Testhyperlink123

GSD000031

term (main_entry) : Blood group A1 (Type 3) 

glycan_dictionary_accession : GSD000031 

glytoucan_accession  : G44060QH 

term_in_sentence : The structure is essentially a repetitive A epitope attached to type 2 chain and is hereby called type 3 chain A. [PMID:2579390] 

publication : 2579390|19756298 

definition : A branched amino heptasaccharide made up from two repeating (1→3)-linked N-acetyl-α-D-galactosaminyl-(1→3)-[α-L-fucosyl-(1→2)]-β-D-galactosyl units that are in turn joined to an N-acetyl-β-D-glucosamine residue via a (1→4)-linkage.[CHEBI:85665] 

term_xref : GTC:G44060QH|CHEBI:85665|CID:91825676|GlycoMotif:GGM.000040  

synonyms : Blood group A1 (type 3)|Blood Group A1 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000032

G62735WZ

term (main_entry) : Blood group A2 (A-associated H type 3) 

glycan_dictionary_accession : GSD000032 

glytoucan_accession  : G62735WZ 

term_in_sentence : The H NMR spectrum of the associated H antigen (type 3 chain H) was characterized by the unusual presence of three n-anomeric resonances ('CJ'.~ = 3-4 Hz) in addition to five resonances from @-anomeric protons ("J1:2 = 7-9 Hz).[PMID: 3944091]
publication : 3944091|29000000|28658771 

definition : A branched amino hexasaccharide in which an α-L-fucosyl-(1→2)-β-D-galactosyl-(1→3)-N-acetyl-α-D-galactosaminyl-(1→3)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine linear pentasaccharide carries at the galactose residue proximal to the reducing end a second α-L-fucosyl residue via a (1→2) linkage.[CHEBI:152543] 

term_xref : CHEBI:152543|CID: 91852328|GlycoMotif:GGM.000041|GTC:G62735WZ 

synonyms : Blood Group A2|Fuca1-2Galb1-3GalNAca1-3(Fuca1-2)Galb1-4GlcNAcb|Fuc(a1-2)Gal(b1-3)GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)b-GlcNAc|Fucalpha1-2Galbeta1-3GalNAcalpha1-3(Fucalpha1-2)Galbeta1-4GlcNAcbeta|6-deoxy-alpha-L-galacto-hexopyranosyl-(1→2)-beta-D-galacto-hexopyranosyl-(1→3)-2-acetamido-2-deoxy-alpha-D-galacto-hexopyranosyl-(1→3)-[6-deoxy-alpha-L-galacto-hexopyranosyl-(1→2)]-beta-D-galacto-hexopyranosyl-(1→4)-2-acetamido-2-deoxy-beta-D-gluco-hexopyranose|6-deoxy-alpha-L-galactopyranosyl-(1→2)-[6-deoxy-alpha-L-galactopyranosyl-(1→2)-beta-D-galactopyranosyl-(1→3)-2-acetamido-2-deoxy-alpha-D-galactopyranosyl-(1→3)]-beta-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-beta-D-glucopyranose 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000033

G31734OS

term (main_entry) : Blood group B (Type 1) 

glycan_dictionary_accession : GSD000033 

glytoucan_accession  : G31734OS 

term_in_sentence : The minimal binding epitope was identified as the blood group H type 1 determinant (Fucα2Galβ3GlcNAc), while an optimal binding epitope was created by addition of the terminal α3-linked galactose or N-acetylgalactosamine of the blood group B type 1 determinant (Galα3(Fucα2)Galβ3GlcNAc) and the blood group A type 1 determinant (GalNAcα3(Fucα2)-Galβ3GlcNAc). [PMID: 19208633] 

publication : 18701592|24749871|19387828|19208633|29562255 

definition : α-D-Galp-(1→3)-[α-L-Fucp-(1→2)]-β-D-Galp-(1→3)-β-D-GlcpNAc with β configuration at the anomeric carbon of the GlcNAc residue at the reducing end.[CHEBI:63242] 

term_xref : GlycoMotif:GGM.000043|GTC:G31734OS|CID:56927779|CHEBI:63242 

synonyms : blood group B type 1 tetrasaccharide 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000034

term (main_entry) : Blood group B (Type 2) 

glycan_dictionary_accession : GSD000034 

glytoucan_accession  : G34881WK 

term_in_sentence : The detection of a B type 2 determinant is the first chemical evidence for the presence of an autologous difucosyl blood group B type 2 antigen in human adenocarcinoma cells.[PMID: 2432062] 

publication : 2432062|27196314|18701592 

definition :  

term_xref : GlycoMotif:GGM.000037|GTC:G34881WK|GlycoEpitope:EP0262  

synonyms : blood group B type 2 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000035

term (main_entry) : Blood group B (Type 4) 

glycan_dictionary_accession : GSD000035 

glytoucan_accession  : G25216QA 

term_in_sentence : The blood group B type-4 heptaglycosylceramide is a minor blood group B structure in human B kidneys in contrast to the corresponding A type-4 compound in A kidneys.[PMID:1390942] 

publication : 1390942|1841684 

definition :  

term_xref : GlycoMotif:GGM.000087|GTC:G25216QA  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000036

term (main_entry) : Blood group H (Type 1) 

glycan_dictionary_accession : GSD000036 

glytoucan_accession  : G00294TN 

term_in_sentence : Blood group H type 1 [Fuc alpha (1,2)Gal beta (1,3)GlcNAc beta-->] is known as the precursor structure of the blood group determinant, Lewis b [Fuc alpha (1,2)Gal beta (1,3)(Fuc alpha (1,4))GlcNAc beta-->].[PMID:7718581] 

publication : 7718581|6309836|19208633|27431816| 2432062|24219248|6352465|8499478|3348768|3718924 

definition :  

term_xref : GTC:G00294TN|GlycoMotif:GGM.000042|SugarBind_Ligand:153  

synonyms : H type 1 

function :  

disease_associations : Gastroenteritis[SugarBind_Ligand:153] 

wikipedia :  

essentials_of_glycobiology :  

GSD000037

G70519XK

term (main_entry) : Blood group H (Type 2) 

glycan_dictionary_accession : GSD000037 

glytoucan_accession  : G70519XK 

term_in_sentence : We have examined the immunohistochemical distribution of H Type 1 and of H Type 2 substances of the ABO blood group system in human submandibular gland using either of the two anti-H monoclonal antibodies MAb 1E3 and MAb 3A5. MAb 3A5 was specific for H Type 2, and MAb 1E3 reacted with each of H Type 1-H Type 4 artificial antigens.[PMID: 9405495] 

publication : 9405495|8082855|6177241|3944092|21406562|2410664|8731502|6203846|2238560| 

definition :  

term_xref : GTC:G70519XK|GlycoMotif:GGM.000036  

synonyms : Blood group H (type 2)|H type 2|H type 2 chain|H type 2 antigen|type 2 chain H|blood group H type II 

function : 

disease_associations : 

wikipedia :  

essentials_of_glycobiology :  

GSD000038

G00052MO

term (main_entry) : Blood group H (Type 2) - Lewis y 

glycan_dictionary_accession : GSD000038 

glytoucan_accession  : G00052MO 

term_in_sentence : The fucosylated histo-blood group antigens H type 2 (blood group O, CD173) and Lewis Y (CD174) are expressed on CD34+ hematopoietic progenitors but absent on mature lymphocytes.[PMID: 11479278] 

publication : 11479278 

definition : A branched amino tetrasaccharide consisting of N-acetyl-β-D-glucosamine at the reducing end having an α-L-fucosyl residue attached at the 3-position and an α-L-fucosyl-(1→2)-β-D-galactosyl moiety attached at the 4-position. A cancer-associated tetrasaccharide antigen which constitutes the core structure recognised by therapeutic antibody BR96. Conformational restriction around the GlcNAc residue is a key feature of its structure.[CHEBI:59045] 

term_xref : GTC:G00052MO|GlycoEpitope:EP0018|CID:45266908|CHEBI:59045|GlycoMotif:GGM.000045  

synonyms : Lewis y|Blood group H (type 2) (Ley)|Lewis b (Leb)|Lewis a|Lewis b (Lewis b)|Blood group H (type 2) - Lewis y|H-Ley|H-Le^y|Lewis Y|H-Ley|H-Le^y|Lewis Y 

function : The expression of the fucosylated histo-blood group antigen CD174 in CD34+ hematopoietic progenitor cells and down-regulation of FUT1 in mature lymphocytes may be important factors influencing the homing process of hematopoietic stem cells to the bone marrow.[GlycoEpitope:EP0018] 

disease_associations : AIDS/acquired immune deficiency syndrome[GlycoEpitope:EP0018]|cholangiocarcinoma[GlycoEpitope:EP0018]|hepatocellular carcinoma[GlycoEpitope:EP0018]|Inappropriate tissue distribution of Ley blood-group antigens was observed in CCs(cholangiocarcinomas) and, much less frequently, in HCCs(hepatocellular carcinomas).[GlycoEpitope:EP0018]|Ley determinant is highly expressed in human immunodeficiency virus (HIV)-infected T cell lines and in CD3+ peripheral mature T cells of patients with acquired immune deficiency syndrome (AIDS) or with AIDS-related complex (ARC).[GlycoEpitope:EP0018] 

wikipedia :  

essentials_of_glycobiology : Chapter 14

GSD000039

term (main_entry) : Blood group H (Type 4) 

glycan_dictionary_accession : GSD000039 

glytoucan_accession  : G98465JN 

term_in_sentence : In addition, the blood group H type 4 chain structure was present together with Le(a) and Le(b) compounds.[PMID:1841684] 

publication : 11261842| 1841684|11101633|9405495 

definition : An amino hexasaccharide consisting of α-L-fucose, β-D-galactose, N-acetyl-α-D-galactosamine, α-D-galactose, β-D-galactose and β-D-glucose residues joined in sequence with (1→2)-, (1→3)-, (1→3)-, (1→4)- and (1→4)-linkages, respectively.[CHEBI:65245] 

term_xref : GlycoMotif:GGM.000086|GTC:G98465JN|CID:10260428|SugarBind_Ligand:61|CHEBI:65245

synonyms :  

function :  

disease_associations : Pyelonephritis[SugarBind_Ligand:61] 

wikipedia :  

essentials_of_glycobiology :  

GSD000040

term (main_entry) : C2-O-sLex 

glycan_dictionary_accession : GSD000040 

glytoucan_accession  : G97345NY 

term_in_sentence : PSGL-1 lacks 6-sulfo-sLex but contains sulfated tyrosine residues (Tyr-SO3)at positions 46, 48, and 51 and sLex in a core 2-based O-glycan (C2-O-sLex) on Thr at position 57.[PMID:12736247] 

publication : 12736247|19267921|21283832|15596301|17072011 

definition : A seven-membered branched galactosamine oligosaccharide that consists of a branched tetrasaccharide unit α-Neu5Ac-(2→3)-β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc, attached by a glycosidic linkage to position 6 of the GalNAc residue of the trisaccharide α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-D-GalNAc.[CHEBI:65192] 

term_xref : GlycoMotif:GGM.000053|GTC:G97345NY|CID:91860725|KEGG:G10899|CHEBI:155160  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000041

G04416BG

term (main_entry) : Ceramide dihexosyl sulfate 

glycan_dictionary_accession : GSD000041 

glytoucan_accession  : G04416BG 

term_in_sentence : Although it has been reported that ceramide dihexosyl sulfate is present in human kidney, it is unlikely that it is present in equine kidney.[PMID:818074] 

publication : 818074 

definition : A sulfatide with two hexose moieties (glucose and galactose) has been isolated from human kidney (Martensson E, Acta Chem Scand 1963, 17, 1174). Equimolar amounts of ceramide, glucose, galactose, and sulfate are found in the molecule. The sulfate group is esterified, as in sulfatides, with carbon 3 of the galactose moiety. The linkage between galactose and glucose is identical to lactose (b-1-4). Its fatty acid composition is similar to that of sulfatides. [http://cyberlipid.gerli.com/description/complex-lipids/glycolipids/glycosphingolipids/sulfosphingolipids/] 

term_xref : GTC:G04416BG|GlycoMotif:GGM.000065 

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000043

term (main_entry) : Chondroitin sulfate 

glycan_dictionary_accession : GSD000043 

glytoucan_accession  :  

term_in_sentence : The industrial production of chondroitin sulfate (CS) uses animal tissue sources as raw material derived from different terrestrial or marine species of animals.[PMID: 31013685] 

publication : 31013685|27526113|27194526|26980567|28847361|24413804|29891297|29600622|25129732|31317901|29181550|31250530|22265655|25756648|29402610|17928217|20236040|28091940|30824935|26572336|31207331|21110089|30599999|20399897|27226567|19388612|23186102|31494830|28982096|30241863|30295666|25366475|20521042|29456007|31304829|18661362|28576008|29494632|30016441|26906924|24861964|23774590|31887904|31339761| 12512856|26957048|29625000 

definition : Any of a class of 10‚Äî60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues.[CHEBI:37397] 

term_xref : CHEBI:37397|CID:24766 

synonyms : chondroitin polysulfate|chondroitin sulfate|chondroitin sulfates|chondroitin sulfuric acid|chondroitin sulphate|Chondroitinsulfate 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000044

term (main_entry) : cisGM1 

glycan_dictionary_accession : GSD000044 

glytoucan_accession  : G03277YI 

term_in_sentence : Macrophage ganglioside patterns dramatically increase in complexity when murine peritoneal macrophages are stimulated in vivo with the appearance of the sialidase-sensitive monosialoganglioside GM1b (cisGM1) as a major component.[PMID: 9455923] 

publication : 9455923 

definition : A member of the class of neuraminic acids that is neuraminic acid attached in sequence to β-D-galactopyranosyl, 2-acetamido-2-deoxy-β-D-galactopyranosyl, β-D-galactopyranosyl, and β-D-gucoopyranose units by (2→3), (1→3), (1→4), and (1→4) glycosidic linkages, respectively. It corresponds to the carbohydrate portion of ganglioside GM1b.[CHEBI:145580] 

term_xref : GlycoMotif:GGM.000100|GTC:G03277YI|CID:91850212|CHEBI:145580|GlycoEpitope:EP0048|SugarBind_Ligand:92|KEGG:G00125 

synonyms : GM1b 

function :  

disease_associations : Influenza[SugarBind_Ligand:92] 

wikipedia :  

essentials_of_glycobiology : Chapter 23

GSD000045

term (main_entry) : Complex-type N-glycans 

glycan_dictionary_accession : GSD000045 

glytoucan_accession  :  

term_in_sentence : In this study, 32 new complex-type glycans are characterized containing the Le(x), Le(Y), and sialyl-Le(x) determinants, the bloodgroup A and H antigens, as well as the ALe(Y) determinant.[PMID:10988252 

publication : 29902282|29212795|29343819|27705835|26745022|18399796|16825488|21964725|15864431|22890903|12417032|28039392|19426135|30253927|16794314|19806620|22975979|25931033|15201278|19129634|19129628|24032650|22530754|31021709|30973186|28091941|23115339|20829342|27304954|29090617|21802690|29725121|30471292|16581187|26098720|31080188|1930135|31888963|30844485|24014058|11129583 

definition : Type of N-linked glycan in which at least two antenna are present on the trimannosyl core, each initiated by GlcNAc additions catalyzed by position-specific N-acetylglucosaminyltransferases (GlcNAcTs). Each antenna can be exteneded or capped with HexNAc, deoxyHex, Hex, or sialic acid residues.  

term_xref :  

synonyms :  

function : Involved in protein stability.[PMID:12417032] 

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 17

GSD000046

term (main_entry) : Core 2 

glycan_dictionary_accession : GSD000046 

glytoucan_accession  : G00033MO 

term_in_sentence : To investigate the biological roles of core 2 O-glycans, we produced and characterized mice deficient in one or more of the three known glycosyltransferases that generate core 2 O-glycans (C2GnT1, C2GnT2, and C2GnT3).[PMID: 19349303] 

publication : 19349303|30315106|23640779|26677400 

definition : The trisaccharide β-D-Gal-(1→3)-[β-D-GlcNAc-(1→6)]-D-GalNAc with α configuration at the anomeric centre of the N-acetylglucosamine residue at the reducing end.[CHEBI:62158] 

term_xref : GTC:G00033MO|CID: 52921656|CHEBI:62158  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000047

term (main_entry) : Core 3 

glycan_dictionary_accession : GSD000047 

glytoucan_accession  : G00035MO 

term_in_sentence : Mechanically, we revealed that mucin-type core 3 O-glycan was synthesized at the membrane-tethered MUC1 N terminus because of core 3 synthase expression in colon cancer cells.[PMID: 28745318] 

publication : 28745318|27259834|27143302| 

definition : An amino disaccharide comprising an N-acetyl-β-D-glucosamine residue linked (1→3) to an N-acetyl-β-D-galactosamine residue at the reducing end.[CHEBI:71344] 

term_xref : GTC:G00035MO|CID:25061208|CHEBI:71344  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 9 

GSD000048

term (main_entry) : Core 4 

glycan_dictionary_accession : GSD000048 

glytoucan_accession  : G00037MO 

term_in_sentence : The results confirm the predicted existence of a beta1,6GlcNAc-transferase that functions in both core 2 and core 4 O-glycan branch formation.[PMID: 9988682] 

publication : 9988682|10747980| 

definition : A branched amino trisaccharide comprising an N -acetyl-α-D-galactosamine residue at the reducing end, to which are (1→3)- and (1→6)-linked two N -acetyl-α-D-glucosamine residues.[CHEBI:71341] 

term_xref : GTC:G00037MO| CID:25229562|CHEBI:71341 

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 8

GSD000049

G78059CC

term (main_entry) : Core-fucosylated 

glycan_dictionary_accession : GSD000049 

glytoucan_accession  : G78059CC 

term_in_sentence : The approach was validated for selective capture and analysis of core fucosylated N-glycans present in complex glycan mixtures derived from mammalian serum IgG.[PMID:27678371] 

publication : 27678371|26514868|15538974|24914453| 17049014|32078267|31268672|28674882|29956878|27798819|32044029|30962950|31548313|30907281|29090617|29571940|28800497|27629418|29733746|31623829|28768188|26897254|31451706|26514868]|29427759|28982386|26587313|30940702| 15538974|31249452|27282921|31229844|30445455|31325506|24732908|29209018|26965517|28609658| 24914453|25573275|17049014|19218400|27012207|27139574| 32078267|25861849|32561391|21374780|31669139|25732060|29408166|31268672|30472795|30614075|19003000|25664929 

definition : Modification of the N-glycan core structure with fucose moiety attached at the innermost GlcNAc by FUT8 enzyme. Core Fuc is found on paucimannose, hybrid and complex type N-glycans. [https://doi.org/10.1016/bs.acr.2014.11.006]. 

term_xref : GTC:G78059CC|CID: 70679232|CHEBI:70967|CHEBI:156499 

synonyms : Core Fuc|6-linked Fuc|Fuca6 to chitobiose core|a6-linked Fuc|a1-6 Fuc|Fuca6 to chitobiose core|Fuc a1-6 to chitobiose core|Fuca6 to internal GlcNAc|Fuc a1-6 to internal GlcNAc 

function : Required for signaling through TCR [PMID: 29434598]|VGF, PDGFr, and EGFr and TGFbeta receptor dysregulation in Fut8 KO mice [PMID:17132494]|IgG-Fcg receptor interactions destabilized by core Fuc [PMID:29062024] 

disease_associations : Emphysema|systemic lupus erythematosuslung cancer|autoimmunity|tumor metastasis 

wikipedia :  

essentials_of_glycobiology : Chapter 8 

GSD000050

term (main_entry) : Core-fucosylated biantennary 

glycan_dictionary_accession : GSD000050 

glytoucan_accession  : G78059CC 

term_in_sentence : The IFN-alpha14c N-glycans were shown to exhibit core-fucosylated biantennary glycans , with about 10% carrying an additional alpha1,3-linked fucose unit at the antennae.[PMID:9654101] 

publication : 9654101|15819890|28263871|26763099|22256781|23681398|25855029|10529240|26544759|8206921|33149259|8547276 

definition : A biantennary glycan with two GlcNAc branches linked to the core and fucosylation on the core GlcNAc. 

term_xref : GTC:G78059CC|CID:70679232|CHEBI:70967|CHEBI:156499 

synonyms : core-fucosylated diantennary 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 8 

GSD000051

term (main_entry) : Core-fucosylated biantennary complex-type 

glycan_dictionary_accession : GSD000051 

glytoucan_accession  : G78059CC 

term_in_sentence : The oligosaccharide structure at Asn(32 ) is a mixture of the monosialo and asialo forms of a core fucosylated biantennary complex-type oligosaccharide.[PMID:10731668] 

publication : 10731668 

definition : A biantennary complex glycan with two GlcNAc branches linked to the core and fucosylation on the core GlcNAc. 

term_xref : GTC:G78059CC|CID:70679232|CHEBI:70967|CHEBI:156499  

synonyms : core fucosylated diantennary complex-type 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000052

G11148DZ

term (main_entry) : Cyclic sialyl 6-sulfo Lewis x 

glycan_dictionary_accession : GSD000052 

glytoucan_accession  :  G11148DZ

term_in_sentence : Stimulation of the sialyl 6-sulfo Lewis X-positive colon cancer cell line with a calcium ionophore ionomycin markedly reduced sialyl 6-sulfo Lewis X and induced cyclic sialyl 6-sulfo Lewis X expression.[PMID:10728707] 

publication : 10728707|31222115|9990070|23088960 

definition :  

term_xref :  GlycoEpitope:EP0017|CID: 91858084|CHEBI:147484

synonyms :  

function : The accumulated intracellular cyclic sialyl 6-sulfo Lex determinant may function as a dormant pool of selectin ligands.[GlycoEpitope:EP0017] 

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000053

term (main_entry) : Cytolipin R 

glycan_dictionary_accession : GSD000053 

glytoucan_accession  : G57710SU 

term_in_sentence : The reaction can be inhibited completely by pure cytolipin R showing that (a) immune hemolysis can be mediated through lipid determinants in the membrane, and (b) that cytolipin R determinants are present in the intact erythrocyte membrane and exposed on the surface.[PMID:4110375] 

publication : 893368|4375678|51702|186204|4110375|5068000|24174198|6072378|389925|[https://pubmed.ncbi.nlm.nih.gov/7054174 7054174 

definition : A ceramide tetrahexoside isolated from rat lymphosarcoma. The structure of cytolipin R to be N-acetylgalactosaminyl(beta1-->3)galactosyl(alpha1-->3) galactosyl(beta1-->4)glucosyl ceramide.[PMID:5068000] 

term_xref : GlycoMotif:GGM.000083|GTC:G57710SU|CID:91855936|KEGG:G00392|CHEBI:152175|SugarBind_Ligand:17  

synonyms :  

function :  

disease_associations : Actinomycosis[SugarBind_Ligand:17] 

wikipedia :  

essentials_of_glycobiology :  

GSD000054

term (main_entry) : Dermatan sulfate 

glycan_dictionary_accession : GSD000054 

glytoucan_accession  :  

term_in_sentence : By utilizing sophisticated separation methods followed by compositional analysis, domain mapping, and tandem mass spectrometry coupled with analysis by a modified genetic algorithm approach, the structural motif for the decorin dermatan sulfate chain was determined.[PMID:29111696] 

publication : 27526113]|29111696|29891297|26164146|30869126|7789716|8597249|12512856| 31250530| 17928217|12213784|27226567|31455633|28091940|19075609|31071403|15078125|18661328|20581662|17239765|15749837|2777747|20632047|8930750|7762784|31006321|26876822|1522290|131009|26986023|8161353|15315969|12543559|30637950|2525357|18156656|9692613|9200333|19661164|2299256|16075147|1126924|9774430|8537360|15563459|21077227|23275130|17137817|6447930|6209270 

definition : Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated β1→4-linked L-iduronyl-(α1→3)-N-acetyl-D-galactosamine units.[CHEBI:18376] 

term_xref : CHEBI:18376|CID:32756 

synonyms : beta-Heparin|Chondroitin sulfate B|Dermatan L-iduronate 

function : Wound healing[Essentials of Glycobiology:Chapter 7]|maintain the structure of the dermis.[Essentials of Glycobiology:Chapter 41] 

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000055

term (main_entry) : Desialylated 

glycan_dictionary_accession : GSD000055 

glytoucan_accession  :  

term_in_sentence : Furthermore, we found no evidence for "desialylated" apoB100 glycans in any of the samples analyzed.[PMID:11588155] 

publication : 30015642|26168491|29492899|31774586|32321401|23780974|7600681|18045697|1450583|4137057|28911304|27562992|29950245|31978220|2408573|8612720|10910970|27195066|1434544|22175031|24517196|29794068|30101537|18972200|1478792|4440781|21229239|30844664|31351722|31330845|1872910 

definition : A glycan from which sialyl groups have been removed. [https://en.wiktionary.org/wiki/desialylated] 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000056

term (main_entry) : Desialylated tetrasaccharide 

glycan_dictionary_accession : GSD000056 

glytoucan_accession  :  

term_in_sentence : The structures of a desialylated tetrasaccharide , two monosialylated trisaccharides , and five other minor products were defined.[PMID:8384526] 

publication : 8384526 

definition : A tetrasachharide (four branches) glycan from which sialyl groups have been removed.  

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 17

GSD000057

term (main_entry) : Difucosylated tetra-antennary N-glycans 

glycan_dictionary_accession : GSD000057 

glytoucan_accession  :  

term_in_sentence : While fucosylated N-glycans derived from serum haptoglobin of patients with CP slightly increased, di-fucosylated tetra-antennary N-glycans were observed only at this site in PC patients, and were absent in the haptoglobin of normal controls and individuals with CP.[PMID: 18214858] 

publication : 18214858 

definition : The tetra-antennary N-linked glycans that have four GlcNAc branches linked to the core and two fucose added. 

term_xref :  

synonyms :  

function :  

disease_associations : pancreatic cancer[PMID:18214858] 

wikipedia :  

essentials_of_glycobiology :  

GSD000058

term (main_entry) : Dimeric Lewis x 

glycan_dictionary_accession : GSD000058 

glytoucan_accession  : G79535HZ 

term_in_sentence : The carbohydrate antigen dimeric Lewis X (DimLex), which accumulates in colonic and liver adenocarcinomas, is a valuable target to develop anti-cancer therapeutics.[PMID:32957489] 

publication : 32957489|31276881|12062524|15488731|1979361|8737237|17939723|7683631|11384108|11133015|17388629|15483381|12662048|3233598|18618154|21892456 

definition : A six-membered glucosamine oligosaccharide consisting of two repeating units of β-D-Gal-(1→4)-[α-L-Fuc-(1→3)]-β-D-GlcNAc joined by a (1→3)-linkage.[CHEBI:61325] 

term_xref : GTC:G79535HZ|GlycoEpitope:EP0093|CID:50909845|CHEBI:61325|GlycoMotif:GGM.000031 

synonyms : DimLex^x|dimeric Le(x)|Lex-Lex|diLe(x)|Lewisx-Lewisx 

function : cancer-associated antigen[GlycoEpitope:EP0093] 

disease_associations : colonic cancer[GlycoEpitope:EP0093]|liver cancer[GlycoEpitope:EP0093] 

wikipedia :  

essentials_of_glycobiology : Chapter 14

GSD000059

term (main_entry) : Diphosphorylated Man6 

glycan_dictionary_accession : GSD000059 

glytoucan_accession  : G54792LL 

term_in_sentence : Here we report that the single-chain variable domain (scFv) M6P-1 is a unique antibody fragment with specificity for Man6P monosaccharide that, through an array-screening approach against a number of phosphorylated N-glycans, is shown to bind mono- and diphosphorylated Man6 and Man7 glycans that contain terminal αMan6P(1 → 2)αMan(1 → 3)αMan.[PMID:26503547] 

publication : 26503547 

definition :  

term_xref : GTC:G54792LL|GlycoMotif:GGM.000054

synonyms : Diphosphorylated Man_6 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000060

term (main_entry) : Disialosyl globopentaosylceramide 

glycan_dictionary_accession : GSD000060 

glytoucan_accession  : G97932OH 

term_in_sentence : Disialosyl globopentaosylceramide (DSGb5) is often expressed by renal cell carcinomas.[PMID:31339142] 

publication : 31339142|24637536|25864532|27344728| 12084983 12084983| 32567311|28205070|20663960|18214042 

definition : Disialosyl globopentaosylceramide (DSGb5) is a ganglioside originally isolated from tissue extracts of renal cell carcinoma (RCC) with metastasis.[PMID:28205070] 

term_xref : GlycoMotif:GGM.000082|GTC:G97932OH|GlycoEpitope:EP0098|CID:91860287|KEGG:G00181|SugarBind_Ligand:57  

synonyms : DSGb5|Disialosyl Gb5|V3NeuAcIV6NeuAc-Gb5Cer|Disialosylgalactosylgloboside 

function : promotes metastasis[PMID:28205070] 

disease_associations : prostate cancer[PMID:24637536]|renal cell carcinoma/RCC[GlycoEpitope:EP0098]|Pyelonephritis[SugarBind_Ligand:57] 

wikipedia :  

essentials_of_glycobiology :  

GSD000061

term (main_entry) : Disialyl Gb5 

glycan_dictionary_accession : GSD000061 

glytoucan_accession  : G97932OH 

term_in_sentence : The major disialoganglioside antigen isolated from ACHN cells, showing specific reactivity with 5F3, was characterized unequivocally as disialosyl Gb5 (V(3)NeuAcIV(6)NeuAcGb5) by identification of the core structure as globopentaosylceramide (Gb5) after enzymatic and acid hydrolysis, and by 2-dimensional (1)H-NMR spectroscopy.[PMID: 12084983] 

publication : 12084983 12084983 

definition :  

term_xref : GlycoEpitope:EP0098|GTC:G97932OH|CID:  91860287|SugarBind_Ligand:57|KEGG:G00181  

synonyms :  

function :  

disease_associations : renal cell carcinoma/RCC[GlycoEpitope:EP0098]|Pyelonephritis[SugarBind_Ligand:57] 

wikipedia :  

essentials_of_glycobiology :  

GSD000062

term (main_entry) : Disialyl I 

glycan_dictionary_accession : GSD000062 

glytoucan_accession  : G54937EM 

term_in_sentence : Here we present an example of promotion of binding of soluble-form FN from placenta or from hepatoma cells, having a specific carbohydrate epitope termed "disialyl-I," to K562 or VA13 cell surface in the presence of glycosphingolipid Gg3, which interacts specifically with disialyl-I[PMID:10640401] 

publication : 10640401 

definition :  

term_xref : GlycoEpitope:EP0095|GTC:G54937EM|CID:91849523  

synonyms : disialyl-I 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000063

term (main_entry) : Disialyl Lewis a 

glycan_dictionary_accession : GSD000063 

glytoucan_accession  : G93400AK 

term_in_sentence : Biosynthesis of disialyl Lewis a (Lea) was analyzed using previously cloned ST6GalNAc V and ST6GalNAc VI, which were responsible for the synthesis of alpha-series gangliosides.[PMID:12668675] 

publication : 12668675|17760270|15231659|12668106|30716533|32050430|22467657 

definition : Disialyl Lewis is a sialyl Lewis a with an additional sialic acid attached at the C-6 position of penultimate GlcNAc. [PMID:15231659] 

term_xref : GTC:G93400AK |GlycoEpitope:EP0040|CID:91854138|CHEBI:155549 

synonyms : disialyl Lea 

function : The 2-3,2-6 disialyl Lea determinant on epithelial cells may play a role in protecting normal epithelial cells.[GlycoEpitope:EP0040] 

disease_associations : Mucin antigen carrying 2-3 sialylated Le a antigen or 2-3, 2-6 disialylated Lc4 antigen in cancer patients had the lowest carbohydrate/protein ratio. Thus, the carbohydrate/protein ratio in the type 1 chain mucin antigens in sera of normal subjects is higher than that in sera of cancer patients.[GlycoEpitope:EP0040] 

wikipedia :  

essentials_of_glycobiology :  

GSD000064

term (main_entry) : Disialyl T antigen 

glycan_dictionary_accession : GSD000064 

glytoucan_accession  : G01614ZM 

term_in_sentence : The most potent glycoside was disialyl T antigen (NeuAcalpha2-3Galbeta1-3[NeuAcalpha2-6]GalNAc-R), followed by 3-sialyl T antigen (NeuAcalpha2-3Galbeta1-3GalNAc-R), structures expressed on O-linked glycoproteins as well as on gangliosides.[PMID: 15701648] 

publication : 29113555|17974963|33242079|12645620|15701648|26598643 

definition : α-Neup5Ac-(2→6)-[α-Neup5Ac-(2→3)-β-D-Galp-(1→3)]-α-D-GalpNAc in which the anomeric configuration of the reducing-end N-acetyl-D-glucosamine residue is α.[CHEBI:71602] 

term_xref : GlycoMotif:GGM.000014|GTC:G01614ZM|CID: 70698317|CHEBI:71602|GlycoEpitope:EP0023|KEGG:G00027  

synonyms : di-sialyl T antigen|disialyl-T antigen|disialylated T-antigen 

function : associated with von Willebrand factor(VWF) plasma levels[GlycoEpitope:EP0023] 

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000065

term (main_entry) : Disialylated biantennary 

glycan_dictionary_accession : GSD000065 

glytoucan_accession  :  

term_in_sentence : FAB-MS, electrospray-mass spectrometry, and linkage analysis demonstrated that each monomer of rat CRP contained one oligosaccharide chain , predominantly a disialylated biantennary structure , attached to Asn-128.[PMID:8486673] 

publication : 22426998|17171781|25022802|24812685|24780636|26582205|9499382|22978794|22594947|8486673|20356825|1634621|9244386|12966096|1472054| 24243045|19579232|27943633 

definition : A biantennary glycan with two GlcNAc branches linked to the core and the addition of two sialic acid residues. 

term_xref :  

synonyms : disialylated diantennary 

function : appears in human transferrin[PMID:  24243045]|Appears in human apolipoprotein (apo) B-100.[PMID:2344297] 

disease_associations : galactosemia.[PMID: 9499382] 

wikipedia :  

essentials_of_glycobiology :  

GSD000066

term (main_entry) : Disialylated biantennary complex-type 

glycan_dictionary_accession : GSD000066 

glytoucan_accession  :  

term_in_sentence : The glycan was shown to be a disialylated biantennary complex type oligosaccharide N-linked to 318 Asn.[PMID:11738084] 

publication : 11738084|9499382|9244386|24243045|12966096|25124522|19371135 

definition : A biantennary complex glycan with two GlcNAc branches linked to the core and the addition of two sialic acid residues. 

term_xref :  

synonyms :  

function : appears in human transferrin[PMID:24243045]|Appears in human apolipoprotein (apo) B-100.[PMID:2344297] 

disease_associations : galactosemia.[PMID:9499382] 

wikipedia :  

essentials_of_glycobiology :  

GSD000067

term (main_entry) : Disialylated fucosylated 

glycan_dictionary_accession : GSD000067 

glytoucan_accession  :  

term_in_sentence : Disialylated fucosylated and monosialylated non-fucosylated oligosaccharides were also identified.[PMID:17591618] 

publication : 17591618 

definition : A fucosylated glycan with two sialic acid components. 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 45

GSD000068

term (main_entry) : Forssman antigen 

glycan_dictionary_accession : GSD000068 

glytoucan_accession  : G80062GG 

term_in_sentence : Here we report the crystal structure of the complex between SLL-2 and Forssman antigen tetrasaccharide (GalNAcα1-3GalNAcβ1-3 Galα1-4 Galβ at 3.4 √Ö resolution).[PMID:28510705] 

publication : 28510705|31933576| 28134301|7021748|1802714|7512587|7747818|23325748|268649|31816281|22015168|4147161|2857159|6267170|7293775|13367419|20636540| 10460829  10460829|23255552|2675268|18955372|7020692|31784953|4114942|31273262|6257673|7696847|1916901|11169215|48262|26022515|6175621|31404475|6983878|8381954| 10431785|3257757|6792413|25039359 

definition : A linear amino pentasaccharide comprising N-acetyl-α-D-galactosamine, N-acetyl-β-D-galactosamine, α-D-galactose, β-D-galactose and β-D-glucose residues linked sequentially (1→3), (1→3), (1→4) and (1→4).CHEBI:85789 

term_xref : GTC:G80062GG |GlycoEpitope:EP0037|CID 91825690|CHEBI:85789 

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 45

GSD000069

term (main_entry) : Forssman glycolipid 

glycan_dictionary_accession : GSD000069 

glytoucan_accession  : G80062GG 

term_in_sentence : Analysis of metabolically labeled glycolipids released into the apical and basal culture medium, either as shed membrane vesicles or in budding viruses, also demonstrated the presence of the Forssman glycolipid on both apical and basolateral membranes of polarized cells.[PMID:3040119] 

publication : 3040119|268649|23240079|28134301|3495590|1138893| 10460829|10506200|8855242|1955453|1933935|3355161|6773959|14573676|29898878|10431785|1747956|11214737|7423202|389939|3871816|6187373|16133832|469271|3753492|2695680|7037611|25703376|23798992|414913|1868069| 7960243 

definition : A linear amino pentasaccharide comprising N-acetyl-α-D-galactosamine, N-acetyl-β-D-galactosamine, α-D-galactose, β-D-galactose and β-D-glucose residues linked sequentially (1→3), (1→3), (1→4) and (1→4).[CHEBI:85789] 

term_xref : GlycoMotif:GGM.000084|GTC:G80062GG|CID:91825690|KEGG:G00095|CHEBI:85789|GlycoEpitope:EP0037|SugarBind_Ligand:86 

synonyms : Forssman antigen|Globopentosylceramide 

function : an antigenic marker for a major subpopulation of macrophages from murine spleen and peripheral lymph nodes[PMID:3495590] 

disease_associations : Pyelonephritis[SugarBind_Ligand:86]|Acute cystitis[SugarBind_Ligand:86] 

wikipedia :  

essentials_of_glycobiology : Chapter 45

GSD000070

term (main_entry) : Fucose-containing tetraantennary 

glycan_dictionary_accession : GSD000070 

glytoucan_accession  :  

term_in_sentence : The two major N-linked oligosaccharides of Namalwa EPO were fucose-containing tetraantennary and fucose-containing triantennary structures.[PMID:2550193] 

publication : 2550193 

definition : A tetraantennary glycan with four GlcNAc branches linked to the core and the addition of fucose. 

term_xref :  

synonyms :  

function :  

disease_associations :  

wikipedia : https://en.wikipedia.org/wiki/Forssman_antigen 

essentials_of_glycobiology : Chapter 14

GSD000071

term (main_entry) : Fucosyl GM1 

glycan_dictionary_accession : GSD000071 

glytoucan_accession  : G91532KA 

term_in_sentence : Unique localization of fucosyl GM1 implicates its possible role in cell adhesion and recognition in the nervous system.[PMID:8068725] 

publication : 6619101|16880505|9089399|29789847|8068725|19556222|1660040|2420639|9076515|15926079|19555091|2541996|16211870|1336587|21174147|14967068|18923900|30021910|16941490|27070150|8305235|10602885|2645049|7993838|10537341|3002616|8336147|15447995|8905401|11714535|9260862|32228455|3315641|8076384|2317201|3680254|6403518 

definition : A branched amino hexasaccharide consisting of the linear sequence α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-D-Glc having a Neu5Ac residue attached to the inner galactose via an α-(2→3) linkage.[CHEBI:62686] 

term_xref : GTC:G91532KA |GlycoEpitope:EP0049|CID: 53356699|CHEBI:62686 

synonyms :  

function :  

disease_associations : small-cell lung cancer(SCLC)[GlycoEpitope:EP0049]|hepatoma[GlycoEpitope:EP0049] 

wikipedia :  

essentials_of_glycobiology :  

GSD000072

term (main_entry) : Fucosylated asialo-biantennary 

glycan_dictionary_accession : GSD000072 

glytoucan_accession  :  

term_in_sentence : We found that approximately 63% of the total N-linked oligosaccharides were of the complex type, with bisialo-biantennary (28%), asialo-biantennary (7%), fucosylated bisialo-biantennary (25%), and fucosylated asialo-biantennary (3%) oligosaccharides representing the major complex-type carbohydrate species.[PMID:2065054] 

publication : 2065054|17013932 

definition : Describing a biantennary oligosaccharide that has no sialic acid component but has fucose. 

term_xref :  

synonyms : fucosylated asialo-diantennary 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000073

term (main_entry) : Fucosylated biantennary 

glycan_dictionary_accession : GSD000073 

glytoucan_accession  :  

term_in_sentence : The profiles of the PSA N-glycans from the free and complexed molecules were quite similar to each other and consisted of fucosylated biantennary oligosaccharides as the major class.[PMID:17956937] 

publication : 17956937|30525457|1933856 

definition : a biantennary glycan with two GlcNAc branches linked to the core and the addition of fucose. 

term_xref :  

synonyms : fucosylated bisialo-diantennary 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000074

term (main_entry) : Fucosylated bisialo-biantennary 

glycan_dictionary_accession : GSD000074 

glytoucan_accession  :  

term_in_sentence : We found that approximately 63% of the total N-linked oligosaccharides were of the complex type, with bisialo-biantennary (28%), asialo-biantennary (7%), fucosylated bisialo-biantennary (25%), and fucosylated asialo-biantennary (3%) oligosaccharides representing the major complex-type carbohydrate species.[PMID:2065054] 

publication : 2065054 

definition : Describing a biantennary oligosaccharide that has two sialic acid component and fucose added. 

term_xref :  

synonyms : Fucosylated biantennary 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000075

term (main_entry) : Fucosylated LDN 

glycan_dictionary_accession : GSD000075 

glytoucan_accession  : G02240AO 

term_in_sentence : To date, oligomeric LDN and oligomeric fucosylated LDN (LDNF) have been found only on N-glycans from mammalian cells engineered to express Caenorhabditis elegansbeta4-GalNAc transferase and human alpha3-fucosyltransferase IX [Z. S. Kawar et al. (2005) J Biol Chem280, 12810-12819]. [PMID:16403022] 

publication : 16403022|28151933|19545571|22448293 

definition : An amino trisaccharide comprising an acetamido-β-D-galactose and an α-L-fucose attached to an acetamidoglucose by 1→4 and 1→3 linkages, respectively.[CHEBI:61864] 

term_xref : GlycoMotif:GGM.000017|GTC:G02240AO|GlycoEpitope:EP0151|CID: 52921591|CHEBI:61864|MeSH:C488538|KEGG:G01594 

synonyms : LDNF|Fucosylated lacdiNAc|LDN-F|(GalNAc)1 (GlcNAc)1 (LFuc)1 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000076

term (main_entry) : Fucosylated N-glycans 

glycan_dictionary_accession : GSD000076 

glytoucan_accession  :  

term_in_sentence : Haptoglobin , an acute phase protein , has four potential N-glycosylation sites , although it remains unknown which site is responsible for the change in fucosylated N-glycans.[PMID:[https://pubmed.ncbi.nlm.nih.gov/18214858 18214858 18214858]] 

publication : 18214858|31141660|26869352|29790113|31931062 

definition : The fucose from GDP-fucose is transferred to N-linked glycans. 

term_xref :  

synonyms :  

function :  

disease_associations : pancreatic cancer.[PMID: 26869352] 

wikipedia :  

essentials_of_glycobiology :  

GSD000077

term (main_entry) : Fucosylated triantennary 

glycan_dictionary_accession : GSD000077 

glytoucan_accession  :  

term_in_sentence : Asn184 is only partially glycosylated and substituted by fucosylated triantennary and small amounts of diantennary N-acetyllactosaminic glycans.[PMID:2513186] 

publication : 2513186|29642865|7679920|31110965|2551687|15051952|12943224 

definition : A triantennary glycan with three GlcNAc branches linked to the core and the addition of fucose. 

term_xref :  

synonyms :  

function : appears in human alpha-fetoprotein (AFP).[PMID: 7679920] 

disease_associations : neoplastic diseases of the liver[PMID: 7679920] |hepatocellular carcinoma[PMID:  7679920]. 

wikipedia :  

essentials_of_glycobiology : Chapter 43

GSD000078

term (main_entry) : Galabiosylceramide 

glycan_dictionary_accession : GSD000078 

glytoucan_accession  : G67988RO 

term_in_sentence : LacCer and its structural isomer, galabiosylceramide (Gb2, Galβ(1,4)Galβ-ceramide), are classified as ceramide dihexosides (CDH).[PMID:33360824] 

publication : 33360824|29099167|25582508|2824515|4027258|32854306|32868283|31319156|29530250|27367163|2564247|27727434|10216186| 10460829|24992926|23590301|15702404|1854798|14761135|3600200|8603914|8601603|1965141|17400502|3840690|15959771|7930586|7721812|17095952|2500499|3815386|8842706|10746023|3928791|3782065|6440894 

definition : A disaccharide consisting of β-D-galactopyranose having a D-galactopyranosyl residue attached at the 4-position via an α-linkage.[CHEBI:59314] 

term_xref : GlycoEpitope:EP0113|GTC:G67988RO|CID: 5288350|KEGG:G00497|KEGG:G10645|CHEBI:59314 

synonyms :  

function :  

disease_associations : tumor/lung[GlycoEpitope:EP0113]|tumor/gallbladder[GlycoEpitope:EP0113]|tumor/kidney[GlycoEpitope:EP0113]|tumor/pancreas[GlycoEpitope:EP0113] 

wikipedia :  

essentials_of_glycobiology :  

GSD000079

term (main_entry) : Galactosylceramide 

glycan_dictionary_accession : GSD000079 

glytoucan_accession  : G65889KE 

term_in_sentence : Galactosylceramide improved behavioral, neuropathological, and biochemical parameters in Cln3 Cln3 Δex7/8 mice, paving the way for effective therapy for CLN3 disease and use of serum ceramide as a potential biomarker to track impact of therapies.[PMID:31393621] 

publication : 31393621|19941861|9883654|33006978|26735924|22032265|18035062|25129050|2802541|1761517|28660574|475780|2302222 

definition :  

term_xref : GTC:G65889KE|GlycoEpitope:EP0074|SugarBind_Ligand:1|GlycoMotif:GGM.000061

synonyms : GalCer|Galactocerebroside|LC 

function :  

disease_associations : Pleuropneumonia[SugarBind_Ligand:1]|Porcine fibrinohemorrhagic necrotizing pleuropneumonia[SugarBind_Ligand:1]|Lyme disease[SugarBind_Ligand:1]|Plague[SugarBind_Ligand:1]|Acquired immune deficiency syndrome[SugarBind_Ligand:1] 

wikipedia :  

essentials_of_glycobiology :  

GSD000080

term (main_entry) : Galnac disialyl Lc4 (Hexasaccharide) 

glycan_dictionary_accession : GSD000080 

glytoucan_accession  : G33532XU 

term_in_sentence : Therefore, a new marker for prostate cancer is urgently required. We examined expression of a novel carbohydrate antigen, beta1,4-GalNAc-disialyl-Lc(4), defined by the monoclonal antibody RM2, in prostate cancer using 75 cases of radical prostatectomy specimens.[PMID: 12084983] 

publication : 15704108|11278988|12084983|7509790 

definition : (2R,4S,5R,6R)-5-Acetamido-2-[[(2R,3S,4R,5R,6S)-5-acetamido-4-[(2R,3R,4R,5S,6R)-4-[(2S,4S,5R,6R)-5-acetamido-2-carboxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxan-2-yl]oxy-5-[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxy-6-[(3R,4S,5S,6R)-2,3,5-trihydroxy-6-(hydroxymethyl)oxan-4-yl]oxyoxan-2-yl]methoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid is a member of neuraminic acids.[CID: 91857945] 

term_xref : GlycoEpitope:EP0097|GTC:G33532XU|CID: 91857945|CHEBI:149360 

synonyms :  

function :  

disease_associations : prostate cancer[GlycoEpitope:EP0097]|renal cell carcinoma/RCC[GlycoEpitope:EP0097] 

wikipedia :  

essentials_of_glycobiology :  

GSD000081

term (main_entry) : Gb5 

glycan_dictionary_accession : GSD000081 

glytoucan_accession  : G99053DY 

term_in_sentence : LnbB, a member of the glycoside hydrolase family 20 isolated from Bifidobacterium bifidum, was shown to release GNB from Gb5 and GA1 oligosaccharides.[PMID:25839135] 

publication : 12401210|25839135|31540393|31140679|3028540|3674263|31339142|30026902|10721708|30671362|26176557|25039255|24044869|32567311|27857717|21491978|24910250|29077212|8014006|27107335|32679486|1747956|8679447|28352526|11341836|10837462| 7960243|16158941|3297853|2431136|21734356|8625206|30732055|12716912|20128040|2582447|14659673 

definition : A linear amino pentasaccharide comprising D-glucose at the reducing end with a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-α-D-galactosyl-(1→4)-β-D-galactosyl moiety at the 4-position.[CHEBI:141842] 

term_xref : GlycoMotif:GGM.000076|GTC:G99053DY|CID:53239691|KEGG:G00097|CHEBI:62311|SugarBind_Ligand:12

synonyms : Globopentaosylceramide 

function :  

disease_associations : Pyelonephritis[SugarBind_Ligand:12]|Actinomycosis[SugarBind_Ligand:12|Influenza[SugarBind_Ligand:12] 

wikipedia :  

essentials_of_glycobiology : Chapter 11

GSD000082

term (main_entry) : GD1 

glycan_dictionary_accession : GSD000082 

glytoucan_accession  : G81983KG 

term_in_sentence : Hormonal and metabolic disturbances observed in both adult and paediatric patients with Gaucher disease type 1 (GD1) are discussed in this review. The PubMed database was used to identify articles on endocrine and metabolic disorders in GD1.[PMID:31791361] 

publication : 5652802|25345088|31791361|29361370|31234327|30264864|25250137|7528216|31669751|20684311|16306603|10420586|7766692|31614613|26384672|31613991|19210136|8926633|29696051|32300455|7513313|26674302|20336376|24259734|31704237|21067946|30516933|27979707|26345314|30516941|31849452|27789132|30218706|29388611|20177787 

definition :  

term_xref : GlycoMotif:GGM.000105|GTC:G81983KG|CID: 91859783|KEGG:G00126  

synonyms : GD1c 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000083

term (main_entry) : GD1a 

glycan_dictionary_accession : GSD000083 

glytoucan_accession  : G46677TE | G45714BQ

term_in_sentence : Exclusive exposure of rat oligodendrocytes to GD1a, but not other gangliosides, overcomes aggregated fibronectin-induced inhibition of myelin membrane formation, in vitro, and OPC differentiation in fibronectin aggregate containing cuprizone-induced demyelinated lesions in male mice. [PMID: 28899916] 

publication : 28899916|26860251|21930390|32906699|26054879|29951721|11745410|17653976|26119566|21554929|18435913|15342262|26865725|21151139|15716397|21492147|16942752|26973195|24449473|14999485|22735313|20589721|10521808|22929125|7827024|16897174|25062498|17227759 

definition : A branched amino hexasaccharide consisting of the linear sequence α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to a galactose via an α-(2→3) linkage. The oligosaccharide of ganglioside GD1a.[CHEBI:59209] 

term_xref : GlycoMotif:GGM.000106|GlycoMotif:GGM.000107|GTC:G46677TE|GTC:G45714BQ|CID:45266861|CHEBI:59209|GlycoEpitope:EP0056|SugarBind_Ligand:22|KEGG:G00111  

synonyms : GD1alpha 

function :  

disease_associations : Gastroenteritis[SugarBind_Ligand:22]|Actinomycosis[SugarBind_Ligand:22]|Lazy leukocyte syndrome[SugarBind_Ligand:22]|Toxoplasmosis[SugarBind_Ligand:22]|Lyme disease[SugarBind_Ligand:22]|Botulism[SugarBind_Ligand:22]|Keratoconjunctivitis[SugarBind_Ligand:22]|Influenza[SugarBind_Ligand:22] 

wikipedia :  

essentials_of_glycobiology :  

GSD000084

G37184KW

term (main_entry) : GD1b 

glycan_dictionary_accession : GSD000084 

glytoucan_accession  : G37184KW 

term_in_sentence : Gangliosides have been known to play a role in the regulation of apoptosis in cancer cells. This study has employed disialyl-ganglioside GD1b to apoptosis in human breast cancer MCF-7 cells using exogenous treatment of the cells with GD1b and endogenous expression of GD1b in MCF-7 cells.[PMID: 27144558] 

publication : 27144558|24859332|18625966|7945223|32518172|26710925|31837178|20594196|30985655|11511306|1742806|11123278|7685064|2709011|33279873|22929125|9179156|17964572|8821498|32726962|26560950|2611779|10072058|20030259|16415013|10797556|11342695|8619520|21519903|16199892|23777091|30246056|10481046 

definition : A branched amino hexasaccharide comprising a β-D-galactosyl-(1→4)-β-D-glucose disaccharide, the galactosyl residue of which carries β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl and N-acetyl-α-neuraminyl-(2→8)-N-acetyl-α-neuraminyl disaccharide units through (2→4) and (2→3) linkages respectively. It is the carbohydrate portion of ganglioside GD1b.[CHEBI:59222] 

term_xref : GlycoMotif:GGM.000108|GTC:G37184KW|CID:45266846|CHEBI:59222|GlycoEpitope:EP0059|SugarBind_Ligand:14  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 47

GSD000085

term (main_entry) : GD2 

glycan_dictionary_accession : GSD000085 

glytoucan_accession  : G02657AK 

term_in_sentence : Ganglioside GD2 is a tumor-associated surface antigen found in a broad spectrum of human cancers and stem cells. [PMID: 25440605] 

publication : 28154831|32002293|32733795|28145567|31500597|31903906|29180536|28415563|25440605|30617136|25604432|30198960|31075227|31721713|30955398|32195035|27304202|31015228|31653037|31016728|30670592|30613134|29221154|30027525|29442009|31762628|30485077|25642322| 29436609|29151270|24773917|30612272|27654028|26298772 

definition : A branched amino pentasaccharide consisting of a linear sequence of two α-sialyl residues, a β-D-galactosyl residue and an N-acetyl-β-D-glucosamine residue linked respectively (2→8), (2→8) and (1→4), to the galactosyl residue of which is also linked (1→4) an N-acetyl-β-D-glucosaminyl residue. It is the carbohydrate portion of ganglioside GD2.[CHEBI:59218] 

term_xref : GlycoMotif:GGM.000094|GTC:G02657AK|CID:45266844|CHEBI:59218|GlycoEpitope:EP0061|SugarBind_Ligand:88  

synonyms :  

function :  

disease_associations : breast cancer[PMID:28415563] 

wikipedia :  

essentials_of_glycobiology : Chapter 11|Chatper 35

GSD000086

term (main_entry) : GD3 

glycan_dictionary_accession : GSD000086 

glytoucan_accession  : G98544DH 

term_in_sentence : In mammalian cells, the intracellular accumulation of ganglioside GD3, an acidic glycosphingolipid, contributes to mitochondrial damage, a crucial event during the apoptopic program. [PMID: 12531552] 

publication : 30245960|27591028|12531552|29069780|12470841|29436609|28295752|27304202]|31138648|27288875|30446565|8721669|3903474|16081368|32743804|24372645|26792897|20890432|25330147|20581115|11174200|16040804|23783008|17368571|11023989|12901230|21807667|7061953|2231782|19423750|22632091|18202973|6392333|15896784|8261439|20052288|12847141|12486096|12118012|19912988|22795094|18655184|17043769|21395555|2472199|19776077 

definition : A linear amino tetrasaccharide consisting of two sialyl, one galactose and one glucose residue (at the reducing end) connected by sequential α-(2→8)-, α-(2→3)- and β-(1→4)-linkages. The oligosaccharide of ganglioside GD3.[CHEBI:59210] 

term_xref : GlycoMotif:GGM.000091|GTC:G98544DH|CID:45266862|CHEBI:59210|GlycoEpitope:EP0062|SugarBind_Ligand:89|MeSH:C509062  

synonyms :  

function :  

disease_associations : Cholera[SugarBind_Ligand:89]|Influenza[SugarBind_Ligand:89] 

wikipedia :  

essentials_of_glycobiology : Chapter 11

GSD000087

term (main_entry) : Globoside 

glycan_dictionary_accession : GSD000087 

glytoucan_accession  : G00061MO 

term_in_sentence : Results of TLC immunostaining of neutral glycolipids from the cDNA-transfected cells also supported the identity of the newly synthesized component as globoside. [PMID:10993897] 

publication : 10993897 

definition :  

term_xref : GlycoMotif:GGM.000070|GTC:G00061MO  

synonyms : Cytolipin K|Gb4|Globoside I|Globotetraosylceramide|P antigen 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 47

GSD000088

term (main_entry) : Globotetraosylceramide 

glycan_dictionary_accession : GSD000088 

glytoucan_accession  : G00061MO 

term_in_sentence : Here we report that PUGNAc treatment provokes globotetraosylceramide (Gb4Cer) accumulation in human umbilical vein endothelial cells (HUVEC).[PMID:28392398] 

publication : 28392398|25787850|23471986|2559078|32455599|2663859|32796033|3517161|20082214|30853699|15279935|26104834|20732996|30224239|31142708|30338271|25033755|30413389|7104376|29866658|24983355|6794884|31361021|21740983|33168837|31752441|28123520|29068380|24841197|27932383|28535204|31691795|27916888|27558838|10227680|26464281|22348006|22279060|25156739|32314902|22718629|23701631|23906628|8613382|23555772|20059899|7868240 

definition : An amino tetrasaccharide consisting of 2-acetamido-2-deoxy-β-D-galactopyranosyl, α-D-galactopyranosyl, β-D-galactopyranosyl, and β-D-glucopyranose units joined together in sequence by (1→3), (1→4), and (1→4) glycosidic linkages, respectively.[CHEBI:145578] 

term_xref : GlycoMotif:GGM.000070|GlycoEpitope:EP0073|CID: 5288889|CHEBI:145578|SugarBind_Ligand:18|MeSH:C024032

synonyms : Gb4Cer|Gb4|Globoside|P antigen|Cytolipin K 

function :  

disease_associations : Actinomycosis[SugarBind_Ligand:18]|Pyelonephritis[SugarBind_Ligand:18]|Acute cystitis[SugarBind_Ligand:18]|Shigellosis[SugarBind_Ligand:18]|Lazy leukocyte syndrome[SugarBind_Ligand:18]|Influenza[SugarBind_Ligand:18] 

wikipedia :  

essentials_of_glycobiology :  Chapter 11

GSD000089

G00061MO

term (main_entry) : Globotriaosylceramide 

glycan_dictionary_accession : GSD000089 

glytoucan_accession  : G00059MO 

term_in_sentence : Defects in the gene encoding α-galactosidase A lead to accumulation of globotriaosylceramide (GL3) in various cell types.[PMID:32127409] 

publication : 32127409|28674962|30875019|30413389|31778662|31101366|24335674|31241709|24158513|28947349|31566927|28672034|31939530|29530250|27851774|26426881|25031264|29982630|24496231|29983334|28756410|27190352|29274327|29099167|28402705|23680766|28625968|26960552|26797827|22742555|27756537|31630715|3827883|28384397|29523338|31010832|27195818|26661087|23093409|30879639|27081853|17409683|29921669|25575293|26291612|23146289|25857295|26070511 

definition : Globotriaosylceramide is a type of globoside(glycosphingolipid) which is formed by alpha linkage of galactose to lactosylceramide. The reaction is catalyzed by enzyme A4GALT.[Wiki:Globotriaosylceramide] 

term_xref : GlycoMotif:GGM.000068|GTC:G00059MO|GlycoEpitope:EP0071|CID: 5279515|CHEBI:68485|MeSH:C018549|SugarBind_Ligand:27  

synonyms : Gb3|GL3|Pk antigen|P^K antigen|Gb(3)|Gb_3|CD77|globotriaosylceramide|ceramide trihexoside|CTH|Trihexosylceramide 

function :  

disease_associations : Pyelonephritis[SugarBind_Ligand:27]|Acute cystitis[SugarBind_Ligand:27]|Shigellosis[SugarBind_Ligand:27]|Lyme disease[SugarBind_Ligand:27]|Cutaneous lesions[SugarBind_Ligand:27]|Diarrhea[SugarBind_Ligand:27] 

wikipedia :  

essentials_of_glycobiology :  

GSD000090

term (main_entry) : Glucosylceramide 

glycan_dictionary_accession : GSD000090 

glytoucan_accession  : G71142DF 

term_in_sentence : Glucosylceramide (GlcCer), the initial GSL synthesized from ceramide by GCS (GlcCer synthase), is required for embryonic survival, but its role in the lung is unknown.[PMID:31265321] 

publication : 31265321|29290548|29627573|20919653|28427052|30550553|24415933|31914593|31051284|23073611|30146946|31619618|26840726|29750412|8065509|27412675|27840079|30611744|31353719|25661072|28686011|25803043|28865794|28154347|31466334|30242129|12531551|30639288|30864417|27711049|22764777|27905603|29077010|28744000|23555901|24115322|12803919|29204666|23628459|28851512|26136173|23563543|30110701|26572681|2193825|29926415|31727994|27479571 

definition : Cerebrosides which contain as their polar head group a glucose moiety bound in glycosidic linkage to the hydroxyl group of ceramides. Their accumulation in tissue, due to a defect in beta-glucosidase, is the cause of Gaucher's disease.[MeSH:D005963] 

term_xref : MeSH:D005963|GlycoMotif:GGM.000060|CHEBI:83264|GTC:G71142DF

synonyms : GlcCer|Glucocerebroside|Ceramide monohexoside|CMH 

function : The structural characterization of mixed membranes made of cationic lipids and glucosylceramides may be important for developing novel immunotherapeutic tools such as vaccine adjuvants.[PMID:30611744]|Glucosylceramide (GlcCer), the initial GSL synthesized from ceramide by GCS (GlcCer synthase), is required for embryonic survival, but its role in the lung is unknown.[PMID:31265321] 

disease_associations : Gaucher's Disease|Pharyngitis[SugarBind_Ligand:3]|Tracheobronchitis[SugarBind_Ligand:3]|Pleuropneumonia[SugarBind_Ligand:3]|Porcine fibrinohemorrhagic necrotizing pleuropneumonia[SugarBind_Ligand:3]|Diarrhea[SugarBind_Ligand:3] 

wikipedia :  

essentials_of_glycobiology : Chapter 31

GSD000091

G48558GR

term (main_entry) : GM1 

glycan_dictionary_accession : GSD000091 

glytoucan_accession  : G48558GR 

term_in_sentence : GM1-induced fluidization of the phospholipid membranes and probable physical contact between bulky sugar head group of GM1 and spectrin, may explain the modulatory role of GM1 on aminophospholipid interactions with nonerythroid brain spectrin.[PMID: 29920238] 

publication : 18524657|31761138|36180805|29920238|33859490|31937438|25762012|25931034|31776384|32013258|30776097|31048748|31447771|30292198|28796418|27806275|21076871|27552916|17986147|26960162|27815022|25851126|32916822|11462671|28236574|15911874|28577204|28497346|1794005|31934908|30267299|16902585|29439846|32325905|29747823|27576485|26338710|27858734|24501414|26818965|26629687|26958633|1854596|32134593|32198666|6619101 

definition : A branched amino pentasaccharide consisting of the linear sequence β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to the inner galactose via an α-(2→3) linkage. The oligosaccharide of ganglioside GM1a.[CHEBI:59208] 

term_xref : GlycoMotif:GGM.000098|GTC:G48558GR|CID:196569|CHEBI:59208|GlycoEpitope:EP0050|SugarBind_Ligand:13|KEGG:G00110 

synonyms :  GM1 ganglioside|GM1-ganglioside

function :  The branched pentasaccharide chain of ganglioside GM1 is a prominent cell surface ligand, for example, for cholera toxin or tumor growth-regulatory homodimeric galectins.[PMID:16267866]

disease_associations : GM1 gangliosidosis (GM1) [PMID: 33859490]|Gastroenteritis[SugarBind_Ligand:13]|Actinomycosis[SugarBind_Ligand:13]|Lazy leukocyte syndrome[SugarBind_Ligand:13]|Toxoplasmosis[SugarBind_Ligand:13]|Cholera[SugarBind_Ligand:13]|Botulism[SugarBind_Ligand:13] 

wikipedia : https://en.wikipedia.org/wiki/GM1 

essentials_of_glycobiology :  Chapter 11| Chapter 14 

GSD000092

term (main_entry) : GM2 

glycan_dictionary_accession : GSD000092 

glytoucan_accession  : G79389NT 

term_in_sentence : GM1 gangliosidosis has both central nervous system and systemic findings; while, GM2 gangliosidosis is restricted primarily to the central nervous system.[PMID: 27491214] 

publication : 29618308|27491214|32867370|30030044|27499644|31097363|29100724|27402091|31852956|30389374|30988135|8786814|14533808|23370522|28192816|32692591|29106755|28833537|11339652|9728335|27270764|9714704|26175473|27018595|28615102|28974375|32951593|11462672|28955902|17192692|26538065|25421609|9572057|11596983|15264019|23236285|11596984|31261761|30113798|24391178|24309906|22224667|7980537|18272501|9006924| 

definition : A branched amino tetrasaccharide consisting of the linear sequence β-D-GalNAc-(1→4)-β-D-Gal-(1→4)-β-D-Glc having a Neu5Ac residue attached to the galactose via an α-(2→3) linkage. Corresponds to the carbohydrate portion of ganglioside GM2.[CHEBI:59220] 

term_xref : GlycoMotif:GGM.000095|GTC:G79389NT|CID: 45266845|CHEBI:59220|GlycoEpitope:EP0051|SugarBind_Ligand:39|KEGG:G00109|KEGG:G10351  

synonyms :  

function :  

disease_associations : lung adenocarcinoma[GlycoEpitope:EP0051]|embryonal carcinoma[GlycoEpitope:EP0051]|germ cell tumor[GlycoEpitope:EP0051]|teratocarcinoma[GlycoEpitope:EP0051]|squamous cell carcinoma[GlycoEpitope:EP0051]|Gastroenteritis[SugarBind_Ligand:39]|Cholera[SugarBind_Ligand:39]|Clostridial myonecrosis[SugarBind_Ligand:39]|Tetanus[SugarBind_Ligand:39] 

wikipedia : https://en.wikipedia.org/wiki/GM1_gangliosidoses 

essentials_of_glycobiology : Chapter 11

GSD000093

term (main_entry) : GM3 

glycan_dictionary_accession : GSD000093 

glytoucan_accession  : G91237TK 

term_in_sentence : We also demonstrated an essential role of GM3 in murine and human auditory systems; a common pathological feature of GM3S deficiency is deafness. [PMID: 29747813] 

publication : 29376491|29747813|25613425|30318083|31526872|31004109|28019668|26434718|27313500|27539856|30111401|28544772|29407985|19364317|30190430|31297734|30091781|26043887|32183071|30665141|27873002|25801320|30209782|32378734|23050851|22768242|14993837|24934090|17638075|21518140|26102277|19759399|24502144|25303960|23564406|16636105|16491123|11259118|15102521|12724312|24985965|8496625|25403557|15690123|15939439|25893133|23591593|20634908|2004380|739008| 

definition : Ganglioside GM3 (d18:1/16:0) is a glycosphingolipid (ceramide and oligosaccharide)or oligoglycosylceramide with one or more sialic acids (i.e. n-acetylneuraminic acid) linked on the sugar chain. It is a component the cell plasma membrane which modulates cell signal transduction events. Gangliosides have been found to be highly important in immunology. Ganglioside GM3 carries a net-negative charge at pH 7.0 and is acidic. Gangliosides can amount to 6% of the weight of lipids from brain, but they are found at low levels in all animal tissuesGangliosides are glycosphingolipids. There are four types of glycosphingolipids, the cerebrosides, sulfatides, globosides and gangliosides. Gangliosides are very similar to globosides except that they also contain N-acetyl neuraminic acid (NANA) in varying amounts. The specific names for the gangliosides provide information about their structure. The letter G refers to ganglioside, and the subscripts M, D, T and Q indicate that the molecule contains mono-, di-, tri and quatra-sialic acid. The numbered subscripts 1, 2 and 3 refer to the carbohydrate sequence that is attached to the ceramide. In particular, 1 stands for GalGalNAcGalGlc-ceramide, 2 stands for GalNAcGalGlc-ceramide and 3 stands for GalGlc-ceramide. Deficiencies in lysosomal enzymes that degrade the carbohydrate portions of various gangliosides are responsible for a number of lysosomal storage diseases such as Tay-Sachs disease, Sandhoff disease, and GM1 gangliosidosis. The carbohydrate portion of the ganglioside GM1 is the site of attachment of cholera toxin, the protein secreted by Vibrio cholerae.[HMDB0004844] 

term_xref : GlycoMotif:GGM.000090|GTC:G91237TK|CID: 5288424|CHEBI:59226|GlycoEpitope:EP0053|SugarBind_Ligand:35 

synonyms :  

function : Membrane stabilizer|Energy source|Energy storage|Molecular messenger:|Signaling molecule[HMDB0004844] 

disease_associations : Gastroenteritis[SugarBind_Ligand:35]|Chronic gastritis[SugarBind_Ligand:35]|Toxoplasmosis[SugarBind_Ligand:35]|Peptic ulcerSugarBind_Ligand:35|Gastric cancer[SugarBind_Ligand:35]|Influenza[SugarBind_Ligand:35]|Diarrhea[SugarBind_Ligand:35]|Botulism[SugarBind_Ligand:35] 

wikipedia :  

essentials_of_glycobiology : Chapter 37

GSD000094

G30207PZ

term (main_entry) : GM4 

glycan_dictionary_accession : GSD000094 

glytoucan_accession  : G30207PZ 

term_in_sentence : GM4 is synthesized by the sialylation of galactosylceramide (GalCer), while the ganglioside GM3 is synthesized by the sialylation of lactosylceramide (LacCer).[PMID:23999868] 

publication : 23999868|2332419|12091485|19542236|8407875|23320941|28808804|3621237|23203271|7057115|26362868|6170387|18034482|7076644|2391348|25464080|3701369|11217952|6201236|30744426|9388026|27177620|30246056|15979459|7586078|6779816|29402905|7335153|3306476|17499534|7074082|9668345|3701884|26862430|6831238|27311552|26831445|24417799|7097284|4169231|16854400|26483798 

definition : An amino disaccharide consisting of β-D-galactose having an α-N-acetylneuraminyl residue attached at the 3-position
[CHEBI:63155] 

term_xref : GlycoMotif:GGM.000089|GTC:G30207PZ|CID:5289366|CHEBI:63155|KEGG:G00317|SugarBind_Ligand:110 

synonyms :  Sialylated GalCer

function :  

disease_associations : Chronic gastritis[SugarBind_Ligand:110]|Peptic ulcers[SugarBind_Ligand:110]|Gastric cancer[SugarBind_Ligand:110] 

wikipedia :  

essentials_of_glycobiology : Chapter 11|Chapter 15|Chapter 44|Appendix 45A 

GSD000095

term (main_entry) : GP1c 

glycan_dictionary_accession : GSD000095 

glytoucan_accession  : G93805MV 

term_in_sentence : n this report, we describe an efficient convergent synthesis of the GP1c glycolipid epitope, which is one of the most complex c-series gangliosides. [PMID:19053458] 

publication : 1606358|19053458|1695858|4091974|10775425|2468656|2299350|3064875|11432974| 9613831|11831845|1879553| 10699494|8969459|8474578|12031286|1304332|9153001|10564776 

definition :  

term_xref : GlycoMotif:GGM.000118|GTC:G93805MV

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 11|Chapter 14|Chapter 27|Chapter 35|Chapter 45 |Chapter 47|Chapter 49 

GSD000096

term (main_entry) : GQ1b 

glycan_dictionary_accession : GSD000096 

glytoucan_accession  : G18625KA 

term_in_sentence : Bilateral infusion of GQ1b into the hippocampus ameliorates cognitive deficits in the triple-transgenic AD mouse model (3xTg-AD).[PMID:31186474] 

publication : 30798387|31186474|26704905|23677659|26984947|24184316|23804237|9819299|18514410|22189683|24859332 

definition : An amino oligosaccharide that is a branched octasaccharide derivative consisting of four sialyl residues, two galactose residues, one N-acetylglucosamine and a glucose residue at the reducing end.[CHEBI:59212] 

term_xref : GlycoMotif:GGM.000115|GTC:G18625KA|GlycoEpitope:EP0069|CID:45266843|KEGG:G00117|CHEBI:59212  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 11

GSD000097

term (main_entry) : GQ1ba 

glycan_dictionary_accession : GSD000097 

glytoucan_accession  : G54733XO 

term_in_sentence : A few studies have reported the association of autoantibodies to GM1 or GQ1bα with Alzheimer's disease (AD) or vascular dementia.[PMID:25024341] 

publication : 25024341|23717411|17870542|10702226|21137678|26748510|8662799|21274438|24649890|16580208|28124591|20095613|17507233|23565921|14505645|20930939|9201997 

definition :  

term_xref : GlycoMotif:GGM.000116|GTC:G54733XO  

synonyms : GQ1balpha 

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000098

term (main_entry) : GQ1c 

glycan_dictionary_accession : GSD000098 

glytoucan_accession  : G99524KA 

term_in_sentence : The neural specific monoclonal antibody A2B5 was found to interact with GQ1c but not with Gq1b, nor did it interact with other glycolipids such as GM1, GD1a, GD1b, GT1a, GT1b and GA1.[PMID: 6640289] 

publication : 6640289| 1695858|7798936|1729139|2468656|20368669|2723647|1814411| 3064875|6085330|1613492|17883393|11831845| 10775425|8219015|8804704|1384262|7066685|2299192|9613831|10350354|1304337|9153001|11959025|8474578|2299350| 10564776|10699494|3942818|12031286|7361620 

definition : Alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-[alpha-Neu5Ac-(2->3)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->4)]-beta-D-Galp-(1->4)-beta-D-Glcp is a member of neuraminic acids and an amino octasaccharide.[CID: 91860352] 

term_xref : GlycoMotif:GGM.000117|GTC:G99524KA|CID: 91860352|CHEBI:145645|KEGG:G00121 

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology : Chapter 46

GSD000099

term (main_entry) : GT1a 

glycan_dictionary_accession : GSD000099 

glytoucan_accession  : G68110IF 

term_in_sentence : GT1a mimicry was found in the lipo-oligosaccharides of strain ICDCCJ07002 and ICDCCJ07004; but a combination of GM3/GD3 mimics was observed in ICDCCJ07001, although this patient had anti-GT1a IgG antibodies.[PMID:26197476] 

publication : 12023422|32623212|26197476|9585812|29747820|23804237|11993188|31683059|19631994|9742882|29709941|8971119|8706663|893404|31829433|8910600|30600291|29319803|26176883|29063860|6766128|31602715|29808463|30711390|29847988|30116054|28187751 

definition : A branched heptasaccharide derivative consisting of three sialyl residues, two galactose residues, one N-acetylglucosamine and a glucose residue at the reducing end.[CHEBI:59215] 

term_xref : CID:45266863|GlycoMotif:GGM.000110|GTC:G68110IF|GlycoEpitope:EP0066|KEGG:G00112|CHEBI:59215  

synonyms :  

function :  

disease_associations :  

wikipedia :  

essentials_of_glycobiology :  

GSD000100

term (main_entry) : GT1a alpha 

glycan_dictionary_accession : GSD000100 

glytoucan_accession  : G02149VR 

term_in_sentence : A new class of gangliosides, GT1a alpha and GQ1b alpha, were initially identified as cholinergic neuron-specific antigens in bovine brain. [PMID:8082783] 

publication : 7710562|8082783|10972137|9468624|9143254|8221098|9679279|11368158|11878808 

definition :  

term_xref : GlycoMotif:GGM.000111|GTC:G02149VR|GlycoEpitope:EP0111|CID: 91851751|CHEBI:156678|KEGG:G00128  

synonyms : GT1aa 

function : GT1a alpha was a cholinerginic-specific antigen.[GlycoEpitope:EP0111] 

disease_associations :  

wikipedia :  

essentials_of_glycobiology :