neup5Ac-(2→3)-β-D-Galp-(1→4)-β-D-GlcpNAc-(1→3)-β-D-Galp-(1→4)-[α-L-Fucp-(1→3)]-D-GlcpNAc in which the anomeric configuration of the N-acetyl-D-glucosamine residue at the reducing end is β.[CHEBI:85946] 

term_xref : GTC:G22418PV |GlycoEpitope:EP0019|CID:91825708|CHEBI:85946|GlycoMotif:GGM.000033 

synonyms :  

function : CDw65 have been shown to interact with the ELAM-1 molecule on activated endothelium.[GlycoEpitope:EP0019] 

disease_associations : chronic myelogenous leukemia.[GlycoEpitope:EP0019] 

wikipedia :  

essentials_of_glycobiology :


GSD000181

term (main_entry) : N-acetyllactosamine (Type 1)

glycan_dictionary_accession : GSD000181

glytoucan_accession  : G00056MO

term_in_sentence : The N-acetyllactosamine type 1 (LacNAc type 1, Galβ1,3GlcNAc) is a well-known precursor of several important blood group epitopes, such as Lewis A, Lewis B, or sialyl Lewis A [1], which are involved in many biological processes, e.g., fertilization [2] and pathogen adhesion [3]. [PMID:28796164]

publication : 28796164|28167527

definition : 

term_xref : GTC:G00056MO|GlycoMotif:GGM.000005

synonyms :  LacNAc type 1|Type 1 LN|Type-1 lactosamine

function : 

disease_associations : 

wikipedia :  

essentials_of_glycobiology :


GSD000182

term (main_entry) : Polysialic acid

glycan_dictionary_accession : GSD000182

glytoucan_accession  : 

term_in_sentence : Polysialic acid (PSA) is a carbohydrate composed of a linear polymer of α2,8-linked sialic acids, primarily attached to the Neural Cell Adhesion Molecule (NCAM). [PMID:36076963]

publication : 36076963|35222358

definition : 

term_xref : GlycoMotif:GGM.000252 

synonyms :  polySia|PSA

function : 

disease_associations : 

wikipedia :  

essentials_of_glycobiology :


GSD000183

term (main_entry) : Hyaluronan

glycan_dictionary_accession : GSD000183

glytoucan_accession  : G29086KO

term_in_sentence : Hyaluronan (HA) comprises a major component of the extracellular matrix (ECM) in vertebrate connective tissues and is abundant in the cartilage, skin, brain, vitreous body, umbilical cord, and synovial fluid. [PMID:33171800]

publication : 33171800|34209222

definition : 

term_xref : GTC:G29086KO

synonyms :  HA

function : 

disease_associations : 

wikipedia :  

essentials_of_glycobiology :


GSD000184

term (main_entry) : Chondroitin sulfate/dermatan sulfate

glycan_dictionary_accession : GSD000184

glytoucan_accession  : 

term_in_sentence : Heparan sulfate (HS) and chondroitin sulfate/dermatan sulfate (CS/DS) proteoglycans are heavily glycosylated proteins, crucial for animal development and homeostasis. [PMID:35192612]

publication : 35192612|35425970

definition : 

term_xref : 

synonyms :  CS/DS|chondroitin/dermatan sulfate

function : 

disease_associations : 

wikipedia :  

essentials_of_glycobiology :


GSD000185

term (main_entry) : Heparan sulfate/heparin

glycan_dictionary_accession : GSD000185

glytoucan_accession  : 

term_in_sentence : Heparan sulfate (HS)/heparin is a structurally complex class of glycosaminoglycans (GAGs) that have been implicated in a wide range of biological activities. [PMID:31016560]

publication : 23313092|31016560|23152789

definition : 

term_xref :  

synonyms :  HS/heparin|heparan sufate (HS)/heparin|H/HS

function : 

disease_associations : 

wikipedia :  

essentials_of_glycobiology :


GSD000186

G00031MO
term (main_entry) : Core 1

glycan_dictionary_accession : GSD000186

glytoucan_accession  : G00031MO

term_in_sentence : O-glycans are initiated by the addition of GalNAc to serine or threonine (via the ppGalNAcT family of glycosyltransferases), forming the Tn antigen (GalNAcα-O-Ser/Thr), which is used to generate the core 1 structure (Galβ1,3GalNAcα-O-Ser/Thr) on which most complex and branched O-glycans are derived. [PMID:31645367]

publication : 31645367|32297877

definition : 

term_xref : GTC:G00031MO|GlycoMotif:GGM.001005 

synonyms :  C1G

function : 

disease_associations : 

wikipedia :  

essentials_of_glycobiology :


GSD000187

G99315PE
term (main_entry) : Blood group A (Type 3)

glycan_dictionary_accession : GSD000187

glytoucan_accession  : G99315PE

term_in_sentence : 

publication : 7800218|17998569|19756298|3191504

definition : 

term_xref : GlycoMotif:GGM.000011|GTC:G99315PE

synonyms :  A type 3 antigen|blood group A type 3|A antigen (type 3)

function : 

disease_associations : 

wikipedia :  

essentials_of_glycobiology :  Chapter 14


GSD000188

G80722US
term (main_entry) : 6-Sulfo Sialyl Lewis x 

glycan_dictionary_accession : GSD000188

glytoucan_accession  : G80722US 

term_in_sentence : The cognate ligands for L-selectin possess the unusual sulfated tetrasaccharide epitope 6-sulfo sialyl Lewis x (Siaalpha2-->3Galbeta1-->4[Fucalpha1-->3][SO(3)-->6]GlcNAc).[PMID:11331001] 

publication : 11331001|2288521|26137907|9400621|[https://pubmed.ncbi.nlm.nih.gov/9556613 9556613 9556613]|15972893|9015359|22691873|18652681|9722682|10435581|19359410|15228275|18250165|10536036|17944600|10460836|27993973|19149511|19150806|17172261|17142960|27956273|7578028|22260995|24519996|21596021|21982762|21775439|17334369|9710564|14593101|16227985|11895802|22750968|15157883|19067429 

definition : 

term_xref : GlycoMotif:GGM.000027|GlycoEpitope:EP0015|CID:70698321|CHEBI:71628

synonyms : 6-sulfo SLex|6-Sulfo-sialyl Lewis x|6-sulfo SLe^x 

function : lymphocyte homing[GlycoEpitope:EP0015]

disease_associations : 

wikipedia :  

essentials_of_glycobiology : Chapter 34|Chapter 35


GSD000189

G89208KM
term (main_entry) : Blood group B (Type 1) - Lewis b

glycan_dictionary_accession : GSD000189

glytoucan_accession  : G89208KM 

term_in_sentence :  Ten monoclonal antibodies and one lectin were used to study the localization and distribution of Blood Group ABH, type 1 chain (Lewis a, Lewis b) and type 2 chain (H-2, Y) antigens in 22 cases of normal uterine cervix, with known ABO and Lewis phenotype and secretor status. [PMID:2247887]

publication :  2247887|19756298|30831115

definition :  

term_xref : GlycoMotif:GGM.000046

synonyms :  Blood Group B, type 1 chain (Lewis b)|B-Leb|B-Le^b

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000190

G97501MA
term (main_entry) : Blood group A (Type 1) - Lewis b

glycan_dictionary_accession : GSD000190

glytoucan_accession  : G97501MA 

term_in_sentence :  Ten monoclonal antibodies and one lectin were used to study the localization and distribution of Blood Group ABH, type 1 chain (Lewis a, Lewis b) and type 2 chain (H-2, Y) antigens in 22 cases of normal uterine cervix, with known ABO and Lewis phenotype and secretor status.[PMID:2247887]

publication :  2247887|19756298|4041428|5686860

definition :  A branched amino pentasaccharide consisting of the linear trisaccharide N-acetyl-α-D-galactosaminyl-(1→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosamine having α-L-fucosyl residues attached at position 2 of the galactose and position 4 of the glucosamine. Corresponds to a partial structure of blood group A type 1 oligosaccharide.[CHEBI:62988]

term_xref : GlycoMotif:GGM.000047|CID:53477630|CHEBI:62988|GlycoEpitope:EP0260

synonyms :  Blood Group A Type 1 (difucosyl)|ALe^b|A-Leb|A-Le^b|A Lewis b

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000191

G18464VS
term (main_entry) : Sulfated LacdiNAc

glycan_dictionary_accession : GSD000191

glytoucan_accession  : G18464VS 

term_in_sentence :  The mRNA expression of the enzymes related to the formation of sulfated LacdiNAc:β(1,4)-N-acetylgalactosaminyltransferases 3 (B4GALNT3) and 4 (B4GALNT4), carbohydrate sulfotransferases 8 (CHST8) and 9 (CHST9); and β(1,4)-galactosyltransferase 1 (B4GALT1) in these cells was confirmed by RT-PCR (Fig. S4).[PMID:31558607]

publication :  31558607|27318476|19756298|11279168|26688390

definition :  

term_xref : GlycoMotif:GGM.000049

synonyms :  4'-O-sulfated LacdiNAc|4'-sulfated LDN|sulfated LDN

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


GSD000192

G55583HW
term (main_entry) : Sialylated LacdiNAc

glycan_dictionary_accession : GSD000192

glytoucan_accession  : G55583HW 

term_in_sentence :  The major non-reducing epitopes in the complex-type glycans are: Gal beta 1-4GlcNAc (lacNAc), GalNAc beta 1-4GlcNAc (lacdiNAc), NeuAc alpha 2-6Gal beta 1-4GlcNAc (sialylated lacNAc), NeuAc alpha 2-6Gal beta 1-4GlcNAc (sialylated lacdiNAc), Gal beta 1-4(Fuc alpha 1-3)GlcNAc (Lewisx), and GalNAc beta 1-4(Fuc alpha 1-3)GlcNAc (lacdiNAc analogue of Lewisx).[PMID:7592613]

publication :  7592613|34192302|19756298|16286643

definition :  

term_xref : GlycoMotif:GGM.000050

synonyms :  sialylated-LacdiNAc|Sialylated LDN

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :


Retired Terms (by Term Name)

A2

G62735WZ
term (main_entry) : A2 

glycan_dictionary_accession : GSD000015 

glytoucan_accession  : G62735WZ 

term_in_sentence : Landsteiner ABO system of blood groups is most important for transfusion medicine and has subtypes of A Antigen, A1 and A2, upon which further groups of A and AB have been classified.[PMID:28658771] 

publication : 29000000|28658771 

definition :  

term_xref : GlycoMotif:GGM.000041|GTC:G62735WZ|CID:[https://pubmed.ncbi.nlm.nih.gov/91852328 91852328 91852328] 

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

date retired : 01/27/2023 

reason for retirement : Duplicated entry. See GSD000032.


Chitin

term (main_entry) : Chitin (This term has been retired.)

glycan_dictionary_accession : GSD000042 

glytoucan_accession  :  

term_in_sentence : In this review, we will focus on the prevalence and structural function of chitin in bacteria, fungi, and protists, with a particular focus on the evolution of chitin synthases and the function of chitin oligosaccharides as a signaling molecule in symbiosis and immunity[PMID: 31102241] 

publication : [https://pubmed.ncbi.nlm.nih.gov/25738328 25738328 25738328]|[https://pubmed.ncbi.nlm.nih.gov/31102247 31102247 31102247]|[https://pubmed.ncbi.nlm.nih.gov/26982439 26982439 26982439]|[https://pubmed.ncbi.nlm.nih.gov/31685194 31685194 31685194]|[https://pubmed.ncbi.nlm.nih.gov/29197571 29197571 29197571]|[https://pubmed.ncbi.nlm.nih.gov/29182521 29182521 29182521]|[https://pubmed.ncbi.nlm.nih.gov/25725011 25725011 25725011]|[https://pubmed.ncbi.nlm.nih.gov/27787767 27787767 27787767]|[https://pubmed.ncbi.nlm.nih.gov/21736263 21736263 21736263]|[https://pubmed.ncbi.nlm.nih.gov/25300540 25300540 25300540]|[https://pubmed.ncbi.nlm.nih.gov/30840869 30840869 30840869]|[https://pubmed.ncbi.nlm.nih.gov/25081074 25081074 25081074]|[https://pubmed.ncbi.nlm.nih.gov/28250359 28250359 28250359]|[https://pubmed.ncbi.nlm.nih.gov/29763421 29763421 29763421]|[https://pubmed.ncbi.nlm.nih.gov/29910219 29910219 29910219]|[https://pubmed.ncbi.nlm.nih.gov/20161969 20161969 20161969]|[https://pubmed.ncbi.nlm.nih.gov/32019265 32019265 32019265]|[https://pubmed.ncbi.nlm.nih.gov/30879650 30879650 30879650]|[https://pubmed.ncbi.nlm.nih.gov/12587986 12587986 12587986]|[https://pubmed.ncbi.nlm.nih.gov/29773374 29773374 29773374]|[https://pubmed.ncbi.nlm.nih.gov/31376451 31376451 31376451]|[https://pubmed.ncbi.nlm.nih.gov/10906950 10906950 10906950]|[https://pubmed.ncbi.nlm.nih.gov/26096004 26096004 26096004]|[https://pubmed.ncbi.nlm.nih.gov/25595947 25595947 25595947]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932]]]|[https://pubmed.ncbi.nlm.nih.gov/29452181 29452181 29452181]|[https://pubmed.ncbi.nlm.nih.gov/24083454 24083454 24083454]|[https://pubmed.ncbi.nlm.nih.gov/10856926 10856926 10856926]|[https://pubmed.ncbi.nlm.nih.gov/22732132 22732132 22732132]|[https://pubmed.ncbi.nlm.nih.gov/18657571 18657571 18657571]|[https://pubmed.ncbi.nlm.nih.gov/29175166 29175166 29175166]|[https://pubmed.ncbi.nlm.nih.gov/28842199 28842199 28842199]|[https://pubmed.ncbi.nlm.nih.gov/27592817 27592817 27592817]|[https://pubmed.ncbi.nlm.nih.gov/27302593 27302593 27302593]|[https://pubmed.ncbi.nlm.nih.gov/27339323 27339323 27339323]|[https://pubmed.ncbi.nlm.nih.gov/12705640 12705640 12705640]|[https://pubmed.ncbi.nlm.nih.gov/31635752 31635752 31635752]|[https://pubmed.ncbi.nlm.nih.gov/31063786 31063786 31063786]|[https://pubmed.ncbi.nlm.nih.gov/31151236 31151236 31151236]|[https://pubmed.ncbi.nlm.nih.gov/25940531 25940531 25940531]|[https://pubmed.ncbi.nlm.nih.gov/26093316 26093316 26093316]|[https://pubmed.ncbi.nlm.nih.gov/28962761 28962761 28962761]|[https://pubmed.ncbi.nlm.nih.gov/28093332 28093332 28093332]|[https://pubmed.ncbi.nlm.nih.gov/30875044 30875044 30875044]|[https://pubmed.ncbi.nlm.nih.gov/27723949 27723949 27723949]|[https://pubmed.ncbi.nlm.nih.gov/28119189 28119189 28119189]|[https://pubmed.ncbi.nlm.nih.gov/30600008 30600008 30600008]|[https://pubmed.ncbi.nlm.nih.gov/25081085 25081085 25081085]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932]]] 

definition : An aminoglycan consisting of β-(1→4)-linked N-acetyl-D-glucosamine residues.[CHEBI:17029] 

term_xref : CHEBI:17029

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  Chapter 26

date retired : 01/27/2023 

reason for retirement : Not including linear polysaccharides to glycan structure dictionary.


Retired Terms (by Glycan Dictionary Accessions)

GSD000015

G62735WZ
term (main_entry) : A2 

glycan_dictionary_accession : GSD000015 

glytoucan_accession  : G62735WZ 

term_in_sentence : Landsteiner ABO system of blood groups is most important for transfusion medicine and has subtypes of A Antigen, A1 and A2, upon which further groups of A and AB have been classified.[PMID:28658771] 

publication : 29000000|28658771 

definition :  

term_xref : GlycoMotif:GGM.000041|GTC:G62735WZ|CID:[https://pubmed.ncbi.nlm.nih.gov/91852328 91852328 91852328] 

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

date retired : 01/27/2023 

reason for retirement : Duplicated entry. See GSD000032.


GSD000042

term (main_entry) : Chitin 

glycan_dictionary_accession : GSD000042 

glytoucan_accession  :  

term_in_sentence : In this review, we will focus on the prevalence and structural function of chitin in bacteria, fungi, and protists, with a particular focus on the evolution of chitin synthases and the function of chitin oligosaccharides as a signaling molecule in symbiosis and immunity[PMID: 31102241] 

publication : [https://pubmed.ncbi.nlm.nih.gov/25738328 25738328 25738328]|[https://pubmed.ncbi.nlm.nih.gov/31102247 31102247 31102247]|[https://pubmed.ncbi.nlm.nih.gov/26982439 26982439 26982439]|[https://pubmed.ncbi.nlm.nih.gov/31685194 31685194 31685194]|[https://pubmed.ncbi.nlm.nih.gov/29197571 29197571 29197571]|[https://pubmed.ncbi.nlm.nih.gov/29182521 29182521 29182521]|[https://pubmed.ncbi.nlm.nih.gov/25725011 25725011 25725011]|[https://pubmed.ncbi.nlm.nih.gov/27787767 27787767 27787767]|[https://pubmed.ncbi.nlm.nih.gov/21736263 21736263 21736263]|[https://pubmed.ncbi.nlm.nih.gov/25300540 25300540 25300540]|[https://pubmed.ncbi.nlm.nih.gov/30840869 30840869 30840869]|[https://pubmed.ncbi.nlm.nih.gov/25081074 25081074 25081074]|[https://pubmed.ncbi.nlm.nih.gov/28250359 28250359 28250359]|[https://pubmed.ncbi.nlm.nih.gov/29763421 29763421 29763421]|[https://pubmed.ncbi.nlm.nih.gov/29910219 29910219 29910219]|[https://pubmed.ncbi.nlm.nih.gov/20161969 20161969 20161969]|[https://pubmed.ncbi.nlm.nih.gov/32019265 32019265 32019265]|[https://pubmed.ncbi.nlm.nih.gov/30879650 30879650 30879650]|[https://pubmed.ncbi.nlm.nih.gov/12587986 12587986 12587986]|[https://pubmed.ncbi.nlm.nih.gov/29773374 29773374 29773374]|[https://pubmed.ncbi.nlm.nih.gov/31376451 31376451 31376451]|[https://pubmed.ncbi.nlm.nih.gov/10906950 10906950 10906950]|[https://pubmed.ncbi.nlm.nih.gov/26096004 26096004 26096004]|[https://pubmed.ncbi.nlm.nih.gov/25595947 25595947 25595947]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932]]]|[https://pubmed.ncbi.nlm.nih.gov/29452181 29452181 29452181]|[https://pubmed.ncbi.nlm.nih.gov/24083454 24083454 24083454]|[https://pubmed.ncbi.nlm.nih.gov/10856926 10856926 10856926]|[https://pubmed.ncbi.nlm.nih.gov/22732132 22732132 22732132]|[https://pubmed.ncbi.nlm.nih.gov/18657571 18657571 18657571]|[https://pubmed.ncbi.nlm.nih.gov/29175166 29175166 29175166]|[https://pubmed.ncbi.nlm.nih.gov/28842199 28842199 28842199]|[https://pubmed.ncbi.nlm.nih.gov/27592817 27592817 27592817]|[https://pubmed.ncbi.nlm.nih.gov/27302593 27302593 27302593]|[https://pubmed.ncbi.nlm.nih.gov/27339323 27339323 27339323]|[https://pubmed.ncbi.nlm.nih.gov/12705640 12705640 12705640]|[https://pubmed.ncbi.nlm.nih.gov/31635752 31635752 31635752]|[https://pubmed.ncbi.nlm.nih.gov/31063786 31063786 31063786]|[https://pubmed.ncbi.nlm.nih.gov/31151236 31151236 31151236]|[https://pubmed.ncbi.nlm.nih.gov/25940531 25940531 25940531]|[https://pubmed.ncbi.nlm.nih.gov/26093316 26093316 26093316]|[https://pubmed.ncbi.nlm.nih.gov/28962761 28962761 28962761]|[https://pubmed.ncbi.nlm.nih.gov/28093332 28093332 28093332]|[https://pubmed.ncbi.nlm.nih.gov/30875044 30875044 30875044]|[https://pubmed.ncbi.nlm.nih.gov/27723949 27723949 27723949]|[https://pubmed.ncbi.nlm.nih.gov/28119189 28119189 28119189]|[https://pubmed.ncbi.nlm.nih.gov/30600008 30600008 30600008]|[https://pubmed.ncbi.nlm.nih.gov/25081085 25081085 25081085]|[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932]] [https://pubmed.ncbi.nlm.nih.gov/[https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932] [https://pubmed.ncbi.nlm.nih.gov/21673932 21673932 21673932]]] 

definition : An aminoglycan consisting of β-(1→4)-linked N-acetyl-D-glucosamine residues.[CHEBI:17029] 

term_xref : CHEBI:17029 

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  Chapter 26

date retired : 01/27/2023 

reason for retirement : Not including linear polysaccharides to glycan structure dictionary.


Submit new terms

If you feel that a term is missing, you can submit a single term using the online form found at https://data.glygen.org/gsd/ . To submit multiple terms you can use GlyGen file upload https://data.glygen.org/uploads. Template for submitting terms can be found here. Contact https://www.glygen.org/contact-us/ for any questions.

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